Hemisphere differences in the effects of cuing in visual recognition tasks.

In Experiment 1 uncued recognition of single letters presented in left or right visual fields showed no hemispheric asymmetry, but cuing by alternatives produced a left-hemisphere advantage. Uncued recognition of words was better in the right visual field (left hemisphere), and this advantage was unchanged by cuing by alternatives or cuing by class. In Experiment 2 a mixed series of words, digits, and dots was presented. Uncued trials showed no asymmetry, but when a precue indicated which type or stimulus would appear next, a left-hemisphere advantage for words was evident. Cuing also produced a nonsignificant shift toward a left-hemisphere advantage for digits and a right-hemisphere advantage for dots. The asymmetrical effects of cuing can be explained by Kinsbourne's attentional model of lateralization, which suggests that cuing may selectively activate one hemisphere, and so bias attention toward the contralateral visual field. Repetition effects within and between visual fields were analyzed but no asymmetries were found.     

Deficits in temporal sequencing of verbal material: The effect of laterality of lesion

Temporal sequencing of verbal materials (digits, words, and geometric forms) presented in two sensory modalities (auditory and visual) to three groups of subjects (Broca's with left anterior lesions, patients with right hemisphere lesions, and normals) was examined. Each subject was asked to point to a set of stimuli in the same sequence as presented by the examiner. Results indicated that patients with left hemisphere lesions were more impaired on all tasks than the right hemisphere lesioned patients who, in turn, were impaired compared to normal controls. Response to auditory presentation was superior to response to visual presentation. Also, digits were the easiest for all groups, and words were easier than geometric forms. Of special interest was the finding which suggested that right hemisphere lesions are associated with impairment of verbal temporal sequencing under either auditory or visual presentation.     

Attention and hemispheric differences in reaction time during simultaneous audio-visual tasks

The effect of different types of competing auditory tasks on laterality differences in visual perception was investigated. Right-handed subjects were presented with digits which occurred randomly in the left or right visual fields. They responded vocally to previously specified digits in a go, no-go reaction time situation. In the absence of any competing auditory task, digits presented in the right visual field were processed more quickly. This visual field difference in reaction time was in the same direction while subjects performed a secondary musical task. However, when a secondary verbal task had to be performed, digits in the left visual field received faster responses. The results support the view that the right hemisphere is capable of some language functions, and that hemispheric differences in performance have at their basis a quantitative asymmetry, which can be reversed even in normal subjects by overloading their limited capacity.     

Emotional valence and arousal effects on memory and hemispheric asymmetries

This study examined predictions based upon the right hemisphere (RH) model, the valence–arousal model, and a recently proposed integrated model (Killgore & Yurgelun-Todd, 2007) of emotion processing by testing immediate recall and recognition memory for positive, negative, and neutral verbal stimuli among 35 right-handed women. Building upon methodologies of previous studies, we found that words presented to the right visual field/left hemisphere (RVF/LH) were recalled and recognized more accurately than words presented to the left visual field/right hemisphere (LVF/RH), and we found significant valence by visual field interactions. Some findings were consistent with one of the models evaluated whereas others were consistent with none of the models evaluated. Our findings suggest that an integration of the RH and valence–arousal models may best account for the findings with regard to hemispheric lateralization of memory for emotional stimuli.     

Concurrent processing of spatial relations and objects in two cerebral hemispheres

This study examined hemispheric asymmetry for concurrent processing of object and spatial information. Participants viewed two successive stimuli, each of which consisted of two digits and two pictures that were randomly located and judged them as identical or different. A sample stimulus was presented in a central visual field, followed by a matching stimulus presented briefly in a left or right visual field. The matching stimuli were different from the sample stimuli with respect to the object (digit or picture) or spatial (locations or distances of items) aspect. No visual field asymmetry was found in the detection of object change. However, a left visual field advantage was found in the detection of spatial change. This result can be explained by the double filtering by frequency theory of Ivry and Robertson, who asserted that the left hemisphere has a bias for processing information contained in relatively high spatial frequencies whereas the right hemisphere has a bias for processing information contained in relatively low spatial frequencies. Based upon this evidence, the importance of interhemispheric integration for visual scene perception is discussed.     

Phonological processing of words in right- and left-handers

It is commonly accepted that phonology is the exclusive domain of the left hemisphere. However, this pattern of lateralization, which posits a right visual field advantage, has been questioned by several studies. In fact, certain factors such as characteristics of the stimuli and subjects' handedness can modulate the right visual field advantage. Thus, the goal of this study was to compare the hemispheric dynamics of right-handers and left-handers during a divided visual field presentation of words that varied in terms of their phonological transparency. For non-transparent words, the left hemisphere seems more competent in both handedness groups. With regard to transparent words, the right hemisphere of both groups also appears competent. Surprisingly, left-handers achieved optimal processing with a functionally isolated left hemisphere, whereas right-handers needed the participation of both hemispheres. The pattern of performance cannot be fully explained by either the callosal or the direct access model.     

Differential visual field-interhemispheric transfer: can it explain sex and handedness differences in lateralization?

104 men and women were tested for visual field-hemispheric transfer of spatial information on a dot-localization task. Right-handed subjects showed significant improvement when stimuli were presented to the left visual field of the right hemisphere (LVF-RH) after practice on the same task presented to the right visual field of the left hemisphere (RVF-LH) first. No improvement was found when the task was presented in the reverse order (LVF-RH first followed by RVF-LH). It was concluded that, for right-handers, transfer of spatial information to the right hemisphere is facilitated while transfer to the left hemisphere is inhibited. Left-handed subjects demonstrated no significant improvement in either condition, suggesting inhibition or lack of transfer of spatial information in either direction. No sex differences were found in either right-handed or left-handed subjects. The findings suggest that there may be different mechanisms underlying the similarities in functional lateralization of women and left-handers.     

The effect of auditory input on cerebral laterality

Cerebral laterality was examined for third-, fourth-, and fifth-grade deaf and hearing subjects. The experimental task involved the processing of word and picture stimuli presented singly to the right and left visual hemifields. The analyses indicated the deaf children were faster than the hearing children in overall processing efficiency, and that they performed differently in regard to hemispheric lateralization. The deaf children processed the stimuli more efficiently in the right hemisphere, while the hearing children demonstrated a left-hemisphere proficiency. This finding is discussed in terms of the hypothesis that cerebral lateralization is influenced by auditory processing.     

Hemispheric specialization in reading and word recognition

Three experiments dealing with hemispheric specialization are presented. In Experiment 1, words and/or faces were presented tachistoscopically to the left or right of fixation. Words were more accurately identified in the right visual field and faces were more accurately identified in the left visual field. A forced choice error analysis for words indicated that errors made for word stimuli were most frequently visually similar words and this effect was particularly pronounced in the left visual field. Two additional experiments supported this finding. On the basis of the results, it was argued that word identification is a multistage process, with visual feature analysis carried out by the right hemisphere and identification and naming by the left hemisphere. In addition, Kinsbourne's attentional model of brain function was rejected in favor of an anatomical model which suggests that simultaneous processing of verbal and nonverbal information does not constrict the attention of either hemisphere.     

Hemisphere differences for components of mental rotation

The hemispheric functional lateralization of components of mental rotation performance was investigated. Twenty right-handed males were presented with rotated alphanumerics and unfamiliar characters in the left or right visual field. Subjects decided if the laterally presented stimulus was identical to or a mirror image of a center standard stimulus. Reaction time and errors were measured. Previous mental rotation findings were replicated and the visual field variable produced significant effects for both dependent measures. An overall right visual field advantage was observed in the latency data, suggesting a left hemisphere superiority for at least one component process of the task. A significant interaction in the error data showed that alphanumerics produced less errors in the right visual field than in the left visual field, consistent with a left hemisphere superiority for processing verbal symbolic material. No such hemispheric difference in accuracy was found for unfamiliar characters.     

Cerebral lateralization of deaf and hearing individuals for linguistic comparison judgments.

A group of congenitally deaf adults and a group of hearing adults, both fluent in sign language, were tested to determine cerebral lateralization. In the most revealing task, subjects were given a series of trials in which they were fist presented with a videotaped sign and then with a word exposed tachistoscopically to the right visual field or left visual field, and were required to judge whether the word corresponded to the sign or not. The results suggested that the comparison processes involved in the decision were performed more efficiently by the left hemisphere for hearing subjects and by the right hemisphere for deaf subjects. However, the deaf subjects performed as well as the hearing subjects in the left hemisphere, suggesting that the deaf are not impeded by their auditory-speech handicap from developing the left hemisphere for at least some types of linguistic processing.     

Form-Specific Visual Priming in the Left and Right Hemispheres

Word fragment completion performance was examined for items that were presented in the same or different letter case at study and test. During the study phase words and nonwords were presented at central fixation, then during the test phase a divided visual field technique was used in which word fragments were presented briefly to the right hemisphere (left visual field) or the left hemisphere (right visual field). Previous research using the word stem completion task indicated that only the right hemisphere was sensitive to case changes in words from study to test. In contrast, the current results indicate that in the fragment completion task the priming effects for the test items presented to either hemisphere were greater when the fragments were in the same compared to different letter case at study and test. These results indicate that both hemispheres are capable of supporting form-specific visual implicit memory.     

Ratings of emotion in faces are influenced by the visual field to which stimuli are presented

This experiment was designed to assess the differential impact of initially presenting affective information to the left versus right hemisphere on both the perception of and response to the input. Nineteen right-handed subjects were presented with faces expressing happiness and sadness. Each face was presented twice to each visual field for an 8-sec duration. The electro-oculogram (EOG) was monitored and fed back to subjects to train them to keep their eyes focused on the central fixation point as well as to eliminate trials confounded by eye movement artifact. Following each slide presentation, subjects rated the intensity of the emotional expression depicted in the face and their emotional reaction to the face on a series of 7-point rating scales. Subjects reported perceiving more happiness in response to stimuli initially presented to the left hemisphere (right visual field) compared to presentations of the identical faces to the right hemisphere (left visual field). This effect was predominantly a function of ratings on sad faces. A similar, albeit less robust, effect was found on self-ratings of happiness (the degree to which the face elicited the emotion in the viewer). These data challenge the view that the right hemisphere is uniquely involved in all emotional behavior. The implications of these findings for theories concerning the lateralization of emotional behavior are discussed.     

Lateralized interhemispheric transfer of color cues: evidence for dynamic coding principles of visual lateralization in pigeons

Visual feature discrimination tasks in pigeons reveal a right eye/left hemisphere dominance at the population level. Anatomical studies and lesion data show this visual lateralization to be related to asymmetries of the tectofugal system, which ascends from the tectum over the n. rotundus to the forebrain. Anatomically, this system is characterized by numerous morphological and connectional asymmetries which result in a bilateral visual representation in the dominant left hemisphere and a mostly contralateral representation in the subdominant right hemisphere. Ontogenetically, visual lateralization starts with an asymmetrical embryonic position within the egg, which leads to asymmetries of light stimulation. Differences in exposure to light stimulation between the eyes result in activity differences between the ascending tectofugal pathways of the left and the right hemisphere, which are transcribed during a critical time span into morphological asymmetries. The asymmetries established after this transient period finally start to determine the lateralized processes of the visual system for the entire life span of the individual. We now can show that these anatomical lateralizations are accompanied by asymmetries of interocular transfer, which enable a faster shift of learned color cues from the dominant right to the left eye than vice versa. In summary, our data provide evidence that cerebral asymmetries are based both on "static" anatomical and on "dynamic" process-dependent principles.     

Hemispheric differences in processing handwritten cursive

Hemispheric asymmetry was examined for native English speakers identifying consonant-vowel-consonant (CVC) non-words presented in standard printed form, in standard handwritten cursive form or in handwritten cursive with the letters separated by small gaps. For all three conditions, fewer errors occurred when stimuli were presented to the right visual field/left hemisphere (RVF/LH) than to the left visual field/right hemisphere (LVF/RH) and qualitative error patterns indicated that the last letter was missed more often than the first letter on LVF/RH trials but not on RVF/LH trials. Despite this overall similarity, the RVF/LH advantage was smaller for both types of cursive stimuli than for printed stimuli. In addition, the difference between first-letter and last-letter errors was smaller for handwritten cursive than for printed text, especially on LVF/RH trials. These results suggest a greater contribution of the right hemisphere to the identification of handwritten cursive, which is likely related visual complexity and to qualitative differences in the processing of cursive versus print.     

Individual differences in spatial relation processing: effects of strategy, ability, and gender

Numerous studies have focused on the distinction between categorical and coordinate spatial relations. Categorical relations are propositional and abstract, and often related to a left hemisphere advantage. Coordinate relations specify the metric information of the relative locations of objects, and can be linked to right hemisphere processing. Yet, not all studies have reported such a clear double dissociation; in particular the categorical left hemisphere advantage is not always reported. In the current study we investigated whether verbal and spatial strategies, verbal and spatial cognitive abilities, and gender could account for the discrepancies observed in hemispheric lateralization of spatial relations. Seventy-five participants performed two visual half field, match-to-sample tasks (Van der Ham, van Wezel, Oleksiak, & Postma, 2007; Van der Ham, Raemaekers, van Wezel, Oleksiak, and Postma, 2009) to study the lateralization of categorical and coordinate relation processing. For each participant we determined the strategy they used in each of the two tasks. Consistent with previous findings, we found an overall categorical left hemisphere advantage and coordinate right hemisphere advantage. The lateralization pattern was affected selectively by the degree to which participants used a spatial strategy and by none of the other variables (i.e., verbal strategy, cognitive abilities, and gender). Critically, the categorical left hemisphere advantage was observed only for participants that relied strongly on a spatial strategy. This result is another piece of evidence that categorical spatial relation processing relies on spatial and not verbal processes.     

Visual field asymmetries in numerical size comparisons of digits, words, and signs

Visual field asymmetries were examined in American Sign Language-English bilinguals for speeded numerical size judgments of pairs of digits, number words, and number signs. Physical size of the number pairs was either congruent or incongruent with their numerical size. The results revealed a greater left visual field (LVF) interference for numbers represented as digits and a greater right visual field (RVF) interference for numbers represented as words or signs. Subjects' performance on number words and signs was also influenced by their skill in English and ASL: interference was greater in the RVF in the subjects' better language but was greater in the LVF for the less skilled language. These findings suggest that lateralization of numerical size judgments is moderated by the mode of number presentation and by prior language experience.     

Hemisphere differences in conscious and unconscious word reading

Hemisphere differences in word reading were examined using explicit and implicit processing measures. In an inclusion task, which indexes both conscious (explicit) and unconscious (implicit) word reading processes, participants were briefly presented with a word in either the right or the left visual field and were asked to use this word to complete a three-letter word stem. In an exclusion task, which estimates unconscious word reading, participants completed the word stem with any word other than the prime word. Experiment 1 showed that words presented to either visual field were processed in very similar ways in both tasks, with the exception that words in the right visual field (left hemisphere) were more readily accessible for conscious report. Experiment 2 indicated that unconsciously processed words are shared between the hemispheres, as similar results were obtained when either the same or the opposite visual field received the word stem. Experiment 3 demonstrated that this sharing between hemispheres is cortically mediated by testing a split-brain patient. These results suggest that the left hemisphere advantage for word reading holds only for explicit measures; unconscious word reading is much more balanced between the hemispheres.     

Visual field differences in the processing of numerical stimuli

Twenty-four right-handed subjects received random presentations of the numbers 1-6 in the form of words, digits, and dot patterns, to the left and right visual fields. Accuracy and reaction time were recorded for an odd-even judgment requiring a manual response. A significant stimulus type of visual field interaction was obtained, with words showing a left-hemisphere advantage and digits and dot patterns showing a right-hemisphere advantage. This pattern supports Coltheart's (1980, Deep dyslexia: A right hemisphere hypothesis, In M. Coltheart, K. Patterson, & J.C. Marshall (Eds.), Deep dyslexia, London: Routledge & Kegan Paul) right hemisphere reading hypothesis, which suggests that the left hemisphere's general advantage in processing linguistic material may be specific to stimuli which involve phonological processing. When phonological processing is not possible (e.g., for arabic digits and other ideographic orthographies), the right hemisphere may have an advantage because of its superior visuospatial processing capabilities.