Evidence for spatial navigational impairments in hydrocephalus patients without spina bifida

The cognitive sequelae of hydrocephalus have mostly been explored with standardised clinical tasks. The aim of the present research was determine whether impairments on these abstract tasks extend to everyday spatial and navigational behaviour. Patients with hydrocephalus, but without spina bifida, were compared to a control group on tests of searching behaviour, landmark memory, route learning, and path integration. Participants with hydrocephalus displayed reduced sensitivity to spatial cueing, less accurate route-learning, and significantly less accurate spatial updating. These data represent an important empirical demonstration of spatial navigational impairments due to hydrocephalus outside of the context of spina bifida. We discuss some of the cognitive, neural, and individual differences factors that might contribute to this particular pattern of impairments.     

Spatial navigational impairments in hydrocephalus

Whilst much is known about the neuropathological consequences of hydrocephalus, there have been comparatively few studies of the cognitive impairments associated with it. Studies using standardised tests of cognitive function have identified a general pattern of impairments, with patients exhibiting particular difficulty on tests of spatial memory and executive function. A strong prediction is that these deficits are likely to affect daily wayfinding behaviour, and we report a study of spatial and navigational abilities in a group of patients with hydrocephalus but without spina bifida. Participants completed a range of experimental tasks assessing spatial cueing behaviour, landmark memory and route-learning, and idiothetic path integration. This patient group was compared to a control sample matched on verbal, spatial, and intelligence measures, and hydrocephalus was found to be associated with relative impairments in each of the tasks. Patients exhibited reduced sensitivity to spatial cueing, less accurate route-learning, poorer memory for landmark objects, and less accurate spatial updating (with particular impairments in the calculation of heading). Overall, these data represent the first empirical demonstration of navigational impairments in hydrocephalus, and we suggest some of the cognitive, neural, and individual differences factors that may contribute to the pattern of performance reported.     

Age-related differences in the elderly in a spatial recognition task

ABSTRACT

Spatial memory is a cognitive ability which declines with ageing thus showing changes in some process such as the use of allocentric strategies. These age-related changes in spatial orientation suggest that this skill could be an adequate marker of cognitive decline. Many tasks used in investigation to assess spatial memory demand a participant’s active role, which involves that the navigational experience is different for everyone. In this study, the Almeria Spatial Memory Recognition Test (ASMRT), a test based on a recognition paradigm, was used to offer the same experience with the environment. The aim of this research was to determine if the ASMRT is suitable to be applied in the elderly and detect spatial memory differences as one age. The ASMRT and other neuropsychological tests were applied in a sample aged between 50and 79 years. Results revealed a decrease in the ASMRT performance by the older group. No gender differences were found. Performance in attention and visuospatial working memory tests revealed some correlations with the ASMRT performance. In conclusion, this study demonstrates that 70–79-year-old participants clearly show age-related changes in spatial memory. Thanks to its simplicity the ASMRT could be used as a screening test in medical practice.     

An age-related view of the role of object and spatial cognitive styles in distance estimation

Distance estimations require identifying characteristics of the object and its spatial surroundings. With the present study, we examined the relationship between visual object and spatial (cognitive) styles and distance estimations in children and adults. Participants were administered the Object-Spatial Imagery Questionnaire (OSIQ) and two distance estimation tasks—one required estimating reach distance (reach task [RT]) from the self and the other required estimating distance between targets (perceptual task[PT]). Overall, our findings indicated that age was the best predictor of estimation for RT and PT tasks, and individuals were more accurate in the task requiring an egocentric frame of reference (RT) compared to tasks that require allocentric judgements (PT). In addition, children had higher ratings on cognitive styles in comparison to adults, but both object and spatial styles only related to RT accuracy in adults. Cognitive styles seem to be associated to distance estimation accuracy, but only when there is a clear preference.     

Does aging affect the formation of new topographical memories? Evidence from an extensive spatial training

A decline in navigational abilities is a consistent feature of aging. Although many studies focused on recall of navigational information, the impact of time and type of learning on recall has received little attention. We submitted older adults and young participants to an extensive training of an ecological environment, from both route and survey perspectives. Then, we tested participants’ learning using from both route and survey perspectives. Although older adults benefit from the extensive training, they did not reach the same performance of the young participants. Despite this main effect of age, the effect of the type of learning was the same in the two groups. Congruence between type of learning and recall led to better performance in both groups. We discuss these findings in the light of cognitive models of human navigation and aging. Useful suggestions about how these findings may inform a specific cognitive intervention in older adults are also provided.     

Children and adults' distance estimations in a large-scale environment: effects of time and clutter

In two experiments adults (mean age = 19-5), sixth graders (mean age = 11-8), fourth graders (mean age = 9-8), and second graders (mean age = 7-8) walked a straight line distance through a large-scale environment. Subjects were then asked to estimate the time taken to traverse each half of the walk and to estimate the distance between objects seen along the walk. In Experiment 1 each half of the walk was traversed in the same amount of time but contained a different number of objects (clutter). Time and distance estimates were related, but were not affected by the number of intervening objects encountered between locations. In Experiment 2 subjects again encountered a different number of objects along each half of the walk but each half was traversed in varying amounts of time. Again, time and distance estimates were related, and there was no clutter effect. There were no consistent developmental differences across the two experiments. It was concluded that (1) Thorndyke's clutter effect does not occur across all types of spatial cognition tasks, and (2) children and adults tend to relate time and distance across a variety of distance estimation tasks.     

On the interdependence of temporal and spatial judgments

Three experiments are reported on the tau and kappa effects, the dependence of judgments of distance upon duration (tau) and of judgments of duration upon distance (kappa). In Experiment 1, three lights in a horizontal sequence were used to define two temporal and two spatial intervals over a total duration of 160 msec. The subject was required to choose the shorter of either the two durations or the two distances. The results confirmed Collyer’s (1977) findings that the two effects are inconsistently observed across subjects when the display duration is brief. In Experiment 2, display duration was systematically manipulated from 160 to 1,500 msec. It is argued that relative temporal judgments should become easier as the total display duration is increased and that, hence, the kappa effect should become less marked. On the other hand, relative spatial judgments should become more difficult as the total duration of the display is increased, and the tau effect should become more marked. The data were in conformity with the hypothesis. In Experiment 3, data are presented for a tau experiment which fit the assumption that the effect depends upon a weighted average of distance and the expected distance which would be traversed in the given time at constant velocity.     

Walking reduces the gap between encoding and sensorimotor alignment effects in spatial updating of described environments

Spatial updating allows people to keep track of the self-to-object relations during movement. Previous studies demonstrated that physical movement enhanced spatial updating in remote environments, but failed to find the same effect in described environments. However, these studies mainly considered rotation as a physical movement, without examining other types of movement, such as walking. We investigated how walking affects spatial updating within described environments. Using the judgement of relative directions task, we compared the effects of imagination of rotation, physical rotation, and walking on spatial updating. Spatial updating was evaluated in terms of accuracy and response times in different perspectives, and by calculating two indexes, namely the encoding and sensorimotor alignment effects. As regards response times, we found that in the imagination of rotation and physical rotation conditions the encoding alignment effect was higher than the sensorimotor alignment effect, while in the walking condition this gap disappeared. We interpreted these results in terms of an enhanced link between allocentric and sensorimotor representations, due to the information acquired through walking.     

Switching from reaching to navigation: differential cognitive strategies for spatial memory in children and adults

Navigational and reaching spaces are known to involve different cognitive strategies and brain networks, whose development in humans is still debated. In fact, high‐level spatial processing, including allocentric location encoding, is already available to very young children, but navigational strategies are not mature until late childhood. The Magic Carpet (MC) is a new electronic device translating the traditional Corsi Block‐tapping Test (CBT) to navigational space. In this study, the MC and the CBT were used to assess spatial memory for navigation and for reaching, respectively. Our hypothesis was that school‐age children would not treat MC stimuli as navigational paths, assimilating them to reaching sequences. Ninety‐one healthy children aged 6 to 11 years and 18 adults were enrolled. Overall short‐term memory performance (span) on both tests, effects of sequence geometry, and error patterns according to a new classification were studied. Span increased with age on both tests, but relatively more in navigational than in reaching space, particularly in males. Sequence geometry specifically influenced navigation, not reaching. The number of body rotations along the path affected MC performance in children more than in adults, and in women more than in men. Error patterns indicated that navigational sequences were increasingly retained as global paths across development, in contrast to separately stored reaching locations. A sequence of spatial locations can be coded as a navigational path only if a cognitive switch from a reaching mode to a navigation mode occurs. This implies the integration of egocentric and allocentric reference frames, of visual and idiothetic cues, and access to long‐term memory. This switch is not yet fulfilled at school age due to immature executive functions.     

Transition to success on the model room task: the importance of improvements in working memory

Previous work has shown that children under age 3 often perform very poorly on the model room task, in which they are asked to find a hidden toy based on its location in a scale model. One prominent theory for their failure is that they lack the ability to understand the model as both a physical object and as a symbolic representation of the larger room. A hypothesized additional component is that they need to overcome weak, competing representations of where the object was on a previous trial, and where it is in the present trial, in order to succeed in their search. Children aged 33–39 months were tested on the model room task, as well as on measures of cognitive inhibitory control, cognitive flexibility, and working memory. Results showed that performance on the model room task was not predicted by measures of inhibitory control or cognitive flexibility, but was predicted by performance on the Delayed Recognition Span Test (DRST), a measure of working memory. These findings lend support to the theory of competing representations and demonstrate the necessity of updating and maintaining strong representations in working memory to succeed in the search task.     

Caudate nucleus-dependent response strategies in a virtual navigation task are associated with lower basal cortisol and impaired episodic memory

The present research examined the relationship between endogenous glucocorticoids, navigational strategies in a virtual navigation task, and performance on standard neuropsychological assessments of memory. Healthy young adult participants (N = 66, mean age: 21.7) were tested on the 4 on 8 virtual maze (4/8 VM) and standard neuropsychological tests such as the Rey-Osterrieth Complex Figure (RO) and the Rey Auditory Verbal Learning Task (RAVLT), which measure episodic memory. The 4/8 VM differentiates between navigational strategies, where participants either use a hippocampal-dependent spatial strategy by building relationships between landmarks, or a caudate nucleus-dependent stimulus–response strategy by automatizing a pattern of open and closed arms to learn the location of objects within the maze. Degree of stress was assessed by administering the Perceived Stress Scale (PSS) questionnaire. Cortisol samples were taken on two consecutive days upon waking, 30 min after waking, at 11 am, 4 pm, and 9 pm. There was a significant difference in basal levels of cortisol between spatial and response learners. Interestingly, response learners had significantly lower cortisol levels throughout the day. The two groups did not differ in terms of perceived stress as measured with the PSS questionnaire. Moreover, there was no significant correlation between PSS scores and salivary cortisol levels, indicating that the higher cortisol levels in the spatial group were not associated with greater perceived stress. In addition, participants who spontaneously used a spatial strategy performed significantly better on the RAVLT and RO. These data indicate that the cortisol levels in the spatial group may be optimal in terms of episodic memory performance whereas the cortisol levels in the response group may be associated with poorer memory. These results are suggestive of an inverted U-shaped curve describing the effects of basal levels of circulating cortisol on memory in young adults.     

Influence of body-centered information on the transfer of spatial learning from a virtual to a real environment

This study investigated the effects of body-centred information on the transfer of spatial learning using a wayfinding task and tasks that specifically probe the route and survey strategies of navigation. The subject learned a route in either a real or a virtual environment (VE; 3D scale model of a Bordeaux neighbourhood) and then reproduced it in the real environment. The involvement of body-based information was manipulated across the spatial learning conditions in the VE: participants learned with full body-based information (treadmill with rotation), with the translational component only (treadmill without rotation) or without body-based information (joystick). In the wayfinding task, the results showed a significant effect of the learning environment with the best scores obtained in the real and treadmill with rotation conditions. There was no significant difference between these two conditions, but the real condition was significantly different from the treadmill without rotation and joystick conditions. Also, the visual flow was sufficient to successfully perform the two egocentric tasks used as well as a direction estimation task (a survey task), in so far as there is no significant difference between the joystick and the treadmill conditions. By contrast, the distance estimates were improved by the treadmill condition including the translational component (but not the rotational component). Finally, our results show that treadmill with rotation promotes the transfer of spatial learning from a virtual to a real environment (compared to joystick and treadmill without rotation). Moreover, body-centred informations are more involved in allocentric (distance estimates) than egocentric navigational strategies.     

The development and evaluation of a computer-administered measure of cognitive complexity

The present study presents and evaluates the Computer-Administered Rep Test (CART). The CART is a micro computer program that automates both the administration and scoring of a repertory grid based measure of cognitive complexity. Preliminary evaluation of the CART indicates that it provides a useful alternative to traditional paper-and-pencil administered repertory grid measures of cognitive complexity. We also examine the effect of an alternative scoring approach on the reliability of scores derived from role repertory grid measures of cognitive complexity. Results indicate that this scoring approach substantially enhances the reliability of cognitive complexity scores derived from both the paper-and-pencil and computer-administered measures.     

Underlying Spatial Skills to Support Navigation Through Large,Unconstrained Environments

Studies of spatial navigation in real‐world settings have been limited to neighborhoods, campuses, and buildings. These locations have structural components, such as roads or hallways, which may direct navigation. The current study assessed navigational skills within a large‐scale forested environment that contained few pre‐established paths. Participants were asked to find flags using only a map and compass; dependent variables included target‐finding accuracy and efficiency. In addition, measurements of sense of direction, strategy, and working memory were taken to identify how these cognitive abilities influence performance. The results demonstrate the expected correlations between sense of direction and navigational success. An unexpected correlation between spatial working memory and navigational success was also found, which was the only significant predictor of performance when all measures were regressed together. These results suggest that studies should not forget basic cognitive abilities, which may predict success more than measures of sense of direction. Copyright © 2015 John Wiley & Sons, Ltd.     

Dynamic orientation cues decrease the viewpoint cost of mental rotation

Mental rotation, as a covert simulation of motor rotation, could benefit from spatial updating of object representations. We are interested in what kind of visual cue could trigger spatial updating. Three experiments were conducted to examine the effect of dynamic and static orientation cues on mental rotation, using a sequential matching task with three-dimensional novel objects presented in different views. Experiment 1 showed that a rotating orientation cue with constant speed reduced viewpoint costs in mental rotation. Experiment 2 extended this effect with a varied-speed rotating orientation cue. However, no such benefit was observed with a static orientation cue in Experiment 3. These findings indicated that a visually continuous orientation cue is sufficient to elicit spatial updating in mental rotation. Furthermore, there may be differences in the underlying mechanisms of spatial updating on the basis of constant-speed rotating cues and varied-speed rotating cues.     

Developmental normative data for the Baron-Hopkins Board test of spatial location memory

Developmentally appropriate domain-specific tests with strong psychometric properties for preschoolers are lacking and infrequently developed. Baron’s modification of the Hopkins Board test (B-HB) to assess spatial location learning and recall in 3- and 6-year-old children has shown promise in the study of young children born prematurely. Current study data were analyzed on 172 typically developing children at age 3 years and 193 at age 6 years, born at term (≥ 37 weeks; ≥ 2500 grams). Statistically significant gender differences were found and data stratification of T-scores and percentile ranks are provided for each of the eight B-HB measures. The B-HB’s strong interrater reliability (99.5%), low-to-moderate test-retest reliability across the 3-year age span, Pearson correlations showing criterion validity, and differential functioning from other selective attention and visuospatial/visuoperceptual tests provide initial normative data for this novel measure of spatial location memory in young children.     

How divergent are children’s divergent movements? The role of cognition and expertise in a class-randomized cross-over trial

This study aimed at investigating (1) the cognitive and motor predictors of divergent movement ability (DMA) in childhood and (2) the role of sport and enriched physical education (PE) experience. Participants were 165 fifth graders, aged 10–11 years, with different histories (onset and duration) of participation in enriched PE. They were assessed in cognitive/attentional and motor/sport skills and active play/sport habits at baseline, and six months later in DMA. Results of regression analyses showed an overall prediction of DMA by sport practice and a nuanced prediction of individual DMA indices (fluency, flexibility, originality) by decision making and spatial attention ability. Linear mixed models revealed better DMA in children exposed to enriched PE, with differential effects on DMA indices depending on its duration and earlier/later onset. The results identify novel cognitive determinants of children’s DMA and suggest that sport practice and experience of designed enrichment in PE may benefit DMA.     

Environmental topography and postural control demands shape aging-associated decrements in spatial navigation performance

This study tests the hypothesis that aging-induced cognitive permeation of sensorimotor functions contributes to adult age differences in spatial navigation performance. Virtual maze-like museums were projected in front of a treadmill. Sixteen 20-30-year-old men and sixteen 60-70-year-old men performed a way-finding task in city-block or variable topographies while walking with or without support. Walking support attenuated age-related decrements in navigational learning. Navigation load increased trunk-angle variability for older adults only. Age differences in spatial knowledge persisted despite perfect place-finding performance. City-block topography was easier than variable topography for younger adults only, indicating age-related differences in reliance on spatial relational learning. Attempts at supporting older adults' navigation performance should consider sensorimotor/cognitive interactions and qualitative differences in navigational activity.     

How to separate coordinate and categorical spatial relation components in integrated spatial representations: A new methodology for analysing sketch maps

Spatial relations between landmarks can be represented by means of categories and coordinates. In the present research, this paradigm was applied to sketch maps based on information acquired in goal-directed behaviour of exploration of a university campus area. The first aim was to investigate whether categorical and coordinate information can be considered conceptually independent in sketch maps. The second aim was to assess which kind of distance measure served better to represent coordinate information in the present case study, and finally to assess the factorial structure of coordinate and categorical data. Analytic methodology as well as statistical analysis were found to confirm that separating coordinate and categorical components was formally as well as empirically appropriate. A series of confirmatory factor analyses showed the best fit for the model with two correlated components, as well as an acceptable reliability of measures emerged. The two components were moderately correlated. Moreover, the adoption of Manhattan distance seemed to be the most effective method to represent coordinate spatial relations in spatial sketch maps of areas acquired through navigation.     

Brain activation during spatial updating and attentive tracking of moving targets

Keeping aware of the locations of objects while one is moving requires the updating of spatial representations. As long as the objects are visible, attentional tracking is sufficient, but knowing where objects out of view went in relation to one's own body involves an updating of spatial working memory. Here, multiple object tracking was employed to study spatial updating and its neural correlates. In a dynamic 3D-scene, targets moved among visually indistinguishable distractors. The targets and distractors either stayed visible during continuous viewpoint changes or they turned invisible. The parametric variation of tracking load revealed load-dependent activations of the intraparietal sulcus, the superior parietal lobule, and the lateral occipital cortex in response to the attentive tracking task. Viewpoint changes with invisible objects that demanded retention and updating produced load-dependent activation only in the precuneus in line with its presumed involvement in updating spatial working memory.