Selective attention to emotional faces following recovery from depression

This study was designed to examine attentional biases in the processing of emotional faces in currently and formerly depressed participants and healthy controls. Using a dot-probe task, the authors presented faces expressing happy or sad emotions paired with emotionally neutral faces. Whereas both currently and formerly depressed participants selectively attended to the sad faces, the control participants selectively avoided the sad faces and oriented toward the happy faces, a positive bias that was not observed for either of the depressed groups. These results indicate that attentional biases in the processing of emotional faces are evident even after individuals have recovered from a depressive episode. Implications of these findings for understanding the roles of cognitive and interpersonal functioning in depression are discussed.     

Gaze behavior predicts memory bias for angry facial expressions in stable dysphoria

Interpersonal theories suggest that depressed individuals are sensitive to signs of interpersonal rejection, such as angry facial expressions. The present study examined memory bias for happy, sad, angry, and neutral facial expressions in stably dysphoric and stably nondysphoric young adults. Participants' gaze behavior (i.e., fixation duration, number of fixations, and distance between fixations) while viewing these facial expressions was also assessed. Using signal detection analyses, the dysphoric group had better accuracy on a surprise recognition task for angry faces than the nondysphoric group. Further, mediation analyses indicated that greater breadth of attentional focus (i.e., distance between fixations) accounted for enhanced recall of angry faces among the dysphoric group. There were no differences between dysphoria groups in gaze behavior or memory for sad, happy, or neutral facial expressions. Findings from this study identify a specific cognitive mechanism (i.e., breadth of attentional focus) that accounts for biased recall of angry facial expressions in dysphoria. This work also highlights the potential for integrating cognitive and interpersonal theories of depression.     

Attentional Processing of Threat in Bipolar Disorder: Going Beyond Mood-Congruency

Emotional processing in bipolar disorder (BD) entails a complex attentional pattern not merely restricted to happy or sad biases, but also directed towards threatening information. This study examined threat-related bias on attentional orienting when participants were not instructed about the presentation of emotional stimuli (i.e., implicit instructions). An emotional dot-probe task in which an emotional face (i.e., threat, sad, happy) is simultaneously displayed with a neutral face was applied to BD individuals in their different episodes: mania (n?=?26), depression (n?=?24), and euthymia (n?=?28) as well as to a group of healthy controls (n?=?28). Symptomatic BD patients (i.e., in a manic or depressive episode) showed an attentional orienting bias toward threatening faces but not for happy or sad faces, while euthymic BD patients did not exhibit any attentional bias for emotional stimuli. A bias toward happy faces was found in the control group. Threat-related bias was not related to the severity of affective and anxiety symptoms in BD. When attention is not explicitly directed to emotional information, threat-related bias may characterize attentional orienting during mania and depression, but may be attenuated during euthymia.

     

抑郁个体对情绪面孔的返回抑制能力不足

探讨抑郁对情绪面孔返回抑制能力的影响。以贝克抑郁量表、自评抑郁量表、CCMD-3和汉密顿抑郁量表为工具筛选出了正常对照组、抑郁康复组和抑郁患者组各17名被试进行了真人情绪面孔线索-靶子任务的行为学实验和事件相关电位(ERP)实验。在线索靶子范式中, 靶子在线索消失后出现, 被试对靶子的位置作出反应。行为学实验显示线索靶子间隔时间(stimulus onset asynchronies, SOA)为14ms时, 正常对照组对中性面孔有返回抑制效应, 抑郁康复组对所有面孔均存在返回抑制效应, 患者组对愤怒、悲伤面孔和中性面孔存在返回抑制效应; SOA为250ms时三组被试均对悲伤面孔存在返回抑制能力不足, 以患者组最突出, 康复组对高兴面孔存在返回抑制能力不足; SOA为750ms时正常组对悲伤面孔存在返回抑制效应, 康复组对高兴和悲伤面孔存在返回抑制能力不足, 患者组对悲伤面孔存在返回抑制能力不足, 对愤怒面孔存在返回抑制效应。在SOA为750ms的条件下, ERP波形特点为正常组对高兴面孔线索P3波幅大于其他组, 对高兴面孔无效提示P1波幅小于其他面孔, 对悲伤面孔有效提示P1波幅小于高兴面孔, 对高兴面孔有效提示P3波幅大于患者组, 对悲伤面孔无效提示P3波幅大于其他组; 康复组对悲伤面孔线索P3波幅大于其他面孔, 对高兴面孔有效提示P3波幅大于患者组, 对悲伤面孔无效提示P3波幅小于正常组; 患者组对悲伤面孔线索P1波幅大于其他组、P3波幅大于其他面孔, 对悲伤面孔无效提示P3波幅小于正常组, 高兴面孔有效提示P3波幅小于其他组。提示抑郁患者对负性刺激有返回抑制能力不足, 这种对负性刺激抑制能力的缺失导致抑郁个体难以抗拒负性事件的干扰而受到不良情绪状态的困扰, 所以他们可能更多的体验到抑郁情绪, 并致使抑郁持续和发展。而抑郁康复个体对高兴、悲伤面孔均有返回抑制能力不足, 这让康复个体能同时感受到正、负性刺激, 从而能保持一种认知和情绪上特定的平衡。     

Understanding associations between negatively biased attention and depression and social anxiety: positively biased attention is key

ABSTRACT

Background and objectives: Although research supports the premise that depressed and socially anxious individuals direct attention preferentially toward negative emotional cues, little is known about how attention to positive emotional cues might modulate this negative attention bias risk process. The purpose of this study was to determine if associations between attention biases to sad and angry faces and depression and social anxiety symptoms, respectively, would be strongest in individuals who also show biased attention away from happy faces.

Methods: Young adults (N?=?151; 79% female; M?=?19.63 years) completed self-report measures of depression and social anxiety symptoms and a dot probe task to assess attention biases to happy, sad, and angry facial expressions.

Results: Attention bias to happy faces moderated associations between attention to negatively valenced faces and psychopathology symptoms. However, attention bias toward sad faces was positively and significantly related to depression symptoms only for individuals who also selectively attended toward happy faces. Similarly, attention bias toward angry faces was positively and significantly associated with social anxiety symptoms only for individuals who also selectively attended toward happy faces.

Conclusions: These findings suggest that individuals with high levels of depression or social anxiety symptoms attend preferentially to emotional stimuli across valences.     

The threat of appearing prejudiced and race-based attentional biases

The current work tested whether external motivation to respond without prejudice toward Blacks is associated with biased patterns of selective attention that reflect a threat response to Black individuals. In a dot-probe attentional bias paradigm, White participants with low and high external motivation to respond without prejudice toward Blacks (i.e., low-EM and high-EM individuals, respectively) were presented with pairs of White and Black male faces that bore either neutral or happy facial expressions; on each trial, the faces were displayed for either 30 ms or 450 ms. The findings were consistent with those of previous research on threat and attention: High-EM participants revealed an attentional bias toward neutral Black faces presented for 30 ms, but an attentional bias away from neutral Black faces presented for 450 ms. These attentional biases were eliminated, however, when the faces displayed happy expressions. These findings suggest that high levels of external motivation to avoid prejudice result in anxious arousal in response to Black individuals, and that this response affects even basic attentional processes.     

Attentional Biases for Emotional Faces in Young Children of Mothers with Chronic or Recurrent Depression

Attentional biases for negative stimuli have been observed in school-age and adolescent children of depressed mothers and may reflect a vulnerability to depression. The direction of these biases and whether they can be identified in early childhood remains unclear. The current study examined attentional biases in 5–7-year-old children of depressed and non-depressed mothers. Following a mood induction, children participated in a dot-probe task assessing biases for sad and happy faces. There was a significant interaction of group and sex: daughters of depressed mothers attended selectively to sad faces, while children of controls and sons of depressed mothers did not exhibit biases. No effects were found for happy stimuli. These findings suggest that attentional biases are discernible in early childhood and may be vulnerability markers for depression. The results also raise the possibility that sex differences in cognitive biases are evident before the emergence of sex differences in the prevalence of depression.     

Children's 5-HTTLPR genotype moderates the link between maternal criticism and attentional biases specifically for facial displays of anger

Theorists have proposed that negative experiences in childhood may contribute to the development of experience-specific information-processing biases, including attentional biases. There are also clear genetic influences on cognitive processes, with evidence that polymorphisms in specific candidate genes may moderate the impact of environmental stress on attentional biases (e.g., a functional polymorphism in the serotonin transporter gene; 5-HTTLPR). In the current study, we tested a gene×environment (G×E) model of risk for attentional biases. We hypothesised that children whose mothers exhibit high levels of expressed emotion criticism (EE-Crit) would display attentional biases specifically for angry, but not happy or sad, faces, and that this link would be stronger among children carrying one or two copies of the 5-HTTLPR short allele than among those homozygous for the long allele. Results generally supported these hypotheses, though we found that carriers of the 5-HTTLPR short allele who also had a critical mother exhibited attentional avoidance of angry faces rather than preferential attention.     

Short-term memory for emotional faces in dysphoria

The study aimed to determine if the memory bias for negative faces previously demonstrated in depression and dysphoria generalises from long- to short-term memory. A total of 29 dysphoric (DP) and 22 non-dysphoric (ND) participants were presented with a series of faces and asked to identify the emotion portrayed (happiness, sadness, anger, or neutral affect). Following a delay, four faces were presented (the original plus three distractors) and participants were asked to identify the target face. Half of the trials assessed memory for facial emotion, and the remaining trials examined memory for facial identity. At encoding, no group differences were apparent. At memory testing, relative to ND participants, DP participants exhibited impaired memory for all types of facial emotion and for facial identity when the faces featured happiness, anger, or neutral affect, but not sadness. DP participants exhibited impaired identity memory for happy faces relative to angry, sad, and neutral, whereas ND participants exhibited enhanced facial identity memory when faces were angry. In general, memory for faces was not related to performance at encoding. However, in DP participants only, memory for sad faces was related to sadness recognition at encoding. The results suggest that the negative memory bias for faces in dysphoria does not generalise from long- to short-term memory.     

Brooding rumination and attentional biases in currently non-depressed individuals: an eye-tracking study

Both rumination and attentional biases have been proposed as key components of the RDoC Negative Valence Systems construct of Loss. Although theorists have proposed that rumination, particularly brooding rumination, should be associated with increased sustained attention to depression-relevant information, it is not clear whether this link would be observed in a non-depressed sample or whether it is specific to brooding versus reflective rumination. To address these questions, the current study examined the link between brooding rumination and attentional biases in a sample of non-depressed individuals (n?=?105). Attentional biases were assessed using eye tracking during a passive viewing task in which participants were presented with 2?×?2 arrays of angry, happy, sad, and neutral faces. In line with predictions, higher levels of brooding rumination were associated with greater sustained attention to sad faces and less sustained attention to happy faces. These results remained significant after controlling for participants’ prior history of major depression and current nonclinical level of depressive symptoms, suggesting that the link between brooding rumination and attentional biases is at least partially independent of current or past depression.     

Is this happiness I see? Biases in the identification of emotional facial expressions in depression and social phobia

The present study was designed to examine the operation of depression-specific biases in the identification or labeling of facial expression of emotions. Participants diagnosed with major depression and social phobia and control participants were presented with faces that expressed increasing degrees of emotional intensity, slowly changing from a neutral to a full-intensity happy, sad, or angry expression. The authors assessed individual differences in the intensity of facial expression of emotion that was required for the participants to accurately identify the emotion being expressed. The depressed participants required significantly greater intensity of emotion than did the social phobic and the control participants to correctly identify happy expressions and less intensity to identify sad than angry expressions. In contrast, social phobic participants needed less intensity to correctly identify the angry expressions than did the depressed and control participants and less intensity to identify angry than sad expressions. Implications of these results for interpersonal functioning in depression and social phobia are discussed.     

Attention for emotional facial expressions in dysphoria: an eye-movement registration study

Former research demonstrated that depression is associated with dysfunctional attentional processing of emotional information. Most studies examined this bias by registration of response latencies. The present study employed an ecologically valid measurement of attentive processing, using eye-movement registration. Dysphoric and non-dysphoric participants viewed slides presenting sad, angry, happy and neutral facial expressions. For each type of expression, three components of visual attention were analysed: the relative fixation frequency, fixation time and glance duration. Attentional biases were also investigated for inverted facial expressions to ensure that they were not related to eye-catching facial features. Results indicated that non-dysphoric individuals were characterised by longer fixating and dwelling on happy faces. Dysphoric individuals demonstrated a longer dwelling on sad and neutral faces. These results were not found for inverted facial expressions. The present findings are in line with the assumption that depression is associated with a prolonged attentional elaboration on negative information.     

老年抑郁个体注意偏向的发生阶段

本研究以老年抑郁量表、自评抑郁量表和汉密顿抑郁量表为工具筛选出老年抑郁个体和老年正常对照组为研究对象,通过空间线索化范式,以及分离的情绪Stroop范式考察了刺激呈现时间、线索呈现条件对老年抑郁个体注意偏向的影响,并探讨了老年抑郁个体注意偏向的发生阶段。研究结果表明：（1）在空间线索任务中,当刺激呈现时间为250ms或500ms时,老年抑郁组与老年正常组的返回抑制效应在各种情绪刺激下均无显著差异（P>0.05）,即老年抑郁个体没有呈现出对任何情绪刺激类型的注意偏向现象;当刺激呈现时间为750ms或1000ms时,老年抑郁组的返回抑制效应在不同情绪刺激条件下差异显著,F(2, 66)=3.22,P=0.046,而老年正常组则不存在返回抑制效应在情绪刺激类型上的差异（P>0.05）,提示老年抑郁组对不同情绪类型的刺激注意返回抑制能力不同;进一步检验得知：返回抑制效应在悲伤条件下,存在组间差异,分别是F(1, 33)=10.03,P=0.003;F(1, 33)=18.21,P=0.000,即老年抑郁组的返回抑制效应弱于老年正常组。（2）在Stroop实验中,老年抑郁组在单中性、双中性与单悲伤面孔、中性悲伤面孔、双悲伤面孔线索类型下的反应时差异显著;且当线索类型为单悲伤面孔、中性悲伤面孔、双悲伤面孔时,老年抑郁组与老年正常组的反应时差异均显著,即老年抑郁组的反应时明显长于老年正常组,F(1, 41) = 5.37,P=0.026;F(1, 41) = 7.08,P=0.011;F(1, 41) = 7.28,P=0.010;而当线索类型为单中性和双中性面孔时,老年抑郁组与老年正常组的反应时差异不显著（P>0.05）;提示抑郁组可能在自动化注意选择分配期存在注意偏向。研究认为,老年抑郁个体的注意偏向可能发生在注意初始分配阶段和解释阶段,且受加工深度的影响。在刺激呈现时间较长的条件下,注意偏向的效应更明显。     

Selective attention to angry faces in clinical social phobia

This study investigated the time course of attentional responses to emotional facial expressions in a clinical sample with social phobia. With a visual probe task, photographs of angry, happy, and neutral faces were presented at 2 exposure durations: 500 and 1250 ms. At 500 ms, the social phobia group showed enhanced vigilance for angry faces, relative to happy and neutral faces, in comparison with normal controls. In the 1250-ms condition, there were no significant attentional biases in the social phobia group. Results are consistent with a bias in initial orienting to threat cues in social anxiety. Findings are discussed in relation to recent cognitive models of anxiety disorders.     

Memory-based attentional biases: Anxiety is linked to threat avoidance

The purpose of the present research was to examine if anxiety is linked to a memory-based attentional bias, in which attention to threat is thought to depend on implicit learning. Memory-based attentional biases were defined and also demonstrated in two experiments. A total of 168 university students were shown a pair of faces that varied in their emotional $ content (angry, neutral, and happy), with each type of emotion being consistently preceded by a particular neutral cue face, appearing in the same position. Eye movements were measured during these cue faces and during the emotional faces. The results of two experiments indicated that anxiety was connected with a tendency to avert one's gaze from the positions of angry faces to the positions of happy faces, before these were shown on the screen. This, in turn, caused a reduced perception of angry relative to happy faces. In Experiment 2, participants were also not aware of having a memory-based attentional bias.     

Covert and overt orienting of attention to emotional faces in anxiety

Attentional biases for emotional faces were investigated in high, medium, and low anxiety groups (N = 54) using a probe detection task. Four types of facial expression (threat, sad, happy, neutral) were used to examine the specificity of the bias. Attentional bias measures were derived from manual reaction times (RTs) to probes and the direction of initial eye movement (EM) to the faces. The RT data indicated enhanced vigilance for threat rather than neutral faces in high and medium, but not low, state anxiety. The bias for negative faces appeared to be a combined function of stimulus threat value and the individual's anxiety level. The RT bias did not seem to depend on overt orienting, as many participants made few EMs. However, those who made frequent EMs to the faces showed concordance between the RT and EM bias measures, and so the RT measure of attentional bias for negative versus positive faces at 500 ms appears to provide a valid index of the direction of initial orienting to emotional stimuli. There was no evidence of an anxiety - related bias for happy faces (predicted by the emotionality hypothesis), nor a dysphoria - related bias for sad faces. However, increased dysphoria scores were associated with reduced attentiveness to happy faces.     

Intergenerational transmission of attentional bias and anxiety

Earlier evidence has revealed a bi‐directional causal relationship between anxiety and attention biases in adults and children. This study investigated the prospective and concurrent relations between anxiety and attentional bias in a sample of 89 families (mothers, fathers, and first‐born children). Parents’ and children's attentional bias was measured when children were 7.5 years old, using both a visual probe task and visual search task with angry versus happy facial expressions. Generalized and social anxiety symptoms in parents and children were measured when children were 4.5 and 7.5 years old. Anxiety in parents and children was prospectively (but not concurrently) related to their respective attentional biases to threat: All participants showed a larger attentional bias to threat in the visual search (but not in the visual probe) task if they were more anxious at the 4.5 (but not at the 7.5) year measurement. Moreover, parents’ anxiety levels were prospectively predictive of the visual search attentional bias of their children after controlling for child anxiety. More anxiety in mothers at 4.5 years was related to a faster detection of angry among happy faces, while more anxiety in fathers predicted a faster detection of happy among angry faces in children at 7.5 years. We found no direct association between parental and child attentional biases. Our study contributes to the recently emerging literature on attentional biases as a potential mechanism in the intergenerational transmission of anxiety by showing that parents’ anxiety rather than parents’ attentional bias contributes to the intergenerational transmission of risk for child anxiety.     

Individual differences in emotional reactivity moderate the strength of the relationship between attentional and implicit-memory biases towards threat-related stimuli

The study investigated whether the strength of the relationship between attentional and implicit-memory biases for threat-related material can be moderated by individual differences in temperament and personality. A spatial cueing task, where task-irrelevant angry, happy, and neutral faces acted as spatial cues preceding a target, was immediately followed by an unexpected “old/new” task involving previously presented faces. Temperament-based emotional reactivity (ER; one's typical response strength to emotional stimuli) predicted improved memory performance for angry faces in the “old/new” task. Critically, the relationship between the attentional bias towards threat (indexed by a cue validity index, i.e., a difference in response times on trials where cues with angry expression were presented in the same versus different location to the subsequent target) and enhanced implicit-memory for previously presented task-irrelevant threat-related information was found to be moderated by ER. The current findings provide the first evidence that temperament traits can offer novel insights into the mechanisms enhancing cognitive biases towards threat in the typical population.     

More than just another face in the crowd: superior detection of threatening facial expressions in children and adults

Threatening facial expressions can signal the approach of someone or something potentially dangerous. Past research has established that adults have an attentional bias for angry faces, visually detecting their presence more quickly than happy or neutral faces. Two new findings are reported here. First, evidence is presented that young children share this attentional bias. In five experiments, young children and adults were asked to find a picture of a target face among an array of eight distracter faces. Both age groups detected threat‐relevant faces – angry and frightened – more rapidly than non‐threat‐relevant faces (happy and sad). Second, evidence is presented that both adults and children have an attentional bias for negative stimuli overall. All negative faces were detected more quickly than positive ones in both age groups. As the first evidence that young children exhibit the same superior detection of threatening facial expressions as adults, this research provides important support for the existence of an evolved attentional bias for threatening stimuli.     

At face value: Categorization goals modulate vigilance for angry faces

The present research demonstrates that the attention bias to angry faces is modulated by how people categorize these faces. Since facial expressions contain psychologically meaningful information for social categorizations (i.e., gender, personality) but not for non-social categorizations (i.e., eye-color), angry facial expression should especially capture attention during social categorization tasks. Indeed, in three studies, participants were slower to name the gender of angry compared to happy or neutral faces, but not their color (blue or green; Study 1) or eye-color (blue or brown; Study 2). Furthermore, when different eye-colors were linked to a personality trait (introversion, extraversion) versus sensitivity to light frequencies (high, low), angry faces only slowed down categorizations when eye-color was indicative of a social characteristic (Study 3). Thus, vigilance for angry facial expressions is contingent on people's categorization goals, supporting the perspective that even basic attentional processes are moderated by social influences.