Endogenous attention modulates early selective attention in psychopathy: An ERP investigation

Psychopathic individuals are prone to act on urges without adequate consideration of future consequences or the rights of other individuals. One interpretation of this behavior is that it reflects abnormal selective attention (i.e., a failure to process information that is incongruent with their primary focus of attention; Hiatt, Schmitt, & Newman, Neuropsychology, 18, 50-59, 2004). Unfortunately, it is unclear whether this selective attention abnormality reflects top-down endogenous influences, such as the strength or specificity of attention focus (i.e., top-down set) apart from other, more exogenous (bottom-up), effects on attention. To explore this question, we used an early visual event-related potential (N2pc) in combination with a modified visual search task designed to assess the effect of early endogenous (i.e., top-down) attention on the processing of set-congruent information. The task was administered to a sample of 70 incarcerated adult males, who were assigned to high, intermediate, and low psychopathy groups using Hare’s Psychopathy Checklist-Revised (Hare, 2003). Based on the assumption that their failure to process set-incongruent information reflects the exaggerated effects of endogenous attention, we predicted that participants with high psychopathy scores would show an exaggerated N2pc response to set-congruent information. The results supported the hypothesis and provide novel electrophysiological evidence that psychopathy is associated with exaggerated endogenous attention effects during early stages of processing. Further research is needed to examine the implications of this finding for the well-established failure of psychopathic individuals to process set-incongruent information and inhibit inappropriate responses.     

Recognition of facial affect in psychopathic offenders

The authors examined the reliability of facial affect processing deficits found in psychopathic individuals (R. Blair et al., 2004) and whether they could be modified by attentional set. One hundred eleven offenders, classified using the Psychopathy Checklist--Revised (R. Hare, 2003) and Welsh Anxiety Scale (G. Welsh, 1956), performed a facial affect recognition task under 2 conditions. On the basis of research linking psychopathy, amygdala dysfunction, and deficits in facial affect recognition, the authors predicted that psychopathic offenders would display performance deficits when required to identify the emotional expression of particular faces. In addition, given evidence linking the affective processing deficits in psychopathy to focus of attention, the authors predicted that any deficits in facial affect processing would disappear when participants could anticipate which affective cues would be relevant on a given trial. Contrary to expectation, psychopathic offenders performed as well as controls in both conditions. The authors conclude that the conditions that reveal affective deficits in psychopathic individuals require further specification.     

Self-relevance enhances the benefits of attention on perception

ABSTRACT

Considerable efforts have focused on elucidating the influence that self-relevance exerts on perceptual decision-making. To explore this issue further, the current research explored the extent to which stimulus applicability facilitates the benefits of covert attention on early visual processing. In two experiments, we manipulated the personal-relevance of peripheral cues (i.e., geometric shapes) that preceded the appearance of target stimuli (i.e., Gabors) and asked participants to report the orientation of the stimulus with the highest contrast. The results revealed a significant effect of self-relevance on task performance. First, compared to cues associated with a friend or stranger, self-relevant cues enhanced the apparent contrast of a stimulus. Second, the benefits of self-relevance were most pronounced when cues pertained to identities that were significant (vs. trivial or irrelevant) to observers. Together, these findings demonstrate that self-relevance potentiates the benefits of transient attention on stimulus processing.     

The interplay of attention and emotion: top-down attention modulates amygdala activation in psychopathy

Psychopathic behavior has long been attributed to a fundamental deficit in fear that arises from impaired amygdala function. Growing evidence has demonstrated that fear-potentiated startle (FPS) and other psychopathy-related deficits are moderated by focus of attention, but to date, no work on adult psychopathy has examined attentional modulation of the amygdala or concomitant recruitment of relevant attention-related circuitry. Consistent with previous FPS findings, here we report that psychopathy-related differences in amygdala activation appear and disappear as a function of goal-directed attention. Specifically, decreased amygdala activity was observed in psychopathic offenders only when attention was engaged in an alternative goal-relevant task prior to presenting threat-relevant information. Under this condition, psychopaths also exhibited greater activation in selective-attention regions of the lateral prefrontal cortex (LPFC) than did nonpsychopaths, and this increased LPFC activation mediated psychopathy’s association with decreased amygdala activation. In contrast, when explicitly attending to threat, amygdala activation did not differ in psychopaths and nonpsychopaths. This pattern of amygdala activation highlights the potential role of LPFC in mediating the failure of psychopathic individuals to process fear and other important information when it is peripheral to the primary focus of goal-directed attention.     

Threat processing in obsessive-compulsive disorder: evidence from a modified negative priming task

Individuals with obsessive-compulsive disorder (OCD) often experience intrusive thoughts. These intrusions may be due to biases in information processing mechanisms, including attention, memory, and learning. To examine this hypothesis, we presented a modified negative priming (NP) paradigm with idiographically selected words to 19 individuals with OCD (OCs) and 19 matched non-anxious control participants (NACs). The words included OCD-relevant threat, OCD-relevant positive, and neutral words. This paradigm typically elicits positive priming because participants may learn the contingency between the prime and probe that facilitates responding [Frings and Wentura (2006). Strategy effects counteract distractor inhibition: NP with constantly absent probe distractors. Journal of Experimental Psychology: Human Perception and Performance, 32, 854-864]. As predicted, NACs showed facilitation (i.e., positive priming) rather than NP for all word types, whereas OCs exhibited facilitation for only neutral words. For positive words, OCs exhibited no priming and for threat words they exhibited NP. These results suggest that for idiographic, OCD-relevant threat information, individuals with OCD show difficulty learning the contingency between the information in the prime and probe displays relative to the NACs.     

Divided Visual Attention and Left Hemisphere Activation Among Psychopathic and Nonpsychopathic Offenders

Recent divided attention studies suggest the impulsive antisocial behavior of psychopaths may be related to deficient processing of information under conditions that place substantial demands on left-hemisphere-specific processing resources (left hemisphere activation (LHA) hypothesis; D. S. Kosson [1996, 1998]). To examine performance under conditions constraining eye movements and covert shifts of attention, 26 psychopathic and 46 nonpsychopathic inmates completed a divided attention task in which lateralized stimuli appeared briefly and simultaneously in the left visual field (LVF) and right visual field (RVF) of a monitor. Targets were either presented primarily in the RVF to induce LHA or were equiprobable in LVF and RVF to promote equal activation (EA) of left and right hemisphere resources. Psychopaths were less accurate than nonpsychopaths only under LHA conditions; within-group comparisons also revealed a substantial decrement from EA to LHA only in psychopaths. Thus, psychopaths’ performance deficits were specific to conditions priming left hemisphere resources asymmetrically.     

Attention Network Performance and Psychopathic Symptoms in Early Adolescence: An ERP Study

Reaction time (RT) and event-related potential (ERP) measures were used to examine the relationships between psychopathic symptoms and three major attention networks (alerting, orienting, and executive attention) among a community sample of youth. Antisocial Process Screening Device (APSD; Frick and Hare 2001) total and subscale scores were negatively correlated with ERP measures of attentional alerting, indicating that youth with psychopathic symptoms had difficulty using warning cues to prepare for upcoming targets. APSD total scores were not related to performance on measures of orienting or executive attention, although weaker executive attention was found among youth with higher scores on the Impulsivity subscale. These findings support attention-based models of psychopathy and provide evidence of specific deficits in attentional alerting among youth with psychopathic traits. Deficiencies in attentional alerting may be related to noradrenergic functioning and may have cascading effects on higher order cognitive and affective processing.     

Emotional processing of individuals high in psychopathic traits

One of the most important clinical features of psychopaths is their differential emotional response style. The present study examined the modulating effect of negative mood induction on the processing of emotional information and its relation to psychopathy. The sample of 105 participants were randomly assigned to two types of mood induction conditions (negative vs neutral) and viewed three types of visual stimuli (positive, neutral, negative). Psychopathic Personality Inventory‐R (PPI‐R; Lilienfeld & Andrews) was employed to measure their psychopathic traits. It was hypothesized that individuals high on PPI‐II (i.e., self‐centered impulsivity) would show greater response latencies to emotionally negative pictures when they were induced into a negative mood compared to individuals high on PPI‐I (i.e., fearless dominance). In general, individuals high on PPI‐II showed greater response latencies to emotionally negative pictures, but their responsivity did not vary as a function of mood manipulation or task demands. When controlling the influence of other PPI factors, PPI‐I predicted reaction time (RT) facilitation to positive pictures in general (i.e., faster RT), and when interacting with a negative mood induction, it predicted longer viewing time of and more difficulty disattending from positive pictures (i.e., slower RT). These results were discussed within emotional processing theory associated with psychopathy.     

Specifying the attentional selection that moderates the fearlessness of psychopathic offenders

Our previous research demonstrated that psychopathy-related fear deficits involve abnormalities in attention that undermine sensitivity to peripheral information. In the present study, we specified this attention-mediated abnormality in a new sample of 87 prisoners assessed with Hare's Psychopathy Checklist-Revised (Hare, 2003). We measured fear-potentiated startle (FPS) under four conditions that crossed attentional focus (threat vs. alternative) with early versus late presentation of threat cues. The psychopathic deficit in FPS was apparent only in the early-alternative-focus condition, in which threat cues were presented after the alternative goal-directed focus was established. Furthermore, psychopathy interacted with working memory capacity in the late-alternative-focus condition, which suggests that individuals high in psychopathy and working memory capacity were able to maintain a set-related alternative focus that reduced FPS. The results not only provide new evidence that attention moderates the fearlessness of psychopathic individuals, but also implicate an early attention bottleneck as a proximal mechanism for deficient response modulation in psychopathy.     

Context cue focality influences strategic prospective memory monitoring

Monitoring the environment for the occurrence of prospective memory (PM) targets is a resource-demanding process that produces cost (e.g., slower responding) to ongoing activities. However, research suggests that individuals are able to monitor strategically by using contextual cues to reduce monitoring in contexts in which PM targets are not expected to occur. In the current study, we investigated the processes supporting context identification (i.e., determining whether or not the context is appropriate for monitoring) by testing the context cue focality hypothesis. This hypothesis predicts that the ability to monitor strategically depends on whether the ongoing task orients attention to the contextual cues that are available to guide monitoring. In Experiment 1, participants performed an ongoing lexical decision task and were told that PM targets (TOR syllable) would only occur in word trials (focal context cue condition) or in items starting with consonants (nonfocal context cue condition). In Experiment 2, participants performed an ongoing first letter judgment (consonant/vowel) task and were told that PM targets would only occur in items starting with consonants (focal context cue condition) or in word trials (nonfocal context cue condition). Consistent with the context cue focality hypothesis, strategic monitoring was only observed during focal context cue conditions in which the type of ongoing task processing automatically oriented attention to the relevant features of the contextual cue. These findings suggest that strategic monitoring is dependent on limited-capacity processing resources and may be relatively limited when the attentional demands of context identification are sufficiently high.     

The influence of reduced visual acuity on age-related decline in spatial working memory: an investigation

To investigate the relationship between visual acuity and cognitive function with aging, we compared low-vision and normally-sighted young and elderly individuals on a spatial working memory (WM) task. The task required subjects to memorise target locations on different matrices after perceiving them visually or haptically. The haptic modality was included as a control to look at the effect of aging on memory without the confounding effect of visual deficit. Overall, age and visual status did not interact to affect WM accuracy, suggesting that age does not exaggerate the effects of visual deprivation. Young participants performed better than the elderly only when the task required more operational processes (i.e., integration of information). Sighted participants outperformed the visually impaired regardless of testing modality suggesting that the effect of the visual deficit is not confined to only the most peripheral levels of information processing. These findings suggest that vision, being the primary sensory modality, tends to shape the general supramodal mechanisms of memory.     

Intentional and automatic processing of numerical information in mathematical anxiety: testing the influence of emotional priming

ABSTRACT

Current theoretical approaches suggest that mathematical anxiety (MA) manifests itself as a weakness in quantity manipulations. This study is the first to examine automatic versus intentional processing of numerical information using the numerical Stroop paradigm in participants with high MA. To manipulate anxiety levels, we combined the numerical Stroop task with an affective priming paradigm. We took a group of college students with high MA and compared their performance to a group of participants with low MA. Under low anxiety conditions (neutral priming), participants with high MA showed relatively intact number processing abilities. However, under high anxiety conditions (mathematical priming), participants with high MA showed (1) higher processing of the non-numerical irrelevant information, which aligns with the theoretical view regarding deficits in selective attention in anxiety and (2) an abnormal numerical distance effect. These results demonstrate that abnormal, basic numerical processing in MA is context related.     

Target selection difficulty, negative priming, and aging

It has been recently suggested that the presence of identity negative priming effects in old adults could occur when there is substantial processing of the distracting information in a selective attention task (J. M. Kieley & A. A. Hartley, 1997). In three experiments, using a letter identification task, it was found that making target selection more difficult increased the magnitude of the negative priming effect to a similar extent in both young and old adults. Moreover, the size of the negative priming effect did not differ between young and elderly participants. These results are discussed with respect to the issue of age-related deficits in the mechanisms underlying negative priming.     

Psychopathy, risk taking, and attention: a differentiated test of the somatic marker hypothesis

A. R. Damasio's (1994) somatic marker hypothesis relates psychopathy to deficits in the ventromedial prefrontal cortex. Using the gambling task (A. Bechara, A. R. Damasio, H. Damasio, & S. Anderson, 1994), the authors tested this premise and the role of attention as a moderator. Forty-nine male prison inmates were assessed with the Psychopathy Checklist--Revised (R. D. Hare, 1991), the gambling task, and standardized tests on attention-concentration, and intelligence. Results revealed no general relation between psychopathy and gambling task performance. However, psychopathic inmates with low attention scores gambled worse than did the attentive ones. They also had more previous convictions. In nonpsychopathic individuals, attention had no impact. Different processing strategies for psychopathic and nonpsychopathic individuals are proposed to explain these findings.     

Processing head fakes in basketball: Are there ironic effects of instructions on the head-fake effect in basketball?

Instructions in sports are used to improve athletes’ performance. However, instructions can also impair performance if they direct athletes’ attention to a to-be-avoided behavior which paradoxically provokes exactly that behavior (ironic effect). The present study investigates the impact of different instructions on the head-fake effect in basketball. Specifically, we asked here if deliberate attempts to ignore the deceptive cues gaze direction and head orientation increase the impact of that information and thus, paradoxically increase the head-fake effect. We found that the detrimental impact of spatially incongruent gaze direction and head orientation was essentially independent of whether participants were, or were not, instructed to deliberately ignore the task-irrelevant information. Hence, deceptive actions exert their impact independent of the perceivers’ attempts to ignore deceptive cues. We thus conclude that the deceptive cues gaze direction and head orientation are per se hyper-accessible or over-salient and its processing cannot be controlled with any amount of mental capacity (and even not with the non-ironic instruction). However, as both ignore instructions produce general processing costs (i.e., slower reactions) coaches should solely instruct athletes’ to focus attention on the processing of the pass direction.     

Differentiating emotional processing and attention in psychopathy with functional neuroimaging

Individuals with psychopathy are often characterized by emotional processing deficits, and recent research has examined the specific contexts and cognitive mechanisms that underlie these abnormalities. Some evidence suggests that abnormal features of attention are fundamental to emotional deficits in persons with psychopathy, but few studies have demonstrated the neural underpinnings responsible for such effects. Here, we use functional neuroimaging to examine attention–emotion interactions among incarcerated individuals (n = 120) evaluated for psychopathic traits using the Hare Psychopathy Checklist–Revised (PCL-R). Using a task designed to manipulate attention to emotional features of visual stimuli, we demonstrate effects representing implicit emotional processing, explicit emotional processing, attention-facilitated emotional processing, and vigilance for emotional content. Results confirm the importance of considering mechanisms of attention when evaluating emotional processing differences related to psychopathic traits. The affective-interpersonal features of psychopathy (PCL-R Factor 1) were associated with relatively lower emotion-dependent augmentation of activity in visual processing areas during implicit emotional processing, while antisocial-lifestyle features (PCL-R Factor 2) were associated with elevated activity in the amygdala and related salience network regions. During explicit emotional processing, psychopathic traits were associated with upregulation in the medial prefrontal cortex, insula, and superior frontal regions. Isolating the impact of explicit attention to emotional content, only Factor 1 was related to upregulation of activity in the visual processing stream, which was accompanied by increased activity in the angular gyrus. These effects highlight some important mechanisms underlying abnormal features of attention and emotional processing that accompany psychopathic traits.     

The effect of semantic context on prospective memory performance

The current study provides evidence for spontaneous processing in prospective memory (PM) or memory for intentions. Discrepancy-plus-search is the spontaneous processing of PM cues via disruptions in processing fluency of ongoing task items. We tested whether this mechanism can be demonstrated in an ongoing rating task with a dominant semantic context. Ongoing task items were manipulated such that the PM cues were members of a semantic category (i.e., Body Parts) that was congruent or discrepant with the dominant semantic category in the ongoing task. Results showed that participants correctly responded to more PM cues when there was a category discrepancy between the PM cues and ongoing task items. Moreover, participants' identification of PM cues was accompanied by faster ongoing task reaction times when PM cues were discrepant with ongoing task items than when they were congruent. These results suggest that a discrepancy-plus-search process supports PM retrieval in certain contexts, and that some discrepancy-plus-search mechanisms may result from the violation of processing expectations within a semantic context.     

How prioritized is self-prioritization during stimulus processing?

Recent research has suggested that self-relevance automatically enhances stimulus processing (i.e., the self-prioritization effect). Notably, information associated with one’s self elicits faster responses than comparable material associated with other targets (e.g., friend, stranger). Challenging the assertion that self-prioritization is an obligatory process, here we hypothesized that self-relevance only facilitates performance when task sets draw attention to previously formed target-object associations. The results of two experiments were consistent with this viewpoint. Compared with arbitrary objects owned by a friend, those owned by the self were classified more rapidly when participants were required to report either the owner or identity of the items (i.e., semantic task set). In contrast, self-relevance failed to facilitate performance when participants judged the orientation of the stimuli (i.e., perceptual task set). These findings demonstrate the conditional automaticity of self-prioritization during stimulus processing.     

The Influence of Reduced Visual Acuity on Age-Related Decline in Spatial Working Memory: An Investigation

ABSTRACT

To investigate the relationship between visual acuity and cognitive function with aging, we compared low-vision and normally-sighted young and elderly individuals on a spatial working memory (WM) task. The task required subjects to memorise target locations on different matrices after perceiving them visually or haptically. The haptic modality was included as a control to look at the effect of aging on memory without the confounding effect of visual deficit. Overall, age and visual status did not interact to affect WM accuracy, suggesting that age does not exaggerate the effects of visual deprivation. Young participants performed better than the elderly only when the task required more operational processes (i.e., integration of information). Sighted participants outperformed the visually impaired regardless of testing modality suggesting that the effect of the visual deficit is not confined to only the most peripheral levels of information processing. These findings suggest that vision, being the primary sensory modality, tends to shape the general supramodal mechanisms of memory.