Speech prosody and developmental dyslexia: Reduced phonological awareness in the context of intact phonological representations

Recent research indicates that awareness of the rhythmic patterns present in spoken language (i.e., prosody) may be an important and relatively overlooked predictor of reading ability. Two studies investigated the prosodic processing abilities of skilled adult readers and adults with developmental dyslexia. Participants with dyslexia showed reduced awareness of lexical and metrical stress and these skills were found to be significantly associated with, and predictive of, phonological decoding ability. In contrast, the same individuals showed normal patterns of stress based priming at magnitudes similar to controls. These results—suggesting reduced phonological awareness in the context of intact phonological representations—are consistent with recent findings reported in the domain of phonemic processing. Implications for the phonological deficit theory of dyslexia are discussed.     

发展性阅读障碍的视觉空间注意加工能力

鉴于阅读起始于基础视觉加工阶段, 越来越多的研究者开始关注阅读障碍者的视觉空间注意加工能力。视觉空间注意是指个体对视觉刺激的空间位置的注意, 可通过线索提示、视觉搜索和视觉注意广度等视觉任务来考察。大量国内外研究发现, 发展性阅读障碍者在视觉空间注意任务下表现出行为和神经活动方面的异常。其中的神经机制问题不仅反映在与视觉空间注意有关的顶叶区域激活异常, 还存在于脑区间功能连接异常(如顶叶区域与字形加工区的功能连接)。未来研究还需利用横断和追踪研究探讨阅读障碍与视觉空间注意能力发展关系的内在机制, 以及探究语言特性对阅读障碍者视觉空间注意缺陷的可能调节作用。     

Auditory processing in developmental dyslexia: An exploratory study of an auditory and visual matching training program with Swedish children with developmental dyslexia

This study examined whether training using a nonverbal auditory-visual matching task had a remedial effect on reading skills in developmental dyslexia. The pretest/post-test design was used with Swedish children ( N = 41), between the ages of 7 and 12. Training comprised twice-weekly sessions of 15 minutes, over eight weeks. There was an improvement in auditory-visual matching during the training period. There were also improvements in some reading test scores, especially in reading nonsense words and in reading speed. These improvements in tasks which are thought to rely on phonological processing suggest that such reading difficulties in dyslexia may stem in part from more basic perceptual difficulties, including those required to manage the visual and auditory components of the decoding task. The utility of the concept of auditory structuring is discussed in relation to auditory and phonological processing skills when a child learns to read.     

注意缺陷多动障碍-发展性阅读障碍共患儿童的干预效果及其内在机理

注意缺陷多动障碍和发展性阅读障碍是两类常见的儿童神经发育障碍, 二者共患率高达25%~48%。共患问题不仅使儿童自身面临着严重的认知、行为和心理损害, 还给家庭、学校和社会带来了沉重的负担, 对共患儿童的干预是极为必要且重要的。以共患病理机制假说为基础, 可将既往共患儿童的干预研究划分为以下两大类：(1)基于表型假说的干预方案, 如药物干预、阅读干预以及二者联合干预, 相应方案干预效果的迁移性和稳定性均有待深入考究; (2)基于共同缺陷假说的干预方案, 如针对核心共同认知缺陷之一的加工速度问题的干预已初显成效, 但相关研究较少, 干预效果需更多研究进一步系统性地考察。最后就共患儿童的干预方案现状进行了反思和展望。     

语言和音乐层级结构的加工

语言和音乐在呈现过程中, 小单元相互结合组成更大的单元, 最终形成层级结构。已有研究表明, 听者能够将连续的语流和音乐切分成层级结构, 并在大脑中形成层级表征。在感知基础之上, 听者还能将新出现的语言和音乐事件整合到层级结构之中, 形成连贯理解, 最终顺利地完成交流过程。未来研究应剖析边界线索在层级结构感知中的作用, 考察不同层级整合过程的影响因素, 进一步探索语言和音乐层级结构加工的关系。     

汉语发展性阅读障碍儿童视觉同时性加工技能子成分的发展及其与阅读的关系

通过分别以高频汉字(实验1)和图形非言语材料(实验2)为刺激的两个联合视觉注意任务, 并采用基于Budensen视觉注意理论的参数估计方法, 系统地探查小学三~六年级汉语发展性阅读障碍儿童的视觉同时性加工技能缺陷的内在机制。以43名汉语发展性阅读障碍儿童和46名生理年龄匹配典型发展儿童为被试, 每类被试均被分为小学中年级组(三、四年级)和高年级组(五、六年级)。两个实验均发现不同年级组的阅读障碍儿童在知觉加工速度参数上显著小于控制组儿童。在空间注意分布权重参数上, 实验1的结果显示, 不同于控制组儿童向左侧化发展的注意分布模式, 两个年级组的阅读障碍儿童均表现为无偏的注意分布; 而实验2未发现显著组别差异。且这两种同时性加工子技能分别与不同水平的汉语阅读技能密切相关。结果表明, 汉语阅读障碍儿童在同时加工多个视觉刺激时存在持续的知觉加工速度缓慢的问题, 在同时加工言语类刺激时还表现出异常的空间注意分布模式。本研究有助于从基础认知层面揭示汉语发展性阅读障碍儿童的缺陷机理, 为进一步设计相关的提高阅读效率的干预方案提供理论依据。     

孤独症儿童动作发展障碍的神经机制

动作发展障碍(Developmental motor disorders)是孤独症谱系障碍的常见特征。通过系统回顾孤独症儿童动作发展障碍的神经科学研究, 发现γ-氨基丁酸和5-羟色胺浓度的改变及γ-氨基丁酸相关蛋白和Shank蛋白的表达异常不仅会损害中枢神经系统的发育, 而且还能导致突触兴奋性与抑制性失衡, 进而改变孤独症儿童小脑和大脑皮层运动区的功能连接。孤独症儿童小脑、基底神经节和胼胝体结构的改变对全脑的连通性产生了负面影响。神经生化机制和脑结构的异常共同导致了脑功能的异常, 最终造成孤独症儿童的动作发展障碍。此外, 动作发展障碍与孤独症核心症状共同的神经基础主要包括镜像神经元系统紊乱, 丘脑、基底神经节和小脑异常以及SLC7A5和PTEN 基因突变。未来研究需要关注与运动密切相关的其他神经递质, 如乙酰胆碱和多巴胺; 探索动作发展障碍神经网络的动态机制及其形成; 剖析该障碍的神经机制和自闭症核心症状神经机制的相互作用。     

发展性阅读障碍儿童阅读中的眼跳定位缺陷：基于新词学习的实验证据

通过与生理年龄匹配儿童比较新词重复学习中眼跳定位模式变化的异同, 探讨发展性阅读障碍儿童在新词学习中的眼跳定位是否存在缺陷。以发展性阅读障碍儿童和生理年龄匹配儿童为被试, 采用重复学习新词范式, 结果发现：(1)与生理年龄匹配组相比, 发展性阅读障碍儿童跳入新词的眼跳距离较短、首次注视落点位置更靠近词首; (2)生理年龄匹配组儿童利用学习次数调节新词眼跳定位模式的能力高于发展性阅读障碍儿童, 即随着新词学习次数的增加, 生理年龄匹配组儿童跳入和跳出新词的眼跳距离随之增长, 首次注视落点位置更靠近词中心; 相比之下, 发展性阅读障碍儿童仅在跳出新词的眼跳距离上有所增长, 但增加幅度也显著小于生理年龄匹配组。结果表明, 发展性阅读障碍儿童在新词学习中的眼跳定位, 及利用学习次数对眼跳定位的调节上均表现出一定缺陷。     

Global and local pitch perception in children with developmental dyslexia

This study investigated global versus local pitch pattern perception in children with dyslexia aged between 8 and 11 years. Children listened to two consecutive 4-tone pitch sequences while performing a same/different task. On the different trials, sequences either preserved the contour (local condition) or they violated the contour (global condition). Compared to normally developing children, dyslexics showed robust pitch perception deficits in the local but not the global condition. This finding was replicated in a simple pitch direction task, which minimizes sequencing and short term memory. Results are consistent with a left-hemisphere deficit in dyslexia because local pitch changes are supposedly processed by the left hemisphere, whereas global pitch changes are processed by the right hemisphere. The present data suggest a link between impaired pitch processing and abnormal phonological development in children with dyslexia, which makes pitch pattern processing a potent tool for early diagnosis and remediation of dyslexia.     

Early communicative gestures and play as predictors of language development in children born with and without family risk for dyslexia

The present study investigated early communicative gestures, play, and language skills in children born with family risk for dyslexia (FR) and a control group of children without this inheritable risk at ages 12, 15, 18, and 24 months. Participants were drawn from the Tromsø Longitudinal study of Dyslexia (TLD) which follows children's cognitive and language development from age 12 months through Grade 2 in order to identify early markers of developmental dyslexia. Results showed that symbolic play and parent reported play at age 12 months and communicative gestures at age 15 months explained 61% of the variance in productive language at 24 months in the FR group. These early nonlinguistic measures seem to be potentially interesting markers of later language development in children born at risk for dyslexia.     

Beneficial effects of a music listening intervention on neural speech processing in 0–28-month-old children at risk for dyslexia

Familial risk for developmental dyslexia can compromise auditory and speech processing and subsequent language and literacy development. According to the phonological deficit theory, supporting phonological development during the sensitive infancy period could prevent or ameliorate future dyslexic symptoms. Music is an established method for supporting auditory and speech processing and even language and literacy, but no previous studies have investigated its benefits for infants at risk for developmental language and reading disorders. We pseudo-randomized N∼150 infants at risk for dyslexia to vocal or instrumental music listening interventions at 0–6 months, or to a no-intervention control group. Music listening was used as an easy-to-administer, cost-effective intervention in early infancy. Mismatch responses (MMRs) elicited by speech-sound changes were recorded with electroencephalogram (EEG) before (at birth) and after (at 6 months) the intervention and at a 28 months follow-up. We expected particularly the vocal intervention to promote phonological development, evidenced by enhanced speech-sound MMRs and their fast maturation. We found enhanced positive MMR amplitudes in the vocal music listening intervention group after but not prior to the intervention. Other music activities reported by parents did not differ between the three groups, indicating that the group effects were attributable to the intervention. The results speak for the use of vocal music in early infancy to support speech processing and subsequent language development in infants at developmental risk.

Research Highlights

• Dyslexia-risk infants were pseudo-randomly assigned to a vocal or instrumental music listening intervention at home from birth to 6 months of age.
• Neural mismatch responses (MMRs) to speech-sound changes were enhanced in the vocal music intervention group after but not prior to the intervention.
• Even passive vocal music listening in early infancy can support phonological development known to be deficient in dyslexia-risk.

     

Gyral morphology in the posterior Sylvian region in families affected by developmental language disorder

This study describes the family aggregation of gyral morphology in the posterior perisylvian region in families that contain one or more children with a developmental language disorder. The probands in these families were 8 male and 2 female children referred through therapy programs and schools for children with language and reading problems. Family members included both biological parents (10 m, 10 f) and all available siblings (6 m, 4 f). Gyral morphology in the members of these families was compared with control subjects (10 m, 10 f) who were without a personal or family history of developmental language disorders. Gyral morphology was evaluated using T1-weighted sagittal scans from a GE Signa 1.5T magnet, 5 mm consecutive slices through the full brain volume. A less common type of Sylvian fissure morphology was more frequently found in the hemispheres of language-disordered subjects and their first-degree relatives than in control subjects. In addition, the pattern of Sylvian fissure morphology across generations within the families suggests that this feature might be inherited from either parent. The elevated rate of extra gyri in the posterior perisylvian region in families affected by language disorder links an anomaly within a language-related brain region with familial risk for this disorder.     

音乐干预对自闭症儿童语言障碍的影响

语言障碍是自闭症的核心症状之一,改善自闭症儿童的语言障碍对其日常生活具有重要意义。诸多研究证实音乐干预能够明显改善自闭症儿童的语言障碍。从干预材料的角度出发,音乐干预包括将音乐刺激与语言刺激严格匹配的音乐干预方法以及将音乐作为学习背景的音乐干预方法,二者均能有效促进自闭症儿童的语言表达和交流。目前最有代表性的自闭症语言障碍的音乐干预方法包括听觉动作通路训练(AMMT)、基于旋律的语言沟通治疗(MBCT)以及背景音乐干预方法。音乐干预方法的发展今后需着眼于音乐类型的选择、音乐与其他活动的结合,同时兼顾不同自闭症儿童群体的适用性以及音乐干预在生活中的推广。     

Shared reading interaction in families with and without genetic risk for dyslexia: implications for toddlers’ language development

Shared reading represents a unique context for language learning. Little is known, however, about the quality of shared reading and its developmental implications in families with reading disabilities. In the present study, these questions were addressed in the context of a longitudinal follow‐up. Maternal interactional behaviors and children's participation in a book reading situation were analyzed at 14 months of age in a subsample involving 39 mothers who were diagnosed as reading disabled and had a familial background of reading difficulties (the RD group) and 89 normally reading mothers (the NR group) and their children. Information on the children's concurrent and subsequent vocabulary comprehension and production was obtained at 14 and 18 months. The results indicated that the children who displayed a high interest and engagement in shared reading at 14 months had more advanced language skills 4 months later. Also found was support for a link between maternal strategies and children's subsequent vocabulary comprehension and production. In accordance with the literature, maternal activation was more strongly related to the children's language development than the mere describing of the elements in the book. No differences emerged between the NR and RD groups in the frequencies of maternal interactional behaviors, children's participation in shared reading, or their language skills at this early age; maternal orienting of the children's attention was, however, found to be positively related to later language development in the NR group, while in the RD group the association was negative. Copyright © 1999 John Wiley & Sons, Ltd.     

动作视频游戏对发展性阅读障碍者阅读技能的影响及其内在机制

发展性阅读障碍是一种在获得阅读技能方面的特殊困难, 这种障碍会严重影响个体的发展, 如何帮助发展性阅读障碍者改善其阅读技能是近年来研究的焦点。传统的干预方法主要针对发展性阅读障碍者的语音缺陷, 这类方法存在一些问题, 如费时费力、给阅读障碍者带来阅读压力等。近年来, 大部分研究表明通过趣味性的动作视频游戏训练可以显著地提高发展性阅读障碍者的阅读技能, 但是其背后的机制尚不明确。基于大细胞通路缺陷理论框架, 从视觉空间注意、注意跨通道转换、视觉运动加工等方面来梳理动作视频游戏与阅读之间的关系, 揭示了动作视频游戏训练对阅读效率影响的可能内在机制。未来的研究可以在大细胞通路缺陷理论的框架下, 深入分析动作视频游戏改善阅读的神经机制, 并尝试开发更适合发展性阅读障碍者的干预程序。     

Sad and happy emotion discrimination in music by children with cochlear implants

Children using cochlear implants (CIs) develop speech perception but have difficulty perceiving complex acoustic signals. Mode and tempo are the two components used to recognize emotion in music. Based on CI limitations, we hypothesized children using CIs would have impaired perception of mode cues relative to their normal hearing peers and would rely more heavily on tempo cues to distinguish happy from sad music. Study participants were children with 13 right CIs and 3 left CIs (M = 12.7, SD = 2.6 years) and 16 normal hearing peers. Participants judged 96 brief piano excerpts from the classical genre as happy or sad in a forced-choice task. Music was randomly presented with alterations of transposed mode, tempo, or both. When music was presented in original form, children using CIs discriminated between happy and sad music with accuracy well above chance levels (87.5%) but significantly below those with normal hearing (98%). The CI group primarily used tempo cues, whereas normal hearing children relied more on mode cues. Transposing both mode and tempo cues in the same musical excerpt obliterated cues to emotion for both groups. Children using CIs showed significantly slower response times across all conditions. Children using CIs use tempo cues to discriminate happy versus sad music reflecting a very different hearing strategy than their normal hearing peers. Slower reaction times by children using CIs indicate that they found the task more difficult and support the possibility that they require different strategies to process emotion in music than normal.     

The sound of motion in spoken language: visual information conveyed by acoustic properties of speech

Language is generally viewed as conveying information through symbols whose form is arbitrarily related to their meaning. This arbitrary relation is often assumed to also characterize the mental representations underlying language comprehension. We explore the idea that visuo-spatial information can be analogically conveyed through acoustic properties of speech and that such information is integrated into an analog perceptual representation as a natural part of comprehension. Listeners heard sentences describing objects, spoken at varying speaking rates. After each sentence, participants saw a picture of an object and judged whether it had been mentioned in the sentence. Participants were faster to recognize the object when motion implied by speaking rate matched the motion implied by the picture. Results suggest that visuo-spatial referential information can be analogically conveyed and represented.     

Procedural learning and automatization process in children with developmental coordination disorder and/or developmental dyslexia

ObjectiveThere is increasing evidence to suggest that developmental dyslexia (DD) and developmental coordination disorder (DCD) actually form part of a broader disorder. Their frequent association could be justified by a deficit of the procedural memory system, that subtends many of the cognitive, motor and linguistic abilities that are impaired in both DD and DCD. However, studies of procedural learning in these two disorders have yielded divergent results, and in any case no studies have so far addressed the issue of automatization (dual-task paradigm).MethodsWe administered a finger tapping task to participants aged 8–12 years (19 DCD, 18 DD, and 22 with both DD and DCD) to explore procedural learning and automatic movements in these three groups of children, comparing motor performances at the prelearning stage, after 2 weeks of training, and in a post-training dual-task condition.ResultsFirst, results indicated that all the children were able to learn a sequence of movements and even automatize their movements. Second, they revealed between-groups differences in procedural/automatization learning abilities, setting the DCD group apart from the other two. Third, contrary to our expectations concerning comorbidity, they suggested that the DD + DCD association does not have an additional impact on behavioral performances.     

Neural correlates of temporal auditory processing in developmental dyslexia during German vowel length discrimination: an fMRI study

This fMRI study investigated phonological vs. auditory temporal processing in developmental dyslexia by means of a German vowel length discrimination paradigm (Groth, Lachmann, Riecker, Muthmann, & Steinbrink, 2011). Behavioral and fMRI data were collected from dyslexics and controls while performing same-different judgments of vowel duration in two experimental conditions. In the temporal, but not in the phonological condition, hemodynamic brain activation was observed bilaterally within the anterior insular cortices in both groups and within the left inferior frontal gyrus (IFG) in controls, indicating that the left IFG and the anterior insular cortices are part of a neural network involved in temporal auditory processing. Group subtraction analyses did not demonstrate significant effects. However, in a subgroup analysis, participants performing low in the temporal condition (all dyslexic) showed decreased activation of the insular cortices and the left IFG, suggesting that this processing network might form the neural basis of temporal auditory processing deficits in dyslexia.     

维吾尔语发展性阅读障碍儿童的高频词词典通达

采用启动条件下的图片命名任务,比较维吾尔语发展性阅读障碍儿童和正常儿童高频词词典通达过程。结果发现：反应时上,正常组在SOA为60ms 时,出现了整词启动效应,而SOA为100ms时,出现了整词和音节启动效应;障碍组在不同启动条件下都没有出现启动效应;错误率上,障碍组出现了整词和音节干扰效应;正常组出现了整词促进效应;在所有启动条件下,障碍儿童的图片命名反应时都比正常儿童慢。结果说明,维吾尔语阅读障碍儿童由于其心理词典中高频词的形-音联结薄弱,而存在词典通达落后。