Sociology and psychology within the scope of scientific dishonesty

A survey is undertaken based on qualitative analyses of the cases of scientific misconduct from the Danish Committee on Scientific Dishonesty’s first five years of collecting data, with additional information from selected international sources, in which underlying psychological motivations can be judged. An carlier version of this paper was presented at a symposium, Scientific Misconduct. An International Perspective, organised by The Medical University of Warsay, 16 November, 1998.     

Effectiveness of research guidelines in prevention of scientific misconduct

In response to a series of allegations of scientific misconduct in the 1980’s, a number of scientific societies, national agencies, and academic institutions, including Harvard Medical School, devised guidelines to increase awareness of optimal scientific practices and to attempt to prevent as many episodes of misconduct as possible. The chief argument for adopting guidelines is to promote good science. There is no evidence that well-crafted guidelines have had any detrimental effect on creativity since they focus on design of research studies, documentation of research findings, assignment of credit through authorship, data management and supervision of trainees, not on the origin and evolution of ideas. This paper addresses a spectrum of causes of scientific misconduct or unacceptable scientific behavior and couples these with estimates of the potential for prevention if guidelines for scientific investigation are adopted. The conclusion is that clear and understandable guidelines should help to reduce the chance that flawed research will escape from our institutions. However, they cannot be relied upon alone to prevent all instances of scientific misconduct and should be regarded rather as one means of bolstering the integrity of the entire scientific enterprise.     

Guidelines for training in the ethical conduct of scientific research

Historically, scientists in training have learned the rules of ethical conduct by the example of their advisors and other senior scientists and by practice. This paper is intended to serve as a guide for the beginning scientist to some fundamental principles of scientific research ethics. The paper focuses less on issues of outright dishonesty or fraud, and more on the positive aspects of ethical scientific behavior; in other words, what a scientist should do to maintain a high level of ethical conduct in research. There are a number of fairly specific rules, guidelines, or commonly accepted operating principles that have evolved for the ethical conduct of science. In order to discuss this code of ethics, this paper is divided into sections dealing with specific areas of scientific ethics. These areas are: data collection and storage, ownership of data, confidentiality, communication, authorship, collaboration, the peer review system, and rules of dealing with ethical complaints. Illustrative case histories are presented to provide examples of the type of ethical dispute or problem being discussed. If scientific trainees learn the accepted rules of behavior that govern the conduct of science, ethical problems that arise out of ignorance, misunderstanding, or poor communication can be avoided.     

谈谈中国临床试验研究中受试者权益保障问题

随着国家《药品临床试验管理规范》的颁布与实施,我国新药临床试验研究水平有相当的提高,但也存在着一些问题。其中包括保护受试者权益问题。国家GCP有关章节中明确指出要保护受试者权益。并有具体规定,但在执行中尚有出入,如试验方案未经伦理委员会批准,未向受试者告知试验内容。或告知的不够充分,甚至在未签署知情同意书时就开始试验等。为此,我国采取了相应的措施,如设立药品临床研究培训中心;定期对临床试验基地的研究者以及相关人员如与试验有关的医师,药师及申办者进行GCP培训,基地审核制度,以法律手段来保证受试者权益等。     

Ethical Academic Judgments and Behaviors: Applying a Multidimensional Ethics Scale to Measure the Ethical Academic Behavior of Graduate Students

Using Reidenbach and Robin's Multidimensional Ethics Scale, this study investigated the relationships between background variables and students' ethical evaluations, judgments, and behavioral intentions using 3 scenarios involving dilemmas related to academic dishonesty. The sample included 436 master's students and 142 doctoral students. The study found that the participants used a combination of ethical philosophies to make ethical decisions. The respondents judged improper citations more harshly than acts of inappropriate authorship or the falsification of data. The doctoral students generally considered behaviors related to plagiarism and falsification to be more unethical than the master's students did, though no gender differences were found.     

From stratospheric ozone to climate change: Historical perspective on precaution and scientific responsibility

The issue of the impact of human activities on the stratospheric ozone layer emerged in the early 1970s. But international regulations to mitigate the most serious effects were not adopted until the mid-1980s. This case holds lessons for addressing more complex environmental problems. Concepts that should inform discussion include “latency,’ ‘counter-factual scenario based on the Precautionary Principle,’ ‘inter-generational burden sharing,’ and ‘estimating global costs under factual and counter-factual regulatory scenarios.’ Stringent regulations were adopted when large scientific uncertainty existed, and the environmental problem would have been prevented or more rapidly mitigated, at relatively modest incremental price, but for a time delay before more rigorous Precautionary measures were implemented. Will history repeat itself in the case of climate change?     

从权利意识的视角看实践患者知情同意的文化障碍

实现知情同意权是对患者自主权利的尊重,但患者知情同意权的实现遇到诸多的文化障碍,从权利意识的视角看,主要来自于中国的一元社会结构、儒家文化和法律文化传统对个人权利诉求的影响,只有培养和提高患者权利意识,增强主体性和自主性,消除文化障碍,才能真正落实知情同意权。     

When a bystander becomes an accomplice: Situational determinants of reactions to dishonesty

In a series of experiments, undergraduates (N = 288) performed a task with a confederate who subsequently lied about his or her performance in order to obtain a cash bonus. The probability of bystanders' reporting the dishonesty and refusing to sign a document attesting to the confederate's score was differentially affected by situational factors and sex of the bystander, wrongdoer, and authority figure. Bystanders were most apt to report the misdeed when they were competing against rather than working either independently or cooperatively with the culprit, at least when the bonus was provided by a large corporation. In addition, females were more likely than males to report when the victim was another person rather than either a corporation or the bystander himself, and both sexes were more apt to report a female wrongdoer than a male one. Persons who initially reported the misdeed were less likely to become active accomplices than were those who failed to report it. Furthermore, less written verification of the falsehood occurred when (a) nonreporters were performing independently rather than either competing against or working cooperatively with the culprit for the bonus, and (b) a male was in an immediate position of authority.     

Mobilizing positive reinforcement in communities to reduce youth access to tobacco

A community intervention to mobilize positive reinforcement for not selling tobacco to young people was evaluated. The intervention had five components: (a) mobilization of community support, (b) merchant education, (c) changing consequences to clerks for selling or not selling to those under 18, (d) publicity about clerks’ refusals to sell, and (e) feedback to store owners or managers about the extent of their sales to adolescents. A multiple baseline design experiment was conducted, in which two small Oregon communities received the intervention, while two others continued in baseline. Outlets’ willingness to sell was assessed repeatedly by teenage volunteers. The intervention significantly reduced the proportion of stores willing to sell. Mobilizing socia and material reinforcement for stores not selling tobacco to young people is a viable means of reducing such sales. It may be especially valuable in communities where laws against sales to minors go unenforced. This paper supported in part by the National Cancer Institute Grant CA38273.     

Three Views of Artful Practice in Psychosocial Occupational Therapy

This qualitative study explored artfulness in the psychosocial practice of three occupational therapists through in-depth observation and interviews. Analysis focused on the therapist-client relationship, activity use, self-reflection, and the change process. Each therapist established an interpersonal connection while offering meaningful, engaging activities. In addition, each brought a distinct and unique personal view to treatment. Findings suggest that the art of practice in occupational therapy is constructed by the therapist's integrated balance of substance, form, and vision to achieve a coherent whole, which positively influences the personal views of substance, form, and vision in clients.     

Three Conceptual Models of Patient and Public Involvement in Standard-setting: From Abstract Principles to Complex Practice

Clinical practice guidelines have been critiqued for prescribing standardized care that neglects patients’ personal circumstances and knowledge in health care decisions. To make care more patient centred, standard-setters are urged to involve patients and the public in guideline development and use. Despite widespread principled support for such Patient and Public Involvement (PPI), the underlying principles guiding PPI in standardization of care are mired on confusion and contradiction. Based on the PPI literature in general, and informed by empirical research on guideline development, it is possible to identify three rationales that justify PPI in clinical standard setting. Each rationale gives rise to a conceptual model which outlines a distinct purpose of participation, who is to be included, and what they are expected to contribute. The Consumer Choice model aims to involve autonomous consumers to personalize clinical care. The Democratic Voice model aims for health care recommendations to better reflect collective values of citizens. The Lay Expertise model aims to re-contextualize universal evidence by including experiential patient knowledge. However, these models can and should not function as ‘Gold Standards’ to be consistently followed in practice. First, the models rely on two distinct types of representation, resulting in contradictory notions of how to be a good representative. Second, imposing models on practice requires a top-down control that is practically and politically problematic. Not only is control difficult to achieve, it may compromise the participatory ideal of participants co-determine practice, and may result in excluding the values and views of ‘real’ patients and public entirely.     

From the Roots of Psychosocial Practice-Therapeutic Use of Self in the Classroom: Practical Applications for Occupational Therapy Faculty

The roots of occupational therapy stem from psychosocial practice and embrace concepts of humanism, client-centered practice and therapeutic use of self. These concepts are integral to both clinical and academic settings. As the profession has moved toward graduate level education, increased numbers of non-traditional students are entering the field. Models of teaching that incorporate principles of active learning and therapeutic use of self within the classroom provide a consumer-learner-based model of education that is uniquely suited to students of diverse backgrounds, lifestyles, and educational needs. This article presents a brief overview of andragogical principles and the development of the student-faculty relationship. Mosey's concepts of conscious use of self are introduced as a means by which positive faculty-student relationships can be formed in order to enhance student learning and educational outcomes.     

Sensitivity to the Sampling Process Emerges From the Principle of Efficiency

Humans can seamlessly infer other people's preferences, based on what they do. Broadly, two types of accounts have been proposed to explain different aspects of this ability. The first account focuses on spatial information: Agents' efficient navigation in space reveals what they like. The second account focuses on statistical information: Uncommon choices reveal stronger preferences. Together, these two lines of research suggest that we have two distinct capacities for inferring preferences. Here we propose that this is not the case, and that spatial‐based and statistical‐based preference inferences can be explained by the assumption that agents are efficient alone. We show that people's sensitivity to spatial and statistical information when they infer preferences is best predicted by a computational model of the principle of efficiency, and that this model outperforms dual‐system models, even when the latter are fit to participant judgments. Our results suggest that, as adults, a unified understanding of agency under the principle of efficiency underlies our ability to infer preferences.     

From individual to group impressions: Availability heuristics in stereotype formation

When subjects are presented with information about the attributes of individuals and are then asked to make judgments about the characteristics of the group composed of those individuals, the group impression may depend on the way in which data on individuals are organized in memory. Experiment 1 demonstrated that under conditions of low memory load (16 instances of person-trait pairings), subjects organize their perceptions of a group around the characteristics of its individual members, whereas under high memory load (64 instances of person-trait pairings), subjects organize trait information in an undifferentiated way around the group as a whole. Under low memory load, subjects distinguish between repeated occurrences of a trait in the same individual and comparable repeated occurrences of that trait in different individuals; under high memory load, subjects do not make such a differentiation. Subjects' judgments about the frequency of categories of traits were related to the ease of recall of category instances, as predicted by an availability heuristic. Experiments 2 and 3 demonstrated that group members who are most available in memory will be disproportionately represented in the group impression. Specifically, the proportion of extreme individuals in a group was retro-spectively overestimated; this was true for both physical stimuli (height) and social stimuli (criminal acts).     

Social Research in the Advancement of Children's Rights

This article argues that investigators doing developmental and social research with children have, for the most part, failed to acknowledge the inherent implications of their work for children's rights. The impact of these studies upon children's rights occurs at every stage; from hypothesis formulation to hypothesis testing to dissemination of findings. This paper addresses the issue in the context of developmental research on children's ability to report experienced events accurately. This particular research area has generated data that has been extrapolated to legal contexts and created a foundation for assumptions about the credibility of child witnesses. This in turn has had profound effects on children's right to be heard and the weight given to their testimony. The argument is made that there is a need for social scientists to explicitly articulate how their work may impact upon children's rights and what is in fact the social agenda in this regard underlying their research.     

From dispositions to behaviors: The flip side of attribution

The implicational relations between dispositional levels and relevant categories of behavior were investigated. Observers were asked questions about the extent to which persons occupying moderate or extreme positions on an attribute (dispositional) continuum (a) attempt various behaviors, (b) are potentially able to perform various behaviors, and (c) generally emit those same behaviors. Three determinants—central tendency, ability, and social desirabliity—offer a reasonable account of the observed implicational relations. First, persons with a given disposition are not expected to emit behavior that is widely discrepant with that disposition. Second, ability considerations dictate that persons with skillful dispositions are believed capable of unskillful behavior, but unskillful persons are thought relatively incapable of skillful behavior. Third, persons are believed to more frequently attempt socially desirable than socially undesirable behavior. Also, persons with moderate dispositions are believed to actually emit socially desirable behavior more frequently than socially undesirable behavior. Finally, the determinants noted above may be of differing relevance for morality, ability, and preference attributes.     

Fabry disease in genetic counseling practice: recommendations of the National Society of Genetic Counselors

The objective of this document is to provide health care professionals with recommendations for genetic counseling and testing of individuals with a suspected or confirmed diagnosis of Fabry disease, with a family history of Fabry disease, and those identified as female carriers of Fabry disease. These recommendations are the opinions of a multicenter working group of genetic counselors, medical geneticists, and other health professionals with expertise in Fabry disease counseling, as well as an individual with Fabry disease who is a founder of a Fabry disease patient advocacy group in the United States. The recommendations are U.S. Preventive Task Force Class III, and they are based on clinical experience, a review of pertinent English-language articles, and reports of expert committees. This document reviews the genetics of Fabry disease, the indications for genetic testing and interpretation of results, psychosocial considerations, and references for professional and patient resources. These recommendations should not be construed as dictating an exclusive course of management, nor does use of such recommendations guarantee a particular outcome. The professional judgment of a healthcare provider, familiar with the facts and circumstances of a specific case, will always supersede these recommendations.