The effect of smoking on sensory and attentional masking

This study examined the influence of smoking on low-level sensory and higher level visual cognitive abilities. Three groups (nonsmokers, deprived smokers, and nondeprived smokers) of 22 observers were tested using a visual target discrimination task. To assess sensory and visual cognitive differences, a masking task developed by Enns and Di Lollo (1997) was used. In the task, the target was masked by either a contour mask (contour masking) or an object mask (attentional masking by object substitution). The strongest masking effects were found in the group of nondeprived smokers, for both sensory and attentional masking. This pattern of results as well as results in the deprived smokers indicated changes in transient visual processing channels due to the acute actions of nicotine, not mediated by withdrawal relief.     

The synergistic effect of smoking and serum cholesterol on coronary heart disease

Cigarette smoking is a strong predictor of coronary heart disease (CHD), but much of the variance in determining which smokers will, and which will not, suffer from CHD remains unexplained. This review examines evidence of a synergistic interaction effect of smoking and elevated serum cholesterol on CHD morbidity and mortality. Evidence is also presented to support the notion that, in part, serum cholesterol, like smoking, is an index of a behavioral risk factor. Such a synergistic interaction is determined to exist, although improvements in methodology are needed to more clearly identify its magnitude. The review suggests that behavioral treatments aimed at smoking cessation and dietary modification should be focused specifically on the more than 25 million young and middle-aged Americans who smoke and have elevated serum cholesterol. In this way, such treatments may increase their effectiveness in lowering the risk of CHD (benefit) without necessarily increasing their effort (cost).     

The effect of smoking on brainstem auditory evoked potentials in positive- and negative-symptom schizophrenia

Studying brainstem auditory evoked potentials (BAEPs) and comparing the specific waves in smokers vs nonsmokers in both positive- and negative-symptom schizophrenia may elucidate the role of smoking in information processing. BAEPs were recorded in 40 patients with schizophrenia; 20 had predominantly positive symptoms (10 smokers and 10 nonsmokers) and 20 had predominantly negative symptoms (10 smokers and 10 nonsmokers). The severity of positive and negative symptoms was assessed by scale of assessment of positive symptoms and scale of assessment of negative symptoms (SANS). The BAEP results were compared with 15 healthy control individuals matched with the patients by age, sex, and cultural background. The smokers with negative symptoms showed a significant increase in the alogia, summary, and composite scores of SANS as compared to the nonsmokers. Although, most of the BAEP abnormalities were among patients with positive symptoms. The effect of smoking on the BAEPs was only in patients with negative symptoms. We also studied the interaction between smoking factor (smokers vs nonsmokers) and group type (group with mostly positive symptoms vs group with mostly negative symptoms) on the BAEPs and found a significant difference only for the first-wave latency mainly on the right side (P=0.012). The absence of a significant effect of smoking on most of the parameters of the BAEPs on interaction with the group factor suggests that the effect of smoking on the BAEPs is more apparent when negative symptoms prevail. However, studies are warranted to substantiate this finding.     

The effects of beliefs about smoking and health on smoking cessation

The purpose of this study was to examine whether beliefs of an American sample about smoking and health, as defined by cognitive orientation theory, would determine those smoking cessation program participants who would become abstainers and those who would not. Although the smoking cessation program was not designed to influence the specific kinds of beliefs studied, subscales measuring two of the four types of beliefs differentiated participants who would become abstainers from those who would not. Abstainers tended to have stronger goal beliefs about their desire to quit smoking, and stronger beliefs about the health-related implications of smoking. Participants' beliefs that they could resist an urge to smoke, which implied the use of coping skills, were more important in determining who would abstain from smoking than was their confidence that they could quit smoking, which implied the use of willpower.     

The effects of self-modeling on cigarette smoking behavior

Two studies of self-modeling are described. Study 1 investigated whether self-modeling would inhibit cigarette smoking behavior. Fourteen cigarette smokers (four males and 10 females) served as subjects for a repeated-measures design. In the self-modeling condition, the subjects watched themselves on a television monitor while smoking; in the control condition, they watched a short cartoon film on the same monitor, also while smoking. The following were measured: (1) the amount of tobacco consumed, (2) the amount of time lit cigarettes were in contact with the subjects’ lips, and (3) the subjects’ physiological responses (GSRs). Study 2 investigated the role of cognitive factors in self-modeling. It followed much the same self-modeling procedures as Study 1. However, unlike Study 1, it incorporated a manipulated cognitive variable: attitudes toward cigarette smoking. Self-modeling reduced the amount of smoking relative to the control condition in Study 1. In Study 2 it was found that cognitive factors influenced the amount of smoking. Smoking increased in subjects supplied with information favorable to smoking, whereas it decreased in those supplied with information unfavorable to smoking. These findings and additional research on the efficacy of self-modeling relative to other procedures suggest the importance of cognitive factors in self-modeling.     

The natural history of cigarette smoking: predicting young-adult smoking outcomes from adolescent smoking patterns

Assessed the magnitude of risk that adolescent cigarette smoking carries for adult smoking. Using a longitudinal, prospective design, results indicate that even infrequent experimentation in adolescence significantly raises the risk for adult smoking and that regular (at least monthly) adolescent smoking raises the risk for adult smoking by a factor of 16 compared to nonsmoking adolescents. Relative risk was also increased by an early onset of smoking and by a stable, uninterrupted course from experimentation to regular smoking. Relative risk did not significantly vary by age or sex. The continuity of smoking behavior between adolescence and adulthood supports the importance of primary prevention programs directed at adolescent populations.     

Joint effect of dopaminergic genes on likelihood of smoking following treatment with bupropion SR.

OBJECTIVE: To determine the relationship between joint variation in 2 dopaminergic genes and the likelihood of nonsmoking following treatment with bupropion sustained release (SR). DESIGN: Three hundred twenty-three participants in a bupropion SR smoking cessation effectiveness trial with 12-month follow-up were genotyped for variants of dopamine receptor gene DRD2 and dopamine transporter SLC6A3. MAIN OUTCOME MEASURES: Self-reported 7-day point prevalence of nonsmoking. RESULTS: Neither genotype alone was associated with 7-day point-prevalent nonsmoking at the 12-month follow-up. However, in the presence of the DRD2 A1 allele, SLC6A3 status was significantly associated with the likelihood of nonsmoking at the 12-month follow-up (individuals with DRD2 A1+ and SLC6A3 9- were more likely to be smoking). In the absence of the DRD2 A1 allele, the association between SLC6A3 status and nonsmoking was nonsignificant. CONCLUSION: Although these results are suggestive, a more compelling test is needed of the hypothesis that dopaminergic gene interaction underlies, in part, the likelihood of smoking following treatment with bupropion SR. Most likely this will come from larger studies involving prospective randomization to treatment based on genotype.     

The effects of smoking and urinary pH on a detection task

Performance was measured in a detection task over a period of 50 min. Subjects were either non-smokers or smoked more than 15 cigarettes per day. No smoking was allowed during the task, but smokers were all asked to smoke a cigarette immediately before doing it. One hour previously, subjects had been given a double-blind dose of a substance which would shift the pH of their urine either upwards or downwards, by small amounts sufficient to affect the rate of renal excretion of nicotine in the smokers. The pH manipulation had no effect on the performance of the non-smokers, who improved steadily throughout the task. After some 40 min of performance, the deprived smokers showed less improvement than the non-smokers, and the smokers whose urine had been made acid improved less than those whose had been made alkaline. The results are interpreted as evidence for a phasic effect on performance of small degrees of nicotine deprivation, which has consequences for theories of nicotine dependence.     

The effects of smoking on the speaking fundamental frequency of adult women

The present study sought to investigate the effects of smoking on the speaking fundamental frequency of adult women. The results indicated that, in the reading condition, fundamental frequency for the smokers was significantly lower than fundamental frequency for the nonsmokers. Eighty-seven percent of the smokers examined by an otolaryngologist exhibited some abnormality in appearance of the vocal folds. The results also suggest that menopause may contribute to a lowering of the speaking fundamental frequency of adult women.     

The intergenerational transmission of implicit and explicit attitudes toward smoking: Predicting adolescent smoking initiation

This study examined the intergenerational transmission of implicit and explicit attitudes toward smoking, as well as the role of these attitudes in adolescents’ smoking initiation. There was evidence of intergenerational transmission of implicit attitudes. Mothers who had more positive implicit attitudes had children with more positive implicit attitudes. In turn, these positive implicit attitudes of adolescents predicted their smoking initiation 18-months later. Moreover, these effects were obtained above and beyond the effects of explicit attitudes. These findings provide the first evidence that the intergenerational transmission of implicit cognition may play a role in the intergenerational transmission of an addictive behavior.     

The influence of social environment and social image on adolescent smoking.

This purpose of this article is to explore differences by gender and school grade in patterns of association among social influences and tobacco use. Data from the 1999 (N = 15,038) and 2000 (N = 35,828) National Youth Tobacco Survey (American Legacy Foundation, 1999, 2000), a nationally representative, repeated cross-sectional survey, were used in the analysis. The authors compared effects on adolescent smoking. Direct paths from social environment to current smoking increased from middle school to high school. Indirect paths with social image mediating this relationship revealed a smaller increase. The pattern was constant across subsamples. Social image of smokers mediated the influence of social environment on adolescent smoking. Social image had a greater effect on smoking among middle school boys and high school girls.     

Quantification of manual force control and tremor

Isometric impulse frequencies associated with active tremor and force regulation were examined in 10 patients with idiopathic Parkinson's disease (PD) and in 10 older adults (OAs) who performed an isometric tracing task. The authors decoupled and analyzed the data to determine whether PD-related tremor in the thumb and in the index finger during isometric force control are related and whether PD impairs the performance of volitional force control beyond the errors contributed by tremor. After decoupling, there were clear and robust differences in PD patients' control of isometric force that could not be attributed to action-tremor error. Those errors, which occurred in the absence of movement, suggest impairment in coordinated recruitment and derecruitment of motor units during a fine-motor task.