MORPHINE TOLERANCE AS A FUNCTION OF RATIO SCHEDULE: RESPONSE REQUIREMENT OR UNIT PRICE?

Key pecking by 3 pigeons was maintained by a multiple fixed-ratio 10, fixed-ratio 30, fixed-ratio 90 schedule of food presentation. Components differed with respect to amount of reinforcement, such that the unit price was 10 responses per 1-s access to food. Acute administration of morphine, l-methadone, and cocaine dose-dependently decreased overall response rates in each of the components. When a rate decreasing dose of morphine was administered daily, tolerance, as measured by an increase in the dose that reduced response rates to 50% of control (i.e., the ED50 value), developed in each of the components; however, the degree of tolerance was smallest in the fixed-ratio 90 component (i.e., the ED50 value increased the least). When the l-methadone dose-effect curve was redetermined during the chronic morphine phase, the degree of cross-tolerance conferred to l-methadone was similar across components, suggesting that behavioral variables may not influence the degree of cross-tolerance between opioids. During the chronic phase, the cocaine dose-effect curve shifted to the right for 2 pigeons and to the left for 1 pigeon, which is consistent with predictions based on the lack of pharmacological similarity between morphine and cocaine. When the morphine, l-methadone, and cocaine dose-effect curves were redetermined after chronic morphine administration ended, the morphine and l-methadone ED50s replicated those obtained prior to chronic morphine administration. The morphine data suggest that the fixed-ratio value (i.e., the absolute output) determines the degree of tolerance and not the unit price.     

MEMORY PROCESSES IN DELAYED SPATIAL DISCRIMINATIONS: RESPONSE INTENTIONS OR RESPONSE MEDIATION?

Pigeons were trained on a pair-comparison task in which left versus right choices were reinforced following different sequences of two center-key stimuli. Choice accuracy was higher when retention intervals occurred after the entire sequence than when they separated the two stimuli comprising it, and this effect occurred independently of whether the initial and terminal stimuli came from the same or different dimensions. The initial stimulus from the prior trial was a source of proactive interference only in groups for which the retention interval separated the two sequence stimuli. By contrast, differential delay-interval behavior was observed only in groups for which the retention interval followed presentation of the entire sequence. These results indicate that coding processes in delayed discriminations are influenced by the location of the retention interval, and that response mediation affects retention performances if the reinforced choice can be determined prior to the interval.     

A ROLE FOR NEGATIVE REINFORCEMENT OF RESPONSE OMISSION IN PUNISHMENT?

This experiment attempted to disentangle response-rate reductions controlled by the direct suppressive effects of a punisher from those due to negative reinforcement of response omission. Key-peck responding of pigeons was maintained by a conjoint variable-interval 3-min schedule of food presentation variable-interval 30-s schedule of response-dependent electric shock presentation. Omission of responses for 5, 10, or 30 s resulted in the possibility of canceling a scheduled shock. Response rates were a function of required pause duration, with lower rates occurring when longer periods of response omission were required for shock cancellation. These results show that, with several parameters of punishment held constant, response rates were controlled by the negative reinforcement contingency. Such a finding argues for renewed consideration of the role of negative reinforcement in punishment contingencies.     

WHY PRACTICE PHILOSOPHY AS A WAY OF LIFE?

This essay explains why there are good reasons to practice philosophy as a way of life. The argument begins with the assumption that we should live well but that our understanding of how to live well can be mistaken. Philosophical reason and reflection can help correct these mistakes. Nonetheless, the evidence suggests that philosophical reasoning often fails to change our dispositions and behavior. Drawing on the work of Pierre Hadot, the essay claims that spiritual exercises and communal engagement mitigate the factors that prevent us from living in accordance with our conceptions of the good life. So, many of us have reasons to engage in philosophical reasoning along with behavioral, cognitive, and social strategies to alter our behavior and attitudes so that they’re in line with our philosophical commitments. In these respects, many of us should practice philosophy as a way of life.     

KUZGUNCUK AS A VILLAGE OF MUTUAL RESPECT AND HARMONY: MYTH OR REALITY?

My research concentrates on the Jews of Istanbul and especially on the Kuzguncuk neighbourhood. My aim is to understand the changes within the social structure of the Jewish community of Turkey and its relationship with the dominant Muslim society. Different from other important Jewish neighbourhoods of Istanbul such as quarters in Balat, Haskoy and Galata-Pera district, Kuzguncuk is known as the “village of harmony” and a “place in which all religious and ethnic groups live in peace, harmony and mutual respect”. In this article, I try to answer the question of whether this is a myth or the real experience of Kuzguncuk. Whether a myth or a real experience, can it be a model for people “living together in peace and harmony”? I will also explore the situation of Jews after the foundation of the Turkish republic. In order to understand the changing structure of Jews of Kuzguncuk, I conducted interviews with seven actual and former residents of Kuzguncuk, who now live in Israel, Kuzguncuk and other districts of Istanbul.     

LEIBNIZ’S PHILOSOPHY AS A WAY OF LIFE?

The main concern of this essay is to make a case for the thesis that Leibniz conceived of his philosophy as a way of life in something like the sense articulated in the works of Pierre Hadot. On this view, philosophy was a type of conduct, or a mode of existing-in-the-world, which had to be practised at each instant, with the goal of transforming the whole of the individual’s life. The essay also serves as an introduction to some of the main themes in Hadot’s work. While it includes a brief discussion of a number of the central components of Leibniz’s philosophy conceived as a way of life, the essay does not aim to do so in great detail. Rather, it offers a manifesto and initial road map.     

SEARCHING FOR HOUSING AS A BATTERED WOMAN: DOES DISCRIMINATION AFFECT REPORTED AVAILABILITY OF A RENTAL UNIT?

Individual battered women have reported experiencing housing discrimination, but the extent of this problem has not been examined. This research used two experiments and a survey to determine if landlord discrimination could keep women from accessing rental units. In Study 1, a confederate asked 181 landlords about the availability of a rental unit in one of three living conditions (shelter, friends, no mention of current living conditions) and across two scenarios (does or does not have a child). Rental units were almost 10 times more likely to be available in the control condition compared to the shelter condition, χ²(1,  N  = 181) = 8.624,  p  = .003, and these results were not affected by whether or not the caller had a child, χ²(1,  N  = 181) = 0.214,  p  = .644. In Study 2, the confederate was employed and left a message on 92 landlords' answering machines in the same three living conditions. The hypothesized comparison between the shelter and the other two conditions combined was significant, χ²(1,  N  = 92) = 4.602,  p  = .032. Finally, in a telephone survey of 31 landlords, a substantial minority (23%) said they would not rent to a hypothetical battered woman. The results of our studies suggest that discrimination against battered women by landlords is a real problem that is likely contributing to the difficulties that women experience in finding safe and affordable long-term housing.     

UNIVERSAL HUMAN RIGHTS AS A SHARED POLITICAL IDENTITY IMPOSSIBLE? NECESSARY? SUFFICIENT?

Abstract: Would a global commitment to international human rights norms provide enough of a sense of community to sustain a legitimate and sufficiently democratic global order? Sceptics worry that human rights cannot help maintain the mutual trust among citizens required for a legitimate political order, since such rights are now too broadly shared. Thus prominent contributors to democratic theory insist that the members of the citizenry must share some features unique to them, to the exclusion of others—be it a European identity ( Habermas and Derrida 2003 ) or a national public culture generally shared only by the members ( Miller 1995, 2000 ). This essay considers and rejects these arguments. While stable, democratic redistributive arrangements do require trust and institutionalised means of trustworthiness; they need not rely on norms or values that distinguish members from non-members: such exclusion is not required. Thus human rights may be part of a common political identity.     

LINNAEUS AS A SECOND ADAM? TAXONOMY AND THE RELIGIOUS VOCATION

Swedish naturalist Carl von Linné (1707–1778) became known during his lifetime as a “second Adam” because of his taxonomic endeavors. The significance of this epithet was that in Genesis Adam was reported to have named the beasts—an episode that was usually interpreted to mean that Adam possessed a scientific knowledge of nature and a perfect taxonomy. Linnaeus's soubriquet exemplifies the way in which the Genesis narratives of creation were used in the early modern period to give religious legitimacy to scientific activities and to taxonomy in particular. Allusions to Adam's work in the Garden of Eden thus became a way of investing the vocation of the naturalist with religious significance.     

REPEATED ACQUISITION OF BEHAVIORAL CHAINS: RESPONSE SEQUENCES OR CONDITIONAL DISCRIMINATIONS?

The purpose of this study was to determine whether pigeons learn a sequence of positional responses or a series of conditional discriminations under a repeated-acquisition-of-behavioral-chains procedure. Three pigeons were trained under a repeated-acquisition procedure in which three different key colors served as stimuli correlated with the three steps in a chain. The order of presentation of the three stimuli was altered during the latter part of each test session after acquisition had occurred. If the pigeons had acquired a response sequence, the pattern of responding should remain the same as in the initial portion of the test session. However, if the pigeons had acquired a conditional discrimination, the response pattern should change in accordance with the changed order of the key colors. Although the results of this study do not rule out the possibility that the subjects acquired, to some degree, a response sequence, the results suggest that the behavior of pigeons under a repeated-acquisition-of-behavioral-chains procedure is controlled primarily by conditional discriminative stimuli.     

PRIMATES AND RELIGION: A BIOLOGICAL ANTHROPOLOGIST'S RESPONSE TO J. WENTZEL VAN HUYSSTEEN'S ALONE IN THE WORLD?

For a biological anthropologist interested in the prehistory of religion, J. Wentzel van Huyssteen's book is welcome and resonant. Van Huyssteen's central thesis is that humans' capacity for spirituality emerges from a transformation of cognition and emotions that takes place in the symbolic realm, within Homo sapiens and apart from biology. To his thesis I bring to bear three areas of response: the abundant cognitive and emotional capacities of living apes and extinct hominids; the role of symbolic ritual in the evolutionary history of Homo sapiens; and the closely intertwined nature of biology and culture in the workings of evolutionary change.     

CUI BONO? A REVIEW OF BREAKING THE SPELL: RELIGION AS A NATURAL PHENOMENON BY DANIEL C. DENNETT

The three requirements for a Darwinian evolutionary process are replication, variation and selection. Dennett (2006) discusses various theories of how these three processes, especially selection, may have operated in the evolution of religion. He believes that the origins of religion, like the origins of language and music, may be approached scientifically. He hopes that such investigations will open a dialog between science and religion leading to moderation of current religious extremism. One problem with Dennett's program, illustrating the difficulty of breaking away from creationist thinking, is Dennett's own failure to consider how Darwinian methods may be used to study evolution of behavioral patterns over the lifetime of individual organisms.