Severity and cost of unsafe abortion complications treated in Nigerian hospitals

CONTEXT: Each year, thousands of Nigerian women have unintended pregnancies that end in illegal abortion. Many such procedures occur under unsafe conditions, contributing to maternal morbidity and mortality. METHODS: In a 2002-2003 survey of women and their providers in 33 hospitals in eight states across Nigeria, 2,093 patients were identified as being treated for complications of abortion or miscarriage or seeking an abortion. Women's abortion experiences and the health consequences and associated costs were examined through bivariate analysis. Multivariate analysis was used to examine the characteristics of women by type of pregnancy loss and to compare characteristics among three groups of women who had induced abortions in differing circumstances. RESULTS: Among women admitted for abortion-related reasons, 36% had attempted to end the pregnancy before coming to the hospital (including 24% with and 12% without serious complications), 33% obtained an induced abortion at the facility (not withstanding the country's restrictive law) without having made a prior abortion attempt and 32% were treated for complications from a miscarriage. Of women with serious complications, 24% had sepsis, 21% pelvic infection and 11% instrumental injury; 22% required blood transfusion and 10% needed abdominal surgery. The women in this group were poorer and later in gestation than those who sought abortions directly from hospitals. They paid more for treatment (about 13,900 naira) than those who went directly to the hospital for an abortion (3,800 naira) or those treated for miscarriage (5,100 naira). CONCLUSIONS: Policy and program interventions are needed to improve access to contraceptive services and postabortion care in order to reduce abortion-related morbidity and mortality.     

室间隔缺损合并重度肺动脉高压的外科手术治疗策略

探讨室间隔缺损伴重度肺动脉高压患者手术指征的判断标准和围术期的治疗策略。11例室间隔缺损伴重度肺动脉高压患者,在体外循环下行室间隔缺损修补术,围术期给予吸氧、前列腺素E1等降低肺动脉压力的综合治疗。结果11例手术患者全部治愈出院,经随访肺动脉压力有着不同程度的下降。术前全面检查、综合分析以明确手术指征是室间隔缺损合并重度肺动脉高压患者获得满意疗效的根本,其中肺血管纹理是一个最重要的判断指标。     

Reye-like syndrome following valproate therapy in an adult

Three months after anticonvulsive regulation by means of the spasmolytic agent Convulsofin, a 46-year-old man suffered severe hepatosis, and when the preparation was discontinued he suffered a severe cerebral dysfunction. The clinical picture is interpreted as being "similar to the Reye syndrome", and distinctions between this and previously reported cases are noted. There has been very little observation of such complications among adult patients.     

Impact of personality disorders on treatment outcome for female assault survivors with chronic posttraumatic stress disorder

This study examined the impact of comorbid personality disorders on the outcome of cognitive behavioral treatment for women with chronic posttraumatic stress disorder (PTSD). Seventy-five adult women with PTSD resulting from rape or nonsexual assault in adulthood or sexual abuse in childhood were treated with prolonged exposure with or without cognitive restructuring. Assessment of personality disorders found that 39% of participants met DSM-IV criteria for some personality disorder diagnosis. No difference was found between women with and without personality disorders on the prevalence of PTSD at the end of treatment. Participants with a personality disorder were less likely to attain good end-state functioning, but this may be attributable to the fact that they started off slightly worse than those without personality disorders. Finally, the comorbid patients treated by community therapists fared as well or better than those treated by cognitive behavioral treatment experts in posttreatment prevalence of PTSD and end-state functioning.     

原发灶切除在转移性乳腺癌治疗中的地位

无论是国内还是世界其他国家,乳腺癌近年来已成为女性常患恶性肿瘤之首。早期乳腺癌通过手术、化疗、放疗及内分泌治疗等综合治疗后可以达到长期生存。然而对于晚期乳腺癌,特别是伴有远处转移的乳腺癌,疗效却不尽如人意。对于转移性乳腺癌,目前治疗优先选择毒性尽可能小的全身系统性治疗方案;而对于需要缓解症状或避免即将发生并发症（如皮肤溃疡、出血、真菌感染以及疼痛等）的情况可于全身治疗后行相应手术。然而对于转移性乳腺癌是否手术切除原发灶以及是否可从手术中获益,仍然充满争议。     

The impact of borderline personality disorder on process group outcome among women with posttraumatic stress disorder related to childhood abuse.

The outcome of a 12-week interpersonal process group therapy for women with postraumatic Stress Disorder (PTSD) related to childhood sexual abuse with and without borderline personality disorder (BPD) was assessed by comparing three naturally occurring treatment conditions: groups that did not have any members with borderline personality disorder (BPD-) (n = 18), groups in which at least one member carried the diagnosis (BPD+)(n = 16), and a 12-week waitlist (WL) (n = 15). PTSD, anger, depression, and other symptoms were significantly reduced in the BPD- groups. However, the BPD+ and WL conditions did not show any pre- to posttreatment improvements. Furthermore, the BPD+ condition showed a significant worsening on measures of anger. Analyses within the BPD+ condition indicated that women with and without the diagnosis experienced equal posttreatment increases in anger problems. These latter results suggest the presence of an anger "contagion" effect. That is, women without BPD did well in the BPD- groups but showed increased anger similar to the BPD+ women when treated in groups with them. Implications for client-treatment matching considerations in PTSD group therapy are discussed.     

Interpersonal Style and Hypothetical Treatment Choice Among Survivors of Intimate Partner Violence

Individual differences between women victimized by intimate partner violence (IPV) may account for whether they choose to seek treatment and what kind of treatment they might prefer. Recent research has highlighted the importance of interpersonal warmth and dominance on women’s response to IPV, although this has not yet been extended to area of treatment choice in the aftermath of IPV victimization. In this study, we examined the association between interpersonal warmth and dominance on four choices of hypothetical treatment (individual therapy only, medication only, combined therapy and medication, and no treatment) in a sample of young adult women victimized by IPV (N = 117). Results indicated that the majority of women would choose therapy (with or without medication) and that interpersonal warmth was negatively associated, and dominance positively associated, with a preference for medication only. These findings extend previous research on both treatment choice and interpersonal style within the context of IPV.     

Treatment of secondary orgasmic dysfunction: a comparison of systematic desensitization and sex therapy

Forty-eight couples complaining of secondary orgasmic dysfunction were randomly allocated to one of three treatment methods or to a control group. Sexual function, sexual anxiety and satisfaction with the total relationship were evaluated in a pretest, an intermediate test (after 12 therapeutic sessions) and a follow-up test. The intermediate test revealed significant improvement in the sexual function of women treated by systematic desensitization, and that of women and men treated by an adapted version of the Masters and Johnson method. The follow-up test showed significant improvement in women and men treated by desensitization. Both methods significantly improved the satisfaction with the total relationship in men and women, and desensitization significantly reduced sexual anxiety in men and women. The results of combined treatment —desensitization followed by treatment according to Masters and Johnson—were very poor. The control group showed no significant changes. Evaluation of the differences between the treatments revealed a near-significant difference in sexual function of women in the intermediate test, with desensitization and the Masters and Johnson method yielding better results than combined treatment or no treatment.     

Psychosocial factors influencing American men and women in their decision for sterilization

A self-administered questionnaire was answered by nearly 300 surgically sterilized men and over 200 such women 6 weeks after their surgery. Nearly half of these Americans were from large families. More women than men reported a history of medical, gynecologic, or psychiatric problems; one half had been pregnant four or more times; one third reported recent pregnancy. Most sterilized people reported an unsatisfactory contraceptive history. Despite that women had more complications from the procedure than men, improved psychosocial adjustment between 6 weeks before and 6 weeks after sterilization was reported by more women than men.     

Women’s Understanding and Attitudes towards Down Syndrome and Other Genetic Conditions in the Context of Prenatal Screening

In order to explore the impact of potential new technologies in the area of prenatal screening, we conducted a baseline study using qualitative interviews to explore women’s attitudes and knowledge regarding current and future prenatal screening technology and methods. Three cohorts were interviewed, including healthy women without children, healthy women with healthy children, and healthy women with children who have de novo genetic disorders. This study aimed to assess the baseline understanding and attitudes of women in Western Australia. Women from each cohort demonstrated adequate knowledge of the differences between screening and diagnostic tests, but were mostly unaware of the conditions for which screening is currently available except Down syndrome. Women who had children with de novo genetic conditions were generally aware of more genetic conditions than women with or without healthy children. Most women recognised the genetic basis for the conditions mentioned. Two thirds of women understood that Down syndrome is a chromosomal condition; just one third recognised that the phenotype is variable. Most women expressed a positive attitude towards Down syndrome. Social acceptance of children with Down syndrome was commonly mentioned as a concern. While the majority of women with children supported screening for Down syndrome, they emphasised that it must be an autonomous choice. General knowledge of genetic conditions illustrated that women are exposed to diverse conditions from lived experience as well as the media.     

Anxiety and depression in women with advanced cancer: Implications for counselling

Fifty-three patients with advanced cancer were studied prospectively for 6 months to assess whether the site and method of chemotherapy administration influence levels of anxiety and depression. Patients received chemotherapy either at home or in hospital. Cases of clinical anxiety (36%) and depression (27%) were highest in the hospital treated group during the middle period of therapy. Patients treated at home had a lower psychiatric morbidity for anxiety (21%) and depression (21%) at the same period. There was no statistically significant difference in the mean scores on anxiety and depression between the groups. Overall, anxiety was more prevalent than depression. This study indicates that a minority of patients with advanced cancer treated by chemotherapy experience measureable psychiatric morbidity. Counselling services should be provided for these women throughout treatment, not just at the outset.     

Epilepsy by looking at patterns]

The author, after pointing out the rare occurence and peculiarities of pattern-sensitive forms of epilepsy, reports the case of a seven-year-old boy with infantile cerebral paresis characterized by symptomatic attacks, who was observed to show absence-like conditions when looking at small-checkered patterns of nylon fabric. Grasping and looking at such fabrics assumed the form of an addiction, with a sense of pleasure being believed to be derived therefrom. Although anticonvulsive therapy resulted in attacks of epilepsy being no longer detectable clinically and by electroencephalography, seizures were still triggered by looking at patterns. Also discussed in this article is the problem of transition from real to psychogenic attacks.     

Stationäre körperbezogene Psychotherapie bei Anorexia und Bulimia nervosa

Disturbances of body-images in women with anorexia and bulimia nervosa are described at the behavioral, perceptional and affective-cognitive level. The disturbances of body image, which are often accompanied by personality-structural deficits and have a decisive influence on the course of disease, can be reached only in part by verbal forms of therapy. Considering these facts, we present an integrative clinical procedure in which the application of body-related therapy modules play a central role in supplement to cognitive-behavioral and psychodynamic forms of therapy. Process-oriented body-perception therapy in an individual setting and a communicative movement group therapy are used and their relevance to the in-patient therapy process examined from the patient’s point of view. The study reveals a high value of body-psychotherapy, wherebydifferences were observed between anorexia (15) and bulimia (27) patients in the course of the process. The results suggest an indication for the application of combined individual and group body-psychotherapy for hospitalized anorexia patients. A communicative body therapy in group form is also very important in the in-patient treatment of bulimia patients, but there is a differential indication with regard to individual body therapy.     

Outpatient group psychotherapy following day treatment for patients with personality disorders

This prospective, naturalistic study evaluated the practice and effectiveness of an outpatient group therapy program following day treatment for patients with personality disorders (PDs). One hundred and eighty-seven patients (86% patients with PDs and 14% with no PDs), were treated in outpatient psychodynamic group therapy. Outcome was assessed by Global Assessment of Functioning, Symptom Check List 90-R, and Inventory of Interpersonal Problems-Circumplex, short version, at admission and discharge from day treatment, and at the end of outpatient group therapy. Average length of outpatient therapy was 24 months. Forty-three percent terminated in an irregular manner. Outcome of the continuation therapy was satisfactory for patients without PDs. For PD patients, the improvement from the day treatment was maintained during outpatient therapy, but further improvements were modest for symptoms and interpersonal distress, somewhat better for global functioning. Implications for further treatment development are discussed.     

Propionibacterium granulosum KP-45 in the treatment of subacute sclerosing panencephalitis

3 groups of patients, who suffered on SSPE (without treatment, with isoprinosine therapy, combined treatment with propionibacterium granulosum and isoprinosine) are compared. The results show a favourable effect of the combined treatment in a part of the patients. They are discussed in detail.     

Treatment of pharmacotherapy-refractory posttraumatic stress disorder among Cambodian refugees: a pilot study of combination treatment with cognitive-behavior therapy vs sertraline alone

Cambodian refugees with posttraumatic stress disorder (PTSD) represent a cohort in severe need of treatment, but little information is available to guide treatment choices. We selected a sample of pharmacotherapy-refractory individuals to test the efficacy of combination treatment with sertraline and cognitive-behavior therapy (CBT) for treating PTSD. Participants in this pilot study were ten Khmer-speaking women who had been at a mean age of 22-26 years during the Pol Pot period (1975-1979). These patients were randomly assigned to either sertraline alone or combined treatment. We found that combined treatment offered additional benefit in the range of medium to large effect sizes for PTSD and associated symptoms. Our findings indicate that substantial gains can be achieved by adding CBT to pharmacotherapy for PTSD, and that a program of CBT emphasizing information, exposure, and cognitive-restructuring can be successfully modified for Khmer-speaking refugees.     

Most Admired Women and Men: Gallup,Good Housekeeping,and gender

In order to understand how gender roles influence the selection of people who are admired, we analyzed the results of the Most Admired Men and Women polls conducted annually by Gallup and Good Housekeeping. Most Admired Men were more likely than women to have achieved their fame without sponsorship of a well-known family or spouse. However, the proportion of Autonomous women was higher in the 1980s and 1990s than previously. Men were more likely to be admired for their service in the military, politics, religion, and economics; women were more likely to be admired because they belonged to a royal or political family, or because of their work as activists and reformers or in the area of entertainment and culture. A small percentage of both men and women had been the victim of personal tragedy. The great majority of the admired individuals were White Americans. No Hispanics or Native Americans made the lists, and all but one of the Asians were women. In short, both gender and ethnic stereotypes seem to have influenced the choice of Most Admired Men and Women.     

Effectiveness of an empirically supported treatment for social phobia in the field

This study examined the effectiveness of individual exposure combined with cognitive restructuring for social phobia in a clinical setting as well as the influence of sample restriction criteria on the effect size. Participants were 217 unselected patients with a primary diagnosis of social phobia who were treated by 57 therapists in four outpatient clinics of the Christoph-Dornier-Foundation of Clinical Psychology in Germany. Results 6 weeks after the end of therapy showed highly significant reductions in social phobic fears and avoidance as well as in general anxiety and symptoms of depression. However, patients who dropped out during therapy reported a significantly higher degree of depression. Results did not differ between the four outpatient clinics and are comparable with the average effect-sizes reported by meta-analytic studies of controlled efficacy research, using selected patients. Also, restricting the sample according to the selection criteria often applied in research settings did not result in higher effect sizes for the applied outcome measures. We conclude that individual cognitive behavioural therapy for social phobia can be transported from research settings to the field of mental health.     

腔内激光疗法联合高位结扎治疗大隐静脉曲张疗效分析

比较大隐静脉腔内激光疗法（EVLT）联合高位结扎术与传统术式的临床疗效。选取大连医科大学附属第二医院2008年2月~2014年2月收治的大隐静脉曲张患者180例,采用EVLT的90例患者为激光组,采用传统高位结扎剥脱治疗的90例患者为对照组。激光组患者手术时间,切口数目及出血量优于对照组（P〈0.05）;两组总体VCSS计分差值、CEAP分布改变无差异,但伴静脉性溃疡病例,激光组VCSS计分差值优于传统组（P〈0.05）;两组术后并发症无差异。EVLT联合高位结扎术综合疗效明显优于传统术式,伴有静脉性溃疡的病例尤其明显。     

Does escape behaviour strengthen agoraphobic avoidance? A preliminary study

Two groups of agoraphobic patients were treated with one of two forms of exposure-based therapy. In one group, the patients stayed in the target situation until their self-rated anxiety dropped by half (Endurance condition). In the other, the patients were required to leave the fear situation when their anxiety reached a high pre-set level, without waiting for anxiety to drop (Escape condition). The patients in both groups improved, in contrast to those in a Waiting-list control group. There were no significant differences between the two treated groups. The results are discussed in terms of Mowrer's theory of fear and avoidance from which it can be predicted that patients in an ‘escape condition’ should not improve. Contrary to a Mowrerian prediction, patients who were taught to escape when still fearful, did not show increased avoidance behaviour.