Constructional Variety in the Spoken Language of School Children

Summary

Uncertainty scores (H and relative H) were computed for the verbs, noun phrases, and sentences produced by 180 children between the ages of 5 and 13 years on a story-telling task. Linear age trends occurred for Sentence H and relative H and for Noun-phrase H (though not relative H), but not for verb H and relative H. There were no overall sex differences, but measure-specific age-by-sex interactions and higher-order age trends. Uncertainty scores of the type proposed, if suitably refined, may measure the developmental progression from stereotyped reliance on individual syntactic forms to flexible utilization of productive rules.     

The influence of ADHD-hyperactivity/impulsivity symptoms on the development of oppositional defiant disorder symptoms in a 2-year longitudinal study

The structural relations among ADHD–inattention (IN), ADHD–hyperactivity/impulsivity (H/I), and oppositional defiant disorder (ODD) factors were examined in a 2-year longitudinal study with 752 children. Structural equation procedures showed that higher scores on the H/I factor in Year 1 were associated with higher scores on ODD factor in Years 2 and 3. Higher scores on the H/I factor in Year 2 were also associated with higher scores on ODD factor in Year 3. The ODD factor did not predict the H/I and IN factors in subsequent years. The IN factor did not predict the ODD and H/I factors in subsequent years and the H/I factor did not predict the IN factor. The ability of the H/I factor to predict the subsequent ODD factor occurred even after taking into account the ability of the ODD, H/I, and IN factors to predict themselves across time. These results suggest that the H/I aspect of ADHD influences the development of ODD behavior.     

A problem for the alternative difference measure of confirmation

Among Bayesian confirmation theorists, several quantitative measures of the degree to which an evidential proposition E confirms a hypothesis H have been proposed. According to one popular recent measure, s, the degree to which E confirms H is a function of the equation P(H|E) ? P(H|~E). A consequence of s is that when we have two evidential propositions, E1 and E2, such that P(H|E1) = P(H|E2), and P(H|~E1) ≠ P(H|~E2), the confirmation afforded to H by E1 does not equal the confirmation afforded to H by E2. I present several examples that demonstrate the unacceptability of this result, and conclude that we should reject s (and other measures that share this feature) as a measure of confirmation.     

幽门螺杆菌感染治疗新进展

在中国幽门螺杆菌(Helicobacter pylori,Hp)有非常高的感染率,国人感染率约55%,所以Hp感染处理中的临床问题是目前Hp研究领域中的重点课题,Hp感染治疗中的重要问题主要包括以下几方面:(1)哪些病人应该治疗?(治疗适应证问题);(2)如何治疗?(治疗方案问题);(3)如何避免或克服Hp对抗生素的耐药性问题?Hp对抗生素的耐药是Hp根除失败的主要原因,所以本文还要重点讨论Hp对抗生素的耐药牲,Hp根除失败的补救治疗及其治疗研究进展。     

Predicting psychological responses to influenza A, H1N1 ("swine flu"): the role of illness perceptions

Previous research on H1N1 ("Swine flu") has demonstrated that although the public reported concern about H1N1, knowledge levels were low, as were reports of behavioural changes aimed at minimising the spread of H1N1. The current study had two main aims; (i) to ascertain levels of state anxiety and knowledge about H1N1, and (ii) to examine if illness perceptions predict anxiety about H1N1, perceived risk of contracting H1N1, and knowledge about H1N1. The study was cross-sectional in design, and involved 235 participants (100 males, 135 females, mean age 22.48 years) completing self-report measures of knowledge, anxiety, and perceived risk about H1N1, and illness perceptions (BIPQ). Analyses revealed low levels of knowledge about H1N1, 37.4% of participants could not identify any of the causes of H1N1. Correlation and multiple regression analyses demonstrated that illness perceptions were associated with responses to H1N1, with negative illness perceptions predicting state anxiety (β?=?0.498, p?相似文献   

Gender differences in combined homicide‐suicide with consideration of female terrorist bombers

Combined homicide‐suicide (H‐S) is a phenomenon described as an offender committing a homicidal act followed by their suicide. Current literature on H‐S is dominated by a focus on men and their particular set of motivations and actions, primarily because females constitute only a small fraction of the cases of completed H‐S. This review begins by analyzing this data and integrating females within two subclassifications of H‐S: the psychopathology of the actor (or perpetrator), and the actor's relationship to her homicide victims. Within the relational subcategory of H‐S, females are: (1) underrepresented when victims are their spouses or intimate partners (consortial H‐S); (2) more prevalent when victims are their own children (filial H‐S); and (3) with rare exceptions, not represented in extrafamilial, adversarial and pseudo‐commando H‐S perpetrators. This review includes female bombers in this gender comparison.     

The effect of hypothermia on the rat's spatial memory in the water tank task

The effect of hypothermia on the retention of the water tank navigation task has been examined in 21 male hooded rats. After a 3-min swimming test on Day 1 the animals were trained on Days 2 and 3 (2 X 12 trials) to find a small submerged platform 1 cm below the surface of a large pool (120 cm in diameter) of opaque water. On Day 4, the rats were divided into three groups (n = 7) which were cooled to colonic temperatures of 22-24 degrees C (H1), 25-27 degrees C (H2), and 28-31 degrees C (H3), respectively, and given 12 retrieval trials in the water tank. Average escape latencies increased from 6 s in normothermic rats on Day 3 to 33, 19, and 12 s on Day 4 in the H1, H2, and H3 groups, respectively. Under the same testing conditions the performance of groups H1, H2, and H3 improved on Day 5 to 20, 8 and 6 s, respectively. It is concluded that spatial memory retrieval is resistant to mild hypothermia (30 degrees C), but that it is severely impaired at body temperatures below 25 degrees C. Reacquisition of the task is slowed down but not fully prevented in deep hypothermia.     

Dissociating explicit and implicit measures of sensed hand position in tool use: Effect of relative frequency of judging different objects

In a cursor-control task, the sensed positions of cursor and hand are biased toward each other. We previously found different characteristics of implicit and explicit measures of the bias of sensed hand position toward the position of the cursor, suggesting the existence of distinct neural representations. Here we further explored differences between the two types of measure by varying the proportions of trials with explicit hand-position (H) and cursor-position (C) judgments (C20:H80, C50:H50, and C80:H20). In each trial, participants made a reaching movement to a remembered target, with the visual feedback being rotated randomly, and subsequently they judged the hand or the cursor position. Both the explicitly and implicitly measured biases of sensed hand position were stronger with a low proportion (C80:H20) than with a high proportion (C20:H80) of hand-position judgments, suggesting that both measures place more weight on the sensory modality relevant for the more frequent judgment. With balanced proportions of such judgments (C50:H50), the explicitly assessed biases were similar to those observed with a high proportion of cursor-position judgments (C80:H20), whereas the implicitly assessed biases were similar to those observed with a high proportion of hand-position judgments (C20:H80). Because strong weights of cursor-position or hand-position information may be difficult to increase further but are easy to reduce, the findings suggest that the implicit measure of the bias of sensed hand position places a relatively stronger weight on proprioceptive hand-position information, which is increased no further by a high proportion of hand-position judgments. Conversely, the explicit measure places a relatively stronger weight on visual cursor-position information.     

Effect of MAO A deficiency on different kinds of aggression and social investigation in mice

Monoamine oxidase A (MAO A) degrades serotonin, dopamine and noradrenaline, factors critically involved in the regulation of aggression. Different kinds of aggression were investigated in Tg8, a transgenic mouse strain lacking a functional MAO A gene. MAO A-deficient mice differ from wild-type C3H/HeJ (C3H) in terms of showing higher territorial, predatory and isolation-induced aggression. Tg8 demonstrated shorter latencies to cricket killing and to the first attack after 6 weeks isolation than C3H mice. In the resident-intruder paradigm, MAO A-lacking mice were more aggressive than C3H when tested as intruders. In contrast to C3H, attack in Tg8 mice did not depend on different aggressiveness of intruders of BALB/c, A/Sn and C3H strains. Tg8 mice displayed no increase in aggression but demonstrated reduced social investigation towards anesthetized, as well as towards juvenile BALB/c males. Thus, MAO A deficiency in Tg8 mice is accompanied by increased expression of different kinds of aggression, as well as by disruption of normal pattern of social interaction.     

Characteristics of Family Interaction of Individuals with Hikikomori (Prolonged Social Withdrawal) From the Viewpoint of Behavior Theory

The cognitive behavioral approach for families of individuals with hikikomori (IWH) places importance on assessing family interaction from a behavior theory. However, there is no gold standard method for the assessment of family interaction of IWH. Additionally, the characteristics of the family interactions of IWH have not been clarified. This study aims to (a) develop the Family Interaction Scale for Hikikomori (FIS‐H) using parent‐reported data, and (b) clarify the characteristics of hikikomori cases. First, the FIS‐H factor structure was examined. Second, to examine the reliability and validity of the FIS‐H and the characteristics of hikikomori cases, parents of IWH (hikikomori‐group) and unaffected parents (without‐group) completed the FIS‐H and the Relationship Happiness Scale. Based on data from 146 parents, the FIS‐H preliminary version consisted of four factors with a total of 12 items (Study 1). The reliability and validity of the FIS‐H were also confirmed to be acceptable using data from 246 hikikomori‐group participants. The hikikomori‐group had higher FIS‐H scores than did the without‐group (Study 2). These results show that it is important to appropriately assess family interactions.     

Relational Uncertainty and Message Production Within Courtship: Features of Date Request Messages

This paper theorizes about how relational uncertainty may predict features of date request messages within courtship. It reports a study in which 248 individuals role‐played leaving a date request voice mail message for their partner. Relational uncertainty was negatively associated with the fluency (H1), affiliativeness (H2), relationship focus (H3), explicitness (H4), and perceived effectiveness (H5) of messages. Also as expected, relational uncertainty was negatively associated with people’s perceptions of the effectiveness of their messages after covarying the judgments of independent observers (H6). Relational uncertainty continued to predict features of messages when length of romantic interest was covaried (RQ1). The paper concludes by discussing the implications of the results for understanding the link between relational uncertainty and message production.     

Close to me: The importance of closeness versus superficiality in explaining the positive-negative contact asymmetry

The evidence for differential effects of positive and negative intergroup contact on prejudice is mixed. We propose that the closeness of the relationships respondents have with contact partners can explain inconsistencies in previous findings. In three studies (total N = 953), we tested the associations between positive intimate, negative intimate, positive superficial, and negative superficial contact and attitudes toward different outgroups (immigrants and gay people). We hypothesized that: (H1) the effect of positive contact would be maximized in intimate interactions; (H2) the effect of negative contact would be maximized in superficial interactions; (H3) positive intimate and negative superficial contact would have similar power in predicting attitudes. Results always supported H1, and supported H2 and H3 only with immigrants. Findings held also when controlling for category salience and agreeableness, but not for social dominance orientation, which instead strengthened the effect of negative superficial contact. Overall, findings clarify the positive–negative contact asymmetry.     

甲型H1N1流感普通型与重症型的处理

本文回顾性总结历史上几次世界性甲型流感流行和2009年H1N1流感流行情况。概述了2009年H1N1流感普通型病例的临床处理。重点阐述2009年H1N1流感重症型病例的高危人群、发生的危险因素以及临床表现。特别强调重症型流感抗病毒治疗的重要性及适应证。同时提醒关注神经氨酸酶抑制剂应用的耐药问题。     

The Development of Modern Logic

G. FREGE, Collected papers on mathematics, logic, and philosophy. Edited by B. McGuinness. Translated by M. Black, V. H. Dudman, P. Geach, H. Kaal, E.-H. W. Kluge, B. McGuinness and R. H. Stoothoff. Oxford and New York: Blackwell, 1984. viii + 412pp. £28.50.     

The effects of circumferential air-splint pressure on flexor carpi radialis H-reflex in subjects without neurological deficits

The purposes of this study were to investigate the effects of circumferential pressure on flexor carpi radialis (FCR) H-reflex in subjects without neuromuscular deficits and to evaluate the skin's contribution to this effect. FCR H-reflex was assessed in 43 subjects by measuring the peak-to-peak amplitude change before, during, and after circumferential pressure was applied to the forearm. Twelve H-reflexes (H/M ratio: M = 25%, SD = 14) were recorded before pressure application to obtain a baseline value (H(baseline)) to which all data were compared. A pneumatic 15 to 20-cm air splint inflated to 51-60 mmHg provided the pressure around the forearm. H-reflex recordings were taken at 1, 3, and 5 min. during (H(pressure)) and after pressure application. A second smaller study (placebo), in which the air splint was inflated to 0 mmHg, was conducted in 5 subjects to ensure that changes in reflex amplitudes were not a result of cutaneous effects. Two types of responses were observed in the FCR H-reflex following pressure application. One group of subjects significantly increased in H-reflex amplitude while another group decreased in H-reflex amplitude when compared to H(baseline). Regression analysis found that H(max) explained 37.2% of the variance when controlling for H(baseline). Subjects with larger H(max) showed an increase in H(pressure) while subjects with lower H(max) showed decreases in H(pressure) The placebo study revealed no differences in H-reflex amplitude from baseline values, implying that skin stimulation from the air splint has no role in the effects observed. The dichotomous result indicates that pressure influences the upper extremity differently than it does the lower extremity in certain individuals. Clinicians, using circumferential pressure as a therapeutic modality to lower muscle activity of the upper extremity, need to be cognizant that pressure may have contrasting effects on their patients.     

New polytypes of long-period stacking ordered structures in a near-equilibrium Mg97Zn1Y2 alloy

By atomic-scale high-angle annular dark-field scanning transmission electron microscopy, the long-period stacking ordered (LPSO) structures in a near-equilibrium Mg₉₇Zn₁Y₂ (at.%) alloy have been characterised. In addition to 18R and 14H, new polytypes of LPSO structures are analysed and determined as 60R, 78R, 26H, 96R, 38H, 40H, 108H and 246R. All of these LPSO structures feature AB′C′A building blocks with two Mg layers and three Mg layers sandwiched between them. The Bravais lattices and space groups of new polytypes of LPSO structures were easily determined via the newly introduced method. A structural relationship between the LPSOs is proposed.     

Rediscovering H. H. Farmer

Books reviewed in this article:
H. H. Farmer, C. H. Partridge (ed.), Reconciliation and Religion: Some Aspects of the Uniqueness of Christianity as a Reconciling Faith
C. H. Partridge, H. H. Farmer's Theological Interpretation of Religion: Towards a Personalist Theology of Religions     

Rescue of synaptic plasticity and spatial learning deficits in the hippocampus of Homer1 knockout mice by recombinant Adeno-associated viral gene delivery of Homer1c

Homer1 belongs to a family of scaffolding proteins that interact with various post-synaptic density proteins including group I metabotropic glutamate receptors (mGluR1/5). Previous research in our laboratory implicates the Homer1c isoform in spatial learning. Homer1 knockout mice (H1-KO) display cognitive impairments, but their synaptic plasticity properties have not been described. Here, we investigated the role of Homer1 in long-term potentiation (LTP) in the hippocampal CA1 region of H1-KO mice in vitro. We found that late-phase LTP elicited by high frequency stimulation (HFS) was impaired, and that the induction and maintenance of theta burst stimulation (TBS) LTP were reduced in H1-KO. To test the hypothesis that Homer1c was sufficient to rescue these LTP deficits, we delivered Homer1c to the hippocampus of H1-KO using recombinant adeno-associated virus (rAAV). We found that rAAV-Homer1c rescued HFS and TBS-LTP in H1-KO animals. Next, we tested whether the LTP rescue by Homer1c was occurring via mGluR1/5. A selective mGluR5 antagonist, but not an mGluR1 antagonist, blocked the Homer1c-induced recovery of late-LTP, suggesting that Homer1c mediates functional effects on plasticity via mGluR5. To investigate the role of Homer1c in spatial learning, we injected rAAV-Homer1c to the hippocampus of H1-KO. We found that rAAV-Homer1c significantly improved H1-KO performance in the Radial Arm Water Maze. These results point to a significant role for Homer1c in synaptic plasticity and learning.     

The observing subject and psychophysiological research: An epistemological discourse

Realizing that scientific knowledge was not based on a simple disclosure of reality, but was rather invented and developed in accordance with our own conceptions and prejudices, it should no longer be possible to consider matters as if they existed independently of us out there.Taking as examples the notions of memory and information we try to elucidate the relevance this perspective has with respect to neuro- and psychophysiological research.     

幽门螺杆菌与胃癌关系的研究进展

幽门螺杆菌(H.pylori,Hp)是胃癌的发病因素之一,二者之间的关系非常密切。Hp感染蒙古沙土鼠成功诱发胃癌,在动物实验中直接证实Hp与胃癌发生有关。众多大规模的人群干预研究显示Hp感染可增加胃癌发病率,根除Hp后胃癌的发生有减少趋势;Hp毒力基因尤其是cag致病岛与胃癌发生关系密切。宿主反应基因尤其是前炎症细胞因子与胃癌的危险性增高有关。动物模型显示Hp诱导癌前病变的发生与上皮细胞周期的调控失常、细胞增殖与调亡的失衡相关。