From correlates to causes: can quasi-experimental studies and statistical innovations bring us closer to identifying the causes of antisocial behavior?

Longitudinal, epidemiological studies have identified robust risk factors for youth antisocial behavior, including harsh and coercive discipline, maltreatment, smoking during pregnancy, divorce, teen parenthood, peer deviance, parental psychopathology, and social disadvantage. Nevertheless, because this literature is largely based on observational studies, it remains unclear whether these risk factors have truly causal effects. Identifying causal risk factors for antisocial behavior would be informative for intervention efforts and for studies that test whether individuals are differentially susceptible to risk exposures. In this article, we identify the challenges to causal inference posed by observational studies and describe quasi-experimental methods and statistical innovations that may move researchers beyond discussions of risk factors to allow for stronger causal inference. We then review studies that used these methods, and we evaluate whether robust risk factors identified from observational studies are likely to play a causal role in the emergence and development of youth antisocial behavior. There is evidence of causal effects for most of the risk factors we review. However, these effects are typically smaller than those reported in observational studies, suggesting that familial confounding, social selection, and misidentification might also explain some of the association between risk exposures and antisocial behavior. For some risk factors (e.g., smoking during pregnancy, parent alcohol problems), the evidence is weak that they have environmentally mediated effects on youth antisocial behavior. We discuss the implications of these findings for intervention efforts to reduce antisocial behavior and for basic research on the etiology and course of antisocial behavior.     

Male life-course persistent antisocial behavior: A review of neurodevelopmental factors

Life-course-persistent antisocial behavior, which is almost exclusively male, is arguably the single most important child clinical problem. The neurodevelopmental factors which contribute to this markedly male predominance stem from the greater male vulnerability to inherited and acquired neurodevelopmental impairments which increase the risk for antisocial behavior. The factors that contribute to this greater male vulnerability are discussed, and implications for prevention are presented.     

Neighborhood disadvantage, parent-child conflict, neighborhood peer relationships, and early antisocial behavior problem trajectories

This study examined relations among neighborhood disadvantage, parent-child conflict, deviant peer involvement in the neighborhood, and early-starting antisocial trajectories. Antisocial group patterns were identified in 218 low-income boys followed from ages 5 to 11, and neighborhood and family variables were evaluated as predictors in early and middle childhood. Four trajectory groups emerged: one increasing pattern that corresponded with developmental theories of early-starting antisocial behavior; one with initially high and decreasing problems over time; and two low antisocial groups. Parent-child conflict and neighborhood disadvantage were significantly associated with trajectory patterns, with youth in the 2 higher antisocial behavior groups characterized by more neighborhood problems and parent-child conflict than other groups. The results suggest that in early childhood, neighborhood disadvantage and family conflict place children at risk for early-starting trajectories, and that involvement with deviant peers in the neighborhood takes on an increasingly important role in patterns of antisocial behavior over middle childhood.     

Biosocial studies of antisocial and violent behavior in children and adults: a review

Despite increasing knowledge of social and biological risk factors for antisocial and violent behavior, we know surprisingly little about how these two sets of risk factors interact. This paper documents 39 empirical examples of biosocial interaction effects for antisocial behavior from the areas of genetics, psychophysiology, obstetrics, brain imaging, neuropsychology, neurology, hormones, neurotransmitters, and environmental toxins. Two main themes emerge. First, when biological and social factors are grouping variables and when antisocial behavior is the outcome, then the presence of both risk factors exponentially increases the rates of antisocial and violent behavior. Second, when social and antisocial variables are grouping variables and biological functioning is the outcome, then the social variable invariably moderates the antisocial–biology relationship such that these relationships are strongest in those from benign home backgrounds. It is argued that further biosocial research is critical for establishing a new generation of more successful intervention and prevention research.     

Neighborhood Disadvantage, Parent–Child Conflict, Neighborhood Peer Relationships, and Early Antisocial Behavior Problem Trajectories

  This study examined relations among neighborhood disadvantage, parent–child conflict, deviant peer involvement in the neighborhood, and early-starting antisocial trajectories. Antisocial group patterns were identified in 218 low-income boys followed from ages 5 to 11, and neighborhood and family variables were evaluated as predictors in early and middle childhood. Four trajectory groups emerged: one increasing pattern that corresponded with developmental theories of early-starting antisocial behavior; one with initially high and decreasing problems over time; and two low antisocial groups. Parent–child conflict and neighborhood disadvantage were significantly associated with trajectory patterns, with youth in the 2 higher antisocial behavior groups characterized by more neighborhood problems and parent–child conflict than other groups. The results suggest that in early childhood, neighborhood disadvantage and family conflict place children at risk for early-starting trajectories, and that involvement with deviant peers in the neighborhood takes on an increasingly important role in patterns of antisocial behavior over middle childhood.     

Intergenerational transmission of antisocial behavior: How do kids become antisocial adults?

Exposure to many potential environmental risk factors for child antisocial behavior is associated with one of the strongest predictors of antisocial behavior, a family history of antisociality. Because most studies of putative environmental factors do not take into account genetic propensities for antisocial behavior shared between parent and child, the possibility of genetic contributions to these “environmental” markers is typically not evaluated. In this paper, we review research on the environmental correlates of antisociality, their association with parental antisociality, and highlight findings from studies that have controlled for either genetic propensities or parental antisociality.     

The Role of Neurobiological Deficits in Childhood Antisocial Behavior

ABSTRACT— Childhood-onset antisocial behavior is an important predictor of chronic and serious forms of antisocial behavior in later life. Both biological and social factors are involved in the development of abnormal behavior. We examine the underlying role of stress-response systems in the link between early social adversity and juvenile antisocial behavior, and propose that children with genetically and/or perinatally based neurobiological deficits have problems in activating these systems and therefore experience difficulties in regulating affect and behavior. Underactivity or attenuated reactivity of the stress-response systems may predispose antisocial individuals to seek out stimulation or take risks, and thereby explain deficits in learning and socialization. Further investigations of neurobiological functioning in antisocial children might not only indicate which children are more likely to persist in behaving antisocially but also guide the development of new interventions.     

Predictive validity of the Dutch PCL:YV for institutional disruptive behavior: findings from two samples of male adolescents in a juvenile justice treatment institution

The present prospective study examined the predictive validity of the Dutch version of the Psychopathy Check List: Youth Version for disruptive behavior in male adolescents during treatment. The study comprised two samples admitted to different secure treatment institutions in The Netherlands, Jongerenhuis Harreveld (n = 81) and Rentray (n = 66). Overall, the results demonstrate that psychopathy is a significant predictor of institutional disruptive behavior, and physical violence in particular. Furthermore, Hare's traditional Factor 2 was more strongly related to disruptive incidents than Factor 1. By using the recently proposed three- and four-factor models of psychopathy, insight into the pattern of associations between psychopathy dimensions and different types of disruptive behavior was obtained. The antisocial dimension of psychopathy appeared to be more strongly related to severe incidents than the lifestyle dimension. Regression analyses identified significant contributions of the antisocial and lifestyle dimensions to the prediction of incidents. The relatively small degree of variance explained underlines the importance of other risk factors to identify adolescents at risk of disruptive behavior during institutional treatment.     

Age-of-Onset or Behavioral Sub-Types? A Prospective Comparison of Two Approaches to Characterizing the Heterogeneity within Antisocial Behavior

There are two common approaches to sub-typing the well-documented heterogeneity within antisocial behavior: age-of-onset (i.e., childhood-onset versus adolescence-onset; see Moffitt 1993) and behavioral (i.e., physical aggression versus non-aggressive rule-breaking). These approaches appear to be associated, such that aggression is more characteristic of childhood-onset antisocial behavior whereas rule-breaking is linked to both child- and adolescence-onset antisocial behavior. However, it remains unclear which approach, if either, better explains the heterogeneity within antisocial behavior. We examined this question in a prospective sample of male twins, assessed at the ages of 11, 14, 17, and 24 years. Although the age-of-onset subtypes predicted adult antisocial behavior in the expected direction when analyzed alone, this association dissipated once we controlled for aggression and rule-breaking. Such findings suggest that the behavioral sub-types of antisocial behavior may be a stronger predictor of later antisocial outcomes than is its age-of-onset.     

Risk Factors for Misconduct in a Navy Sample

Understanding antisocial behavior and organizational misconduct is an important objective, because these maladaptive behaviors are disruptive and costly to organizations and to society as a whole. The objective of this study was to identify psychosocial risk factors for misconduct and antisocial behavior in a sample of Navy personnel. A group of sailors (n = 158) who had engaged in significant misconduct were compared with a demographically similar group of sailors (n = 288) who had not engaged in misconduct and who were in good standing with the Navy. The psychosocial variables that emerged as the most important risk factors for antisocial behavior were alcohol use (odds ratio [OR] = 2.42), high impulsivity (OR = 2.20), high trait hostility (OR = 1.79), and antisocial behavior of friends (OR = 1.65). The implications of these results for the military and for research on antisocial behavior are discussed.     

The salience of the family in antisocial and delinquent behaviors among Spanish adolescents

The authors examined the relations between self-report measures of parental support, communication, and psychological control and measures of antisocial and delinquent behavior in a sample of 641 Spanish adolescents (M age = 14.35 years, SD = 1.53 years). Findings revealed similarities in the relations between parenting processes and both measures of deviant behavior. The results also demonstrated the need for researchers to consider the parenting effects of mothers and fathers independently. Specifically, maternal support was a negative predictor of antisocial and delinquent behaviors of male adolescents, and maternal psychological control was a positive predictor of antisocial and delinquent behaviors of female adolescents. Paternal parenting efforts did not account for additional variability.     

Patterns and correlates of gun ownership among nonmetropolitan and rural middle school students

Examined prevalence of gun ownership and the links among gun ownership, reasons for gun ownership, and antisocial behavior in a sample of nonmetropolitan and rural middle school students. Participants completed the Questionnaire for Students (Olweus, 1995) and included 6,263 students from 36 elementary and middle schools, of whom most were African American (range = 46%-95% per school). Reasons for gun ownership were strongly associated with rates of antisocial behavior. Youths who owned guns for sporting reasons reported rates of antisocial behavior that were only slightly higher than those reported by youths who did not own guns. Youths who owned guns to gain respect or to frighten others reported extremely high rates of antisocial behavior. These high-risk adolescent gun owners were likely to come from families of high-risk gun owners, associate with friends who were high-risk gun owners, and engage in high rates of bullying behavior. Findings suggest that effective violence prevention programs must target high-risk youths, address risk factors that go beyond individual settings, and address a comprehensive array of risk factors.     

Commentary: causal processes leading to antisocial behavior

Conceptual, and empirical, questions are raised regarding the notion that physical aggression is the main individual risk factor for antisocial behavior, that language impairment also constitutes a risk factor, the meaning of the male preponderance for antisocial behavior, the findings on environmentally mediated risk; the role of biosocial interplay; social context effects; the construct of antisocial behavior, developmental trends; processing of experiences; and transactional effects. The main blocks to using research to develop policy are the lack of evidence on (a) the mediators of the causal processes, (b) what is needed to bring about change, (c) ways to ensure that individuals who need interventions actually receive them, and (d) differences in levels of antisocial behavior.     

Influences of Biological and Adoptive Mothers’ Depression and Antisocial Behavior on Adoptees’ Early Behavior Trajectories

Research clearly demonstrates that parents pass risk for depression and antisocial behavior on to their children. However, most research confounds genetic and environmental mechanisms by studying genetically related individuals. Furthermore, most studies focus on either depression or antisocial behavior in parents or children, despite evidence of co-occurrence and shared etiology, and few consider the early origins of these problems in childhood. We estimated the influence of biological and adoptive mothers’ depression and antisocial behavior on growth in child externalizing and internalizing behaviors across early childhood using data from a prospective adoption study. Participants were 346 matched triads of physically healthy children (196 boys; 150 girls), biological mothers (BM), and adoptive mothers (AM). Latent growth curve models were estimated using AM reports of child internalizing and externalizing behaviors at ages 18, 27, and 54 months. Predictors of intercept (18 months) but not slope were identified. BM lifetime histories of major depressive disorder predicted child externalizing behaviors and BM antisocial behavior predicted child internalizing behavior. AM depressive symptoms and antisocial behavior were associated with both child outcomes. AM paths, but not BM paths were partially replicated using adopted fathers’ reports of child outcomes. BM obstetric complications, prenatal depressive symptoms, and postnatal adoptive family contact with BM did not account for BM paths. This adoption study distinguished risks conferred by biological mothers’ depression and antisocial behavior to children’s behaviors from those associated with adoptive mothers’ related symptoms. Future studies should examine gene-environment interplay to explain the emergence of serious problem trajectories in later childhood.     

The Genetic and Psychophysiological Basis of Antisocial Behavior: Implications for Counseling and Therapy

The notion that crime may have a genetic and biological basis has been resisted due to the assumption that this view necessitates a deterministic attitude to crime. This article argues that this assumption is unwarranted, and that an understanding of the genetic and psychophysiological basis of crime and antisocial behavior has important implications for counselors dealing with antisocial individuals. The interaction between genetic and environmental factors suggests that environmental changes may reduce the expression of any genetic predisposition. Psychophysiological factors interact with social factors in producing antisocial behavior, and recent psychophysiological studies have identified enhanced attentional ability in antisocial individuals that can be capitalized on by counselors in diverting clients from an antisocial way of life.     

Disruptive boys with stable and unstable high fighting behavior patterns during junior elementary school

Boys' fighting was assessed at ages six, eight, and nine. The boys (N = 69) had been selected from the 30% most disruptive children in kindergartens from low socioeconomic neighborhoods. Twenty-three percent of these disruptive boys were rated as high fighters on three assessments ("stable high fighters"), and 28% were rated as high fighters on two of the three assessments ("variable high fighters"). Forty-two percent were rated as high fighters only one out of three assessments ("occasional high fighters") and 7% were never rated as high fighters. Only high fighting in two successive years significantly increased the risk of being rated a high fighter in a following year. At age 10, stable high fighters (high fighters at ages 6, 8, 9) were perceived by teachers, peers, mothers, and the boys themselves as more disruptive and more antisocial than occasional high fighters. These results show an impressive self-other agreement in boys who have adopted a physically aggressive life style from an early age. The three groups did not differ on individual family demographic characteristics, but stable high fighters had a higher mean on an index of family socioeconomic disadvantage. Results indicate that the aggression scales which include only a few physical aggression items and many disruptive items (oppositional behavior, rejection, hyperactivity, inattention, etc.) probably aggregate two kinds of disruptive boys, the high-frequency fighters at high risk for stable disruptive, physically aggressive, and antisocial behaviors, and the disruptive low-frequency fighters who are at a lower risk of stable disruptive behavior and at a lower risk of early antisocial behavior.     

Psychosocial predictors of adult antisocial personality and adult convictions

In the Cambridge Study in Delinquent Development, 411 South London males have been followed up since age 8. This article investigates the ability of psychosocial risk factors measured at age 8 - 10 to predict antisocial personality measures at ages 18 and 32 and convictions between ages 21 and 40. The most important childhood predictors were a convicted parent, large family size, low intelligence or attainment, and child-rearing factors, including a young mother and a disrupted family. The accuracy of prediction of antisocial personality at age 32 on the basis of childhood risk factors measured more than 20 years before was surprising: nearly half of boys with a convicted parent at age 10 were antisocial at age 32, compared with one in six of the remainder. Over 60% of boys very high risk at age 8 - 10 became antisocial at age 32. While the present research shows how far adult antisocial and criminal behavior can be predicted in childhood, more research is needed to establish the precise causal mechanisms involved.     

Effects of Multiple Maternal Relationship Transitions on Offspring Antisocial Behavior in Childhood and Adolescence: A Cousin-Comparison Analysis

Previous studies of the association between multiple parental relationship transitions (i.e., when a parent begins or terminates an intimate relationship involving cohabitation) and offspring antisocial behavior have varied in their efforts to rule out confounding influences, such as parental antisocial behavior and low income. They also have been limited in the representativeness of their samples. Thus, it remains unclear to what degree parents’ multiple relationship transitions have independent effects on children’s antisocial behavior. Analyses were conducted using data on 8,652 6–9-year-old, 6,911 10–13-year-old, and 6,495 14–17-year-old offspring of a nationally representative sample of U.S. women. Cousin-comparisons were used in combination with statistical covariates to evaluate the associations between maternal relationship transitions and offspring antisocial behavior in childhood and adolescence. Cousin-comparisons suggested that associations between maternal relationship transitions and antisocial behavior in childhood and early adolescence are largely explained by confounding factors. In contrast, the associations between maternal relationship transitions and offspring delinquency in late adolescence were robust to measured and unmeasured confounds. The present findings suggest that interventions aimed at reducing exposure to parental relationship transitions or addressing the psychosocial consequences of exposure to parental relationship transitions could reduce risk for offspring delinquency in late adolescence.     

Competitive disadvantage makes attitudes towards rape less negative

Evolutionary theorists have argued that perceived competitive disadvantage may lead to more positive evaluation of, and greater likelihood of engaging in, risky and antisocial behavior. However, experimental studies have not yet examined the effects of competitive disadvantage on perceptions of rape. In the current study, we created a manipulation of perceived competitive status to test its effects on beliefs about rape. In one condition, participants were made to feel disadvantaged relative to male peers in terms of financial, physical, and intellectual power, whereas in the other condition they were made to feel advantaged. Participants were 120 heterosexual male undergraduate students. The manipulation was effective; compared to participants in the advantage condition, those in the disadvantage condition rated themselves as significantly worse off financially, shorter, in worse physical shape, and as having lower course marks than the average male student at the university. Compared to perceived competitive advantage, perceived disadvantage led to less negative attitudes towards rape. However, perceived competitive status did not significantly affect justifications and excuses for rape. Future studies using similar experimental manipulations can complement correlational studies and may contribute to greater clarity, precision, and sophistication of research and theory on the role of competitive disadvantage in rape.     

Shared and unique predictors of antisocial and substance use behavior among a nationally representative sample of South African youth

There are well-documented high prevalence rates of violence, aggression, and substance use in South Africa. We examined theoretically salient risk factors for antisocial behavior and substance use identified in high income countries (e.g., abuse and poverty; Shaw & Gross, 2008) and whether they had predictive effects among South African youth, for whom longitudinal research examining predictors of violence is lacking. We collected data from a large, high-risk longitudinal sample of youth from two provinces in South Africa, encompassing rural and urban sites (N = 3515; 97% retained at one year; 56.7% female; M age = 13.45). We assessed antisocial behavior and substance use using an adapted version of the CBCL-YSR and items from national surveys. Finally, we assessed risk factors using previously-validated indices of risk. Antisocial behavior and substance use were reciprocally related over time. Controlling for this overlap, as well as for relevant demographic covariates, child abuse predicted increases in antisocial behavior over time, and exposure to high levels of community violence predicted increases in both antisocial behavior and substance use one year later. The findings suggest that contextual risk factors underpinning etiological models of antisocial behavior and substance in high income countries are also relevant within the South African context. In particular, both harsh home and community environments were related to the development of youth antisocial and substance use behavior outcomes. We discuss the implications of these findings for preventative interventions to reduce youth engagement in risky antisocial and/or substance use behavior in South Africa.