Exploring gene-environment interactions: socioregional moderation of alcohol use.

Examples of gene-environment interaction in human behavioral data are relatively rare; those that exist have used simple, dichotomous measures of the environment. The authors describe a model that allows for the specification of more continuous, more realistic variations in environments as moderators of genetic and environmental influences on behavior. Using data from a population-based Finnish twin study, the authors document strong moderating effects of socioregional environments on genetic and environmental influences on adolescent alcohol use, with nearly a five-fold difference in the magnitude of genetic effects between environmental extremes. The incorporation of specific environmental measures into genetically informative designs should prove to be a powerful method for better understanding the nature of gene-environment interaction and its contribution to the etiology of behavioral variation.     

Maternal expressed emotion predicts children's antisocial behavior problems: using monozygotic-twin differences to identify environmental effects on behavioral development

If maternal expressed emotion is an environmental risk factor for children's antisocial behavior problems, it should account for behavioral differences between siblings growing up in the same family even after genetic influences on children's behavior problems are taken into account. This hypothesis was tested in the Environmental Risk Longitudinal Twin Study with a nationally representative 1994-1995 birth cohort of twins. The authors interviewed the mothers of 565 five-year-old monozygotic (MZ) twin pairs and established which twin in each family received more negative emotional expression and which twin received more warmth. Within MZ pairs, the twin receiving more maternal negativity and less warmth had more antisocial behavior problems. Qualitative interviews were used to generate hypotheses about why mothers treat their children differently. The results suggest that maternal emotional attitudes toward children may play a causal role in the development of antisocial behavior and illustrate how genetically informative research can inform tests of socialization hypotheses.     

Genetic and environmental influences on behavior: capturing all the interplay

Basic quantitative genetic models of human behavioral variation have made clear that individual differences in behavior cannot be understood without acknowledging the importance of genetic influences. Yet these basic models estimate average, population-level genetic and environmental influences, obscuring differences that might exist within the population and masking systematic transactions between specific genetic and environmental influences. This article discusses a newer, more sophisticated and powerful quantitative genetic model that articulates these transactions. Results from this model highlight the ways in which the gene- environment interaction and correlation are intertwined. They can be used to integrate findings from quantitative and molecular genetic studies and to understand the roles of genetic influences and social forces in manifested behaviors, even when DNA sequence variation is not relevant.     

Fine-tuning nativism: the ��nurtured nature�� and innate cognitive structures

S. Oyama’s prominent account of the Parity Thesis states that one cannot distinguish in a meaningful way between nature-based (i.e. gene-based) and nurture-based (i.e. environment-based) characteristics in development because the information necessary for the resulting characteristics is contained at both levels. Oyama as well as P. E. Griffiths and K. Stotz argue that the Parity Thesis has far-reaching implications for developmental psychology in that both nativist and interactionist developmental accounts of psychological capacities that presuppose a substantial nature/nurture dichotomy are inadequate. We argue that well-motivated abandoning of the nature/nurture dichotomy, as advocated in converging versions of the Parity Thesis in biology, does not necessarily entail abandoning the distinction between biologically given abilities necessary for the development of higher psychological capacities and the learning process they enable. Thus, contrary to the claims of the aforementioned authors, developmental psychologists need not discard a substantial distinction between innate (biologically given) characteristics and those acquired by learning, even if they accept the Parity Thesis. We suggest a two-stage account of development: the first stage is maturational and involves interaction of genetic, epigenetic and environmental causes, resulting in the endogenous biological ‘machinery’ (e.g. language acquisition device), responsible for learning in the subsequent stage of the developmental process by determining the organism’s responses to the environment. This account retains the crux of nativism (the endogenous biological structure determines the way the organism learns/responds to an environment) whilst adopting the developmentalist view of biology by characterizing environments as distinctly different in terms of structure and function in two developmental stages.     

Reliability of the UCLA Loneliness Scale in Opiate Dependent Individuals

Previous research has supported theoretical claims that dichotomous thinking may be a risk factor for suicide. However, the concept of dichotomous thinking is vague, and thus far, no measures of it have been developed. This study developed a coding scheme useful on Thematic Aperception Test (TAT; Murray, 1943) protocols and applicable to other verbal productions to refine the concept of dichotomous thinking and to assess its utility as a predictor of suicidality. Suicidal patients had a significantly elevated rate of a narrowly defined type of dichotomous thinking involving diametric or polarized possibilities. However, suicidal and nonsuicidal patients did not differ on weaker forms of dichotomous thinking involving nonexclusive or nonbinary alternatives. Suicidal patients produced shorter TAT stories than nonsuicidal patients, supporting other findings in the literature that suicidal patients tend to be cognitively and affectively shut down. Traditionally designated suicide cards also yielded shorter stories but did not elicit higher rates of dichotomous thinking.     

Conceptual and methodological issues in examining behavioral development through environment-organism interactions

The importance of understanding behavior in terms of interactions between organismic and environmental variables has become more salient and calls for research focused on such interactions have been made. However, several conceptual paths may encourage investigating and understanding behavior in terms of organism-environment interactions. One such path is the development and testing of constructs which cut across the traditional organism-environment dichotomy and conceptualize behavioral development as fundamentally an organism-environment interaction. In this paper, a metatheoretical framework for thinking about behavioral development as fundamentally an organism-environment interaction is presented. Issues involved in conceptualizing and examining behavior and behavioral development as fundamentally an organism-environment interaction are also examined by reviewing the concept of affordances and some of the illustrative research that has been conducted. From the review, it is suggested that research which attempts to understand behavior as inseparably a function of organism-environment interactions will benefit if additional methodological avenues are developed. Marken's (1997, Psychological Methods, 2, 436–446) test for controlled variables is presented as an example of one such method. Finally, suggestions for developing the ideas reviewed in this paper for other research domains (i.e., anxiety in children) are also presented.     

Neighborhood deprivation affects children's mental health: environmental risks identified in a genetic design

The possibility that neighborhood conditions affect children's development has captured much attention because of its implications for prevention. But does growing up in deprived neighborhoods matter above and beyond a genetic liability to behavior problems, if genetically vulnerable families tend to concentrate in poor neighborhoods? A nationwide study of 2-year-old twins shows that children in deprived neighborhoods were at increased risk for emotional and behavioral problems over and above any genetic liability. Environmental factors shared by members of a family accounted for 20% of the population variation in children's behavior problems, and neighborhood deprivation accounted for 5% of this family-wide environmental effect. The results suggest that the link between poor neighborhoods and children's mental health may be a true environmental effect, and demonstrate that genetic designs are environmentally informative and can be used to identify modifiable risk factors for promoting child health.     

A behavior-analytic critique of Bandura's self-efficacy theory

A behavior-analytic critique of self-efficacy theory is presented. Self-efficacy theory asserts that efficacy expectations determine approach behavior and physiological arousal of phobics as well as numerous other clinically important behaviors. Evidence which is purported to support this assertion is reviewed. The evidence consists of correlations between self-efficacy ratings and other behaviors. Such response-response relationships do not unequivocally establish that one response causes another. A behavior-analytic alternative to self-efficacy theory explains these relationships in terms of environmental events. Correlations between self-efficacy rating behavior and other behavior may be due to the contingencies of reinforcement that establish a correspondence between such verbal predictions and the behavior to which they refer. Such a behavior-analytic account does not deny any of the empirical relationships presented in support of self-efficacy theory, but it points to environmental variables that could account for those relationships and that could be manipulated in the interest of developing more effective treatment procedures.     

How anxiety induces verbal hallucinations

Verbal hallucinations are often associated with pronounced feelings of anxiety, and it has also been suggested that anxiety somehow triggers them. In this paper, we offer a phenomenological or ‘personal-level’ account of how it does so. We show how anxious anticipation of one’s own thought contents can generate an experience of their being ‘alien’. It does so by making an experience of thinking more like one of perceiving, resulting in an unfamiliar kind of intentional state. This accounts for a substantial subset of verbal hallucinations, which are experienced as falling within one’s psychological boundaries and lacking in auditory qualities.     

有关进化心理学局限性的理论思考

进化心理学是现代西方心理学的新取向之一。这一新取向吸引了众多的追随者,但是它自身的核心假设、方法论和认识论方面却存在着局限性。文章从三个方面分析了这种局限性：第一,进化心理学的核心假设是心理的模块性观点。依据这种观点,心灵由大量功能各异的心理模块组成,但是来自于心理学和生物学的研究都表明这种观点是缺乏科学依据的。第二,进化心理学从过去的角度理解现在,所依据的事实大多是推测性的,更多的是一种历史叙事,从方法论的角度来说,这种研究不具备可证伪性,不符合科学方法论的基本原则。第三,在认识论方面,进化心理学继承了社会生物学的传统,有意或无意地夸大了基因的作用,贬低了个体发展过程中其它因素,现代生命科学的研究已经证明了基因决定论的虚假性     

Relational operants: processes and implications: a response to Palmer's review of Relational Frame Theory

Palmer has recently criticized Relational Frame Theory (RFT) on the grounds that it has developed data in search of a principle. In this reply, we show that he has done so by attacking fundamental concepts within behavior analysis itself, including the functional nature of an operant and contingencies of reinforcement as a behavioral process. His claim that RFT appeals to new behavioral principles to explain the development of relational operants is shown to be incorrect: As with any operant, RFT appeals to a history of contacted consistencies in contingencies across multiple ex-emplars to explain them. New principles only emerge later as a logically necessary extension of such operants if they exist--a view that Palmer failed to address or appreciate. Palmer's desire to see the use of methods other than matching-to-sample is proper but already largely satisfied in the empirical literature on RFT. We show Palmer's defense of Skinner's definition of verbal behavior to be illogical and unresponsive to the empirical challenge behavior analysis faces. Palmer's alternative common sense mediational associationistic account is another in more than a century of such accounts, all of which have failed empirically. At its root, Palmer's criticism is based on a mechanistic philosophy that is hostile to a traditional functional behavior analytic approach.     

Effect of dichotomous thinking on the association of depression with BMI and weight change among obese females

This study tested whether a dichotomous thinking style moderates the association of depression with body mass, and investigated the effect of dichotomous thinking and depression on weight loss during a cognitive behavioural therapy (CBT) intervention.Overweight and obese females (n = 76) participated in CBT for weight management for 12 weeks. Before treatment, dichotomous thinking moderated the association of depression with BMI, such that depression was positively associated with BMI among those with low dichotomous thinking, but was not associated among those with high dichotomous thinking. Weight loss was negatively associated with pre-treatment depression and frequency of treatment attendance, but not with dichotomous thinking. Females who regard their weight as unacceptably high and who think dichotomously may experience high levels of depression irrespective of their actual weight, while depression may be proportionate to the degree of obesity among those who do not think dichotomously. Depression, but not dichotomous thinking, is likely to interfere with the ability to adhere to short-term weight loss strategies.     

A genetically informed study of marital instability and its association with offspring psychopathology

Parental divorce is associated with a number of emotional and behavioral problems in young-adult offspring, but theoretical and empirical considerations suggest that the relation may be partially or fully accounted for by passive gene-environment correlation or environmental selection characteristics. The current study used the Children of Twins Design to explore whether shared environmental or genetic factors confound the relationship between parental marital instability and measures of psychopathology. Comparisons of the offspring of adult twins in Australia on 3 factors of abnormal behavior, including drug and alcohol, behavioral, and internalizing problems, suggest that environmental influences associated with divorce account for the higher rates of psychopathology. The results are consistent with a causal connection between marital instability and psychopathology in young-adult offspring.     

Before Analogy: Recovering Barth'sOntological Development

What is the nature of Barth's development over the 1920s? Barth himself understood this period as his "apprenticeship," and cites his 1931 book on Anselm as a significant juncture in moving beyond this stage in his thinking. Barth's emphasis upon both change and continuity lies at the heart of the discrepancy between two prominent interpreters of his theology, Hans Urs von Balthasar and Bruce McCormack. On the surface it appears as though their disagreement centers around Barth's employment of dialectic and analogy in his theology. However, our thesis is that this focus conceals the ontological strategies Barth's multifarious uses of analogy and dialectic always implied. Although McCormack is right to suggest that Balthasar's depiction of a shift from dialectic to analogy is inadequate, in the end McCormack's account of Barth's development over the 1920s conceals as much as it reveals. The following essay attempts to demonstrate the kinds of insights which can be made of the past accounts of Barth's development which focused on the transition from dialectic to analogy. Far from relegating these accounts to the sidelines, McCormack's work helps us see all the more clearly just what was at stake in figures like Balthasar's work. By looking past McCormack and Balthasar's respective periodizations of Barth's development, a clearer focus upon Barth's theological ontology can begin to take place.     

Behavior Genetics: What's New? What's Next?

What's new in behavior genetics? With widespread acceptance that nearly all behavioral variation reflects some genetic influence, current studies are investigating developmental changes in the nature and magnitude of genetic and environmental effects, the extent to which different behaviors are influenced by common genes, and different forms of gene-environment correlation and interaction. New designs, focused on assessment of unrelated children in the same households or neighborhood environments, and use of measured environmental variables within genetically informative designs, are yielding more incisive evidence of common environmental effects on behavior. What will be next? Behavior genetic techniques and analyses will be used to inform efforts to find genes altering susceptibility for disorder and dispositional genes affecting behavioral variation. The developing integration of behavioral and molecular genetics will identify genes influencing specific behavioral variation and enhance understanding of how they do so. Psychologists will play a pivotal role in communicating that understanding to the public and in facilitating consideration of the inevitable ethical issues then to be confronted.     

Beliefs, experiences and misplaced being: an interactionist account of delusional misidentification

This paper contrasts an interactionist account of delusional misidentification with more traditional one- and two-stage models. Unlike the unidirectional nature of these more traditional models, in which the aetiology of the disorder is said to “progress” from a neurological disruption via an anomalous experience to a delusional belief, the interactionist account posits the interaction of top-down and bottom-up processes to better explain the maintenance of the delusional belief. In addition, it places a greater emphasis on the patient’s underlying phenomenal experience in accounting for the specificity of the delusional content. The role played by patient phenomenology is examined in light of Ratcliffe’s recent phenomenological account. Similarities and differences are discussed. The paper concludes that a purely phenomenological account is unable to differentiate between non-delusional patient groups, who have what appear to be equivalent phenomenal experiences to patients suffering from delusional misidentification but without the delusional belief, and delusional groups, something the interactionist model is able to do.     

Children's understanding of belief as a normative concept

The variety of accounts of theory of mind development, arising from distinct theoretical perspectives, have focused on children's causal-explanatory views on the mind and have not developed accounts of children's normative judgments of the mental domain. This review maintains that such a focus is unfortunate and leaves our understanding of belief as a concept incomplete. First, by presenting an alternative framework that treats belief as a normative concept, this account discusses the central importance of children's understanding of epistemic justification and their appreciation of the normative significance of others’ reasons for belief. Next, this review of the relevant theory of mind literature proposes a new way of thinking about the findings of various domains in this field and gives particular attention to prior work on false belief, origins or sources of belief, and the distinctions between fantastical and epistemic states. On the basis of this review, it is concluded that in order to accurately assess the development of the concept of belief, further research is required on children's views of how beliefs ought to be formed, their evaluation of justified and unjustified believers, and the notions of duty or responsibility they associate with epistemic agents.     

An interactionist interpretation of sex differences in violence

An interactionist analysis of violence processes is used as a framework to account for sex differences in parameters of violent behavior. Starting with the observation that violence is often an outcome of negotiations of situated identity, sex differences in the extent of violence and the selection of victim are interpreted. In addition, the symmetry of social relationships specifies the processes generating interpersonal violence. The paper argues that interactionist concepts can be used to make theoretical sense of differences in rates of behavior. Strictly structural explanations are thereby informed by an understanding of the processual character of social interaction.