发展的认知神经科学--神经科学与认知发展研究的融合点

本文介绍了发展的神经科学自 2 0世纪 80年代以来在早期突触形成、关键期及丰富环境对脑发育的影响等领域的一些突出成就 ,阐述了从神经科学与认知发展共同研究的主题来考察两个学科的整合的意义 ,并对发展的认知神经科学研究的未来趋势作了展望。     

How to Exploit Diversity for Scientific Gain: Using Individual Differences to Constrain Cognitive Theory

ABSTRACT— People often show considerable systematic variability in their ability to perform many different cognitive tasks. In this article, we argue that by combining an individual-differences approach with an experimental-cognitive-neuroscience approach one can often further constrain potential theories of the underlying cognitive mechanisms. In support of this proposal, we outline three basic benefits of using an individual-differences approach: validating neurophysiological measures, demonstrating associations among constructs, and demonstrating dissociations among apparently similar constructs. To illustrate these points, we describe recent work by us and other researchers that utilizes each of these techniques to address specific questions within the domain of visual working memory. It is our hope that some of these techniques for utilizing individual variability may be applied to other domains within cognitive neuroscience.     

The developmental cognitive neuroscience of functional connectivity

Developmental cognitive neuroscience is a rapidly growing field that examines the relationships between biological development and cognitive ability. In the past decade, there has been ongoing refinement of concepts and methodology related to the study of ‘functional connectivity’ among distributed brain regions believed to underlie cognition and behavioral control. Due to the recent availability of relatively easy-to-use tools for functional connectivity analysis, there has been a sharp upsurge of studies that seek to characterize normal and psychopathologically abnormal brain functional integration. However, relatively few studies have applied functional and effective connectivity analysis techniques to developmental cognitive neuroscience. Functional and effective connectivity analysis methods are ideally suited to advance our understanding of the neural substrates of cognitive development, particularly in understanding how and why changes in the functional ‘wiring’ of neural networks promotes optimal cognitive control throughout development. The purpose of this review is to summarize the central concepts, methods, and findings of functional integration neuroimaging research to discuss key questions in the field of developmental cognitive neuroscience. These ideas will be presented within a context that merges relevant concepts and proposals from different developmental theorists. The review will outline a few general predictions about likely relationships between typical ‘executive’ cognitive maturation and changes in brain network functional integration during adolescence. Although not exhaustive, this conceptual review also will showcase some of recent findings that have emerged to support these predictions.     

认知神经科学的心理学理论价值

从认知神经科学面临的三个挑战--(1)神经科学是“还原” 的,不能完全解释一个人的心理活动过程;（2）认知神经科学无法真正解释人的心理与行为;（3）认知神经科学只能揭示出神经事件与认知活动或行为活动的相关性--入手来讨论其心理学理论价值,阐明认知神经科学在心理学研究中的重要地位及主流趋势。同时指出,认知神经科学只是心理学学科门类中的一种,它能解决的问题也只限于特定的范围,对它要有科学理性的认识和定位。     

I move, therefore I am: a new theoretical framework to investigate agency and ownership

The neurocognitive structure of the acting self has recently been widely studied, yet is still perplexing and remains an often confounded issue in cognitive neuroscience, psychopathology and philosophy. We provide a new systematic account of two of its main features, the sense of agency and the sense of ownership, demonstrating that although both features appear as phenomenally uniform, they each in fact are complex crossmodal phenomena of largely heterogeneous functional and (self-)representational levels. These levels can be arranged within a gradually evolving, onto- and phylogenetically plausible framework which proceeds from basic non-conceptual sensorimotor processes to more complex conceptual and meta-representational processes of agency and ownership, respectively. In particular, three fundamental levels of agency and ownership processing have to be distinguished: The level of feeling, thinking and social interaction. This naturalistic account will not only allow to “ground the self in action”, but also provide an empirically testable taxonomy for cognitive neuroscience and a new tool for disentangling agency and ownership disturbances in psychopathology (e.g. alien hand, anarchic hand, anosognosia for one’s own hemiparesis).     

A nonlinear dynamic artificial neural network model of memory

Nonlinearity and dynamics in psychology are found in various domains such as neuroscience, cognitive science, human development, etc. However, the models that have been proposed are mostly of a computational nature and ignore dynamics. In those models that do include dynamic properties, only fixed points are used to store and retrieve information, leaving many principles of nonlinear dynamic systems (NDS) aside; for instance, chaos is often perceived as a nuisance. This paper considers a nonlinear dynamic artificial neural network (NDANN) that implements NDS principles while also complying with general neuroscience constraints. After a theoretical presentation, simulation results will show that the model can exhibit multi-valued, fixed-point, region-constrained attractors and aperiodic (including chaotic) behaviors. Because the capabilities of NDANN include the modeling of spatiotemporal chaotic activities, it may be an efficient tool to help bridge the gap between biological memory neural models and behavioral memory models.     

Cognitive psychology in sport: Progress and prospects

ProblemThere has been a recent upsurge of research interest in cognitive sport psychology or the scientific study of mental processes (e.g., mental imagery) in athletes. Despite this interest, an important question has been neglected. Specifically, is research on cognitive processes in athletes influential outside sport psychology, in the “parent” field of cognitive psychology or in the newer discipline of cognitive neuroscience?ObjectivesThe purpose of this paper is to explore the theoretical significance of research on expertise, attention and mental imagery in athletes from the perspective of cognitive psychology and cognitive neuroscience.MethodFollowing analysis of recent paradigm shifts in cognitive psychology and cognitive neuroscience, a narrative review is provided of key studies on expertise, attention and mental imagery in athletes.Results and conclusionsThis paper shows that cognitive sport psychology has contributed significantly to theoretical understanding of certain mental processes studied in cognitive psychology and cognitive neuroscience. It also shows that neuroscientific research on motor imagery can benefit from increased collaboration with cognitive sport psychology. Overall, I conclude that the domain of sport offers cognitive researchers a rich and dynamic natural laboratory in which to study how the mind works.     

Why (and how) should we study the interplay between emotional arousal,Theory of Mind,and inhibitory control to understand moral cognition?

Findings in the field of experimental psychology and cognitive neuroscience have shed new light on our understanding of the psychological and biological bases of morality. Although a lot of attention has been devoted to understanding the processes that underlie complex moral dilemmas, attempts to represent the way in which individuals generate moral judgments when processing basic harmful actions are rare. Here, we will outline a model of morality which proposes that the evaluation of basic harmful actions relies on complex interactions between emotional arousal, Theory of Mind (ToM) capacities, and inhibitory control resources. This model makes clear predictions regarding the cognitive processes underlying the development of and ability to generate moral judgments. We draw on data from developmental and cognitive psychology, cognitive neuroscience, and psychopathology research to evaluate the model and propose several conceptual and methodological improvements that are needed to further advance our understanding of moral cognition and its development.     

Doing cognitive neuroscience: a third way

The “top-down” and “bottom-up” approaches have been thought to exhaust the possibilities for doing cognitive neuroscience. We argue that neither approach is likely to succeed in providing a theory that enables us to understand how cognition is achieved in biological creatures like ourselves. We consider a promising third way of doing cognitive neuroscience, what might be called the “neural dynamic systems” approach, that construes cognitive neuroscience as an autonomous explanatory endeavor, aiming to characterize in its own terms the states and processes responsible for brain-based cognition. We sketch the basic motivation for the approach, describe a particular version of the approach, so-called ‘Dynamic Causal Modeling’ (DCM), and consider a concrete example of DCM. This third way, we argue, has the potential to avoid the problems that afflict the other two approaches.     

近红外光学成像在社会认知神经科学中的应用

社会认知神经科学是运用认知神经科学的研究手段,探讨社会科学问题与理论的多学科交叉领域。近来,功能性近红外光学成像技术(functional near-infrared spectroscopy,fNIRS)凭借生态效度高、成像安全、对头动耐受性高、成本低等优势,成为了该领域新兴的热点技术。无论是在婴儿发育和社会经济决策的单脑研究中,还是在人际互动的多脑研究中,它都有广泛应用。未来近红外光学成像的应用可以向多脑神经反馈、脑机接口技术、设备无线化和多模态成像做进一步探索。     

Psychophysical dualism from the point of view of a working psychologist

Cognitive neuroscience constitutes the third phase of development of the field of cognitive psychophysiology since it was established about half a century ago. A critical historical overview is given of this development, focusing on recurring problems that keep frustrating great expectations. It is argued that psychology has to regain its independent status with respect to cognitive neuroscience and should take psychophysical dualism seriously. A constructive quantum physical model for psychophysical interaction is presented, based on a new stochastic interpretation of the quantum potential in the de Broglie–Bohm theory. This model can be applied to analyze cognitive information processing in psychological experiments. It is shown that the quantum potential shares several features with Duns Scotus’ notion of contingent causality.     

The Emerging (Social) Neuroscience of SES

Social scientists have long been interested in understanding how socioeconomic status (SES) affects the way people think, feel, and behave. Neuroscience has provided new tools (fMRI, EEG, and ERP) to allow us to answer these questions, demonstrating, for example, that lower SES is linked to stronger mirror neural responses, greater mentalizing, enhanced vigilance to threat, and lesser likelihood to spontaneously infer traits based on limited information. The present paper (i) reviews evidence that SES affects neural responses involved in a wide range of psychological processes, (ii) highlights the value of neural methods in investigations of SES, (iii) discusses cultural neuroscience as a potential framework to understand why SES has the effects it does on the brain, (iv) considers previous developmental neuroscience findings regarding SES and attention in light of cultural neuroscience, and (v) discusses future challenges, opportunities, and questions for this emerging field.     

The Interpenetration of Culture and Biology in Human Development

The central argument of this article is that human development should be viewed as the product of the interpenetration1 of cultural and biological processes. Using developmental system theory, it is argued that our work as investigators of human development is to examine this mutual coregulation: how biology and culture interpenetrate over time in concert with developmental processes. Various findings from developmental research are used to provide evidence on (a) how our biology constrains, gives expression to, mediates, or moderates how culture operates on developmental processes and (b) how culture infiltrates and becomes part of our biology and basic developmental processes. Examples of advances in neuroscience are also used to illustrate this interpenetration and to argue for the pervasiveness of cultural influences on development. To conduct the necessary research, new methodologies are needed. Promise is seen in emerging areas of social cognitive neuroscience.     

Computational analyses in cognitive neuroscience: in defense of biological implausibility

Because cognitive neuroscience researchers attempt to understand the human mind by bridging behavior and brain, they expect computational analyses to be biologically plausible. In this paper, biologicallyimplausible computational analyses are shown to have critical and essential roles in the various stages and domains of cognitive neuroscience research. Specifically, biologically implausible computational analyses can contribute to (1) understanding and characterizing the problem that is being studied, (2) examining the availability of information and its representation, and (3) evaluating and understanding the neuronal solution. In the context of the distinct types of contributions made by certain computational analyses, the biological plausibility of those analyses is altogether irrelevant. These biologically implausible models are nevertheless relevant and important for biologically driven research.     

评述早期儿童认知发展的神经科学研究

神经科学的迅猛发展,尤其是神经科学新的研究手段的广泛运用,使得神经科学在儿童早期认知发展的神经机制研究中取得了长足的进展。本文主要涉及神经发育中神经系统的可塑性、关键期,以及知觉、注意、记忆和空间认知等认知发展诸多方面的神经机制。     

现代神经科学发展述略

现代神经科学的产生是神经解剖学、神经生物化学、神经生理学等传统生物学科与神经心理学、认知心理学等行为科学之间不断融合的结果。在神经科学产生与发展历程中,有许多值得研究总结的方法论问题。     

The molecules of social recognition memory: implications for social cognition, extended mind, and neuroethics

Social cognition, cognitive neuroscience, and neuroethics have reached a synthesis of late, but some troubling features are present. The neuroscience that currently dominates the study of social cognition is exclusively cognitive neuroscience, as contrasted with the cellular and increasingly molecular emphasis that has gripped mainstream neuroscience over the past three decades. Furthermore, the recent field of molecular and cellular cognition has begun to unravel some molecular mechanisms involved in social cognition, especially pertaining to the consolidation of memories of particular conspecific organisms. Some new experimental techniques for positive interventions into these hypothesized mechanisms offer opportunities for establishing direct causal linkages between intra-neuronal molecular events and the behaviors used to measure social cognitive phenomena. Predicted results from an experiment described below also cast doubt on the application of the “extended mind” approach from recent cognitive science to ground the neuroscience of social cognition. Since neuroethics relies heavily on our best neuroscience of social cognition, that field may soon need to extend its attention beyond cognitive neuroscience, and into neuroscience’s cellular and molecular mainstream.     

Unconscious fantasy: a once and future concept

The concept of unconscious fantasy should be retained as fundamental to any psychoanalytic approach. The concept is reexamined in the face of two challenges: today's theoretical pluralism and the recent integration of findings from academic research. The first section reviews post-Freudian theoretical contributions to Freud's original concept, concluding that in its evolved form it is flexible enough to serve multiple perspectives. The second section examines four features identified with primary process thinking, demonstrating that a model of early mentation based on adult dream work cannot be supported by research on early development. However, the contemporary concept of unconscious fantasy is compatible with research findings from child development studies and cognitive neuroscience, permitting psychoanalysts to enter dialogue with those fields. Our contribution is not the posit of a new form of thinking (primary process) but an understanding of how general cognitive processes are enlisted for motivated purposes.     

他心问题的社会认知神经科学研究进路

作为当代心智哲学九大问题之一的他心问题,肇始于Descartes主义对心身关系的认识。问的是:我们能否知道以及怎么知道他人有心,亦即有思想、经验和情感等?对于他心问题的解决方案,20世纪90年代以来,随着现当代科学技术(尤其是神经生物学、认知神经科学和大脑测试技术等)的深入发展,哲学家与心理学家的知识联姻和交叉合作研究,提供了关于他心问题的若干重要成果和实证资料。他心问题不再成为"理论的死角"。当代社会认知神经科学的出现(social cognitive neuroscience,SCN,2000),在科学方法论上更加关注对社会性心智现象的神经机制考量,一系列研究成果都为揭示他心问题提供了科学旁证。这不仅说明了认识他心的可能性,而且表明了通向认识他心方式的多样性,物理学的方法并不是与他心相隔绝。本文尝试从社会认知神经科学的最新研究进展:镜像神经元系统,他知与自知、他心知觉和再认的社会标记、他心社会判断和归因入手来论证他心问题的可释性,为他心问题的论证提供一条多学科交叉研究的新进路。