Attention and recognition biases associated with stature dissatisfaction among young men in China

This research evaluated information-processing biases related to height dissatisfaction among young Chinese men. In Study 1, 32 highly stature dissatisfied (HSD) men and 36 less stature dissatisfied (LSD) men performed a dot probe task featuring height-related words and neutral words. HSD men were significantly slower than LSD men were in responding to probes that followed short stature words, but the groups did not differ in response speeds to probes that followed tall stature or neutral words. In Study 2, 33 HSD men and 34 LSD men completed an implicit learning task followed by a word recognition task. HSD men recognized significantly more short stature words from the initial task, but recognition accuracy for other word types did not differ between groups. Together, these findings suggest that HSD men are more inclined than LSD men to selectively avoid cues that reflect shortness in stature and to selectively recognize such cues later.     

Combined behavioural markers of cognitive biases are associated with anhedonia

Biases towards negative information, as well as away from positive information, are associated with psychopathology. Examining biases in multiple processes has been theorised to be more predictive than examining bias in any process alone. Anhedonia is a core symptom of psychopathology and predictive of future psychopathological symptoms. Finding that combined biases are associated with anhedonia would advance knowledge of the nature of emotional processing biases and the value of objective performance-based measures for identifying early risk markers. Participants (N?=?139) completed tasks that assess latency bias (dot probe) and biased recognition (two-alternative forced-choice) of emotional information, as well as an anhedonia measure. An index was computed for each task’s performance reflecting biased processing of positive and negative words. Only combined biases on both tasks were associated with anhedonia. Attentional bias was positively associated with anhedonia, but only when recognition bias for emotional words was high. Thus, assessing biases in multiple domains increased sensitivity to uncover relationships between emotional processing biases and anhedonic symptoms.     

Children's 5-HTTLPR genotype moderates the link between maternal criticism and attentional biases specifically for facial displays of anger

Theorists have proposed that negative experiences in childhood may contribute to the development of experience-specific information-processing biases, including attentional biases. There are also clear genetic influences on cognitive processes, with evidence that polymorphisms in specific candidate genes may moderate the impact of environmental stress on attentional biases (e.g., a functional polymorphism in the serotonin transporter gene; 5-HTTLPR). In the current study, we tested a gene×environment (G×E) model of risk for attentional biases. We hypothesised that children whose mothers exhibit high levels of expressed emotion criticism (EE-Crit) would display attentional biases specifically for angry, but not happy or sad, faces, and that this link would be stronger among children carrying one or two copies of the 5-HTTLPR short allele than among those homozygous for the long allele. Results generally supported these hypotheses, though we found that carriers of the 5-HTTLPR short allele who also had a critical mother exhibited attentional avoidance of angry faces rather than preferential attention.     

Dyslexia and handedness: developmental phonological and surface dyslexias are associated with different biases for handedness

Developmental disorders of reading and spelling have long been associated with increased left- and mixed-handedness but the evidence has been controversial. The right shift (RS) theory of handedness and cerebral dominance, developed by Annett from 1972 onward, offers resolutions to several puzzles about laterality in the so-called dyslexias. This review of findings in the light of the theory shows that "phonological" dyslexics are less likely to be right-handed, while "surface" or "dyseidetic" dyslexics are more likely to be right-handed than the general population.     

Attention and joint attention in preschool children with autism

Three experiments examined the role of attention in explaining dyadic (child-adult) and triadic (child-adult-object) joint attention difficulties in autism. Experiments 1 and 2 investigated children's ability to orient to an adult's attention bid and to follow the direction of a human or nonhuman cue. Experiment 3 tested ability to disengage and shift attention to objects. Results showed autism-specific difficulties at both dyadic and triadic levels. Children with autism were less responsive than developmentally delayed controls in orienting to attention bids and in following a human head-turn cue yet had no difficulty in shifting attention and were faster overall in orienting to targets. Results suggest a specific developmental delay in which children with autism rely on the presence of objects in the visual field to guide action. The relation between this problem and autistic children's difficulties with human communicative signals is discussed.     

Extraversion, attention, and habituation of the auditory evoked response

Short-term changes in the auditory evoked response to low-frequency tones (0.5 kHz, 80 dB) were examined for independent groups of introverts and extraverts under attend and ignore conditions. Introverts displayed greater N1-P2 amplitude than extraverts to the first stimulus in a four-stimulus train. The N1-P2 amplitude differences between introverts and extraverts could not be attributed to differences between the groups in either habituation or attention processes. Overall, the effect is indicative of the introverts' enhanced sensitivity to physical stimulation.     

Attention and memory biases for aggressive information in college students with fragile high self-esteem

In this study, we examined attention and memory biases for aggressive information in two groups of college students. Individuals with fragile high self-esteem (n = 30) and individuals with secure high self-esteem (n = 30) first performed a dot-probe task investigating attention bias, followed by a memory task. Incidental free recall of words presented in the memory task was then completed to assess memory bias. Results revealed that individuals with fragile high self-esteem exhibited significant attention and memory biases for aggressive words compared with secure high self-esteem individuals. Attention bias for aggressive words was positively correlated with memory bias in individuals with fragile high self-esteem, but no correlation was found for individuals with secure high self-esteem. These findings suggest that individuals with fragile high self-esteem selectively attend to and remember aggression-related information. They may process information in ways that are congruent with an aggression-related schema. This study reveals the aggressive cognitive processes of individuals with fragile high self-esteem, which may be related to aggression.     

Serotonin transporter 5-HTTLPR genotype is associated with intrusion and avoidance symptoms of DSM-5 posttraumatic stress disorder (PTSD) in Chinese earthquake survivors

Background and Objectives: Prior studies have found that the serotonin transporter gene-linked polymorphic region (5-HTTLPR) interacts with trauma exposure to increase general risk for Posttraumatic Stress Disorder (PTSD). However, there is little knowledge about the effects of the interaction on distinct symptom clusters of PTSD. This study aimed to investigate the relation between the interaction of 5-HTTLPR and earthquake-related exposures and a contemporary phenotypic model of DSM-5 PTSD symptoms in a traumatised adult sample from China.

Design: A cross-sectional design with gene-environment interaction (G?×?E) approach was adopted. Methods: Participants were 1131 survivors who experienced 2008 Wenchuan earthquake. PTSD symptoms were assessed with the PTSD Checklist for DSM-5 (PCL-5). The 5-HTTLPR polymorphism was genotyped with capillary electrophoresis (CE) in ABI 3730xl genetic Analyzer.

Results: Although there was no significant interaction between 5-HTTLPR and traumatic exposure on total PTSD symptoms, respondents with the LL genotype of 5-HTTLPR who were highly exposed to the earthquake experienced lower intrusion and avoidance symptoms than those with the S-allele carriers.

Conclusions: The findings suggest that the 5-HTTLPR may have an important impact on the development of PTSD and add to the extant knowledge on understanding and treating of posttraumatic psychopathology.     

Exploring the perceptual biases associated with believing and disbelieving in paranormal phenomena

Ninety-five participants (32 believers, 30 disbelievers and 33 neutral believers in the paranormal) participated in an experiment comprising one visual and one auditory block of trials. Each block included one ESP, two degraded stimuli and one random trial. Each trial included 8 screens or epochs of “random” noise. Participants entered a guess if they perceived a stimulus or changed their mind about stimulus identity, rated guesses for confidence and made notes during each trial. Believers and disbelievers did not differ in the number of guesses made, or in their ability to detect degraded stimuli. Believers displayed a trend toward making faster guesses for some conditions and significantly higher confidence and more misidentifications concerning guesses than disbelievers. Guesses, misidentifications and faster response latencies were generally more likely in the visual than auditory conditions. ESP performance was no different from chance. ESP performance did not differ between belief groups or sensory modalities.     

Stressful life events, perceived stress, and 12-month course of geriatric depression: direct effects and moderation by the 5-HTTLPR and COMT Val158Met polymorphisms

Although the relation between stressful life events (SLEs) and risk of major depressive disorder is well established, important questions remain about the effects of stress on the course of geriatric depression. Our objectives were (1) to examine how baseline stress and change in stress is associated with course of geriatric depression and (2) to test whether polymorphisms of serotonin transporter (5-HTTLPR) and catechol-O-methyltransferase (COMT Val158Met) genes moderate this relation. Two-hundred and sixteen depressed subjects aged 60 years or older were categorized by remission status (Montgomery-Asberg depression rating scale≤6) at 6 and 12 months. At 6 months, greater baseline numbers of self-reported negative and total SLEs and greater baseline perceived stress severity were associated with lower odds of remission. At 12 months, only baseline perceived stress predicted remission. When we examined change in stress, 12-month decrease in negative SLEs and level of perceived stress were associated with improved odds of 12-month remission. When genotype data were included, COMT Val158Met genotype did not influence these relations. However, when compared with 5-HTTLPR L/L homozygotes, S allele carriers with greater baseline numbers of negative SLEs and with greater decrease in negative SLEs were more likely to remit at 12 months. This study demonstrates that baseline SLEs and perceived stress severity may influence the 12-month course of geriatric depression. Moreover, changes in these stress measures over time correlate with depression outcomes. 5-HTTLPR S carriers appear to be more susceptible to both the effects of enduring stress and the benefit of interval stress reduction.     

A review of cognitive biases in youth depression: attention,interpretation and memory

Depression is one of the most common mental health problems in childhood and adolescence. Although data consistently show it is associated with self-reported negative cognitive styles, less is known about the mechanisms underlying this relationship. Cognitive biases in attention, interpretation and memory represent plausible mechanisms and are known to characterise adult depression. We provide the first structured review of studies investigating the nature and causal role of cognitive biases in youth depression. Key questions are (i) do cognitive biases characterise youth depression? (ii) are cognitive biases a vulnerability factor for youth depression? and (iii) do cognitive biases play a causal role in youth depression? We find consistent evidence for positive associations between attention and interpretation biases and youth depression. Stronger biases in youth with an elevated risk of depression support cognitive-vulnerability models. Preliminary evidence from cognitive bias modification paradigms supports a causal role of attention and interpretation biases in youth depression but these paradigms require testing in clinical samples before they can be considered treatment tools. Studies of memory biases in youth samples have produced mixed findings and none have investigated the causal role of memory bias. We identify numerous areas for future research in this emerging field.     

Mixed signals: The effect of conflicting reward- and goal-driven biases on selective attention

Attentional selection depends on the interaction between exogenous (stimulus-driven), endogenous (goal-driven), and selection history (experience-driven) factors. While endogenous and exogenous biases have been widely investigated, less is known about their interplay with value-driven attention. The present study investigated the interaction between reward-history and goal-driven biases on perceptual sensitivity (d’) and response time (RT) in a modified cueing paradigm presenting two coloured cues, followed by sinusoidal gratings. Participants responded to the orientation of one of these gratings. In Experiment 1, one cue signalled reward availability but was otherwise task irrelevant. In Experiment 2, the same cue signalled reward, and indicated the target’s most likely location at the opposite side of the display. This design introduced a conflict between reward-driven biases attracting attention and goal-driven biases directing it away. Attentional effects were examined comparing trials in which cue and target appeared at the same versus opposite locations. Two interstimulus interval (ISI) levels were used to probe the time course of attentional effects. Experiment 1 showed performance benefits at the location of the reward-signalling cue and costs at the opposite for both ISIs, indicating value-driven capture. Experiment 2 showed performance benefits only for the long ISI when the target was at the opposite to the reward-associated cue. At the short ISI, only performance costs were observed. These results reveal the time course of these biases, indicating that reward-driven effects influence attention early but can be overcome later by goal-driven control. This suggests that reward-driven biases are integrated as attentional priorities, just as exogenous and endogenous factors.     

The effects of inattention on selective attention: How sadness and ruminations alter attention functions evaluated with the Attention Network Test

In two in-laboratory studies, we investigated the influence of inattention when caused by sadness and ruminations on attention functions. Being sad and ruminating over negative thoughts involves a long-lasting attentional self-focus, altering the ability to process relevant information from the environment. It subsequently leads to inattention, considered as a very specific attention deficit. In a preliminary methodological study, it was demonstrated that the combined imagery vignettes and music procedure was efficient to induce sadness and ruminations, propitious to inattention. Then, in a second experiment, sadness and ruminations were induced with this procedure in order to provoke inattention. The effects of inattention on selective attention processes were assessed using the Attention Network Test, which discriminates between three independent attention functions: alerting, orienting and conflict. Results on reaction times showed that only the orienting function was affected when inattentive, with a significant alteration on spatial information processing. These results were discussed in the light of the literature on emotion and attention.     

Attentional biases in dysphoria: An eye-tracking study of the allocation and disengagement of attention

This study looked for evidence of biases in the allocation and disengagement of attention in dysphoric individuals. Participants studied images for a recognition memory test while their eye fixations were tracked and recorded. Four image types were presented (depression-related, anxiety-related, positive, neutral) in each of two study conditions. For the simultaneous study condition, four images (one of each type) were presented simultaneously for 10 seconds, and the number of fixations and the total fixation time to each image was measured, similar to the procedure used by Eizenman et al. (2003) and Kellough, Beevers, Ellis, and Wells (2008). For the sequential study condition, four images (one of each type) were presented consecutively, each for 4 seconds; to measure disengagement of attention an endogenous cuing procedure was used (Posner, 1980). Dysphoric individuals spent significantly less time attending to positive images than non-dysphoric individuals, but there were no group differences in attention to depression-related images. There was also no evidence of a dysphoria-related bias in initial shifts of attention. With respect to the disengagement of attention, dysphoric individuals were slower to disengage their attention from depression-related images. The recognition memory data showed that dysphoric individuals had poorer memory for emotional images, but there was no evidence of a conventional mood-congruent memory bias. Differences in the attentional and memory biases observed in depressed and dysphoric individuals are discussed.     

The influence of attention upon anticipatory arousal,habituation, and reactivity to a noxious stimulus

Forty subjects were assigned to four groups, an External-attending Group, an Internal-attending Group, a Control Group, and a Distracted Group. All groups were presented with six trials of a 0.5-sec 110-db white noise. A measure of heart rate deceleration verified the experimental manipulation of attention. During the anticipatory period, the Internal-attending Group exhibited the greatest and the Distracted Group exhibited the least reactivity among the four groups. The two specially attending groups exhibited greater galvanic skin-response conditioning during the anticipatory period than the other groups. There was no support for the hypothesis that heightened attention facilitates habituation. Two measures were differentially sensitive to direction of attention during the anticipatory period. The External-attending Group exhibited reliably greater anticipatory deceleration of heart rate than the Internal-attending Group, while the Internal-attending Group exhibited reliably more nonspecific electrodermal responses than the External-attending Group. This latter finding, along with other evidence, suggests that an inward direction of attention tends to exacerbate anticipatory anxiety as well as reactivity to the impact of a noxious stimulus.     

Attention and memory protection: Interactions between retrospective attention cueing and interference

Visual working memory (VWM) and attention have a number of features in common, but despite extensive research it is still unclear how the two interact. Can focused attention improve VWM precision? Can it protect VWM from interference? Here we used a partial-report, continuous-response orientation memory task to examine how attention and interference affect different aspects of VWM and how they interact with one another. Both attention and interference were orthogonally manipulated during the retention interval. Attention was manipulated by presenting informative retro-cues, whereas interference was manipulated by introducing a secondary interfering task. Mixture-model analyses revealed that retro-cues, compared to uninformative cues, improved all aspects of performance: Attention increased recall precision and decreased guessing rate and swap-errors (reporting a wrong item in memory). Similarly, performing a secondary task impaired all aspects of the VWM task. In particular, an interaction between retro-cue and secondary task interference was found primarily for swap-errors. Together these results suggest that both the quantity and quality of VWM representations are sensitive to attention cueing and interference modulations, and they highlight the role of attention in protecting the feature–location associations needed to access the correct items in memory.     

5-HTTLPR基因多态性和早期养育压力对学前儿童问题行为的影响

本研究拟探讨5-HTTLPR基因多态性与母亲早期养育压力对中国汉族学前儿童问题行为的交互作用机制和性别差异。355名6个月婴儿及其父母参加了本研究。在婴儿6个月时，收集婴儿的口腔脱落细胞和母亲养育压力数据；在48个月时，再次邀请父母分别报告儿童的问题行为。结果发现：（1）当母亲养育压力较高时，s/s和s/l型男孩的外显问题行为显著高于l/l型男孩；但当母亲养育压力较低时，两组男孩没有显著差异；（2）当母亲养育压力较高时，l/l型女孩的内隐问题行为显著高于s/s和s/l型女孩；但当母亲养育压力较低时，两组女孩没有显著差异。研究结果表明，5-HTTLPR基因多态性与母亲养育压力在预测男孩外显问题行为和女孩内隐问题行为时的交互作用机制均支持素质-压力模型。     

Uncertainty is associated with increased selective attention and sustained stimulus processing

Uncertainty about future threat has been found to be associated with an overestimation of threat probability and is hypothesized to elicit additional allocation of attention. We used event-related potentials to examine uncertainty-related dynamics in attentional allocation, exploiting brain potentials’ high temporal resolution and sensitivity to attention. Thirty participants performed a picture-viewing task in which cues indicated the subsequent picture valence. A certain-neutral and a certain-aversive cue accurately predicted subsequent picture valence, whereas an uncertain cue did not. Participants overestimated the effective frequency of aversive pictures following the uncertain cue, both during and after the task, signifying expectancy and covariation biases, and they tended to express lower subjective valences for aversive pictures presented after the uncertain cue. Pictures elicited increased P2 and LPP amplitudes when their valence could not be predicted from the cue. For the LPP, this effect was more pronounced in response to neutral pictures. Uncertainty appears to enhance the engagement of early phasic and sustained attention for uncertainly cued targets. Thus, defensive motivation related to uncertainty about future threat elicits specific attentional dynamics implicating prioritization at various processing stages, especially for nonthreatening stimuli that tend to violate expectations.