Inter-individual and intra-individual variability of the N2 component: On reliability and signal-to-noise ratio

The nogo N2 component, an anterior negative peak supposed to be generated in the anterior cingulate cortex, has been used as an indicator of conflict monitoring and response conflict in basic and clinical research. Here, we investigate the reliability and the signal-to-noise ratio (SNR) of inter-individual differences of the N2 amplitudes as well as of intra-individual standard deviations of N2 amplitudes. Effects of the number of nogo epochs, type of summary measure (peak vs. average amplitude), and filter cut-offs (1–12 Hz vs. 1–30 Hz) are investigated. A sample of N = 32 participants, performed a go/nogo task. Excellent Cronbach’s alpha coefficients (?.90) were obtained for the fronto-central average N2 amplitude at 40 nogo epochs and for the peak N2 amplitude at 60 nogo epochs. The SNR was higher for the average nogo N2 amplitude compared to the peak N2 amplitude. Split-half reliability coefficients of the intra-individual standard deviation of the nogo N2 amplitudes were at least moderate. Based on these results we provide suggestions for a reliable N2 measurement. Moreover, although intra-individual variability has often been conceived as noise the present findings support the idea that intra-individual N2 variability incorporates systematic variance.     

Investigating the structure of autobiographical memory using reaction times

The study investigated the structure of autobiographical memory using reaction time measures. A total of 18 participants took photographs over their summer holidays and then reacted to pairs of these photographs displayed via a computer. They also subsequently sorted their photographs according to the autobiographical themes and events with which they were associated. When photographic sequence and the physical similarities in the photographs were controlled for by considering the results of “stranger” participants who were unfamiliar with the photographs, reaction times were significantly faster to pairs of photographs from the same theme or event. The results are consistent with currently held assumptions about the structure of autobiographical memory. Furthermore, the results suggest that reaction time measures may provide a valuable means by which aspects of autobiographical memory can be explored.     

Individuals differ in the attentional blink: Mental speed and intra-subject stability matter

The failure to correctly report two targets (“T₁”, “T₂”) that follow each other in close temporal proximity has been called the “attentional blink” (AB). The AB has, so far, mainly been studied using experimental approaches. The present studies investigated individual differences in AB performance, revealing (among further findings) a high positive correlation between the accuracies of detecting the two targets correctly (r = 0.69); and between T₂∣T₁ accuracy and psychometric intelligence (0.41 ≤ r ≤ 0.43) and RT variability in short-term and working memory (− 0.38 ≤ r ≤ − 0.45). Together, these results support important aspects of major theoretical accounts of the AB from an individual differences perspective and introduce intelligence and intra-subject stability as contributing factors in AB performance.     

Genetic and environmental contributions to the associations between intraindividual variability in reaction time and cognitive function

Intraindividual variability (IIV) in reaction time has been related to cognitive decline, but questions remain about the nature of this relationship. Mean and range in movement and decision time for simple reaction time were available from 241 individuals aged 51–86 years at the fifth testing wave of the Swedish Adoption/Twin Study of Aging. Cognitive performance on four factors was also available: verbal, spatial, memory, and speed. Analyses indicated that range in reaction time could be used as an indicator of IIV. Heritability estimates were 35% for mean reaction and 20% for range in reaction. Multivariate analysis indicated that the genetic variance on the memory, speed, and spatial factors is shared with genetic variance for mean or range in reaction time. IIV shares significant genetic variance with fluid ability in late adulthood, over and above and genetic variance shared with mean reaction time.     

Relationship between reaction time variability and motor skill development in ADHD

Slower and more variable reaction times to computerized tasks have been documented in children diagnosed with attention deficit/hyperactivity disorder (ADHD). Recent research supports a role for attentional lapses in generating abnormally variable and slow responses. However, given the association between ADHD and impairments in motor control, we hypothesized that slower or more variable reaction times might also correlate with motor development. The aim of this case-control study was to explore the relationship between motor function, reaction speed and variability, and ADHD. After comprehensive educational and clinical assessments, motor skill development was evaluated in 35 children ages 9 to 14 (19 with ADHD) using the Physical and Neurological Examination for Subtle Signs (PANESS) test battery. Finger-sequencing speed and variability were quantified with goniometers. Reaction times were measured with 20 trials each of computerized simple and choice (binary) tasks. Compared to healthy controls, children with ADHD had slower and more variable reaction times, and these findings correlated with impaired motor development (PANESS) and slow and variable finger sequencing (goniometers). Further studies of motor development in ADHD may identify factors influencing speed and variability of reaction times.     

Intra-individual reaction time variability in schizophrenia, depression and borderline personality disorder

Intra-individual reaction time variability (IIV) in neuropsychological task performance reflects short term fluctuations in performance. Increased IIV has been reported in patients with schizophrenia and could be related to a deficient neural timing mechanism, but the role of IIV in adult patients with other psychiatric disorders has not been established. Therefore, we compared IIV measures obtained in a Go/Nogo task from patients with schizophrenia, major depression and borderline personality disorder. IIV was increased for patients with schizophrenia. When correcting for differences in mean reaction time, depressive and borderline patients also showed increased IIV. Importantly, all groups showed a strong association between IIV and accuracy of task performance. This suggests that increased IIV might be a sensitive marker for the efficiency of top-down attentional control in all diagnostic groups. Aside from these similarities, the complete results including measures of IIV, mean reaction time and accuracy show differential patterns for patients with schizophrenia compared to those with borderline personality disorder or depression. These results are discussed with respect to common versus disorder-specific neural mechanisms underlying increased IIV.     

Methodological issues in measures of imitative reaction times

Ideomotor (IM) theory suggests that observing someone else perform an action activates an internal motor representation of that behaviour within the observer. Evidence supporting the case for an ideomotor theory of imitation has come from studies that show imitative responses to be faster than the same behavioural measures performed in response to spatial cues. In an attempt to replicate these findings, we manipulated the salience of the visual cue and found that we could reverse the advantage of the imitative cue over the spatial cue. We suggest that participants utilised a simple visuomotor mechanism to perform all aspects of this task, with performance being driven by the relative visual salience of the stimuli. Imitation is a more complex motor skill that would constitute an inefficient strategy for rapid performance.     

Lateralized effects of target location on reaction times when preparing for manual aiming at a visual target

To elucidate the temporal characteristics of information processing for motor action differing in complexity in relation to both perceptual and cognitive information processing, we investigated whether the reaction times (RTs) to a visual target would be affected by task complexity (finger lifting or manual aiming), pre-cueing (with a pre-cue or without a pre-cue), or target location (five horizontal positions). Using the right hand, seven right-handed subjects performed two tasks, finger lifting and manual aiming at a target, with or without a pre-cue. The pre-cue announced the location of the target to be presented. An ANOVA showed significant interactions between task and location and between pre-cue and location with no significant interaction between task and pre-cue, indicating that the task-location interaction does not depend on whether or not a pre-cue is given. The manual-aiming RTs were longer than the finger-lifting RTs, and the effects of the target location on the RTs differed for finger lifting and manual aiming. It can be assumed that the longer RTs of manual aiming reflect the time for information processing that is needed when preparing for the aiming action per se, which is an extra movement performed in addition to the simple initiation of finger lifting. Differential RTs (DRTs) calculated by subtracting the finger-lifting RTs from the aiming RTs were therefore examined. The DRTs significantly differed for target locations (i.e., a lateralized effect), with the DRTs for an ipsilateral target appearing to be significantly shorter than those for contralateral and central targets. The lateralized effect appearing on the DRTs may be mediated by the processing of visual-spatial information about visual targets as motor preparations are made for manual aiming.     

On the mean and variance of response times under the diffusion model with an application to parameter estimation

We give closed form expressions for the mean and variance of RTs for Ratcliff’s diffusion model [Ratcliff, R. (1978). A theory of memory retrieval. Psychological Review, 85, 59-108] under the simplifying assumption that there is no variability across trials in the parameters. These expressions are more general than those currently available. As an application, we demonstrate their use in a method-of-moments estimation procedure that addresses some of the weaknesses of the EZ method [Wagenmakers, E.-J., van der Maas, H. L. J., & Grasman, R. P. P. P. (2007). An EZ-diffusion model for response time and accuracy. Psychonomic Bulletin & Review, 14, 3-22], and illustrate this with lexical decision data. We discuss further possible applications.     

Affective variability in depression: Revisiting the inertia–instability paradox

How can depression be associated with both instability and inertia of affect? Koval et al. (2013, Emotion, 13, 1132) showed that this paradox can be solved by accounting for the statistical overlap between measures of affect dynamics. Nevertheless, these measures are still often studied in isolation. The present study is a replication of the Koval et al. study. We used experience sampling data (three times a day, 1 month) of 462 participants from the general population and a subsample thereof (N = 100) selected to reflect a uniform range of depressive symptoms. Dynamics measures were calculated for momentary negative affect scores. When adjusting for the overlap among affect dynamics measures, depression was associated with ‘dispersion’ (SD) but not ‘instability’ (RMSSD) or ‘inertia’ (AR) of negative affect. The association between dispersion and depression became non‐significant when mean levels of negative affect were adjusted for. These findings substantiate the evidence that the presumed association between depression and instability is largely accounted for by the SD, while the association between dispersion and depression may largely reflect mean levels of affect. Depression may thus not be related to higher instability per se, which would be in line with theories on the adaptive function of moment‐to‐moment fluctuations in affect.     

Display size effects in visual search: Analyses of reaction time distributions as mixtures

In a reanalysis of data from Cousineau and Shiffrin (2004) and two new visual search experiments, we used a likelihood ratio test to examine the full distributions of reaction time (RT) for evidence that the display size effect is a mixture-type effect that occurs on only a proportion of trials, leaving RT in the remaining trials unaffected, as is predicted by serial self-terminating search models. Experiment 1 was a reanalysis of Cousineau and Shiffrin's data, for which a mixture effect had previously been established by a bimodal distribution of RTs, and the results confirmed that the likelihood ratio test could also detect this mixture. Experiment 2 applied the likelihood ratio test within a more standard visual search task with a relatively easy target/distractor discrimination, and Experiment 3 applied it within a target identification search task within the same types of stimuli. Neither of these experiments provided any evidence for the mixture-type display size effect predicted by serial self-terminating search models. Overall, these results suggest that serial self-terminating search models may generally be applicable only with relatively difficult target/distractor discriminations, and then only for some participants. In addition, they further illustrate the utility of analysing full RT distributions in addition to mean RT.     

Recognition of all basic emotions varies in accuracy and reaction time: A new verbal method of measurement

To study different aspects of facial emotion recognition, valid methods are needed. The more widespread methods have some limitations. We propose a more ecological method that consists of presenting dynamic faces and measuring verbal reaction times. We presented 120 video clips depicting a gradual change from a neutral expression to a basic emotion (anger, disgust, fear, happiness, sadness and surprise), and recorded hit rates and reaction times of verbal labelling of emotions. Our results showed that verbal responses to six basic emotions differed in hit rates and reaction times: happiness > surprise > disgust > anger > sadness > fear (this means these emotional responses were more accurate and faster). Generally, our data are in accordance with previous findings, but our differentiation of responses is better than the data from previous experiments on six basic emotions.     

How to use the diffusion model: Parameter recovery of three methods: EZ, fast-dm, and DMAT

Parameter recovery of three different implementations of the Ratcliff diffusion model was investigated: the EZ model (Wagenmakers, van der Maas, & Grasman, 2007), fast-dm (Voss & Voss, 2007), and DMAT (Vandekerckhove & Tuerlinckx, 2007). Their capacity to recover both the mean structure and individual differences in parameter values was explored. The three methods were applied to simulated data generated by the diffusion model, by the leaky, competing accumulator (LCA) model (Usher & McClelland, 2001) and by the linear ballistic accumulator (LBA) model (Brown & Heathcote, 2008). Results show that EZ and DMAT are better capable than fast-dm in recovering experimental effects on parameters. EZ was best in recovering individual differences in parameter values. When data were generated by the LCA model, the diffusion model estimates obtained with all three methods correlated well with corresponding LCA model parameters. No such one-on-one correspondence could be established between parameters of the LBA model and the diffusion model.     

Responding to emotional scenes: effects of response outcome and picture repetition on reaction times and the late positive potential

Processing the motivational relevance of a visual scene and reacting accordingly is crucial for survival. Previous work suggests the emotional content of naturalistic scenes affects response speed, such that unpleasant content slows responses whereas pleasant content accelerates responses. It is unclear whether these effects reflect motor-cognitive processes, such as attentional orienting, or vary with the function/outcome of the motor response itself. Four experiments manipulated participants’ ability to terminate the picture (offset control) and, thereby, the response’s function and motivational value. Attentive orienting was manipulated via picture repetition, which diminishes orienting. A total of N?=?81 participants completed versions of a go/no-go task, discriminating between distorted versus intact pictures drawn from six content categories varying in positive, negative, or neutral valence. While all participants responded faster with repetition, only participants without offset control exhibited slower responses to unpleasant and accelerated responses to pleasant content. Emotional engagement, measured by the late positive potential, was not modulated by attentional orienting (repetition), suggesting that the interaction between repetition and offset control is not due to altered emotional engagement. Together, results suggest that response time changes as a function of emotional content and sensitivity to attention orienting depends on the motivational function of the motor response.     

Testing the hypothesized effect of dysgenic fertility on intelligence with existing reaction time data: A comment on Woodley,te Nijenhuis,and Murphy (2013)

Dysgenic fertility has supposedly resulted in a decline in general intelligence (g) over time. In light of evidence that simple visual reaction time (RT) is inversely related to IQ, Woodley et al. (2013) tested the hypothesized dysgenic effect by subjecting to a meta-regression simple visual RT data collected over 100 years in 15 studies. This analysis found that RT had significantly increased according to a linear function over this time period. Woodley et al. then used this result to estimate the rate at which g had declined over the same period. The present comment points out that there are large gaps in the distribution of RTs analyzed by Woodley et al. with respect to year tested, and that RT in males did not vary as a function of year in the 13 studies published from 1941 on. It is concluded that although existing data are consistent with the idea that g has been adversely affected by dysgenic fertility, it cannot be determined at what rate g has fallen over time.     

Estimating parameters of the diffusion model: approaches to dealing with contaminant reaction times and parameter variability

Three methods for fitting the diffusion model (Ratcliff, 1978) to experimental data are examined. Sets of simulated data were generated with known parameter values, and from fits of the model, we found that the maximum likelihood method was better than the chi-square and weighted least squares methods by criteria of bias in the parameters relative to the parameter values used to generate the data and standard deviations in the parameter estimates. The standard deviations in the parameter values can be used as measures of the variability in parameter estimates from fits to experimental data. We introduced contaminant reaction times and variability into the other components of processing besides the decision process and found that the maximum likelihood and chi-square methods failed, sometimes dramatically. But the weighted least squares method was robust to these two factors. We then present results from modifications of the maximum likelihood and chi-square methods, in which these factors are explicitly modeled, and show that the parameter values of the diffusion model are recovered well. We argue that explicit modeling is an important method for addressing contaminants and variability in nondecision processes and that it can be applied in any theoretical approach to modeling reaction time.     

Modelling the influence of time pressure on reaction time of drivers

Speeding is a major traffic violation and time pressure is one of the leading contributors to speeding. High-speed driving requires an immediate response to perilous events from the driver to avoid a crash. Reaction time is one of the important driving performance measures to assess the driver’s response to the event. Therefore, the current study examined the influence of time pressure on reaction times of the drivers measured for two different perilous events (pedestrians crossing and obstacle overtaking). Eighty-five Indian licensed drivers participated in a driving simulation study designed for three different time pressure conditions: No Time Pressure (NTP), Low Time Pressure (LTP), and High Time Pressure (HTP). The survival analysis technique was used to model the effect of time pressure and driver characteristics with reaction times of the drivers. It was observed that drivers’ reaction times decreased by 18% and 9% in LTP and 28% and 16% in HTP during the pedestrians crossing and obstacle overtaking events, respectively. Further, 1 m/second increase in approach speed resulted in 2% and 4% reduction in reaction times of the drivers in pedestrians crossing and obstacle overtaking events, respectively. Young drivers responded 21% faster than mature drivers during the pedestrians crossing event. Interestingly, sleeping hours and physical fitness played an important role in driver’s reaction to the events. The drivers performing regular physical exercise and having minimum eight-hours of overnight sleep reacted 16% and 17% earlier in pedestrians crossing and obstacle overtaking events, respectively. The overall findings from this study showed enhanced stimulus-response behaviour of the drivers under time pressure driving conditions. The results obtained from the study can give new insight into various safety-related ITS applications.     

Strategic flexibility in response preparation: Effects of cue validity on reaction time and pupil dilation

This study examined the ability of participants to strategically adapt their level of response preparation to the predictive value of preparatory cues. Participants performed the finger-precuing task under three levels of cue validity: 100, 75 and 50% valid. Response preparation was indexed by means of reaction time (RT) and pupil dilation, the latter providing a psychophysiological index of invested effort. Results showed a systematic increase in RT benefits (generated by valid cues) and RT costs (generated by invalid cues) with increments in the predictive value of cues. Converging with these behavioural effects, pupil dilation also increased systematically with greater cue validity during the cue-stimulus interval, suggesting more effortful response preparation with increases in cue validity. Together, these findings confirm the hypothesis that response preparation is flexible and that it can be strategically allocated in proportion to the relative frequency of valid/invalid preparatory cues.     

Prospective memory and intraindividual variability in ongoing task response times in an adult lifespan sample: the role of cue focality

To contribute to the ongoing conceptual debate of what traditional mean-level ongoing task (OT) costs tell us about the attentional processes underlying prospective memory (PM), we investigated costs to intraindividual variability (IIV) in OT response times as a potentially sensitive indicator of attentional processes. Particularly, we tested whether IIV in OT responses may reflect controlled employment of attentional processes versus lapses of controlled attention, whether these processes differ across adulthood, and whether it is moderated by cue focality. We assessed 150 individuals (19–82 years) in a focal and a nonfocal PM condition. In addition, external measures of inhibition and working memory were assessed. In line with the predictions of the lapses-of-attention/inefficient-executive-control account, our data support the view that costs to IIV in OT trials of PM tasks reflect fluctuations in the efficiency of executive functioning, which was related to failures in prospective remembering, particularly in nonfocal PM tasks, potentially due to their increased executive demands. The additional value of considering costs to IIV over and beyond traditional mean-level OT costs in PM research is discussed.     

Placing inspection time, reaction time, and perceptual speed in the broader context of cognitive ability: The VPR model in the Lothian Birth Cohort 1936

The idea that information processing speed is related to cognitive ability has a long history. Much evidence has been amassed in its support, with respect to both individual differences in general intelligence and developmental trajectories. Two so-called elementary cognitive tasks, reaction time and inspection time, have been used to compile this evidence, but most studies have used either one or the other. Relations between speed and fluid intelligence have tended to be stronger than those between speed and crystallized intelligence, but studies testing this have confounded verbal abilities with crystallized intelligence and spatial/perceptual abilities with fluid intelligence. Questions have also been raised regarding whether speed contributes directly to general intelligence or to more specific cognitive abilities to which general intelligence also contributes. We used 18 ability and speed measures in the Lothian Birth Cohort 1936, assessed at approximately age 70, to construct alternative versions of the Verbal-Perceptual-Image Rotation (Johnson & Bouchard, 2005a) model of cognitive ability to test different hypotheses regarding these issues. Though differences in the extents to which our models fit the data were relatively small, they suggested that reaction and inspection time tasks were comparable indicators of information processing speed with respect to general intelligence, that verbal and spatial abilities were similarly related to information processing speed, and that spatial, verbal, and perceptual speed abilities were more directly related to information processing speed than was general intelligence. We discuss the theoretical implications of these results.