Recognition of facial expressions of different emotional intensities in patients with frontotemporal lobar degeneration

Behavioural problems are a key feature of frontotemporal lobar degeneration (FTLD). Also, FTLD patients show impairments in emotion processing. Specifically, the perception of negative emotional facial expressions is affected. Generally, however, negative emotional expressions are regarded as more difficult to recognize than positive ones, which thus may have been a confounding factor in previous studies. Also, ceiling effects are often present on emotion recognition tasks using full-blown emotional facial expressions. In the present study with FTLD patients, we examined the perception of sadness, anger, fear, happiness, surprise and disgust at different emotional intensities on morphed facial expressions to take task difficulty into account. Results showed that our FTLD patients were specifically impaired at the recognition of the emotion anger. Also, the patients performed worse than the controls on recognition of surprise, but performed at control levels on disgust, happiness, sadness and fear. These findings corroborate and extend previous results showing deficits in emotion perception in FTLD.     

Dreaming and cognition in patients with frontotemporal dysfunction

Individuals with Parkinson’s disease (PD) and temporal lobe epilepsy (TLE) have hallucinations and mild cognitive dysfunction. The objective of this work was to study dreams in PD and TLE patients using a common functional model of dream production involving the limbic and paralimbic structures.Dreams were characterised in early-stage PD (19 males) and TLE patients (52) with dream diaries classified by the Hall van de Castle system and were compared with matched controls.In PD, there were significant differences between patients’ dreams and those of controls: animals, physical aggression, and a befriender were more common in patients, and aggressor and bodily misfortunes were less common. The dreams of patients with frontal dysfunction showed more aggressive features.TLE patients had lower recall than PD patients and a higher proportion of dreams involving family and familiar settings, lower proportions involving success, and a higher incidence of frontal dysfunction.The dreams of PD and TLE patients share important features.     

Neurolinguistic analysis of verbal utterances in patients with focal lesions of frontal lobes

Verbal utterances of 105 patients have been analyzed. Six groups of subjects were examined including patients with left dorsolateral frontal lesions, left orbitofrontal lesions, right frontal lobe lesions, posterior aphasics, posterior brain-damaged patients without aphasia, and a matched control group. Results indicate that the left frontal lobe is involved in organization of linguistic information. Its dorsolateral part seems to be concerned with forming the sequential pattern of an utterance, and the orbital part with the directed development of a narrative. It is conceivable that the right frontal lobe is important for the global, nonlinguistic organization of information to be uttered.     

Semantic processing in patients with Alzheimer's disease

Ten patients with dementia of the Alzheimer type and 10 normal controls performed a lexical decision, semantic facilitation task. The performance of the patients differed from that seen in normals. A post hoc subdivision of the data suggested that the diviation from normality was not uniform throughout the patient population. Six of the 10 Alzheimer patients showed an advantage of related primes over unrelated primes, while 4 of the 10 were actually faster in the unrelated condition than in the related condition. Nevertheless, both group of Alzheimer patients showed lexical decision latency differences between unrelated and related prime words, suggesting that patients with Alzheimer's disease are sensitive to the semantic relationships between words.     

Construct asymmetry and the range of relevance of personal anticipations

This paper analyses the logical structure of personal construct systems in terms of relations of partial entailment between constructs and the relative frequencies of positive and negative judgments concerning both self and others. It is argued that conditional hypotheses (‘anticipations’) which incorporate the positive poles of constructs (e.g. happy) as antecedent terms will have wider ranges of relevance, on average, if self is assigned to the positive poles of those constructs. Conversely, hypotheses with antecedents based on the negative poles of constructs (e.g. sad) will tend to have wider ranges of relevance when self is assigned to their negative poles. Some theoretical implications of these relationships for the adaptability of personal construct systems are elaborated.     

Problems inhibiting attentional capture by irrelevant stimuli in patients with frontotemporal dementia

We studied the role of the frontal lobes in orienting spatial attention and inhibiting attentional capture by goal-irrelevant stimuli, using a spatial cueing method in patients with frontotemporal dementia (FTD). Two blocks of trials were presented, one with non-predictive cues and the other with counter-predictive cues. FTD patients showed a global orienting deficit, with a greater difference between invalid and valid trials than age-matched controls. However, they were able to use the (counter-) predictiveness of the cue to reduce the invalid/valid difference when targets occurred most often in the location opposite the cue. Thus, endogenous control of attention in our FTD patients was sufficient to reorient attention on the basis of the probability of events, but not to resist the capture of attention by goal-irrelevant stimuli. These results confirm the role of frontal lobes in the inhibition of attentional capture.     

Studying social cognition in patients with schizophrenia and patients with frontotemporal dementia: theory of mind and the perception of sarcasm

We investigated social cognition and theory of mind in patients with schizophrenia and in patients with frontotemporal dementia in order to elucidate the cognitive mechanisms involved in the breakdown of these skills in psychiatric and neurological patients. Our tasks included videotaped scenarios of social interactions depicting sincere, sarcastic and paradoxical remarks, as well as lies. We found impaired performance of the schizophrenia group on all theory of mind conditions despite their intact understanding of sincere statements. In contrast, the FTD group performed poorly only when they had to rely on paralinguistic cues indicating sarcasm or lies, and not on paradoxical remarks or sarcasm when given additional verbal cues. Our findings suggest that, while current deficits in social and interpersonal functioning in patients with FTD may reflect a decrement in previously acquired skills, similar deficits in patients with schizophrenia may reflect an altogether inadequately learned process.     

The production and understanding of utterances in dyadic communication

Verbal communication in four dyads was analyzed with respect to syntactic form and cognitive and affective functions. Quantitative and qualitative methods were proposed to study these aspects of language behaviour. Utterances which conveyed a negative affective evaluation tended to be syntactically and cognitively complex. The cognitive and affective functions of a speaker's utterance tended to influence the syntactic quality of the listener's following utterance more than what the listener said in his own previous utterance. An investigation of the relationships between the personality characteristics flexibility, intelligence and verbal competence, and language variables suggested that flexible subjects often used utterances which expressed a positive evaluation. Furthermore, flexible subjects tended to influence the listener more by what they said than intelligent and verbally competent subjects did. It was concluded that this kind of functional analysis of language should be more adequate for psychological inquiry than in particular that of the transformational generative theory of language.     

The treatment of borderline personalities with rational emotive behavior therapy

The rational emotive behavior therapy (REBT) theory holds that individuals with severe personality disorders in general, and borderline personalities in particular usually are biologically different from “normal” neurotics and are born with a predisposition to be highly vulnerable to stressful environmental conditions. They tend to have cognitive, emotional, and behavioral deficits or disabilities that handicap them socially, vocationally, and in other important aspects of their lives. But they also have distinct, and sometimes exceptionally strong, neurotic tendencies to demand that they absolutely must perform well, that other people have to treat them kindly and fairly, and that frustrating conditions ought not exist. Their neurosis exacerbates their cognitive-emotive-behavioral handicaps, produces even greater life difficulties, and often interferes with their working hard at therapy. A summary is presented of how borderline personalities can be treated with rational emotive behavior therapy (REBT).     

Uses of rational emotive behavior therapy with juvenile sex offenders

Juvenile sexual offenses appear to be on the rise. This contributes to harm and trauma to the victims and the community at large. For many years the major interest in sex offender treatment has been directed toward assessment and treatment of the adult offender in spite of the reported large proportion of all sex crimes committed by juveniles (Uniform Crime Reports, FBI, 1985). Our article addresses three uses of Rational-Emotive Behavior Therapy (REBT): 1) in group and individual therapy, 2) in work with the offender's family, and 3) in staff training. The issues of the client's faulty learning and cognitive distortions is critical in the habilitation and rehabilitation process and may include such messages as: 1) I am powerless to control my sexual arousal, 2) I won't get caught if I am careful, 3) Masturbating about little kids is OK, 4) I need to feel better and when I am sexual with someone I feel better. This article will describe how the theory and practice of REBT (Ellis' 1984) is applied with juvenile sex offenders. A key feature is its use with the offending juvenile in the teaching of a rational belief system as well as ways to reduce emotional disturbances.     

The practice of rational emotive and cognitive behavior therapy with offenders

The case for rational emotive behavior therapy (REBT) and cognitive behavior therapy (CBT) with offenders is reviewed. Philosophical and practical problems in conducting REBT assessment and treatment with this population are identified. Suggestions regarding offender treatment address goals and content of therapy, the therapeutic relationship, overcoming client resistance, and self-care for the practitioner. Therapists of offenders are encouraged to apply REBT to themselves to increase effectiveness and reduce risk. In this regard, clinicians are offered suggestions regarding accepting the offender, maintaining a goal-oriented focus, and taking responsibility for the quality but not the outcome of their work.     

Semantic sensitivity for prose in patients with probable alzheimer's disease

This study examined the sensitivity of patients with probable Alzheimer's Disease (AD) to the inherent semantic structure of prose. Patients and normal controls listened to prose passages and recalled the stories under immediate and delayed conditions. Subjects were also tested with a recognition format. Unlike controls and patients with mild AD, patients with severe AD were unable to differentiate high importance ideas from ideas of lower importance on free recall and recognition. These results suggest relative impairment of semantic processing at the encoding and consolidation process of memory in more advanced AD.     

Judgments about moral responsibility and determinism in patients with behavioural variant of frontotemporal dementia: still compatibilists

Do laypeople think that moral responsibility is compatible with determinism? Recently, philosophers and psychologists trying to answer this question have found contradictory results: while some experiments reveal people to have compatibilist intuitions, others suggest that people could in fact be incompatibilist. To account for this contradictory answers, Nichols and Knobe (2007) have advanced a ‘performance error model’ according to which people are genuine incompatibilist that are sometimes biased to give compatibilist answers by emotional reactions. To test for this hypothesis, we investigated intuitions about determinism and moral responsibility in patients suffering from behavioural frontotemporal dementia. Patients suffering from bvFTD have impoverished emotional reaction. Thus, the ‘performance error model’ should predict that bvFTD patients will give less compatibilist answers. However, we found that bvFTD patients give answers quite similar to subjects in control group and were mostly compatibilist. Thus, we conclude that the ‘performance error model’ should be abandoned in favour of other available model that best fit our data.     

Prognostic relevance of quantitative topographical EEG in patients with poststroke aphasia

In this prospective study we analyzed the prognostic value of topographical quantitative EEG (qEEG) in poststroke aphasia. Twenty-three right-handed patients (ages 56 +/- 12 years) with different types of aphasia were studied. Quantitative EEG under resting conditions and an aphasia test battery were applied twice, 2 and 8 weeks after a stroke. EEG power fast Fourier transform was performed for delta (2-3.5 Hz), theta (4-7.5 Hz), alpha (8-13 Hz), and beta (13.5-20 Hz) frequency bands. EEG abnormalities within and outside speech relevant areas are related to restitution of poststroke aphasia. In the ischemic regions they indicate local disturbances; outside they reflect failures in neuronal networks involved in the generation and propagation of the alpha rhythm.     

Semantic interference in language production is due to graded similarity,not response relevance

There is an ongoing debate on the question whether semantic interference effects in language production reflect competitive processes at the level of lexical selection or whether they reflect a post-lexical bottleneck, occupied in particular by response-relevant distractor words. To disentangle item-inherent categorical relatedness and task-related response relevance effects, we combined the picture–word interference task with the conditional naming paradigm in an orthogonal design, varying categorical relatedness and task-related response relevance independent of each other. Participants were instructed to name only objects that are typically seen in or on the water (e.g. canoe) and refrain from naming objects that are typically located outside the water (e.g. bike), and vice versa. Semantic relatedness and the response relevance of superimposed distractor words were manipulated orthogonally. The pattern of results revealed no evidence for response relevance as a major source of semantic interference effects in the PWI paradigm. In contrast, our data demonstrate that semantic similarity beyond categorical relations is critical for interference effects to be observed. Together, these findings provide support for the assumption that lexical selection is competitive and that semantic interference effects in the PWI paradigm reflect this competition.