Effects of overtraining on reversal learning by rats in concurrent and single discriminations

Two experiments examined the whole-partial effect of overtraining in concurrent discriminations and assessed the effect against single discrimination training in rats. In Experiment 1 overtraining facilitated reversal in Group W, in which rats were given concurrent training on two simultaneous discrimination tasks (A and B) in original learning before both tasks were reversed. By contrast, overtraining delayed reversal in Group P, in which animals were given the same training as in Group W in original learning, but only Task A was reversed. After overtraining, Group W reversed more rapidly than Group P. Without overtraining, Group P reversed more rapidly than both Group W and Group C, in which animals were trained only on Task A before this task was reversed. Experiment 2 investigated the effects of overtraining on the reversal of a successive discrimination in Groups W, P, and C. In addition, animals in a further group, Group S, received the same concurrent training as Group W before Task B was omitted and Task A reversed. Overtraining facilitated reversal in Groups W, C, and S but delayed it in Group P. After overtraining, Group W reversed more rapidly than Groups P, S, and C. Both Groups S and C also reversed more rapidly than did Group P. Without overtraining, Group P reversed more rapidly than Groups W, S, and C. There were no significant differences in reversal performance among Groups W, S, and C. These findings indicate that the effects of overtraining on reversal learning in concurrent discriminations differ from those observed in single discriminations.     

Differential effects of inactivation of the orbitofrontal cortex on strategy set-shifting and reversal learning

Different subregions of the rodent prefrontal cortex (PFC) mediate dissociable types of behavioral flexibility. For example, lesions of the medial or orbitofrontal (OFC) regions of the PFC impair extradimensional shifts and reversal learning, respectively, when novel stimuli are used during different phases of the task. In the present study, we assessed the effects of inactivation of the OFC on strategy set-shifting and reversal learning, using a maze based set-shifting task mediated by the medial PFC. Long–Evans rats were trained initially on a visual-cue discrimination to obtain food. On the subsequent day, rats had to shift to using a response strategy (e.g., always turn left). On Day 3 (reversal), rats were required to reverse the direction of their turn (e.g., always turn right). Infusions of the local anesthetic bupivacaine into the OFC did not impair initial visual discrimination learning, nor did it impair performance on the set-shift. In contrast, inactivation of the OFC did impair reversal learning; yet, these rats ceased using the previously acquired response rule as readily as controls. Instead, rats receiving OFC inactivations made a disproportionate number of erroneous arm entries towards the visual-cue, suggested that these animals reverted back to using the original visual-cue based strategy. These findings, in addition to previous data, further support the notion that the OFC and medial PFC play dissociable roles in reversal learning and set-shifting. Furthermore, the lack of effect of OFC inactivations on the set-shift indicates that this type of behavioral flexibility does not require cognitive operations related to reversal learning.     

Transfer of compounds and components in the discriminative learning of retardates

The discriminative learning and transfer of compound and component problems were assessed in retarded subjects at two levels of intelligence. It was found that brighter subjects (MA = 10 years) found the component problems relatively easier than the compound problems to a greater extent than did the less developed subjects (MA = 5 years). The learning of compound solutions was shown to transfer positively to other compound problems and negatively to component problems. Component solutions were found to transfer positively to other component solutions and negatively to compound solutions. These dimensional transfer effects were interpreted to mean that both compound and component solutions were mediated and conceptual in nature. The developmental differences in relative usages of compound and component aspects of stimuli were viewed as the result of differences in direction of attention rather than of differences in complexity of processing.