Effects of tobacco smoking on electroencephalographic, auditory evoked and event related potentials

After overnight abstinence, tobacco smokers smoked an average nicotine yield cigarette and nonsmokers sham smoked an unlit placebo cigarette. EEG alpha(1), delta, and theta frequency amplitudes decreased, whereas alpha(2) and beta frequency amplitude increased. Short, middle (EP) and long latency ERP were also studied in nonsmokers and smokers just after smoking, and after overnight abstinence from tobacco. Short latency potentials were unaffected by tobacco smoking or abstinence. Middle and long-latency potentials were reduced during abstinence and enhanced immediately after tobacco smoking. These findings indicate that compared to nonsmokers smokers have a higher arousal level after smoking than when partially abstinent. Evidence for both normalization from tobacco abstinence as well as stimulation was obtained.     

Perceived Believability Among Adolescents of Health Warning Labels on Cigarette Packs1

This study investigated the extent to which adolescents believe the health warning labels on cigarette packs, and the relationship of current smoking status and gender to the believability ratings. Subjects were 691 students in grades 5 through 12. MANOVAs revealed that, smokers, both male and female, reported significantly less belief in the validity of 3 of the health warning labels than nonsmokers. These findings support prior investigations which indicate that adolescent smokers are less likely to accept the specific health risks associated with smoking than nonsmokers. The results, however, also raise the question as to what value such health warning labels have as a deterrent to cigarette smoking.     

Implicit alcohol and smoking associations among young adult heavy drinkers: Associations with smoking status and alcohol-cigarette co-use

Implicit memory associations may play a role in motivation to use alcohol and cigarettes, but the relationship between implicit associations and co-use of alcohol and cigarettes is currently unknown. This study provided an initial examination of alcohol and smoking implicit associations among young adult drinkers who were either nonsmokers or relatively light smokers (i.e., 10 or fewer cigarettes per day) as a function of smoking frequency and daily-level alcohol-cigarette co-use. Drinkers (n?=?129) completed alcohol-arousal and smoking-valence variants of the implicit association test as well as a daily-level assessment of past 90-day alcohol and cigarette use. Smokers were grouped according to whether they reported daily or nondaily smoking frequency. Results showed that although implicit alcohol-arousal associations did not differ between smokers and nonsmokers, stronger implicit alcohol-arousal associations were observed for nondaily smokers relative to daily smokers after controlling for drinking frequency. Further, implicit positive-smoking associations were stronger for smokers relative to nonsmokers. Within the subgroup of nondaily smokers, more frequent co-use of alcohol and cigarettes was associated with stronger implicit positive-smoking associations when controlling for total drinking and smoking frequency. The findings suggest that implicit alcohol and smoking associations may be linked with smoking patterns (daily vs. nondaily) and co-use of alcohol and cigarettes among young adult drinkers who are not heavy smokers, highlighting the need for more research on the role of implicit associations in the co-use of cigarettes and alcohol.     

A note on responses to ethyl alcohol before and after smoking1

Differential sensitivity was measured before and after smoking a cigarette by 10 smokers, using 10 nonsmokers as controls. Stimuli consisted of reagent grade ethanol in eight concentrations ranging from 4% to 12%. No significant differences were observed between smokers and nonsmokers or before vs after smoking, although slightly higher overall correct responses and correspondingly smaller jnds were obtained for the nonsmokers. No practice affects were noted among the control group between the first and second set of samples. The findings confirm previous results which had been recently questioned.     

Adolescent Personality Antecedents of Adult Cigarette Smoking: A Longitudinal Study

Comprehensive personality assessments, made independently for early and late adolescence, were employed to predict smoking onset and maximum number of cigarettes smoked per day as reported by adult smokers. Also, comparisons were made between adult smokers and nonsmokers. The results indicate that men who had been more sexually active as adolescents smoked more but that women who had been more emotionally constricted and under more conflict as adolescents were heavier smokers. Smoking started earlier for men who had showed little self-awareness and a rather macho orientation during their adolescence; early-smoking women tended to have been conventionally feminine. Personality differences between future smokers and nonsmokers were few but showed similar sex differences. The results suggest that manifesting once traditional sex-role characteristics for both adolescent boys and girls presages early onset and heavier adult cigarette smoking. Preventive antismoking educational campaigns aimed at youth might be guided by these findings because they suggest some motivational bases that may find later expression in smoking practices.     

Adolescent personality antecedents of adult cigarette smoking: a longitudinal study

Comprehensive personality assessments, made independently for early and late adolescence, were employed to predict smoking onset and maximum number of cigarettes smoked per day as reported by adult smokers. Also, comparisons were made between adult smokers and nonsmokers. The results indicate that men who had been more sexually active as adolescents smoked more but that women who had been more emotionally constricted and under more conflict as adolescents were heavier smokers. Smoking started earlier for men who had showed little self-awareness and a rather macho orientation during their adolescence; early-smoking women tended to have been conventionally feminine. Personality differences between future smokers and nonsmokers were few but showed similar sex differences. The results suggest that manifesting once traditional sex-role characteristics for both adolescent boys and girls presages early onset and heavier adult cigarette smoking. Preventive antismoking educational campaigns aimed at youth might be guided by these findings because they suggest some motivational bases that may find later expression in smoking practices.     

Prevalence of cigarette smoking in Iran.

The current research assessed the prevalence of cigarette smoking in Shiraz, Iran by randomly selecting 1,335 subjects (782 men and 553 women) from the city for a face-to-face interview and completion of a questionnaire. Of the participants, 205 (26%) of the men and 20 (3.6%) of the women reported being current smokers. The mean ages of smokers and nonsmokers were 41.8 and 37.0 yr., respectively (range between 16 and 90 years for smokers and nonsmokers). The mean age of starting to smoke cigarettes was 21.3 yr. (range of 10 to 60). The most common reasons for current cigarette smoking were Need to avoid withdrawal symptoms, Release of tension, and Pleasurable purposes. Foreign filter-tipped cigarettes were the most common type consumed. The mean number of cigarettes per day was 13.4 (SD = 10.3). Reports for onset of cigarette smoking included Modeling, Release of tension, and Pleasurable purposes. Cigarette smoking was reported by more males than females. The most common reason for onset of cigarette smoking was different from that for current smoking. Frequencies of smokers within age groups were varied.     

Cigarette smokers do more than just smoke cigarettes

In this study, we hypothesized that light and moderate-to-heavy cigarette smokers, when compared with nonsmokers, would exhibit significantly less healthy attitudes and behaviors on several dimensions relevant to the risk of coronary heart disease (CHD). A factor analysis of survey items measuring knowledge, attitudes, and behaviors in five CHD risk areas produced four major factors, which we labeled Attitudes (Factor 1), Health Consciousness (Factor 2), Knowledge (Factor 3), and Unhealthy Behaviors (Factor 4). Factor-based scales generated for each of these four factors were used in a one-way multivariate analysis of variance to examine differences between nonsmokers, light smokers, and moderate-to-heavy smokers. Cigarette smokers versus nonsmokers exhibited less positive attitudes toward CHD risk behaviors, whereas moderate-to-heavy cigarette smokers, as compared with the light smokers and the nonsmokers, exhibited lower levels of health consciousness and enacted unhealthy behaviors at a greater frequency. The moderate-to-heavy cigarette smokers also exhibited a lower commitment to enact healthy behavioral changes in the immediate future, even after corrections were introduced for their lower frequency of healthy behaviors during the past week. Overall, these results support our hypothesis that cigarette smokers, particularly as they become more involved with cigarette smoking, do more than just smoke cigarettes; they exhibit a less healthy lifestyle as shown by cognitive, behavioral, and motivational dimensions related to cardiovascular health.     

The Aura of Tobacco Smoke: Cigars and Cigarettes as Image Makers

Male and female college undergraduates evaluated the character traits of men and women who were seen smoking cigars, smoking cigarettes, or not smoking. The evaluated adults were about 10 years older than the students. Irrespective of the evaluated persons' gender, ratings of appeal were specific to the gender of the evaluator. Men and women agreed in their perception of cigarette smokers as being less appealing than nonsmokers. However, whereas men ascribed markedly less appeal to cigar smokers than to cigarette smokers, women perceived cigar smokers as being as appealing as nonsmokers. This pattern was observed for all positive aspects of appeal; the inverse pattern was apparent for all negative aspects of appeal. In contrast, men and women concurred in judging cigar smokers as being more confident and secure than either nonsmokers or cigarette smokers.     

Residual effects of cigarette smoking on cognitive performance in normal aging

The present study examined the residual effects of smoking status on cognitive function in 76 nondemented older adults. Current smokers, ex-smokers, and nonsmokers who were screened for health and intellectual impairments were administered a battery of standardized neuropsychological tests to measure problem solving, psychomotor speed, memory, attention span, perception, and language production. Performance decrements were found for smokers on measures of psychomotor speed. No between-group differences were noted on any of the nonspeeded tests. There were no differences between nonsmokers and ex-smokers on any measures. The results suggest that the residual effects of current cigarette smoking negatively influence speeded cognitive capabilities in older adults.     

The acute effects of nicotine on positive and negative affect in adolescent smokers

Although adolescent cigarette smoking remains a critical public health concern, little is known about the reinforcing mechanisms governing smoking in this vulnerable population. To assess predictions derived from both positive and negative reinforcement models of drug use, the authors measured the acute effects of nicotine, as administered via tobacco cigarettes, on both positive and negative affect in a group of 15- to 18-year-old smokers. A matched group of nonsmokers served as a comparison group. Findings revealed that whereas adolescents who smoked a cigarette experienced reductions in both positive and negative affect, the observed reductions in negative affect were moderated by nicotine content of the cigarette (high yield vs. denicotinized), level of nicotine dependence, level of baseline craving, and smoking expectancies pertinent to negative affect regulation. Nonsmokers experienced no change in affect over the 10-min assessment period, and no interaction effects were observed for positive affect. Overall, the findings conform to a negative reinforcement model of nicotine effects and strongly suggest that, even among young light smokers, nicotine dependence and resultant withdrawal symptomatology may serve as motivating factors governing smoking behavior.     

Oral contraceptive use and hemodynamic, lipid, and fibrinogen responses to smoking and stress in women.

The effects of acute smoking and oral contraceptive (OC) use on cardiovascular, lipid, and fibrinogen stress responses were examined in 52 female smokers and nonsmokers, half of whom were using OCs. Women smoked or sham-smoked a cigarette and then performed 2 stressful tasks. Stress elicited increases in total and low-density lipoprotein cholesterol, and in triglycerides among women who smoked, and in fibrinogen among all women. Smokers who used OCs had greater blood pressure increases to smoking and to stress than did smokers who did not use OCs. OC use was also associated with enhanced total peripheral resistance stress responses among women who smoked and cardiac output stress responses among women who sham-smoked. Results suggest that OC use moderates cardiovascular reactivity in smokers but not nonsmokers, enhancing vascular responsivity to smoking combined with stress and myocardial responsivity to stress alone.     

Smoking,personality, and imagery preference in Relation to spontaneous bilateral electrodermal activity

Effects of smoking on spontaneous bilateral skin conductance were studied as a consequence of interactions with set and setting. Bilateral skin conductance was recorded in six men and six women who smoked and an equal number of nonsmokers on two different days. On the first day, spontaneous electrodermal activity was recorded before and after a 10-minute rest period during which half the smokers smoked a cigarette. On the second day, one week later, spontaneous activity was again recorded before and after a 10-minute rest period during which the remaining smokers smoked a cigarette. Nonsmokers did not smoke at any time. Following smoking there was a significant negative correlation between a preference for visual over nonvisual imagery and spontaneous skin conductance responsivity in the left as compared to the right hand. Correlations were significantly different in smokers and nonsmokers. Smokers showed significantly greater preferences for either visual or nonvisual imagery than nonsmokers. Nonresponding nonsmokers were higher on the psychoticism (P) scale of the Eysenck Personality Questionnaire (EPQ) than responding nonsmokers. Smokers scored higher on P than nonsmokers. Interactions between personality, cognitive style, and the experimental situation, set, and setting were discussed in relation to the arousing effects of nicotine.     

Associations Among Smoking,Anhedonia, and Reward Learning in Depression

Depression and cigarette smoking co-occur at high rates. However, the etiological mechanisms that contribute to this relationship remain unclear. Anhedonia and associated impairments in reward learning are key features of depression, which also have been linked to the onset and maintenance of cigarette smoking. However, few studies have investigated differences in anhedonia and reward learning among depressed smokers and depressed nonsmokers. The goal of this study was to examine putative differences in anhedonia and reward learning in depressed smokers (n = 36) and depressed nonsmokers (n = 44). To this end, participants completed self-report measures of anhedonia and behavioral activation (BAS reward responsiveness scores) and as well as a probabilistic reward task rooted in signal detection theory, which measures reward learning (Pizzagalli, Jahn, & O'Shea, 2005). When considering self-report measures, depressed smokers reported higher trait anhedonia and reduced BAS reward responsiveness scores compared to depressed nonsmokers. In contrast to self-report measures, nicotine-satiated depressed smokers demonstrated greater acquisition of reward-based learning compared to depressed nonsmokers as indexed by the probabilistic reward task. Findings may point to a potential mechanism underlying the frequent co-occurrence of smoking and depression. These results highlight the importance of continued investigation of the role of anhedonia and reward system functioning in the co-occurrence of depression and nicotine abuse. Results also may support the use of treatments targeting reward learning (e.g., behavioral activation) to enhance smoking cessation among individuals with depression.     

Gustatory responses during periods of controlled and ad lib cigarette smoking

Three psychophysical methods, differential sensitivity, perceived intensity, and degree of liking, were used to measure gustatory responses among nonsmokers and among smokers who were placed on 2-week schedules of increased and decreased cigarette consumption. Varying the smoking levels had little influence on the smokers’ sensitivity to the tastes of sucrose and sodium chloride. Throughout the experiments, nonsmokers were slightly more sensitive than smokers. Lower intensity ratings were ascribed to both compounds by smokers than by nonsmokers. Degree of liking of the test solutions was unrelated to smoking. A subsequent experiment showed that 45 nonsmokers were slightly, but not significantly, more sensitive than were 45 smokers to the tastes of sucrose, sodium chloride, citric acid, and quinine hydrochloride, with no differences in their sensitivity to the odor of 2-butanone and to the viscosity imparted by carrageenan gum. There was a slight inverse relationship between sensitivity and the number of cigarettes smoked per day. Smokers liked coffee significantly better and drank more cups per day than did nonsmokers. Few changes in body weight were observed, despite the smokers’ subjective assessment that their appetites and food intake were inversely related to the number of cigarettes smoked.     

Attentional bias affects change detection

Thirty smokers and 30 nonsmokers participated in aflicker study in which the role of attentional bias in change detection was examined. The participants observed picture pairs of everyday objects flicker on a computer screen until they detected the one object that had changed. In half of the pictures, a smoking-related object (e.g., a lighter) was included among smoking-unrelated objects (e.g., a spoon). Half of the smokers and half of the nonsmokers were aware of the experiment’s focus, and the other half were not. The smokers exhibited shorter detection latencies than did the nonsmokers when a smoking object changed and longer detection latencies when a nonsmoking object changed while a smoking object was present, and they exhibited detection latencies similar to those of the nonsmokers when smoking objects were not present. Interestingly, the nonsmokers displayed the same attentional bias as the smokers when they were aware of the experiment’s smoking focus, but they did not display any attentional bias when they were unaware. Thus, these findings provide evidence for long-term context-independent, as well as for short-term context-dependent, attentional bias.     

Effects of cigarette smoking on lexical decision-making

10 habitual smokers, aged 19-25 yr., were randomly assigned to smoke either a very low nicotine "Placebo" cigarette (.05-mg nicotine delivery as estimated by the FTC method) or a Nicotine cigarette (.7-mg estimated nicotine delivery). Each participant was asked to abstain from smoking for 4 to 7 hr. prior to testing. After completing a presmoking test of lexical decision-making, participants smoked either a Nicotine or Placebo cigarette and were then retested for reaction times and accuracy on the lexical decision test. When presented the most difficult lexical decisions, participants responded significantly faster after smoking a Nicotine cigarette than they did before smoking; smoking a Placebo cigarette did not affect reaction times. Response accuracy was unaffected by smoking either kind of cigarette. These results suggest that smoking a nicotine cigarette may improve attention or memory retrieval after several hours of smoking abstinence.     

Weak ventral striatal responses to monetary outcomes predict an unwillingness to resist cigarette smoking

As a group, cigarette smokers exhibit blunted subjective, behavioral, and neurobiological responses to nondrug incentives and rewards, relative to nonsmokers. Findings from recent studies suggest, however, that there are large individual differences in the devaluation of nondrug rewards among smokers. Moreover, this variability appears to have significant clinical implications, since reduced sensitivity to nondrug rewards is associated with poorer smoking cessation outcomes. Currently, little is known about the neurobiological mechanisms that underlie these individual differences in the responsiveness to nondrug rewards. Here, we tested the hypothesis that individual variability in reward devaluation among smokers is linked to the functioning of the striatum. Specifically, functional magnetic resonance imaging was used to examine variability in the neural response to monetary outcomes in nicotine-deprived smokers anticipating an opportunity to smoke—circumstances found to heighten the devaluation of nondrug rewards by smokers in prior work. We also investigated whether individual differences in reward-related brain activity in those expecting to have access to cigarettes were associated with the degree to which the same individuals subsequently were willing to resist smoking in order to earn additional money. Our key finding was that deprived smokers who exhibited the weakest response to rewards (i.e., monetary gains) in the ventral striatum were least willing to refrain from smoking for monetary reinforcement. These results provide evidence that outcome-related signals in the ventral striatum serve as a marker for clinically meaningful individual differences in reward-motivated behavior among nicotine-deprived smokers.     

Warning! The following packet contains shocking images: The impact of mortality salience on the effectiveness of graphic cigarette warning labels

This research looks at a recent initiative to encourage smokers to quit smoking and to discourage nonsmokers from starting to smoke. Evidence has shown that text‐based warning labels are ineffective in drawing attention to the dangers of tobacco consumption; therefore, some governments are looking to draw current smokers and potential smokers away from cigarettes by displaying graphic images of various smoking ailments. This research draws on Terror Management Theory as a means of understanding the effects of graphic visual images in cigarette packaging and offers implications for public health researchers, social marketers, and antismoking campaigners to help smokers to quit and reduce the likelihood of potential smokers becoming smokers. Copyright © 2012 John Wiley & Sons, Ltd.     

Five‐Year Prospective Study of Risk Factors for Daily Smoking in Adolescence Among Early Nonsmokers and Experimenters1

Grade 7 nonsmokers and experimenters (N= 4,165) were compared on a wide range of risk factors for future smoking derived from four prominent theories and whether these factors predicted daily smoking at Grade 12. Early experimenters scored consistently higher than did early nonsmokers on risk factors for future smoking. Common predictors of Grade 12 daily smoking for both groups included early exposure to an important adult who smokes, being young for one's cohort, and weak academic bonds. For Grade 7 non‐smokers, unique predictors of daily smoking included exposure to pro‐smoking social influences (cigarette offers, sibling who smokes), early binge drinking, and being female. Unique predictors for early experimenters were less sharply delineated, although certain family factors appeared to be more important for this group. African Americans and His‐panics were also less likely to progress from experimental to daily smoking. Results point to the importance of adapting prevention efforts to the special needs of early nonsmokers and experimenters.