The role of oxytocin in early mother-infant interactions: Variations in maternal affect attunement

The aim of the present research was to investigate the relationship between oxytocin and maternal affect attunement, as well as the role of affect attunement in the relationship between oxytocin and infant social engagement during early mother-infant interactions. Forty-three mother-infant dyads participated in the present study when infants were 4 months. They were observed during (1) a situation where no communication took place and (2) a natural interaction between mother and infant. During this procedure, three saliva samples from mothers and their infants were collected to determine their levels of oxytocin at different time points. Maternal affect attunement (maintaining attention, warm sensitivity) and infant interactive behaviors (gaze, positive, and negative affect) were coded during the natural interaction. Results indicated that overall maternal oxytocin functioning was negatively related to her warm sensitivity, while infant oxytocin reactivity together with maternal affect attunement were associated with infant positive social engagement with their mothers. Specifically, infant oxytocin reactivity was significantly related to their gazes at mother, but only for infants of highly attuned mothers. These results point to the complex role oxytocin plays in parent-infant interactions while emphasizing the need to analyze both overall oxytocin functioning as well as reactivity as different indices of human affiliative behavior.     

Posture and gaze in early mother–infant communication: synchronization of developmental trajectories

Weekly laboratory observations of free play for 13 middle-income mother–infant dyads, from 1 to 6 months of age, were used to study the synchronization of developmental trajectories between infant postural position and gaze direction. Mothers sat in a straight-backed chair while holding infants on their laps and were free to adjust the infant’s posture. Postural position was coded as upright (supported sitting or standing on the mother’s lap) or other (lying, cradling, or being held close to mother). Gaze was coded as either at mother’s face or away. The age of onset of visually guided reaching was also assessed. Results show that there were longer durations of gazing away when the infant was in an upright position. Over the 5 month period of observation, the dyads began with a pattern of non-upright positions accompanied by gaze at mother. Contrary to previous predictions, the developmental shift in the first 6 months from exclusive gazing at mother’s face to gazing away from mother was not synchronized with the development of reaching, but rather with changes in the infant’s posture to more upright positions. The possible role of postural position in fostering positive emotional communication is discussed.     

Robust patterns and individual variations: Stability and predictors of infant behavior in the still-face paradigm

In the present study we examined key issues regarding infant behavior in the still-face paradigm (SFP) in terms of individual variations, stability, and predictors. The sample consisted of 115 mothers and infants, with assessments at ages 3 and 6 months, including observations of maternal and infant behavior in the SFP, and parent reports of infant temperament. Both robust patterns and individual variations in infant SFP behaviors were found, with only a minority of infants showing the expected patterns for negative affect and gaze. Infant behavior patterns showed no stability from age 3 to 6 months, and infant gaze was related to more pronounced behavior changes across the SFP. Maternal sensitivity in the SFP baseline was related to some aspects of infant SFP behavior. Consistent with the differential susceptibility hypothesis, in infants with a more difficult temperament maternal sensitivity predicted a more pronounced expected pattern of changes in infant positive affect across the SFP, whereas this was not the case for infants with a more easy temperament.     

Maternal Responsiveness,Intrusiveness, and Negativity During Play with Infants: Contextual Associations and Infant Cognitive Status in A Low‐Income Sample

Maternal parenting behaviors during a mother–infant play interaction were examined in a sample of 160 low‐income mothers and their 15‐month‐old infants. Maternal responsive/didactic, intrusive, and negative behaviors were coded from videotapes and examined in relation to mothers’ age, marital status, stressful life events, and depressive symptoms, and infants’ cognitive scores at 15 and 25 months. Younger maternal age and increases in stressful life events were associated with increases in mothers’ negative behaviors whereas being married was positively associated with mothers’ responsive/didactic behaviors and inversely associated with their negative and intrusive behaviors. Mothers’ depressive symptoms were inversely associated with both responsive/didactic and intrusive behaviors and predicted lower cognitive scores in infants at 15 months, but not 25 months. Maternal responsive/didactic behaviors predicted infant cognitive scores at both ages after controlling for maternal characteristics and other parenting behaviors. Intrusiveness moderated associations between both responsive/didactic and negative parenting behaviors and infant 25‐month cognition. Maternal age, marital status, psychological resources, and contextual sources of stress play a central role in the quality of parenting among low‐income mothers, and positive mother–infant interactions are strong predictors of infants’ early cognitive status.     

Mutual regulation between infant facial affect and maternal touch in depressed and nondepressed dyads

The ability to regulate affect is important for later adaptive child development. In the first months of life, infants have limited resources for regulating their own affects (e.g. by gaze aversion), and for this reason they are dependent on external affect regulation from their parents. Previous research suggests that touch is an important means through which parents regulate their infants’ affects. Also, previous research has shown that post-partum depressed (PPD) mothers and nonclinical mothers differ in their touching behaviors when interacting with their infants. We examined the affect-regulating function of affectionate, caregiving and playful maternal touch in 24 PPD and 47 nonclinical mother-infant dyads when infants were four months old. In order to investigate the direction of effects and to account for repeated observations, the data were analysed using time-window sequential analysis and Generalized Estimating Equations. The results showed that mothers adapt their touching behaviors according to negative infant facial affect; thus, when the infant displays negative facial affect, the mothers were less likely to initiate playful touch and more likely to initiate caregiving touch. Unexpectedly, only in the PPD dyads, were the mothers more likely to initiate affectionate touch when their infants were displaying negative facial affect. Our results also showed that mothers use specific touch types to regulate infants’ negative and positive affects; infants are more likely to initiate positive affect during periods with playful touch, and more likely to terminate negative affect during periods with caregiving touch.     

Associations between mother-infant bed-sharing practices and infant affect and behavior during the still-face paradigm

Parents in the United States increasingly report bed-sharing with their infants (i.e., sleeping on a shared sleep surface), but the relationship between bed-sharing and child socioemotional outcomes are not well understood. The current study examines the links between mother-infant bed-sharing at 3 months and infant affect and behavior during a dyadic challenge task at 6 months. Further, we examine nighttime mother-infant contact at 3 months as a possible mechanism that may mediate linkages between bed-sharing and infant outcomes. Using observational data from a sample of 63 mother-infant dyads, we found that infants who bed-shared for any proportion of the observation period at 3 months displayed significantly more self-regulatory behaviors during the still-face episode of the Still-Face Paradigm (SFP) at 6 months, compared to non-bed-sharing infants. Also, infants of mothers who bed-shared for the entire observation period displayed significantly less negativity during the reunion episode than non-bed-sharing infants. There was no evidence that the relations between mother-infant bed-sharing practices and infant affect and behavior during the SFP were mediated through nighttime mother-infant contact. Results suggest that infant regulation at 6 months postpartum may vary based on early nighttime experiences, with bed-sharing potentially promoting more positive and well-regulated behavior during dyadic interaction.     

Taking stress response out of the box: stability, discontinuity, and temperament effects on HPA and SNS across social stressors in mother-infant dyads

This study investigated continuity and stability of hypothalamic-pituitary-adrenal (HPA) and sympathetic nervous system (SNS) response measures in mother-infant dyads across 2 different types of social stress sessions. Synchrony of response trajectories across systems (SNS-HPA coordination) and partners (mother-infant attunement) was addressed, as were associations with infant temperament. Primiparous mothers and their 18-month-old infants (n = 86 dyads) completed an attachment stressor--Strange Situation (Ainsworth, Blehar, Waters, & Wall, 1978)--at Session 1 and challenge stressors--cleanup task and emotion task battery--at Session 2. Mother and infant saliva samples collected to index pre-stress, stress, and post-stress response during each session were assayed for cortisol (HPA marker) and salivary alpha-amylase (sAA; SNS marker). Multilevel modeling of cortisol/sAA trajectories across sessions revealed rank-order stability in mother/infant stress measures but discontinuity in absolute levels; cortisol trajectories were higher during attachment stress, and sAA trajectories were higher during challenge stress. Varying degrees of mother-infant attunement were found across sessions/systems. Infant surgency predicted higher stress measures, and negative affect and effortful control predicted lower stress measures, though associations depended on session/system. Findings are discussed in terms of advancing a multisystemic, contextual definition of developing stress responsiveness.     

Working mother-infant interactions across the second year of life

Play interactions between 36 college-educated, middle-income, working mothers and their infants, who had attended nursery school since 1 month of age, were videotaped when the infants were 12, 18, and 24 months of age. The videotapes were coded for mother and infant looking at each other, vocalizing, affectionate play, and constructive play. Changes noted in the infants' play behaviors across this period included an increase in infant vocalizations and constructive play and a decrease in affectionate play. These results, together with corresponding decreases in the mothers' constructive and affectionate play behavior, suggest growing autonomy of the infants' play and encouragement of autonomy by the mothers. Stability of behaviors across this period and stability of relations between infant and mother behaviors were only moderate. Comparison of these data with data from a study by Clarke-Stewart and Hevey (1981) suggested greater frequency of interactive behavior among working mothers and their infants than among nonworking mothers and their infants.     

Teenage parenting in different cultures,family constellations,and caregiving environments: Effects on infant development

Teenage parenting was investigated in different ethnic groups (Cuban and American Black), family constellations (single-parent, nuclear, and extended families), and primary caregiving arrangements (mother versus other). One hundred sixty-four infants born to a representative sample of teenage mothers were observed during interactions with their mothers and were given developmental assessments when they were 12, 18, and 24 months of age. Being a Cuban mother, living in a nuclear family, and being a secondary caregiver were each associated independently with stronger social support systems and more positive child-rearing attitudes and mother-infant play interactions. Despite these early advantages, maternal stimulation and infant performance decreased over the second year of life irrespective of ethnic group, family constellation, and caregiving arrangements.     

Infant affective responses to mother's still face at 6 months differentially predict externalizing and internalizing behaviors at 18 months

This study investigated (a) stability and change in infant affective responses to the still-face interaction, (b) whether maternal depression affected infant responses, and (c) whether responses to the still-face interaction predicted toddler problem behaviors. Infants (63 girls and 66 boys) of European American mothers (67 depressed and 62 nondepressed) were observed in the still-face interaction at 2, 4, and 6 months. Affect and gaze were coded on a 1-s time base. There were stable individual differences in gazing away and in rates of negative affect. Developmental change occurred only for gazing away, which increased. At 18 months, infants who failed to smile at 6 months in the still-face interaction showed more externalizing-type behaviors than did other toddlers. Infants who failed to cry at 6 months showed fewer internalizing-type behaviors. Mothers' current depressive symptoms and infants' earlier responses to the still-face interaction made independent, comparable contributions to problem behaviors at 18 months.     

Oxytocin trajectories and social engagement in extremely premature infants during NICU hospitalization

Extremely premature infants, born 28 weeks gestation or less, are at high risk for impaired socioemotional development, due in part to exposure to early stressful social experiences that alter brain development. Understanding mediators that link experience with outcomes is necessary to assess premature infant responses to social experiences that are critical to brain development. The hormone oxytocin (OT), released during supportive interactions, has potential as a biomarker of the premature infant's responses to social experiences. The purpose of this study was to examine associations among infant plasma OT trajectories and maternal-infant social engagement behaviors during initial hospitalization. This study also examined demographic correlates of engagement behaviors in mothers and infants. Plasma from 28 extremely premature infants, born gestational ages 25–28 6/7 weeks, was collected at 14 days of life, then weekly until 34 weeks. Social engagement behaviors were measured by the Parent-Child Early Relational Assessment during a videotaped feeding when the infant was receiving one-quarter full oral feeds. Maternal-infant demographics were extracted from the medical record. Higher infant plasma OT was associated with lower infant social engagement, but no associations were found with maternal social engagement. Infant social engagement was positively related to maternal social engagement. Maternal parity was related to maternal social engagement, and infant demographics did not predict infant social engagement. The significant, yet negative, association between infant OT and engagement provides support for the measurement of OT as a neurobiological antecedent to infant social behaviors. Finally, this research suggests that during the earliest period of infant socio-behavioral development, premature infants are behaviorally reactive to the social engagement behaviors of their mothers.     

Parent mind-mindedness,sensitivity, and infant affect: Implications for attachment with mothers and fathers

Previous research examining links between parenting and attachment has focused on behavioral aspects of parenting such as sensitivity. However, by assessing how parents reflect on infants’ mental states (mind-mindedness) we gain a broader understanding of parenting and how it impacts attachment. Mothers, fathers, and their infants (N = 135) participated in the Still Face Paradigm (SFP) at 3-, 5-, and 7- months of age, and the Strange Situation with mothers at 12 months and fathers at 14 months. Parent sensitivity and infant affect were coded from the SFP and all videos were transcribed and later coded for parents’ use of appropriate and non-attuned mind-mindedness toward their infants. Attachment with each parent was coded from the Strange Situation. Mixed effects models examined trajectories of parents’ mind-mindedness in relation to parent sensitivity and infant affect across attachment groups. Significant differences between parent gender and attachment category were detected. Specifically, parents who were less sensitive were also less mind-minded toward insecure-avoidant infants; parents used more non-attuned mind-mindedness when infants had higher negative affect. Findings suggest that, in addition to parent sensitivity, parents’ use of appropriate and non-attuned mind-mindedness during a parent-infant interaction provides insight into the developing attachment relationship for mothers and fathers.     

Individual differences in non-clinical maternal depression impact infant affect and behavior during the still-face paradigm across the first year

Maternal depression can significantly impact mothers’ sensitivity to their infants’ needs as well as infants’ social and emotional development. The still-face paradigm (SFP) is widely used to assess infants’ understanding of the contingency between their own behavior and that of their caregivers, as well as infants’ ability to self-regulate arousal levels during sudden changes in maternal responsiveness. Infants of clinically depressed mothers display blunted levels of negative affect compared to infants of non-depressed mothers during the still-face (SF) phase. However, little is known about whether individual differences in elevated, non-clinical levels of maternal depression similarly affect mother-infant interactions. The current study examines the longitudinal effects of non-clinical maternal depression on infant and maternal behaviors during the SFP. Infants (N = 63) were assessed at 5 and 9 months and maternal depression was assessed at 5 months using the Beck Depression Inventory (BDI). Infants of mothers with elevated levels of depression displayed less negative engagement during the SF phase compared to infants of mothers with lower levels of depression. This effect was present at 5 months, but not at 9 months. Findings demonstrate that non-clinical levels of maternal depressive symptomatology can have a significant impact on infants’ affective regulation during the first half of the first year of life, but this does not necessarily have a long-lasting influence later in infancy. Interventions may want to target mothers with non-clinical depression to promote healthy infant social and emotional development.     

Examining pathways linking maternal depressive symptoms in infancy to children’s behavior problems: The role of maternal unresponsiveness and negative behaviors

The extent to which maternal depressive symptoms in the first 6 months of life is linked with internalizing and externalizing behaviors in childhood through specific insensitive maternal behaviors (unresponsive and overtly negative behaviors) was examined in a sample of 259 mother-infant dyads. In addition, the extent to which these paths were moderated by infant negative emotionality was also examined. Maternal depressive symptoms were assessed prenatally and when infants were 6 months and 2 years old. Maternal unresponsive and overtly negative behaviors and infant negative emotionality were observed when infants were 6 months old. Mothers reported on infant’s internalizing and externalizing behaviors when infants were 2 years old. Maternal depressive symptoms were directly associated with higher internalizing behaviors; this path was not mediated by maternal behaviors. Depressive symptoms were unrelated to externalizing symptoms. Infant negative emotionality did not moderate these effects, but was related positively to overtly negative maternal behaviors, and temperament interacted with maternal depressive symptoms to predict unresponsive maternal behaviors. Results suggest that early maternal depressive symptoms, infant negative emotionality, and negative maternal behavior pose risk for infants’ later internalizing behaviors, but the proposed moderated mediation model was not supported.     

Cortisol reactivity and negative affect among preterm infants at 12 months during a mother-infant interaction task

The purpose of this study was to investigate correlates of preterm (PT) infant’s cortisol reactivity and the association to infant negative affect, during a mother-infant interaction procedure. Participants included 48 infants born prematurely (gestational age < 37 weeks) and their mothers, assessed when infants were 12 months old corrected for prematurity. The examined variables comprised both neonatal and environmental dimensions including maternal interactive behavior. Infant negative affect and maternal interactive behavior were assessed with a standardized mother-infant interaction task. A baseline infant saliva sample was collected before the interaction began, and a second sample after the interaction episodes ended. Results revealed that decrease of infant’s cortisol concentration was significantly associated with the exposure to more sensitive, and less intrusive maternal behaviors. However, once controlled for neonatal risk, family SES and maternal psychological distress, the associations were rendered non-significant. Although the association between cortisol reactivity and negative affect trended toward significance, maternal intrusiveness was the only significant predictor of observed infant negative affect. Findings suggest the importance of primary relational experiences on PT infants' early regulatory competencies.     

Differential attachment responses of male and female infants to frightening maternal behavior: Tend or befriend versus fight or flight?

Taylor and colleagues (2000) proposed that males tend to display fight or flight responses to threat while females are more likely to display affiliative "tend or befriend" responses. In light of this hypothesis, gender differences in infant attachment behaviors were examined in a sample of 65 low-income mother-infant dyads, half of whom were referred to a home-based intervention service because of concerns about the quality of caregiving. Attachment behaviors were assessed in the Ainsworth Strange Situation when infants were 18 months old, and maternal behaviors were coded both for frightened or frightening behaviors, using the Main and Hesse (1992) coding inventory, and for disrupted affective communication using the Atypical Maternal Behavior Instrument for Assessment and Classification assessment tool (AMBIANCE; Lyons-Ruth, Bronfman, & Parsons, 1999). Results indicated that as maternal behavior became more frightening, female infants tended to approach their mothers more than male infants. These gender differences in response to maternal frightening behavior also were evident in the clinically referred subsample. The results suggest that gender-based differences in tendencies to show affiliative behaviors to threat may complicate interpretation of attachment behavior in clinical contexts.     

Face-to-face interaction behavior across early infancy

Stability and change in mother-infant interaction behavior were assessed across early infancy. At 8 versus 4 months, the infants showed more smiling, vocalizing and motor-activity, and their mothers touched and moved their infants' limbs less often. Stability was noted only for infant distress-brow and mother's touching the infant. Although very few relationships were apparent between mother and infant behavior at 4 months, several maternal behaviors at 4 months were related to infant behaviors at 8 months, and several relationships were noted between maternal and infant behavior at 8 months.     

Digital disruption? Maternal mobile device use is related to infant social‐emotional functioning

Mobile device use has become increasingly prevalent, yet its impact on infant development remains largely unknown. When parents use mobile devices in front of infants, the parent is physically present but most likely distracted and unresponsive. Research using the classic Still Face Paradigm (SFP) suggests that parental withdrawal and unresponsiveness may have negative consequences for children's social‐emotional development. In the present study, 50 infants aged 7.20 to 23.60 months (M = 15.40, SD = 4.74) and their mothers completed a modified SFP. The SFP consisted of three phases: free play (FP; parent and infant play and interact), still face (SF; parent withdraws attention and becomes unresponsive), and reunion (RU; parent resumes normal interaction). The modified SFP incorporated mobile device use in the SF phase. Parents reported on their typical mobile device use and infant temperament. Consistent with the standard SFP, infants showed more negative affect and less positive affect during SF versus FP. Infants also showed more toy engagement and more engagement with mother during FP versus SF and RU. Infants showed the most social bids during SF and more room exploration in SF than RU. More frequent reported mobile device use was associated with less room exploration and positive affect during SF, and less recovery (i.e., engagement with mother, room exploration positive affect) during RU, even when controlling for individual differences in temperament. Findings suggest that the SFP represents a promising theoretical framework for understanding the impact of parent's mobile device use on infant social‐emotional functioning and parent–infant interactions.     

Maternal mind-mindedness over infants’ first three months

Maternal mind-mindedness refers to mothers’ ability to reflect upon their infants’ mental states and respond appropriately. The present study assessed mind-mindedness longitudinally from the newborn period to the infant age of three months. The study is the first to assess maternal mind-mindedness in the infant’s early life prior to three months (one week, one month, two months, three months). To measure maternal mind-mindedness, mothers’ speech to their infants is coded for mental state comments about the infants’ thoughts, desires, and emotions. Appropriate mind-minded comments are judged to accurately reflect the infants’ mental states; non-attuned mind-minded comments are judged to misinterpret the infants’ mental states. Mothers’ individual stability (rank order stability) and group level continuity (mean level of stability across the infant ages) were assessed. Mothers showed modest temporal stability in both appropriate and non-attuned mind-mindedness over the infants’ first three months. The continuity of mind-mindedness showed that appropriate mind-mindedness increased over the infant ages, but non-attuned mind-mindedness showed no change. In infants’ early lives, mothers’ ability to accurately interpret their infants’ mental states is enhanced as the mother-infant relationship develops and infants become more communicative partners.     

Coding infant engagement in the Face-to-Face Still-Face paradigm using deep neural networks

BackgroundThe Face-to-Face Still-Face (FFSF) task is a validated and commonly used observational measure of mother-infant socio-emotional interactions. With the ascendence of deep learning-based facial emotion recognition, it is possible that common complex tasks, such as the coding of FFSF videos, could be coded with a high degree of accuracy by deep neural networks (DNNs). The primary objective of this study was to test the accuracy of four DNN image classification models against the coding of infant engagement conducted by two trained independent manual raters.Methods68 mother-infant dyads completed the FFSF task at three timepoints. Two trained independent raters undertook second-by-second manual coding of infant engagement into one of four classes: 1) positive affect, 2) neutral affect, 3) object/environment engagement, and 4) negative affect.ResultsTraining four different DNN models on 40,000 images, we achieved a maximum accuracy of 99.5% on image classification of infant frames taken from recordings of the FFSF task with a maximum inter-rater reliability (Cohen's κ-value) of 0.993.LimitationsThis study inherits all sampling and experimental limitations of the original study from which the data was taken, namely a relatively small and primarily White sample.ConclusionsBased on the extremely high classification accuracy, these findings suggest that DNNs could be used to code infant engagement in FFSF recordings. DNN image classification models may also have the potential to improve the efficiency of coding all observational tasks with applications across multiple fields of human behavior research.