慢性腰背痛患者和抑郁症患者的情绪、睡眠及疼痛症状

本研究对慢性腰背痛患者、抑郁症患者和对照人群的疼痛、抑郁水平、焦虑水平和睡眠质量进行测评,发现慢性腰背痛患者的抑郁、焦虑程度增高,失眠较常见;抑郁症患者的焦虑和失眠现象严重,疼痛是其常见症状。结果提示临床上对慢性疼痛患者和抑郁症患者的疼痛、情绪和睡眠问题予以评定和治疗具有重要意义。     

慢性失眠伴焦虑抑郁患者血清炎症相关标志物研究进展

慢性失眠是临床上常见的睡眠障碍,慢性失眠患者多伴有焦虑抑郁,慢性失眠是导致焦虑抑郁的重要危险因素,同时焦虑抑郁又会加重患者的慢性失眠,两者关系密切,相互影响,最终有可能进一步引发大脑认知功能损伤。慢性失眠和焦虑抑郁的发病机制目前尚不十分明确,最新研究提示慢性失眠伴焦虑抑郁可以导致机体内免疫机能及炎症反应的变化,现就慢性失眠伴焦虑抑郁患者血清炎症相关标志物研究进展进行综述。     

难治性与非难治性抑郁症患者自动思维的比较

目的难治性抑郁症与非难治性抑郁症病人自动思维特点之间的差异,以及自动思维与抑郁、焦虑严重程度的关系。方法采用自动思维问卷(ATQ)、汉密尔顿抑郁17项量表(HAMD)和汉密尔顿焦虑量表(HAMA)对830例抑郁症患者进行测查。结果 1常模、难治性与非难治性抑郁症患者自动思维差异具有显著性(F=658.57,p0.01)。2负性自动思维与抑郁、焦虑症状存在正相关性,与HAMD总分相关系数r=0.251(p0.01),与HAMA总分相关系数r=0.200(p0.01)3抑郁症患者负性自动思维在年龄维度上差异具有显著性(t=-3.336,p0.01)。结论1难治性与非难治性抑郁症患者自动思维均显著高于常模;难治性抑郁症与非难治性抑郁症病人自动思维差异不具有显著性。2负性自动思维与抑郁、焦虑症状存在正相关关系。3抑郁症患者负性自动思维在年龄维度上青年人自动思维出现的频度显著高于中年人。     

中国林县帕金森病患者非运动症状调查

调查中国林县PD患者非运动症状发生状况.对中国林县PD患者和对照人群进行痴呆诊断、运动功能损害评估及其他非运动症状,包括便秘、抑郁、焦虑、睡眠评估.PD患者MMSE平均分为19 (15.00～22.50)分,正常对照人群MMSE平均分21(17.25～24.00)分.两组人群时间定向和MMSE总分两组比较P＜0.05,差异有统计学意义.PD患者抑郁自评分数平均为(39.43士7.95)分,正常对照人群平均分数为(33.34±9.36)分,两组之间有显著差异(P＜0.05).PD患者焦虑患病率(43.3％),与对照人群间差异不显著.38.81％PD患者便秘,与对照组之间差异不显著.PD患者常见非运动症状,以认知功能损害、抑郁、焦虑、便秘为主要表现.     

失眠的自助式认知行为治疗元分析:疗效、影响因素及证据评价

通过元分析评估自助式失眠认知行为治疗的疗效,考察疗效影响因素,并评价证据质量。元分析共纳入35篇文献,研究发现:(1)自助式失眠认知行为治疗在治疗结束时对睡眠效率、入睡潜伏期、入睡后醒来时长、睡眠总时间、睡眠质量、抑郁和焦虑的效果量分别为0.66、-0.52、-0.47、0.20、0.34、-0.32和-0.33。(2)自助式失眠认知行为治疗与面对面失眠认知行为治疗疗效同等;自助式失眠认知行为治疗疗效显著优于最小化治疗和药物治疗。(3)共病情况与支持形式对疗效有显著影响。证据质量评价表明睡眠效率、入睡后醒来时长、睡眠总时间、抑郁和焦虑5项指标的证据质量为中等,真实值可能接近于估计值;入睡潜伏期与睡眠质量为低,真实值与估计值可能存在着差异。     

青少年早期网络欺凌/受欺凌对睡眠质量的影响：社交焦虑和抑郁情绪的链式中介作用

基于压力认知失眠模型,采用网络欺凌/受欺凌问卷、青少年社交焦虑问卷、流调中心抑郁问卷和匹兹堡睡眠质量指数问卷,对582名中小学生进行三次追踪测查,每次间隔半年,并运用结构方程模型考察社交焦虑和抑郁情绪在网络欺凌/受欺凌对睡眠质量的影响的中介作用及其性别差异。结果表明：(1)社交焦虑和抑郁情绪在网络欺凌/受欺凌影响睡眠质量的路径中均起到链式中介作用;(2)网络欺凌/受欺凌影响睡眠质量的链式中介模型存在性别差异。这启示要改善网络欺凌者与受欺凌者的睡眠质量,应关注网络欺凌给他们带来的情绪困扰,只有从根本上解决其情绪问题,才能最终有效促进其睡眠质量。     

应激干预对抑郁症患者心率变异性的影响

探讨分别以放松训练和静坐两种干预方式对抗心算对抑郁症患者心率变异性的影响 ,以及正常人、单纯抑郁症患者和伴焦虑症状的抑郁症患者在心率变异性上的差异.结果显示,静息状态下伴焦虑症状的抑郁症患者的交感神经功能亢进,兴奋性高于另外两组;放松训练可以缓解交感神经的紧张程度,并能够较静坐更好得对抗应激引起的交感神经活动增强;静坐对单纯抑郁症患者和对照组有放松作用,但引起伴焦虑症状的抑郁症患者紧张情绪.     

文拉法新治疗抑郁症及其伴发失眠和焦虑的疗效

文拉法新是一种新型的抗抑郁药,它能较强地抑制5羟色胺和去甲肾上腺素的再摄取,而消除抑郁[1],但针对文拉法新在治疗抑郁症伴发的失眠和焦虑症状的疗效方面还缺乏广泛的研究.     

原发性失眠患者的主客观睡眠特征研究

目的：了解原发性失眠患者的睡眠特点,探讨其主客观睡眠的异同点。方法：对15例原发性失眠患者、20例正常人的主观睡眠（PSQI）和客观睡眠（PSG）特点进行比较,对原发性失眠患者进行主观睡眠（PSQI）和客观睡眠（PSG）的比较。结果：原发性失眠的PSG多项指标（睡眠总时间、睡后觉醒次数、觉醒总时间、睡眠潜伏期、睡眠效率、觉睡比、睡眠维持率、REM睡眠时间和REM百分比、REM睡眠潜伏期和REM活动密度）等方面与正常对照有显著差异（p〈0.05或p〈0.01）;原发性失眠的PSQI多项指标（PSQI总分、睡眠效率、睡眠时间、睡眠潜伏期）方面与正常组对照差异显著（p〈0.01）。原发性失眠的PSQI和PSG在睡眠效率、实际睡眠时间、睡眠潜伏期方面存在显著差异（p〈0.01）。结论：原发性失眠患者的PSQI和PSG均存在一定程度的异常,原发性失眠患者有高估自己睡眠障碍的倾向。     

SLE患者焦虑抑郁影响因素调查分析

为了探讨SLE（systemic lupus erythematosus）即系统性红斑狼疮患者焦虑抑郁心理影响因素,应用Zung焦虑自评量袁（Self—rating anxiety scale,SAS）和抑郁自评量表（self—rating depression scale,SDS）,对36例系统性红斑狼疮患者进行检测,辅以自行设计因素调查表进行相关因素调查。结果显示,SDS和SAS均分为49．70±11．3和42．13±8．9,与国内常模比较,差异有统计学意义,P〈0．01。单因素分析显示：对疾病的恐惧感、对病情了解程度、治疗效果、药物副作用、家庭经济状况、家庭支持、婚姻关系、睡眠质量、担心事业受影响、躯体症状的反复出现、社交娱乐活动受限、担心医护不精心12项因素与SLE患者抑郁焦虑状态的发生显著相关,P〈0．01。证明SLE患者抑郁焦虑心理与对疾病的恐惧感、治疗效果、家庭经济状况、睡眠质量等因素相关,这为心理干预提供了依据。     

老年慢性疼痛患者疼痛接受与疼痛程度的相关关系

了解老年慢性疼痛患者疼痛接受与疼痛程度,探讨两者的相关关系.采用简易慢性疼痛接受问卷（CPAQ-8）中文版、简化McGill疼痛问卷（SF-MPQ）与一般情况调查表对335例老年疼痛患者进行调查.结果纳入有效样本308例,SF-MPQ总体平均分为（50.24±23.35）分,中文版CPAQ-8总体平均得分（21.74±5.97）分.老年慢性疼痛患者的受教育程度、疼痛期、疼痛部位及疼痛点数目等差异有统计学意义（P＜0.05）.疼痛接受与疼痛程度呈负相关（P＜0.01）,即接受程度越高者,其疼痛程度越低.     

老年癌症患者疼痛管理

面对日益加剧的人口老龄化趋势,国际肿瘤界逐渐意识到老年肿瘤治疗问题的严重性.老年肿瘤患者在被确诊时多已处于晚期,基础疾病多,各脏器功能下降,姑息治疗对老年肿瘤患者显得非常重要,尤其是疼痛治疗.目前,因为对老年人疼痛的认识不足、评估不够、过分担心药物副作用,使得老年癌痛控制现状不容乐观.本文综述了老年癌痛的特点、评估方法及治疗原则,强调对于老年癌症患者治疗的目标不是重返工作或者延长生命,而是尽最大可能地提高生活质量,让老年癌症患者远离癌痛,真正享受到无痛人生.     

老年癌症患者疼痛管理

面对日益加剧的人口老龄化趋势,国际肿瘤界逐渐意识到老年肿瘤治疗问题的严重性。老年肿瘤患者在被确诊时多已处于晚期,基础疾病多,各脏器功能下降,姑息治疗对老年肿瘤患者显得非常重要,尤其是疼痛治疗。目前,因为对老年人疼痛的认识不足、评估不够、过分担心药物副作用,使得老年癌痛控制现状不容乐观。本文综述了老年癌痛的特点、评估方法及治疗原则,强调对于老年癌症患者治疗的目标不是重返工作或者延长生命,而是尽最大可能地提高生活质量,让老年癌症患者远离癌痛,真正享受到无痛人生。     

Understanding and Treating Pain in Ethnically Diverse Patients

A revolution has taken place during the past 25 years in the understanding and treatment of chronic pain. Psychologists have contributed tremendously to this revolution. However, the primary psychological models of pain treatment have failed to adequately integrate the empirical findings and theoretical understanding of the role of ethnic factors. The goal of this paper is to address this problem by demonstrating the importance of understanding ethnic factors in treating pain, providing an overview of ethnic factors in pain, and proposing guidelines for Clinical Psychologists who treat pain patients from ethnically diverse backgrounds.     

The Accuracy of the DSM-IV Pain Disorder and the ICD-10 Persistent Somatoform Pain Disorder in Chronic Pain Patients

Objectives. In this investigation we studied the relationships between different psychological relevant subgroups and the presence of different psychosomatic symptoms in a sample of chronic pain patients, testing the accuracy of the DSM- and ICD classification systems.Results. We found no evidence for a “pure” pain syndrome according to the DSM- and ICD systems. On the contrary, we found highly significant evidence of a mixed psychosomatic condition.Conclusion. The results suggest a broad somatoform classification, with subgroups based on personality characteristics taking a stress—coping model into account, including interpersonal attachment behaviour. An alternative model of a diagnostic approach is presented.     

Psychological Flexibility,Pain Characteristics and Risk of Opioid Misuse in Noncancerous Chronic Pain Patients

Journal of Clinical Psychology in Medical Settings - Chronic pain has an estimated annual prevalence rate between 10 and 35%. In the US, first-line treatment for chronic pain is often opioids....     

Parents' Empathic Responses and Pain and Distress in Pediatric Patients

We investigated the relationship between parents' empathic responses prior to their children undergoing cancer treatment procedures and children's pain/distress during the procedures. We hypothesized: (1) parents' empathic distress would be positively associated with children's pain/distress, (2) parents' empathic concern would be negatively associated with children's pain/distress; and (3) parents' enduring dispositions and social support would be associated with their empathic responses. Parents completed: (1) measures of dispositions and perceived social support several weeks before their children underwent the procedures, and (2) state measures of empathic distress and empathic concern just before the procedures. Empathic distress was positively associated with children's pain; empathic concern was negatively associated with children's pain/distress. Predictions about dispositions and social support were also substantially confirmed.     

Quality of Life,Personality and Use of Pain Medication in Patients with Chronic Back Pain

The aim of the study was to assess whether the functional disability and the quality of life in patients with chronic back pain was associated with some personality traits and whether the use of pain medication in patients with chronic back pain can be predisposed with some personality traits. The study sample comprised 262 older patients with chronic back pain of non-inflammatory origin. The level of disability related to chronic back pain was assessed by Roland-Morris Questionnaire, health-related quality of life was assessed by Short Form 36 and personality traits by Eysenck Personality Questionnaire. Among analyzed personality traits (psychoticism, extraversion, neuroticism, lie tendencies), only neuroticism significantly predicted self-reported disability caused by back pain. Patients on pain medication had significantly worse quality of life and disability caused by back pain, but they did not differ significantly in personality traits compared to patients without pain medication. There were no differences in disability due to back pain and in level of neuroticism between patients who had jobs with higher or lower physical demand. People with higher scores on neuroticism inclined more to report a lower functional disability and the quality of life caused by chronic back pain. Patients on pain medication reported more inferior physical than psychological concept of quality of life. Use of pain medication was not associated with personality traits assessed by Eysenck Personality Questionnaire. In our elderly patients with chronic back pain, lower quality of life was associated with elevated neuroticism score and more frequent use of pain medication.