Inhibiting progesterone metabolism in the hippocampus of rats in behavioral estrus decreases anxiolytic behaviors and enhances exploratory and antinociceptive behaviors

Blocking progesterone’s metabolism to 5α -pregnan-3α -ol-20-one (3α ,5α -THP) with finasteride, a 5α -reductase inhibitor, and effects on anxiolytic, exploratory, and antinociceptive behaviors of rats in behavioral estrus were examined. Rats in behavioral estrus received finasteride systemically (SC), to the hippocampus, or to control implant sites, the nucleus accumbens (NA) or ventral tegmental area (VTA), and were tested in horizontal crossing, open-field, elevated plus-maze, emergence, holeboard, social interaction, tailflick, pawlick, and defensive freezing tasks. Finasteride, SC or intrahippocampally, reduced 3α ,5α -THP in the hippocampus relative to vehicle implants or finasteride to the NA or VTA. Systemic or intrahippocampal finasteride decreased central entries in the open field and open-arm time on the elevated plus-maze and increased freezing in response to shock relative to vehicle. Finasteride to the hippocampus decreased emergence latencies and increased social interaction, pawlick, and tailflick latencies relative to all other groups. Finasteride to the hippocampus of rats in behavioral estrous decreased anxiolysis and enhanced exploration and analgesia. In summary, these data demonstrate that decreases in anxiolytic behavior of behavioral estrous rats can be produced by reductions in 3α ,5α -THP in the hippocampus, which suggest that elevations in 3α ,5α -THP in the hippocampus may give rise to anxiolysis seen during behavioral estrus.     

Modulation of brain oscillations during fundamental visuo-spatial processing: A comparison between female collegiate badminton players and sedentary controls

ObjectivesThe present study aimed to investigate the difference in fundamental cognitive processing and neural oscillations between badminton players and sedentary controls.DesignA cross-sectional design was adopted to address this issue.MethodsWe compared time-frequency electroencephalographic (EEG) activity from collegiate female badminton players (n = 12, aged 20.58 ± 2.75 years) and age-and gender-matched sedentary non-athletic controls (n = 13, aged 19.08 ± 2.10 years) when they performed a task that involves visuo-spatial attention and working memory.ResultsWe observed that players responded faster than controls on the task without suffering any increase in error responses. Correspondingly, the players, relative to controls, exhibited higher task-related modulations in beta power in the attention condition as well as in theta and beta power in the working memory condition. Notably, the behavior-EEG correlations revealed that better attention performance is associated with lower beta power, while greater working memory is related to higher theta power.ConclusionsOur results shed light on the mechanisms of athletic superiority in fundamental cognitive functioning: the higher theta synchronization points to a greater engagement of attention, whereas the higher beta desynchronization supports the contribution of processing speed (or motor-related processing) to better performance in athletes. This study extends current understanding by suggesting that enhanced neurocognitive function seen in athletes may transfer to fundamental tasks, giving insight into the generalizability of sport experience to neurocognitive functioning.     

Psychological,social and physical environmental mediators of the SCORES intervention on physical activity among children living in low-income communities

ObjectivesThis study examined mediation effects of socio-ecological variables on accelerometer-determined physical activity among children in the Supporting Children's Outcomes using Rewards, Exercise and Skills (SCORES) intervention.DesignRandomized control trial mediation analysis.MethodsPrimary school children were randomly assigned the SCORES multi-component intervention or control group for the 12-month study. The outcome was accelerometer derived total moderate-to-vigorous physical activity (MVPA). Hypothesized mediators measured in children were physical activity enjoyment and perceived sport competence and social support. Hypothesized mediators measured in parents were family social support, access to physical activity facilities and equipment at home, and perceived access to physical activity opportunities in the local community. Mediation analyses were conducted using multi-level linear analysis in MPlus.ResultsThere were significant intervention effects for social support from teachers (A = 1.73, SE = 0.88, p = 0.048) and parental perceived access to physical opportunities in the local community (A = 2.69, SE = 1.12, p = 0.016). There were significant associations between changes in perceived sport competence (B = 0.48, SE = 0.36, p = 0.027), parental perceived access to physical activity opportunities in the local community (B = 0.60, SE = 0.26, p = 0.021), and changes in total MVPA. Parental perceived access to physical activity opportunities in the local community was found to have a significant mediating effect on total MVPA (AB = 1.61, 95% CI = 0.06 to 3.95, proportion 13%).ConclusionsParental perceived access to physical activity opportunities in the local community is a potential mechanism of behavior change for children and mediated the effect of the SCORES intervention on objectively measured physical activity.     

On unpredictability as a causal factor in “learned helplessness”

In two replications, two groups of dogs were exposed to a series of uncontrollable, electric shocks. For one group the shocks were preceded by a tone (i.e., Paired). For the other group the shocks were randomly related to the tones and hence unpredictable (i.e., Random). Each replication also included a third group; in the first it was exposed only to the series of tones (CS-only), while in the second, it was exposed only to a series of shocks (Shocks-only). Then, all dogs were required to learn a discriminative choice escape/avoidance task in which the required response was to lift the correct paw in the presence of each of two visual S^Ds to escape or avoid the shocks [($\text{S}{}_1{}^{\mathrm{D}}\text{?R}{}_1\text{)}\text{(S}{}_2{}^{\mathrm{D}}\text{?R}{}_2$)]. Dogs preexposed to random tones and shocks were least successful in learning the task relative to those groups which experienced either predicted shocks, only the tones, or only the shocks, which in turn did not differ from each other. These results permitted the inference that the proactive interference with choice behavior following random tone CSs and shocks was attributable to a learned irrelevance generalized with respect to CSs.     

Coping with Exposure to Violence: Relations to Emotional Symptoms and Aggression in Three Urban Samples

Relations among exposure to violence, coping, and adjustment were examined in three urban samples. In study 1, which took place in a southeastern city, children ages 6–16 (N = 35; M age = 10.7 years) completed measures of adjustment, exposure to violence, and coping with violence. In study 2, which took place in one southern Midwestern city and one Northeastern city, children ages 8–15 (N = 70; M age = 11.3 years) completed similar measures with the addition of a measure assessing normative beliefs about aggression. Results are in line with the pathologic adaptation model and provide preliminary evidence for two hypothesized pathways explaining the effects of exposure to violence on adjustment: a normalization pathway in which exposure leads to more aggression-supporting beliefs and in turn to greater aggression, and a distress pathway in which exposure leads to avoidant coping and in turn to emotional symptoms.     

Mental imagery increases self-determined motivation to exercise with university enrolled women: A randomized controlled trial using a peer-based intervention

ObjectivesThe purpose of this study was to examine the effects of a peer-based mental imagery intervention on the self-determined motivation and cardio-respiratory fitness of university enrolled women.DesignRandomized controlled trial.Method43 University enrolled women were randomized to peer-mentored or peer-mentored plus mental imagery conditions while 32 completed three meetings with peer-mentors and post-testing (M^age = 19.91; SD = 1.70).ResultsSignificant improvements in cardio-respiratory endurance, ratings of perceived endurance, and self-determined motivation to exercise were observed across both study conditions. Participants assigned to the peer mentored plus mental imagery condition reported significantly greater increases in self-determined motivation to exercise at post-test compared to those in the peer-mentored condition.ConclusionsPeer-based interventions are a viable way to improve fitness and health outcomes while mental imagery appears to be associated with increases in autonomous forms of exercise motivation.     

Modification of cooperation and aggression through teacher attention to children's speech

Two experiments were performed in the naturalistic setting of a preschool classroom in order to assess the effects on children's social behavior of nonevaluative teacher attention to children's cooperative or aggressive speech. In Experiment 1, teachers attended to the children's spontaneous cooperative speech for two weeks. Observation of the children's free-play behaviors revealed an increase over baseline levels in both verbal and physical cooperative behaviors as well as a decrease in both verbal and physical aggressive behaviors. In Experiment 2, teachers attended first to the children's spontaneous aggressive speech for one week and then switched their attention to the children's cooperative speech for a second week. Teacher attention to aggressive speech in the first week led to an increase over baseline levels in the children's verbal aggressive behavior as well as a decrease in both verbal and physical cooperative behaviors; however, physical aggression remained unchanged. Teacher attention to cooperative speech in the following week served to reverse the effects of the first week's treatment. The findings were discussed in terms of the sequential relationship between verbal and nonverbal components of cooperative and aggressive social behaviors and the teacher's role in modifying children's performance on these behaviors in the classroom.     

Strategies used by transmasculine and non-binary adults assigned female at birth to resist transgender stigma in healthcare

Abstract

Background: Transgender stigma is rampant within healthcare systems in the United States. Transgender adults assigned female at birth – including those identifying as transmasculine or non-binary – face unique barriers, such as stigma when accessing sexual and reproductive healthcare labeled as being for “women.” However, transgender and non-binary people are not passive victims to this stigma, and the medical community would benefit from understanding the actions this population takes to resist and reduce transgender stigma in healthcare. Yet, little research has attempted to understand such actions.

Aims: This qualitative study aims to explore how transmasculine and non-binary adults are actively resisting and reducing the impact of transgender stigma in healthcare.

Methods: In-depth semi-structured interviews were conducted with 25 transmasculine and non-binary adults assigned female at birth who were living in a metropolitan area in the mid-Atlantic United States. The research team analyzed qualitative interview data using content analysis.

Results: The 25 participants ranged in age from 21 to 57, with an average age of 33?years old. Six themes were identified related to resisting and reducing transgender stigma in healthcare: (a) using social support; (b) persistence to meet one’s own needs; (c) avoiding mainstream healthcare; (d) advocacy; (e) doing one’s own research; and (f) strategic disclosure of transgender/non-binary identity. We detail how privilege and intersectionality connect to the use of these strategies.

Discussion: Findings indicate there is value in using peer advocates and peer health literacy; in developing and nurturing support groups related to transgender/non-binary health; in developing “allies” employed within the healthcare system; in creating and maintaining lists of culturally responsive health providers and resources about navigating the healthcare system; and in offering trainings related to self-advocacy and health-related activism. These findings can be used to inform future health prevention and intervention efforts with transmasculine and non-binary adults.     

A critical examination of Michael Polanyi's conception of skills

In this paper I will consider some of the main issues in Michael Polanyi's discussion of ‘Skills’ from Chapter 4 of his book Personal Knowledge published in 1958.The concept of ‘skill’ features prominently in psychological theories of human performance in activities such as games, gymnastics, swimming and dance; such theories are often applied to other spheres of human activity in which issues about skill acquisition arise. It is not surprising to discover that skill theory is considered to be essential to the study of human movement and physical education. Physical education teachers in schools have consistently maintained that ‘skill acquisition’ is a major objective for the P.E. curriculum — see Kane 1974. Yet concepts such as ‘skill’, ‘ability’ and ‘know-how’ are constituent features of practical knowledge therefore the notion of ‘skill acquisition’ on its own will not do as a curriculum objective since all instances of skill and practical knowledge are specific to their contexts, namely, to different practical activities. If particular activities are valued in schools in the pursuit of children's learning and education it seems necessary to clarify the epistemological features of such activities in order to understand what it means to teach them and what it means for children to learn and know-how to perform them successfully. It is in these respects that the concept of ‘skill’ in different human activities should attract the interest of physical education students. In order to draw attention to major features of Polanyi's thesis on the nature of ‘skill’ I shall consider the relevance of his ideas about skill and knowledge in relation to human action theory. I suggest that misconceptions may arise in teaching and learning theories relating to ‘playing soccer’ if the basic underlying ideas about ‘skill’ in human activities are inconsistent with ideas about human action or, say, practical reasoning. It is this issue that is not, in my view, attended to by Polanyi in his discussion of ‘skill’. Thus, if my criticisms of Polanyi's ideas are shown to be valid it will be necessary, by implication that is, to exercise caution before any attempt is made to use his thesis as a basis from which to formulate ideas about teaching skills and skill acquisition. The extensive use I make of quotations from Polanyi's writings is necessary because it is towards Polanyi's use of language in his explanation of ‘skills’ that much of my criticism is directed. It is hoped that what follows may provide students of human movement and physical education with an insight into Polanyi's view of ‘skills’ in particular and to issues related to skill theory and human action in general.     

An evaluation of in situ training to teach sexual abuse prevention skills to women with mental retardation

The current study evaluated a behavioral skills training (BST) program in combination with in situ training to teach sexual abuse prevention skills to five women with mild to moderate mental retardation. In situ assessments were conducted following BST and in situ training sessions were conducted for those who were unable to demonstrate the skills in the natural setting. The results showed that generalization of the safety skills to the natural setting occurred for three of the five participants following one to two in situ training sessions. One participant required 12 in situ training sessions and three booster training sessions to reach criterion level. Three of four participants assessed 1 month following training maintained the skills. Copyright © 2007 John Wiley & Sons, Ltd.     

Strategic Maneuvering with the Intention of the Legislator in the Justification of Judicial Decisions

The author gives an analysis of the strategic manoeuvring in the justification of legal decisions from a pragma-dialectical perspective by showing how a judge tries to reconcile dialectical and rhetorical aims. On the basis of an analysis and evaluation of the argumentation given by the US Supreme Court in the famous Holy Trinity case, it is shown how in a case in which the judge wants to make an exception to a legal rule for the concrete case tries to meet the dialectical reasonableness norm by seeing to it that his standpoint is sufficiently defended according to the requirements of the burden of proof of a judge in a rational critical discussion and how he tries at the same time to be rhetorically convincing for the legal audience by presenting the decision as a choice that is in line with the argumentation schemes and starting points that can be considered as accepted by the legal community in the US and by the US community as a whole.

The scientific use of ‘representation’ and ‘function’: avoiding explanatory vacuity

Nearly all of the ways philosophers currently attempt to define the terms ‘representation’ and ‘function’ undermine the scientific application of those terms by rendering the scientific explanations in which they occur vacuous. Since this is unacceptable, we must develop analyses of these terms that avoid this vacuity. Robert Cummins argues in this fashion in Representations, Targets, and Attitudes. He accuses ‘use theories’ of representational content of generating vacuous explanations, claims that nearly all current theories of representational content are use theories, and offers a non-use theory of representational content which avoids explanatory vacuity. One task I undertake in this article is to develop an alternative non-use theory which avoids an objection fatal to that theory. My second task is to adapt Cummins’ argument to criticize most current analyses of ‘function,’ which undermine scientific explanation in an analogous way. Though Cummins does not explicitly argue in this manner, his own analysis of ‘function,’ by avoiding any appeal to use, avoids the explanatory vacuity to which they succumb. Consequently, I endorse Cummins’ notion of function. However, although use theories fail as analyses of the terms ‘representation’ and ‘function,’ they can still make significant contributions to the sciences employing these terms. For, while philosophers seeking to define ‘representation’ and ‘function’ must avoid incorporating representational and functional uses into their definitions, scientists must still find a way to determine which representations and functions are being used. Suitably re-construed use theories of representation and function may in many cases assist them in this task.     

Sick? Or slow? On the origins of intelligence as a psychological object

This paper examines the first moments of the emergence of “psychometrics” as a discipline, using a history of the Binet–Simon test (precursor to the Stanford–Binet) to engage the question of how intelligence became a “psychological object.” To begin to answer this, we used a previously-unexamined set of French texts to highlight the negotiations and collaborations that led Alfred Binet (1857–1911) to identify “mental testing” as a research area worth pursuing. This included a long-standing rivalry with Désiré-Magloire Bourneville (1840–1909), who argued for decades that psychiatrists ought to be the professional arbiters of which children would be removed from the standard curriculum and referred to special education classes in asylums. In contrast, Binet sought to keep children in schools and conceived of a way for psychologists to do this. Supported by the Société libre de l'étude psychologique de l'enfant [Free society for the psychological study of the child], and by a number of collaborators and friends, he thus undertook to create a “metric” scale of intelligence—and the associated testing apparatus—to legitimize the role of psychologists in a to-that-point psychiatric domain: identifying and treating “the abnormal”. The result was a change in the earlier law requiring all healthy French children to attend school, between the ages of 6 and 13, to recognize instead that otherwise normal children sometimes need special help: they are “slow” (arriéré), but not “sick.” This conceptualization of intelligence was then carried forward, through the test's influence on Lewis Terman (1877–1956) and Lightner Witmer (1867–1956), to shape virtually all subsequent thinking about intelligence testing and its role in society.     

Réflexions critiques sur les notions d’abolition et d’altération de la faculté à discerner

Inasmuch as the constitution of the mens rea of any offence remains suspended to its integrity, the capacity for discernment represents a condition of accountability whose definition responds to issues that are as much technical – with respect to psychiatric and psychological penal expertise – as they are theoretical – with respect to our conception of criminal responsibility and the psychological prerequisites that underlie it. Now, the fact is that since its introduction in 1992 with article 122–1 of the Penal Code, this notion of discernment is characterized by a certain conceptual inconsistency, giving rise to a damaging plurality of meanings making the verb discern the condensed version of a heterogeneous network of distinct psychological functions. The polysemic term of discernment thus gives rise to a fundamental indetermination as to the nature of the faculty that must be examined in order to decide on its abolition or its preservation at the moment of the act. This is not without favouring the appearance and persistence of arbitrary interpretations, and consequently discordant expert conclusions. Even more problematic, however, is the idea of an alteration of discernment, given the irreducible discrepancy between the continuous nature of an alteration and the discontinuous nature of the conclusion to which the agent is subject, in that the legal demand requires a decision – in a discretization of what is continuous – between the presence and absence of something that is lacking. We will in fact show in what way this concept of alteration as it applies to discernment tends to be either meaningless, or redundant – and therefore useless – in relation to that of abolition. So much so that the only conceivable solution to maintain a certain gradation of degrees of non-accountability seems to consist in having to specify the different types of abolition of discernment potentially observed, and then to propose a hierarchization according to their greater or lesser compatibility with the conservation of a criminal responsibility. .     

The being-with of being-there

In Being and Time, Heidegger affirms that being-with or Mitsein is an essential constitution of Dasein but he does not submit this existential to the same rigorous analyses as other existentials. In this essay, Jean-Luc Nancy points to the different places where Heidegger erased the possibility of thinking an essential with that he himself opened. This erasure is due, according to Nancy, to the subordination of Mitsein to a thinking of the proper and the improper. The polarization of Being-with between an improper face, the Anyone, and a proper one, the people, which is also, as Nancy shows, a polarization between everydayness and historicity, between a being-together in exteriority (indifference and anonymity) and a being-together in interiority (union through destiny), between a solitary dying and the sacrificial death in combat, leaves the essential with unthought. This essay shows not only the tensions that arise out of Heidegger’s own analyses of Mitsein and affect the whole of Being and Time but also underlines in the end a “shortfall in thinking” inherent not only to Heidegger’s work but, as Nancy claims, to our Western tradition, a shortfall which Nancy has attempted to remedy in his Being Singular Plural. A slightly different version has been published under the title “L’être-avec de l’être-là” in Lieu-Dit 19 “Communauté” (Spring 2003). All additions in square brackets are the translators’ unless otherwise indicated. The German words in parentheses are Nancy’s additions. For the translation of citations from Being and Time, we have used the Macquarrie & Robinson’s translation which we have modified only when constrained by Nancy himself. Overall, we have tried to be faithful to the Heideggerian tone of Nancy’s text by using the accepted English translation of the central concepts of Being and Time. When we depart from the accepted translations, it is to remain true to Nancy’s paraphrases, emphases, and displacements. For example, we refrain from using “authentic” and “inauthentic.” Translated by Marie-Eve Morin Department of Philosophy, 4-97 Humanities Centre, University of Alberta, Edmonton, AB, Canada T6G 2E5 e-mail: mmorin1@ualberta.ca

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On the irreducibility of the will

This paper criticizes the thesis that intending to do something is reducible to some combination of beliefs and desires. Against Audi's recent formulation of such a view I offer as counterexample a case wherein an agent who wants and expects to V has not yet decided whether to V and hence does not yet intend to. I try to show that whereas belief that one will V is not necessary for intending to V, as illustrated in cases of desperate attempts to V, one cannot intend to V without preferring to V (rather than not V) and thus one cannot intend to V without, in some sense, wanting to V (at least wanting it in preference to not V-ing). The connection of one's intentions with one's objectives, attempts, plans, and hopes is briefly treated, and some influential work by Davidson is criticized.     

Évaluation des dimensions psychopathiques sur le mode d’adaptation carcérale

IntroductionThe disorders associated with the coping styles of detainees in prisons, including the interaction between individual and the environment, can be approached in two ways. Either as the result of a normal reaction of prisoners with regard to specific components in a pathogenic environment, or resulting from psychopathological determinants inherent to inmates prior to incarceration.ObjectivesThis study aims to measure the impact of components related to personality traits deemed stable and observed among inmates in regards to their modes of adaptations to the prison environment. More specifically, observing the types of adaptation of prisoners, according to their scores on the Hare psychopathy checklist (PCL-R).MethodsThe study is based on a series of interviews conducted on a sample of 26 inmates in three different detention centers located in France.ResultsThe results show a strong relationship between some psychopathic dimensions and characteristics of conduct disorder or disciplinary offenses in prison. High scores in both factor 1 (interpersonal and emotional relationship) and factor 2 (social deviance) strongly correlates with disciplinary problems such as heteroaggressive violence towards staff or other inmates. While a high score of factor 2 only increases the risk of disciplinary problems, such as group violence or involvement in trafficking.ConclusionsThe presence or absence of certain personality traits that characterize psychopathy could determine how an inmate would adapt to the prison environment.     

Why is number word learning hard? Evidence from bilingual learners

Young children typically take between 18 months and 2 years to learn the meanings of number words. In the present study, we investigated this developmental trajectory in bilingual preschoolers to examine the relative contributions of two factors in number word learning: (1) the construction of numerical concepts, and (2) the mapping of language specific words onto these concepts. We found that children learn the meanings of small number words (i.e., one, two, and three) independently in each language, indicating that observed delays in learning these words are attributable to difficulties in mapping words to concepts. In contrast, children generally learned to accurately count larger sets (i.e., five or greater) simultaneously in their two languages, suggesting that the difficulty in learning to count is not tied to a specific language. We also replicated previous studies that found that children learn the counting procedure before they learn its logic – i.e., that for any natural number, n, the successor of n in the count list denotes the cardinality n + 1. Consistent with past studies, we found that children’s knowledge of successors is first acquired incrementally. In bilinguals, we found that this knowledge exhibits item-specific transfer between languages, suggesting that the logic of the positive integers may not be stored in a language-specific format. We conclude that delays in learning the meanings of small number words are mainly due to language-specific processes of mapping words to concepts, whereas the logic and procedures of counting appear to be learned in a format that is independent of a particular language and thus transfers rapidly from one language to the other in development.     

Susceptibility to filmed models: A study of aggressive and constructive imitation

This study supports the view that young boys are, to some degree, consistent in their tendency to be influenced by what they have seen on films. Seventy-two boys were assigned randomly to an ‘aggressive’ film, a ‘constructive’ film, or a ‘mixed’ condition, in which they saw two ‘aggressive’ films, two ‘constructive’ films or one ‘aggressive’ and one ‘constructive’ film. The number of acts a boy imitated after seeing one film was positively correlated with the number of acts imitated after viewing the second film in all three conditions. This tendency is shown to be independent of the initial tendency to act in the way portrayed in the film. Further research into the question of individual differences in the tendency to imitate filmed behaviour is encouraged.     

Rats’ novel object interaction as a measure of environmental familiarity

Environmental familiarization is a learning phenomenon embedded within most tasks used to study learning and motivation. Given its prevalence there is surprisingly little systematic behavioral research on factors affecting familiarization. The six experiments reported in the present report used rats’ tendency to interact more with a novel object in a familiar than in a novel environment as a measure of environmental familiarization. We found that 3 min of exposure to the environment was sufficient to increase object interaction above unfamiliar controls even when testing occurred up to 48 h after initial exposure to the environment; 1 or 1.5 min of exposure was not sufficient. Also, in the brief 2 min test, 10 min of environment exposure did not appear to increase object interaction above the 3-min condition. The 3-min of environment exposure was sufficient for familiarization whether environment exposure occurred in one 3 min placement or two 1.5 min placements. Environmental familiarization as measured by object interaction was also sensitive to ‘interference’ manipulations. That is, a distinct object present during initial exposure to the environment produced a level of object interaction in testing comparable to an unfamiliar control. Similarly, exposure to a second distinct alternate environment immediately after, but not before, initial exposure to the test environment partially disrupted environmental familiarization. In sum, object interaction might serve as a useful measure for studying processes mediating environmental familiarity.