fMRI of parents of children with Asperger Syndrome: a pilot study

BACKGROUND: People with autism or Asperger Syndrome (AS) show altered patterns of brain activity during visual search and emotion recognition tasks. Autism and AS are genetic conditions and parents may show the 'broader autism phenotype.' AIMS: (1) To test if parents of children with AS show atypical brain activity during a visual search and an empathy task; (2) to test for sex differences during these tasks at the neural level; (3) to test if parents of children with autism are hyper-masculinized, as might be predicted by the 'extreme male brain' theory. METHOD: We used fMRI during a visual search task (the Embedded Figures Test (EFT)) and an emotion recognition test (the 'Reading the Mind in the Eyes' (or Eyes) test). SAMPLE: Twelve parents of children with AS, vs. 12 sex-matched controls. DESIGN: Factorial analysis was used to map main effects of sex, group (parents vs. controls), and sexxgroup interaction on brain function. An ordinal ANOVA also tested for regions of brain activity where females>males>fathers=mothers, to test for parental hyper-masculinization. RESULTS ON EFT TASK: Female controls showed more activity in extrastriate cortex than male controls, and both mothers and fathers showed even less activity in this area than sex-matched controls. There were no differences in group activation between mothers and fathers of children with AS. The ordinal ANOVA identified two specific regions in visual cortex (right and left, respectively) that showed the pattern Females>Males>Fathers=Mothers, both in BA 19. RESULTS ON EYES TASK: Male controls showed more activity in the left inferior frontal gyrus than female controls, and both mothers and fathers showed even more activity in this area compared to sex-matched controls. Female controls showed greater bilateral inferior frontal activation than males. This was not seen when comparing mothers to males, or mothers to fathers. The ordinal ANOVA identified two specific regions that showed the pattern Females>Males>Mothers=Fathers: left medial temporal gyrus (BA 21) and left dorsolateral prefrontal cortex (BA 44). CONCLUSIONS: Parents of children with AS show atypical brain function during both visual search and emotion recognition, in the direction of hyper-masculinization of the brain. Because of the small sample size, and lack of age-matching between parents and controls, such results constitute a pilot study that needs replicating with larger samples.     

Effectiveness of students and parents in a psycho-educational intervention programme for children with learning problems

This study investigated the effects of involving two sources of ‘non-traditional manpower’ — namely, university students and parents — in a programme of psycho-educational intervention. It was predicted that, while intervention for children with learning problems would produce significant changes in their perceptions in relation to their families, in their scholastic skills and in their adjustment, the additional involvement of their parents would lead to even greater changes. To test this prediction, 36 children referred to a university Education Clinic were randomly divided into three equal-sized groups: youth counselling plus parent counselling (E₁), youth counselling (E₂), and a control group (C). While the hypothesised changes following intervention were not statistically demonstrated, clinical data did yield support for the effectiveness and potential value of the intervention programmes.     

A low-cost video game applied for training of upper extremity function in children with cerebral palsy: a pilot study

The aim of the present study was to determine the user satisfaction of the EyeToy for the training of the upper limb in children with cerebral palsy (CP). User satisfaction was measured in 12 children with CP, using a postexperience questionnaire, primarily based on a presence questionnaire. In general, children with CP were satisfied with and motivated by the EyeToy training. In addition, a first evaluation study was performed to determine the effect of this training method on the upper limb function. Ten children with CP were randomly assigned to the intervention (mean age 11 years, 9 months; SD 2,3) and the control group (mean age 12 years, 3 months; SD 3,2). After a treatment period of 6 weeks, the intervention group completed a user satisfaction questionnaire. Functional outcome was measured using the Melbourne Assessment scores. Percentage scores of the Melbourne Assessment of 7 of the 10 children were the same or changed only 1% to 2% from baseline to followup. However, in the experimental group, two children improved more, 9% and 13% respectively. In conclusion, it can be said that the EyeToy is a motivational training tool for the training of children with CP and has the potential to improve upper extremity function.     

Dopamine transporter gene moderates response to behavioral parent training in children with ADHD: a pilot study

There is great variability in the degree to which children with attention deficit/hyperactivity disorder (ADHD) improve through behavioral treatments. This study investigates the influence of the dopamine transporter gene (SCL6A3/DAT1) on outcome of behavioral parent training (BPT). Study subjects were a subsample (n = 50, for whom DAT1 genotypes were available) of a randomized controlled BPT effectiveness study (N = 94) comparing BPT plus ongoing routine clinical care (RCC) versus RCC alone in referred children (4-12 years old) with ADHD. Treatment outcome was based on parent-reported ADHD symptoms and behavioral problems. Presence of 2 versus no or 1 DAT1 10-repeat allele served as moderator variable. Time × Treatment × Genotype effect was analyzed with repeated-measures analysis of variance, controlling for baseline medication status. Results indicate that DAT1 moderated treatment response (p = .009). In children with no or 1 DAT1 10-repeat allele, superior treatment effects of BPT + RCC compared with RCC alone were present (p = .005), which was not the case in children with 2 DAT1 10-repeat alleles (p = .57). Our findings suggest that genetic differences in DAT1 in children with ADHD influence their susceptibility to a behavioral intervention directed at shaping their environment through their parents. The role of the dopamine system in motivation and learning and in the aberrant sensitivity to reinforcement in children with ADHD may explain this moderating effect, given that the management of contingencies is typically addressed in BPT.     

Evaluation of a home-based language training programme with severely mentally handicapped children

A home-based Language Training Programme was carried out with pre-school and school-age severely mentally handicapped children, over a 16–18-month period. Compared to control groups, the experimental groups did not show significantly greater progress on normreferenced measures of language development, although all groups showed significant improvement over time. The implications of these findings are discussed in the light of a number of methodological problems with the study.     

Mindfulness training effects for parents and educators of children with special needs

Parents and teachers of children with special needs face unique social-emotional challenges in carrying out their caregiving roles. Stress associated with these roles impacts parents' and special educators' health and well-being, as well as the quality of their parenting and teaching. No rigorous studies have assessed whether mindfulness training (MT) might be an effective strategy to reduce stress and cultivate well-being and positive caregiving in these adults. This randomized controlled study assessed the efficacy of a 5-week MT program for parents and educators of children with special needs. Participants receiving MT showed significant reductions in stress and anxiety and increased mindfulness, self-compassion, and personal growth at program completion and at 2 months follow-up in contrast to waiting-list controls. Relational competence also showed significant positive changes, with medium-to-large effect sizes noted on measures of empathic concern and forgiveness. MT significantly influenced caregiving competence specific to teaching. Mindfulness changes at program completion mediated outcomes at follow-up, suggesting its importance in maintaining emotional balance and facilitating well-being in parents and teachers of children with developmental challenges. (PsycINFO Database Record (c) 2012 APA, all rights reserved).     

Evaluation of the FASIKI traffic safety programme for parents of cycling children

The voluntary cycling test is an important milestone in traffic education in primary school. Cycling helps to develop traffic competences and traffic sense, it increases the mobility range of children and also improves sustainable mobility. On the other hand, data shows that beginning with school age more children have accidents due to cycling (Drott, Johansson, & Aström, 2008; Funk, 2013). The aim of the paper is to show that a measure that can be easily implemented in given structures could help to enhance safe cycling behaviour of children. The voluntary cycling test for ten-year-old children in Austria was complemented with a short traffic psychological intervention for parents called FASIKI. The main aim of the FASIKI programme is to promote a safe cycling performance for children. Therefore, the programme should show parents the average developmental status of their ten-year-old children, so that they can train them in an adequate way as far as age and competence level is concerned. From a traffic psychological point of view it is important for safe cycling behaviour that parents do not over- or underestimate the traffic competences of their children. The present study aimed to verify the effectiveness of the FASIKI programme using Kirkpatrick’s four level evaluation model. Based on a pre-post design, first changes in knowledge and attitudes of parents who attended the programme as well as the impact of the programme on the practical skills of their children in the voluntary cycling test were assessed. The results show positive effects of the FASIKI programme on both, parents’ knowledge and attitudes, and on children’s practical skills. Parental intentions to do cycling exercises with their children were strengthened. Finally, practical implications and policy recommendations concerning traffic safety for children are discussed.     

Self-awareness training associated with personality traits and sex: a pilot study

107 volunteers learning Reiki-Do self-awareness techniques participated in this study. Results indicate that personality traits in healthy participants might be affected by specific self-awareness training, such as Reiki-Do, with participants' sex playing an independent role.     

Effectiveness of the home‐start parenting support program: Behavioral outcomes for parents and children

This study examined effectiveness of Home‐Start, a program designed to support parents with young children. The aims were (a) to examine whether Home‐Start improved maternal well‐being and (b) to examine whether Home‐Start led to changes in the behavior of mothers or children. Self‐reported and observational data were collected in two waves, using data from 54 mothers and their children between 1.5 and 3.5 years of age who participated in this intervention program for 6 months. These data were compared to 51 comparison families who reported need for parenting support. The results showed a significant improvement in perceived parenting competence, but no effects on maternal depressive moods. Mixed results were found for parenting behavior: Parental consistency and observed sensitivity improved significantly in the Home‐Start group whereas no effects were found on the other parenting variables. Child behavioral problems seemed to diminish at the second measurement in both groups, and therefore these changes cannot be attributed to Home‐Start.     

Home-based family intervention for low-income children with asthma: a randomized controlled pilot study

Low-income African American children have disproportionately higher asthma morbidity and mortality. Education alone may not address barriers to asthma management due to psychosocial stress. This study evaluated the efficacy of a home-based family intervention integrating asthma education and strategies to address stress using a community-based participatory research model. Children age 8 to 13 with poorly controlled asthma and their caregivers were recruited from an urban hospital and an asthma camp. Caregivers with elevated scores on a stress measure were enrolled. Forty-three families were randomized to the 4- to 6-session Home Based Family Intervention (HBFI) or the single session of Enhanced Treatment as Usual (ETAU). All families received an asthma action plan and dust mite covers; children performed spirometry and demonstrated MDI/spacer technique at each home visit. The HBFI addressed family-selected goals targeting asthma management and stressors. Asthma management, morbidity, family functioning, and caregiver stress were assessed at baseline, postintervention, and 6 months after the intervention. ED visits and hospitalizations were ascertained by medical record review for a year after intervention completion. Only one child (5%) in HBFI had an asthma-related hospitalization compared to 7 patients (35%) in ETAU in the year following intervention. Participants in both groups demonstrated improved asthma management and family functioning, and reduced ED visits, symptom days, missed school days, and caregiver stress, but there were no differential treatment effects. The results suggest that a home-based intervention addressing medical and psychosocial needs may prevent hospitalizations for children with poorly controlled asthma and caregivers under stress.     

Comparative effectiveness of CBT interventions for co-morbid chronic pain & insomnia: A pilot study

IntroductionChronic pain is difficult to treat and often precedes or exacerbates sleep disturbances such as insomnia. Insomnia, in turn, can amplify the pain experience. Both conditions are associated with inflammatory processes, which may be involved in the bi-directional relationship between pain and sleep. Cognitive behavioral therapy (CBT) for pain and CBT for insomnia are evidence based interventions for, respectively, chronic pain and insomnia. The study objectives were to determine the feasibility of combining CBT for pain and for insomnia and to assess the effects of the combined intervention and the stand alone interventions on pain, sleep, and mood outcomes compared to a control condition.MethodsTwenty-one adults with co-occurring chronic pain and chronic insomnia were randomized to either CBT for pain, CBT for insomnia, combined CBT for pain and insomnia, or a wait-list control condition.ResultsThe combined CBT intervention was feasible to deliver and produced significant improvements in sleep, disability from pain, depression and fatigue compared to the control condition. Overall, the combined intervention appeared to have a strong advantage over CBT for pain on most outcomes, modest advantage over both CBT for insomnia in reducing insomnia severity in chronic pain patients.DiscussionCBT for pain and CBT for insomnia may be combined with good results for patients with co-occurring chronic pain and insomnia.     

Mirror writing in pre-school children: a pilot study

Mirror writing refers to the production of individual letters, whole words or sentences in reverse direction. Unintentional mirror writing has been observed in young children learning to write and interpreted as the manifestation of different cognitive impairments. We report on mirror writing instances in a sample of 108 pre-school children. Results showed MW to be age-related but independent from handedness and left-right discrimination abilities. We propose an account of mirror writing as reflecting dissociation between acquired motor programmes for letter shape composition and unspecified spatial direction of hand movements. Before learning to write, the child’s directional cognitive system is assumed to be dichotomous, thus inducing the production of randomly oriented asymmetrical letters.     

Working parents of children with behavioral problems: a study on the family-work interface

This study examines the process by which child behavioral problems are related to parents' well-being. We developed a family-work spillover model that was tested among 225 working parents. It was hypothesized that family-self conflict (FSC) mediates the relationship between child behavioral problems and parental strain, and that family-work conflict (FWC) mediates the relationship between parental strain and work engagement. Further, it was hypothesized that social support moderates the relationship between child behavioral problems and FSC. The results of (moderated) structural equation modeling supported the mediating role of FSC and FWC and the moderating role of social support. These findings suggest that the negative effects of raising a child with behavioral problems on parental well-being can be buffered by social support.