From Validating to Verifying: Public Appeals in Synthetic Biology

Synthetic biology provides a vivid and richly entangled contemporary example of a science being made public. A science, however, can be made public in different ways. A public could validate, legitimate, de-legimate, object to, verify, confirm or dissent from science. Practically, scientists could publicise science—in the mass media—or they could make science public. The contrast between high-profile, media scientists such as J. Craig Venter, and community-based participatory mechanisms such as OpenWetWare allows us to see how these alternatives play out in practice. While it is easy to criticise and dismiss the public-relations oriented promotion of synthetic biology by figures such as Venter, how should we evaluate the open participatory mechanisms of a social media effort such as OpenWetWare? I suggest, drawing on the work of Isabelle Stengers and Michael Warner, that the case of synthetic biology is interesting because many synthetic biologists commit themselves to making it public, and making its public-ness part of how it is done. They place hope in publics to make the science viable. At the same time, however, the publics who are welcomed into OpenWetWare are largely confined to validating the coordination mechanisms on which the claim to public-ness rests. Whether publics can do more than validate synthetic biology, then, remains a question both for publics outside and inside this emerging scientific field. And whether the alternatives of validation or participation themselves adequately frame what is at stake in the emergence of fields such as synthetic biology remains debatable.     

Use It or Lose It: Post-workshop Reflection Enhances Learning and Utilization of CBT Skills

Many therapists attend 1- or 2-day workshops as part of their continuing professional development. Recent literature has suggested that workshops are largely ineffective unless followed up by consultation or supervision. However, not all therapists have this option, and the question remains whether there are ways to potentiate workshop learning in the absence of follow-up consultation. This study tested the hypothesis that creating opportunities to reflect in the weeks following a workshop would enhance learning and utilization of skills. Two groups of practitioners, who attended the same 2-day CBT skills workshop in successive years, were compared: a training-as-usual group and a reflection group. The reflection group completed reflection worksheets at the end of each workshop day and were instructed to complete follow-up reflection worksheets at 1, 4 and 8 weeks post-workshop. Ten weeks after the workshop, the reflection group reported enhanced use of new skills with clients and a trend towards increased awareness of workshop learning. Further analysis revealed that group differences were almost entirely linked to use of follow-up reflection worksheets. Those participants in the reflection group who used follow-up reflection worksheets reported far greater awareness and use of skills than those who did not. Reminder emails had the predicted effect of increasing the use of the reflection worksheets; twice as many participants in the email reminder group used the reflection sheets compared with the nonreminder group. The results suggest that the relatively simple strategy of introducing reflection worksheets to workshop handouts, and sending reminder emails may significantly enhanced learning and utilization of workshop skills.     

Non-Naturalist Moral Realism and the Limits of Rational Reflection

This essay develops the epistemic challenge to non-naturalist moral realism. While evolutionary considerations do not support the strongest claims made by ‘debunkers’, they do provide the basis for an inductive argument that our moral dispositions and starting beliefs are at best partially reliable. So, we need some method for separating truth from falsity. Many non-naturalists think that rational reflection can play this role. But rational reflection cannot be expected to bring us to truth even from reasonably accurate starting points. Reflection selects views that are coherent and conflict-free, yet there is no reason to think that the non-natural moral truth must be like this. Inasmuch as we seek coherent, conflict-free, ethical viewpoints, that suggests that our goal is not non-natural truth at all.     

Embodied Reflection in Mindfulness-Based Cognitive Therapy for Depression

The prime objective of this study was to explore an initial operationalization of embodied reflection in mindfulness-based cognitive therapy (MBCT). The concept of embodied reflection, derived from a phenomenological frame of reference, is presented. The implications of an embodied reflection perspective for understanding how body awareness in MBCT fosters therapeutic change are discussed. This article presents the results of a small-scale exploratory qualitative study illustrating processes of embodied reflection for different subgroups of MBCT participants. The analysis suggests that different subgroups are able to harness body awareness in different ways depending on their precourse strategy for avoiding emotional experience. It is proposed that further exploration and refinement of the processes of embodied reflection will enhance clinical practice and treatment outcomes.     

Tree thinking: a new paradigm for integrating comparative data in psychology

Over the past 15 years, several important theoretical and methodological developments have emerged from evolutionary biology. These developments--collectively dubbed tree thinking--are now well known in evolutionary biology but have yet to be incorporated into mainstream psychology. Tree thinking has revolutionized evolutionary biology and has the potential to do the same for how comparative data are integrated into psychology. Tree thinking holds that explanations (or narratives) for adaptations must be based on an understanding of the adaptations' history (or chronicle) over evolutionary time. This tenet of tree thinking requires researchers to consider hitherto neglected patterns of data. The authors present the ideas and methods behind tree thinking, examining their implications for psychology.     

Beyond Patchwork Precaution in the Dual-Use Governance of Synthetic Biology

The emergence of synthetic biology holds the potential of a major breakthrough in the life sciences by transforming biology into a predictive science. The dual-use characteristics of similar breakthroughs during the twentieth century have led to the application of benignly intended research in e.g. virology, bacteriology and aerobiology in offensive biological weapons programmes. Against this background the article raises the question whether the precautionary governance of synthetic biology can aid in preventing this techno-science witnessing the same fate? In order to address this question, this paper proceeds in four steps: it firstly introduces the emerging techno-science of synthetic biology and presents some of its potential beneficial applications. It secondly analyses contributions to the bioethical discourse on synthetic biology as well as precautionary reasoning and its application to life science research in general and synthetic biology more specifically. The paper then identifies manifestations of a moderate precautionary principle in the emerging synthetic biology dual-use governance discourse. Using a dual-use governance matrix as heuristic device to analyse some of the proposed measures, it concludes that the identified measures can best be described as “patchwork precaution” and that a more systematic approach to construct a web of dual-use precaution for synthetic biology is needed in order to guard more effectively against the field’s future misuse for harmful applications.     

‘When Difference Gets in the Way’: Young People,Whiteness and Sexualisation

Scholars of young people and sexualisation have noted an omission of studies that attend to race and whiteness. In the main, a white-Anglo middle-class child is placed at the centre of media, policy and academic debates about the effects, production and consumption of sexualised media. In light of this, it is important to ask: how can research in this area disrupt the tendency to place normative white subjects at the centre of debates, and position ‘raced others’ at the sidelines? Drawing on postcolonial and critical race and whiteness theory, this paper presents the findings from a study undertaken in South Australia with young people and young adults from a broad variety of cultural backgrounds. Through a series of focus groups designed to explore participant views of sexualised media, a powerful set of resistant narratives emerged. Firstly, participants discussed how their views on sex and sexuality are often read ‘through difference’. They revealed how ‘difference gets in the way’, frustrating conversations they want to have about sexy media, along with moments when they felt stereo-typed and type-cased. Secondly, by presenting perspectives of sexualised media on their own terms, participant narratives were not constrained or bounded by fixed cultural viewpoints. Through a series of ‘transitional moves’, participants employed notions of freedom, individual choice and rights, expressing an urgent desire to speak ‘outside of difference’.     

Spatial Updating Strategy Affects the Reference Frame in Path Integration

This study investigated how spatial updating strategies affected the selection of reference frames in path integration. Participants walked an outbound path consisting of three successive waypoints in a featureless environment and then pointed to the first waypoint. We manipulated the alignment of participants’ final heading at the end of the outbound path with their initial heading to examine the adopted reference frame. We assumed that the initial heading defined the principal reference direction in an allocentric reference frame. In Experiment 1, participants were instructed to use a configural updating strategy and to monitor the shape of the outbound path while they walked it. Pointing performance was best when the final heading was aligned with the initial heading, indicating the use of an allocentric reference frame. In Experiment 2, participants were instructed to use a continuous updating strategy and to keep track of the location of the first waypoint while walking the outbound path. Pointing performance was equivalent regardless of the alignment between the final and the initial headings, indicating the use of an egocentric reference frame. These results confirmed that people could employ different spatial updating strategies in path integration (Wiener, Berthoz, & Wolbers Experimental Brain Research 208(1) 61–71, 2011), and suggested that these strategies could affect the selection of the reference frame for path integration.     

Sex Workers and HIV/AIDS: Analyzing Participatory Culture‐Centered Health Communication Strategies

An emerging trend in health communication research advocates the need to foreground articulations of health by participants who are at the core of any health campaign. Scholarly work suggests that the culture‐centered approach to health communication can provide a theoretical and practical framework to achieve this objective. The culture‐centered approach calls for attention to dialogue and locates the agency of cultural participants in the culture being studied. This approach underlines the import of participation of community members in the enunciation of health problems as a step toward achieving meaningful change. Based on the culture‐centered approach, this article examines narratives of sex workers to analyze how participatory communicative strategies frame discourses and practices of health, particularly those related to HIV/AIDS.     

Locating Responsible Research and Innovation Within Access and Benefit Sharing Spaces of the Convention on Biological Diversity: the Challenge of Emerging Technologies

This paper reviews the location of Responsible Research and Innovation (RRI) approaches within the access and benefit sharing (ABS) policy spaces of the Convention on Biological Diversity (CBD) and Nagoya Protocol. We describe how a range of dialogues on ethical research practices found a home, almost inadvertently, within the ABS policy process. However, more recent RRI dialogues around emerging technologies have not been similarly absorbed into ABS policy, due in part to the original framing of ABS and associated definitional and scope issues. Consideration is given to the challenges posed to these policy processes by the transformative and rapid nature of scientific and technological change today, including the emerging field of synthetic biology. Drawing on experiences from regulating ABS, we emphasize that the integration of RRI into policies for new, emerging, or poorly understood activities such as synthetic biology faces deficiencies such as limits to government capacity, jurisdictional confusion, shortages in funds, and an absence of strategic approaches. We conclude that a coordinated combination of diverse policy processes within the CBD might provide an invaluable space for RRI dialogues on social justice, sustainability, biosafety, and other issues raised by emerging technologies.     

When Reflection Hinders Creative Problem-Solving: a Test of Alternative Reflection Strategies

A growing body of evidence suggests that reflecting on performance is an important source of individual learning. Given the importance of creativity in contemporary business settings, reflection has also been cast as a useful strategy to facilitate creative problem-solving. Challenging this idea, we conducted a series of lab experiments to examine the effects of reflection on creative problem-solving. Drawing from theory in cognitive psychology on knowledge structures, we argue that reflection may sometimes debilitate rather than improve creative problem-solving, due to the reinforcement of existing cognitive schemas and the resulting cognitive entrenchment. To test our theoretical arguments, we developed two alternative reflection strategies, imaginative reflection and vicarious elaboration. In Study 1 (N = 101), we observed a detrimental effect of task reflection on creative problem-solving, which was offset by having participants engage in imaginative reflection. In Study 2 (N = 191), vicarious elaboration, elaborating on another’s creative experiences instead of reflecting on one’s own creative experiences, was introduced as a second strategy to counter cognitive entrenchment. In Study 3 (N = 235), we combined the reflection strategies, demonstrating that imaginative thinking was more effective when focused on one’s own experiences rather than on others’ experiences (i.e., vicarious imaginative elaboration). Together, these findings increase our understanding of the effects of different reflection strategies, but also call for further research to address an intriguing observation: none of the reflection strategies led to better outcomes as compared to a control condition without reflection, suggesting that individual reflection might not help creative problem-solving at all.

     

Predictors of Dropout in Cognitive Processing Therapy for PTSD: An Examination of Trauma Narrative Content

Dropout rates in trauma-focused treatments for adult posttraumatic stress disorder (PTSD) are high. Most research has focused on demographic and pretreatment predictors of dropout, but findings have been inconsistent. We examined predictors of dropout in cognitive processing therapy (CPT) by coding the content of trauma narratives written in early sessions of CPT. Data are from a randomized controlled noninferiority trial of CPT and written exposure therapy (WET) in which CPT showed significantly higher dropout rates than WET (39.7% CPT vs. 6.4% WET). Participants were 51 adults with a primary diagnosis of PTSD who were receiving CPT and completed at least one of three narratives in the early sessions of CPT. Sixteen (31%) in this subsample were classified as dropouts and 35 as completers. An additional 9 participants dropped out but could not be included because they did not complete any narratives. Of the 11 participants who provided a reason for dropout, 82% reported that CPT was too distressing. The CHANGE coding system was used to code narratives for pathological trauma responses (cognitions, emotions, physiological responses) and maladaptive modes of processing (avoidance, ruminative processing, overgeneralization), each on a scale from 0 (absent) to 3 (high). Binary logistic regressions showed that, averaging across all available narratives, more negative emotions described during or around the time of the trauma predicted less dropout. More ruminative processing in the present time frame predicted lower rates of dropout, whereas more overgeneralized beliefs predicted higher rates. In the first impact statement alone, more negative emotions in the present time frame predicted lower dropout rates, but when emotional reactions had a physiological impact, dropout was higher. These findings suggest clinicians might attend to clients’ written trauma narratives in CPT in order to identify indicators of dropout risk and to help increase engagement.     

Through Solidarity to “Fluidarity”: Understanding Difference and Developing Change Agency Through Narrative Reflection

This paper examines the development of the concept of solidarity as expressing a sense of shared humanity, while detailing critiques of its current use, especially when it implies a privileged center setting the agenda for the sake of marginalized others. My research demonstrates how solidarity can be modified when encountering difference, and how it might be better conceptualized as “fluidarity,” an attitude and practice that embraces the complexity of engaging the other in pluralized and ever‐changing struggles. This engagement with otherness, an explicit part of an undergraduate theological ethics course with an embedded service‐learning component, is pedagogically facilitated by a threefold reflection process required of students: critical reflection on their own narratives, reflection on the narratives encountered in their service‐learning, and reflection on the lives of spiritually grounded agents of social change. Case studies of four undergraduate students demonstrate the ways in which this pedagogical strategy contributes to the development of solidarity and moves students' understanding towards fluidarity. In the end, the students gained a sense of spiritually grounded change agency, combining spiritual development with growth in critical consciousness.     

The integration of spatial information across different viewpoints

The integration of spatial information perceived from different viewpoints is a frequent, yet largely unexplored, cognitive ability. In two experiments, participants saw two presentations, each consisting of three targets—that is, illuminated tiles on the floor—before walking the shortest possible path across all targets. In Experiment 1, participants viewed the targets either from the same viewpoint or from different viewpoints. Errors in recalling targets increased if participants changed their viewpoints between presentations, suggesting that memory acquired from different viewpoints had to be aligned for integration. Furthermore, the error pattern indicates that memory for the first presentation was transformed into the reference frame of the second presentation. In Experiment 2, we examined whether this transformation occurred because new information was integrated already during encoding or because memorized information was integrated when required. Results suggest that the latter is the case. This might serve as a strategy for avoiding additional alignments.     

空间场景表征中的参照系选取

被试在矩形房间中从两个不同的观察点学习物体场景并在多个朝向上对物体形成的空间关系进行判断,通过控制场景中物体主要内在轴相对于环境结构（房间和地毯）的方向和被试的学习顺序,探讨被试在场景空间表征中采用何种参照系和参照系选取时的影响因素。两个实验结果发现：（1）内在参照系（intrinsic reference systems）和环境参照系均可以用于物体场景的表征,两类参照系之间的关系却是影响被试物体场景表征时参照系选取的重要因素,即当内在参照系与环境参照系方向一致时,被试无论从哪个朝向学习,都选择从垂直于内在参照系和环境参照系的朝向进行表征。反之,当二者方向不一致时,表征时参照系的选择取决于被试的学习经历;（2）无论内在参照系与环境参照系方向是否一致,物体场景本身内在结构的规则性都能够促进空间记忆,即内在结构的规则性既有助于准确编码物体的相对位置,也有助于提高空间关系判断的准确性。     

Medical Students’ Efforts to Integrate and/or Reclaim Authentic Identity: Insights from a Mask-Making Exercise

Medical students’ mask-making can provide valuable insights into personal and professional identity formation and wellness. A subset of first- and second-year medical students attending a medical school wellness retreat participated in a mask-making workshop. Faculty-student teams examined student masks and explanatory narratives using visual and textual analysis techniques. A quantitative survey assessed student perceptions of the experience. We identified an overarching theme: “Reconciliation/reclamation of authentic identity.” The combination of nonverbal mask-making and narrative offers rich insights into medical students’ experience and thinking. This activity promoted reflection and self-care, while providing insight regarding personal and professional development.     

Reflecting on how we remember the personal past: missing components in the study of memory appraisal and theoretical implications

The current paper offers a selective review of the study of memory appraisal, focusing on recollections of the personal past, with the goal to bring attention to a missing component in this study. To date, memory appraisal studies have concentrated on participants’ assessments of the content of their personal recollections (e.g., their perceptual detail and story-like feel), including beliefs about the accuracy of that content. Participants’ assessments of reflection processes accompanying their recollections (e.g., a sense of piecing-together recollection fragments) have yet to be extensively examined. The lack of information on process-based appraisals is related to prior studies’ procedural constraints (e.g., kinds of cue prompts and their timing, minimal opportunities for reflection). Reasons for addressing this missing component provide the central themes of the paper. The reasons emerge from the analysis of autobiographical cueing studies, including integration of narrative research studies and autobiographical works. The analysis leads to suggestions for future research involving the use of personal narratives that are intended to address critiques of reconstruction accounts and unresolved questions in the study of memory appraisal.     

Using Historical Knowledge to Reason About Contemporary Political Issues: An Expert–Novice Study

People often justify history's place in the curriculum by its relationship to citizenship, yet there is little research to help educators picture how people use historical knowledge for civic purposes. This expert–novice study used the think-aloud method to examine how eight political scientists and eight high school students employed historical knowledge to reason about a political issue. Findings indicated that detailed historical narrative played an important role for experts’ reasoning, and the experts used narrative to frame the issue, support their positions, and evaluate historical claims. Participating students used narrative as well, but their narratives were lacking in detail. They never used history to frame the problem, contextualize documents, or to support their positions, and they rarely used narrative to evaluate claims. These differences in how experts and novices use history to make sense of the present have implications for history instruction and research in history and civic education.     

目标数量与运动框架旋转角度对不同场认知风格个体多目标追踪表现的影响

通过改变目标数量、运动框架突变旋转角度探究不同场认知风格被试在多目标追踪任务中的表现。结果发现：(1)在任务难度较低(运动参考框架稳定, 目标数量为3和4)和任务难度中等(运动参考框架突变向右旋转20°, 目标数量为4)条件下, 场独立型被试的多目标追踪表现均显著好于场依存型被试。在任务难度较高(运动框架稳定, 目标数量为5以及运动参考框架突变向右旋转40°, 目标数量为4)条件下, 两组被试差异不显著。表明不同场认知风格被试追踪表现受任务难度影响; (2)随着目标数量由3至5增多, 追踪负荷增大使被试的追踪成绩显著下降; (3)相比运动框架稳定, 运动框架向右突变旋转20°和40°均显著削弱了被试的追踪表现。旋转角度变化破坏了场景连续性, 影响了追踪表现。     

Community Involvement and Narrative Identity in Emerging and Young Adulthood: A Longitudinal Analysis

This study examines community engagement in youth and emerging adulthood from a narrative identity perspective, based on analyses of a longitudinal data set of 72 participants from ages 17 to 32. At ages 26 and 32, participants told narratives about a key community experience from their personal lives, which was rated for six dimensions. In addition, questionnaire measures of community involvement and general identity status development were administered at ages 17, 26, and 32. We found that patterns of community involvement at age 17 predicted levels of community involvement and qualities of community narratives at ages 26 and 32 and that community narratives were significantly correlated with concurrent measures of identity maturity and community involvement. Limitations and implications for future research are discussed.