自我意识情绪:聚焦于自我的道德情绪研究

自我意识情绪是人们在社会交往中根据一定的价值标准评价自我或被他人评价时产生的情绪,也是个体根据道德自我认同标准,比较不同情境下的行为或行为倾向时产生的道德情绪。自我意识情绪以自我认知为基础,具有独特性。其中,内疚、羞耻、尴尬以及自豪和道德行为之间存在着千丝万缕的联系,并且有反馈、激发动机以及协调人际行为等道德功能。因此极有必要开展自我意识情绪的本土化研究,为建设和谐社会提供理论支持和实验根据。     

关于益生菌与炎症性肠病

炎症性肠病是一类病因和发病机制尚不完全明确的肠道慢性非特异性炎症性疾病,其发病涉及多种因素的共同作用。目前的治疗包括传统治疗和新兴的生物治疗,本文主要就益生菌与炎症性肠病作一浅显的探讨。     

People Living with Inflammatory Bowel Disease Want Multidisciplinary Healthcare: A Qualitative Content Analysis

This study reports on the preferences of people with inflammatory bowel disease (IBD) for their healthcare. Overall, 477 people with IBD responded to an open-ended survey question within a larger study. We qualitatively content-analysed these responses with open coding using NVivo. Respondents expressed a desire for (1) better communication, (2) multidisciplinary care, (3) better treatment, services and specialist care, (4) whole person care, (5) health promotion, (6) proactive healthcare, (7) fewer administrative issues and (8) improved hospital experience. Patients with IBD want patient-centred, multidisciplinary care. Healthcare professionals should facilitate patients’ access to proactive care.

     

炎症性肠病的基因学诊断

炎症性肠病（IBD）是一种涉及多基因的复杂疾病,传统的IBD的诊断方法是依靠病史和临床表现、结肠镜检、钡剂灌肠、病理检查及实验室检查等综合性诊断,但难以满足病因学及亚型分类,随着IBD易感基因的发现,采用血清免疫学和基因标志物来诊断和鉴别IBD与其他疾病以及评估临床病程及预后等成为可能。现将IBD易感基因以及临床应用作一综述。     

干细胞移植治疗炎症性肠病的进展

我国炎症性肠病(IBD)发病率逐年上升.近年来的研究发现干细胞移植对于炎症性肠病尤其是难治病例的治疗有效,故本文对既往干细胞移植治疗IBD的基础和临床研究进行回顾,总结干细胞移植对于炎症性肠病治疗的研究进展.     

炎症性肠病的临床治疗新进展

炎症性肠病是一种累及胃肠道的慢性疾病,目前主要治疗药物如氨基水杨酸制剂和免疫抑制剂均有一定的局限性.英夫利昔等多种生物制剂的使用,临床已取得可靠疗效,为患者带来更多治疗机会.随着对炎症性肠病发病机制认识的不断深入,针对免疫功能异常的新的治疗手段也越来越被人们所接受和使用,本文就目前IBD的生物免疫治疗进展做一综述.     

肠内外营养对炎症性肠病的治疗价值

炎症性肠病是一种病程长且反复的疾病,它的发病可能与环境、免疫、肠道微生态与基因有关.由于摄入减少、消化吸收不良、丢失增加、能量-蛋白质改变和药物作用等各种原因,炎症性肠病患者不管在急性期还是缓解期常常出现营养不良.然而,营养不良又妨碍炎症性肠病治疗的效果,所以肠内外营养对炎症性肠病的治疗就显得至关重要.本文归纳了肠内外营养治疗的价值及成分改良对治疗价值影响的主要进展,最后在此基础上,为了使得营养治疗更有针对性,本文对炎症性肠病患者的营养遗传学及营养基因组学研究提出了展望.     

健康者肠道细菌移植治疗炎症性肠病的应用前景

炎症性肠病(inflammatory bowel disease,IBD)包括克罗恩病(Crohn's disease,CD)和溃疡性结肠炎(ulcerative colitis,UC),其病因和发病机制目前尚不清楚,近来研究显示肠道细菌参与IBD的发生.本文针对肠道菌群与IBD发病的相关性,以及肠道细菌移植在肠道疾病及代谢性疾病中的应用,探讨肠道细菌移植治疗IBD的应用前景.     

炎症性肠病的药物治疗现状及进展

炎症性肠病（IBD）病程迁延反复,影响患者生活质量,耗费卫生资源。虽然传统药物如5-氨基水杨酸、糖皮质激素、免疫抑制剂等仍是目前治疗主流,但是大量有关发病机制的研究以及循证医学的发展对IBD的治疗产生了积极的推进作用。IBD的治疗正步入免疫调节的生物学时代,多种新型生物制剂的出现为IBD的治疗提供了新的策略和选择。现就目前IBD药物治疗现状以及最新进展进行综述,以期对临床IBD治疗提供参考。     

The Complexity and Challenges of Genetic Counseling and Testing for Inflammatory Bowel Disease

Inflammatory bowel disease (IBD) is an umbrella term referring to two chronic idiopathic intestinal diseases: ulcerative colitis (UC) and Crohn’s disease (CD). Both UC and CD are characterized by immune activation that leads to symptoms, but the location, severity and behavior of the inflammation varies among individuals and in characteristic ways between UC and CD. A majority of patients with IBD are diagnosed in young adulthood, but the response to therapy is variable and difficult to predict, with some patients demonstrating a prompt and effective remission while others have continuous symptoms that do not respond to existing medical options. Surgery remains a frequent and necessary occurrence among patients with IBD, but in UC it is considered curative, while in CD only temporizing. Clinical observations, epidemiological studies, and molecular genetics have provided strong evidence that both genetic and environmental factors are important determinants for disease susceptibility. In recent years, a number of genes have been identified that associate with CD and UC, although the clinical utility of these discoveries in patients or in susceptible family members has not been determined. Nonetheless, it is hoped that these fundamental advances in our understanding of IBD will lead to better therapies for patients and prevention strategies for those who are susceptible. Effective incorporation of clinical genetic testing for IBD into practice will require appropriate education and counseling.     

Mechanisms of Quality of Life and Social Support in Inflammatory Bowel Disease

Cognitive and social factors are essential considerations in inflammatory bowel disease (IBD) patient management, but existing research is limited. This study aims to expand the IBD literature by examining the relationship between social supports and QoL, while examining mechanisms in these relationships. Consenting patients attending an IBD outpatient clinic were provided a survey package (N = 164). Regressions evaluated predictors of IBD-QoL, and catastrophizing and optimism were examined as mediators between social support and IBD-QoL. Diminished IBD-QoL was predicted by younger age, greater negative spousal responses, and less perceived spousal support. Mediation models showed helplessness catastrophizing to be the lone mediator, acting as a mechanism between both negative spousal responses and perceived spousal support with IBD-QoL. Social interaction variables are associated with IBD-QoL, but patients’ experience of helplessness acts to reduce their ability to benefit from social support. Patient care should consider supportive social and cognitive factors to improve IBD-QoL.     

Patient Perspectives on Medical Trauma Related to Inflammatory Bowel Disease

Journal of Clinical Psychology in Medical Settings - Post-traumatic stress symptoms (PTSS) in response to medical trauma are understudied in inflammatory bowel disease (IBD). Two studies identify...     

Gender Differences in the Social Functioning of Adolescents with Inflammatory Bowel Disease

Inflammatory bowel disease (IBD) has been associated with social difficulties. Boys with IBD may have increased risk for social problems due to delayed growth and puberty, but gender differences in social functioning have not been investigated. This study examined gender differences in multiple areas of social functioning for adolescents with IBD compared to healthy adolescents. Participants were 92 adolescents 11-17?years (50 with IBD, 42 healthy) and parents who completed questionnaires assessing social functioning. IBD was associated with poorer social functioning in the areas of social competence and social problems. Boys with IBD had worse social competence, with no gender differences for social problems. Gender predicted the use of social contact as a coping strategy, but no significant group differences were found for other areas of social functioning. Adolescents with IBD experience significant social difficulties in some areas, and boys are at risk for poor social competence. However, previously reported social difficulties may not extend to all areas of social functioning.     

A Thematic Analysis of Men's Experience With a Partner's Elective Abortion

Research concerning men's experience with a partner's abortion is limited. To foster understanding of this topic, the authors used online surveys to gather data from men whose partners underwent induced abortion. A thematic analysis of men's comments about their experience revealed 3 salient themes: loss and grief, helplessness and/or victimization, and spiritual healing. Findings are discussed in terms of future research and counseling practices as they relate to pregnancy outcome decisions.     

On the Link between Perceived Parental Rearing Behaviors and Self-conscious Emotions in Adolescents

This study examined relationships between the self-conscious emotions of guilt and shame in both clinical (N?=?104) and non-clinical (N?=?477) (young) adolescents aged 11–18?years, who completed a questionnaire to assess perceived parental rearing behaviors (EMBU-C) and a scenario-based instrument to measure proneness to guilt and shame (SCEMAS). Results indicated that parental rearing dimensions were positively related to self-conscious emotions. Regarding the non-clinical sample, both favourable (emotional warmth) and unfavourable (rejection) paternal and maternal rearing dimensions were significant correlates of guilt- and shame-proneness. The results for the clinical sample were less conclusive: only maternal emotional warmth and rejection were found to be significantly associated with guilt and shame. Interestingly, no associations between any of the paternal rearing dimensions and self-conscious emotions emerged. Taken together, these results are in keeping with the notion that parental rearing factors are involved in the development of both adaptive and maladaptive self-conscious emotions in adolescents.     

Age and Body Satisfaction Predict Diet Adherence in Adolescents with Inflammatory Bowel Disease

The aim of the current study was to determine whether age and body satisfaction predict dietary adherence in adolescents with Inflammatory Bowel Disease (IBD), and whether older females are less adherent than younger males and females. Forty-four participants aged 10–21 with IBD were recruited. Participants provided informed consent and demographics. Body satisfaction was measured by a questionnaire and a task in which participants selected their current and ideal body image out of silhouettes depicting bodies ranging from underweight to obese. Adherence was measured by marking a 100 mm visual analog scale, the 1-week completion of a dietary log, and a questionnaire evaluating coping strategies used for overcoming obstacles to dietary adherence. Age was related to dietary adherence, with younger children being more likely to adhere. Participants more satisfied with their body reported better dietary adherence. Findings remained consistent across multiple measures of body satisfaction and adherence. Healthcare providers and parents should be informed of these findings in order to improve adherence.     

Resilience Factors in Paediatric Inflammatory Bowel Disease: Health Care Provider,Parent and Youth Perspectives

Journal of Child and Family Studies - Exploring factors related to resilience in youth with inflammatory bowel disease may elucidate modifiable risk factors and inform interventions. Yet, how...     

The Contributions of Child Behavioral Functioning and Parent Distress to Family Functioning in Pediatric Inflammatory Bowel Disease

The objective of this study was to examine the relative contributions of both parental and adolescent functioning to family functioning in adolescent patients with inflammatory bowel disease (IBD) and their families. Participants were 45 adolescents (27 male, 18 female) 13-17?years old (M?=?15.41?years, SD?=?1.32) with IBD and their parents. Families completed measures of patient behavioral functioning and depression, parent distress and family functioning. Disease severity assessments were completed via data provided by patients' gastroenterologists. Results indicated that parent-reported patient behavioral problems accounted for a significant 26% of variance in family functioning. Post-hoc analysis revealed that externalizing behavior problems accounted for the majority of this variance compared to internalizing behavior problems. These results suggest that externalizing problems may have a more significant impact on these families than previous research indicates. Moreover, externalizing behaviors may significantly impact family adaptation and should be taken into consideration during routine clinical care. Further research is needed to replicate and expand upon these findings.     

The Semantics of Time and Space: A Thematic Analysis

Three empirical studies and one analysis of pre-existing data were performed to determine the everyday meanings of time, a major component of phenomenological analyses of human experience. To this end, participants in Studies 1 and 2 sorted time related words into groups having similar meanings, with these groups then evaluated by hierarchical clustering procedures. Results of Studies 1 and 2 produced similar clustering patterns suggesting it was possible to define the everyday meanings of time in terms of experiences of change and continuity, linear organization, tempo, and boundaries. Results of Study 3 indicated little or no effect on clustering patterns of time words when space words also were included in the set of items to be sorted. Concerns about the size and representativeness of the words used as stimuli in Studies 1, 2 and 3 led to an analysis of over 2,000 words falling under the general heading of Time in Roget’s Thesaurus. Results of this analysis revealed that clusters comparable to those obtained in the other three studies also appeared in these data. These results were discussed in terms of their implications for the way in which “invisible” concepts such as time are thought about and used, particularly as related to figurative expression.