On Broca, brain, and binding: a new framework

In speaking and comprehending language, word information is retrieved from memory and combined into larger units (unification). Unification operations take place in parallel at the semantic, syntactic and phonological levels of processing. This article proposes a new framework that connects psycholinguistic models to a neurobiological account of language. According to this proposal the left inferior frontal gyrus (LIFG) plays an important role in unification. Research in other domains of cognition indicates that left prefrontal cortex has the necessary neurobiological characteristics for its involvement in the unification for language. I offer here a psycholinguistic perspective on the nature of language unification and the role of LIFG.     

Implicit self-esteem: nature, measurement, and a new way forward

Gaining insight into the nature and consequences of people's global self-evaluations (i.e., their self-esteem) has been fraught with difficulty. Nearly 2 decades ago, researchers suggested that such difficulties might be addressed by the development of a new class of measures designed to uncover implicit self-esteem. In this article, we evaluate the construct validity of the 2 most common measures of implicit self-esteem, the Implicit Association Test (IAT) and Name-Letter Test (NLT). Our review indicates that the research literature has not provided strong or consistent support for the validity of either measure. We conclude that both tests are impoverished measures of self-esteem that are better understood as measures of either generalized implicit affect (IAT) or implicit egotism (NLT). However, we suggest that there surely are aspects of self-esteem that people are unwilling or unable to report and suggest a general approach that may allow researchers to tap these unspoken aspects of self-esteem.     

Rumination, reflection, intrusive thoughts, and hallucination-proneness: Towards a new model

Although rumination has been proposed to play an important role in the creation of hallucinations, direct empirical tests of this proposal have not yet been performed. Employing a distinction between ruminative and reflective self-consciousness, we set out to test a new model of the relations among rumination, reflection, intrusive thoughts, thought suppression, social anxiety, and hallucination-proneness. This model proposed that rumination would be related to hallucination-proneness through the mediating variable of intrusive thoughts, but that reflection would not be related to hallucination-proneness. The model was tested in a student population (N = 296) using path analyses. A modified version of the model was found to be a good fit to the data, once a direct path from reflection to hallucination-proneness had been added. As hypothesized, rumination was related to hallucination-proneness only indirectly, through the mediating variable of intrusive thoughts. Implications for interventions and future directions for research are considered.     

Human memory, cerebral hemispheres, and the limbic system: a new approach

An integrative approach to human memory is presented in the context of brain asymmetry. The results of psychophysiological investigations suggest that right-hemisphere functioning is closely associated with the limbic system; that association leads to the formation of a polysemantic context. Polysemantic context is determined by multiple interconnections among its elements; each element bears the stamp of the whole context. That context sustains episodic, personal, and emotionally laden memories. Left-hemisphere functioning leads to the formation of a monosemantic context, which is responsible for the maintenance of semantic memories. That distinction--in terms of general organization of material by hemispheres--explains such phenomena as memory disturbances among the very old, the influence of emotions on memory, and confabulations.     

Models of recognition, repetition priming, and fluency: exploring a new framework

We present a new modeling framework for recognition memory and repetition priming based on signal detection theory. We use this framework to specify and test the predictions of 4 models: (a) a single-system (SS) model, in which one continuous memory signal drives recognition and priming; (b) a multiple-systems-1 (MS1) model, in which completely independent memory signals (such as explicit and implicit memory) drive recognition and priming; (c) a multiple-systems-2 (MS2) model, in which there are also 2 memory signals, but some degree of dependence is allowed between these 2 signals (and this model subsumes the SS and MS1 models as special cases); and (d) a dual-process signal detection (DPSD1) model, 1 possible extension of a dual-process theory of recognition (Yonelinas, 1994) to priming, in which a signal detection model is augmented by an independent recollection process. The predictions of the models are tested in a continuous-identification-with-recognition paradigm in both normal adults (Experiments 1-3) and amnesic individuals (using data from Conroy, Hopkins, & Squire, 2005). The SS model predicted numerous results in advance. These were not predicted by the MS1 model, though could be accommodated by the more flexible MS2 model. Importantly, measures of overall model fit favored the SS model over the others. These results illustrate a new, formal approach to testing theories of explicit and implicit memory.     

Personality, stress and disease: description and validation of a new inventory

The construction of a new Personality-Stress Inventory is discussed, based on previous research and other types of inventory constructed on the same principles. Scores on the inventory divide people into six types, selectively prone to different types of disease. The instrument is administered twice, with six months intervening, and changes in the inventory scores are prognostic of the probability of contracting different diseases. Evidence is presented to show the validity of the questionnaire and the method used.     

Soul-making theodicy and compatibilism: new problems and a new interpretation

In the elaboration of his soul-making theodicy, John Hick agrees with a controversial point made by compatibilists Antony Flew and John Mackie against the free will defense. Namely, Hick grants that God could have created humans such that they would be free to sin but would, in fact, never do so. In this paper, I identify three previously unrecognized problems that arise from his initial concession to, and ultimate rejection of, compatibilism. The first problem stems from the fact that in two important texts, Hick rejects compatibilism (after having endorsed it as effective against the free will defense) for different and seemingly contradictory reasons. His various explanations of soul-making theodicy’s relationship to compatibilism are therefore in conflict. The second problem is closely related to the first. It turns out that when Hick’s concession to compatibilism is closely examined, soul-making theodicy appears unable to explain the existence of moral evil. The final problem consists in understanding why Hick would have made any concessions to compatibilism in the first place given that he ultimately opts for incompatibilist free will. After identifying these three problems, I develop a distinctive way in which to interpret Hick’s soul-making theodicy that solves the first two. This distinctive interpretation, moreover, has the added benefit of solving another, well-recognized problem that has long plagued Hick’s exposition: the problem of the hypnotist metaphor. Finally, I address the third problem by suggesting a rationale for Hick’s initial concession to the compatibilists.     

Linguistic and nonlinguistic impairments in writing: a comparison of patients with focal and multifocal CNS disorders

The hypothesis that the language disorder in Alzheimer's disease (AD) depends on degenerative brain changes in classical left-hemisphere language zones was tested by comparing the written language performances of a group of AD patients with mild-moderate dementia and left-hemisphere stroke patients with equally severe naming and auditory comprehension deficits who were in varying stages of recovery from Wernicke's aphasia. The results indicated significant qualitative group differences in performances between tasks and in errors within tasks. The findings are consistent with hypothesized disruption of more diffusely organized neurolinguistic systems in AD. The hypothesis that the language disorder in AD represents an exaggeration of the pattern of language change in normal aging was also examined by comparing the performances of AD patients to the changes that occur with very advanced normal aging. The data indicate convergence between AD and very elderly healthy subjects in some aspects of written language production.     

Children, adolescents, and the internet: a new field of inquiry in developmental psychology

With this special section on children, adolescents, and the Internet, we survey the state of a new field of inquiry in developmental psychology. This field is important because developmentalists need to understand how children and adolescents live in a new, massive, and complex virtual universe, even as they carry on their lives in the real world. We have selected six empirical articles to showcase various aspects of child and adolescent development in this virtual universe. These articles reflect three major themes of this new field: communication on the Internet; cognitive development, academic achievement, and the Internet; and adolescents in a globalized Internet world. These three sections reflect one of our major editorial goals: to sample various relevant aspects of development as they relate to the Internet. The selection of articles reflects a second editorial goal: to sample both the positive and negative aspects of the virtual world in which children and adolescents are increasingly living. Another of our editorial goals was to sample as large an age range as possible. We also utilized a very broad definition of development. Last but not least, we sought out and found methodological diversity.     

Coping through emotional approach: a new look at emotion, coping, and health-related outcomes

Researchers studying stress and coping processes have attempted to identify which coping strategies are most adaptive in stressful encounters. A generally accepted conclusion has been that emotion-focused coping processes are associated with dysfunctional outcomes. Studies from our and other research teams challenge the "bad reputation" of emotion-focused coping by demonstrating that items measuring emotion-focused strategies in published coping questionnaires are confounded with distress and self-deprecation. We have developed and validated new instruments to assess coping though acknowledging, understanding, and expressing emotion, that is, coping through emotional approach. Longitudinal and experimental studies using these new scales have documented the adaptive potential of emotional-approach coping in the context of several types of stressors, including infertility, breast cancer, and chronic pain. However, characteristics of the environmental context, stressful experience, and individual are important moderators of the relations of emotional-approach coping and health-related outcomes. Potential mediators and moderators of coping through emotional approach, clinical relevance of the construct, and directions for research are discussed.     

Working memory, text comprehension, and propositional reasoning: a new Semantic Anaphora WM test

The aim of this study was to present a new working memory test following the line of work started by García-Madruga et al. (2007) and to examine its relation to reading comprehension and propositional reasoning measures. In that study we designed a new working memory span test--based on Daneman & Carpenter's (1980) Reading Span Test (RST)--in which the processing task called for an inferential decision--to resolve a pronominal anaphora based on Morpho-Syntactic cues and had people recall the result of this inference. In the current study, besides the RST and the Morpho-Syntactic Anaphora test, we presented a new Semantic Anaphora measure. In order to check the validity of this new Working Memory (WM) task, we used the same reasoning task used in the previous study as well as a new reading comprehension test. The results show the tight relationship amongst working memory, reading comprehension and reasoning, and confirm the validity of the new WM measure.     

Blood glucose and brain function: interactions with CNS cholinergic systems

We recently found that glucose injections attenuate amnesia and hyperactivity produced by scopolamine, a muscarinic antagonist. The present study examined whether glucose would augment behavioral effects produced by a muscarinic agonist, physostigmine. In experiment I, doses were first determined for which neither glucose (10 mg/kg) nor physostigmine (0.05 mg/kg) altered scopolamine-induced hyperactivity. However, combined glucose-physostigmine injections significantly reduced scopolamine hyperactivity. Experiment II evaluated the effects of glucose on physostigmine-induced tremors. Glucose (10, 100, and 250 mg/kg) or saline injections were given 20 min before physostigmine injections (0.4 or 0.05 mg/kg). Observations of glucose effects on the severity of physostigmine-induced tremors were then obtained at 5-min intervals for 25 min after physostigmine injections. Glucose (100 mg/kg) significantly facilitated the onset of tremors when injected before either dose of physostigmine, and augmented (at 100 and 250 mg/kg) tremor severity when injected before the lower dose of physostigmine. These findings indicate that glucose can facilitate the actions of a cholinergic agonist on two behaviors, locomotor activity and tremors, adding support to the view that circulating glucose levels can modulate central cholinergic function. More generally, the results provide additional evidence that circulating glucose levels can influence brain function.     

Self-experimentation as a source of new ideas: ten examples about sleep, mood, health, and weight

Little is known about how to generate plausible new scientific ideas. So it is noteworthy that 12 years of self-experimentation led to the discovery of several surprising cause-effect relationships and suggested a new theory of weight control, an unusually high rate of new ideas. The cause-effect relationships were: (1) Seeing faces in the morning on television decreased mood in the evening (> 10 hrs later) and improved mood the next day (> 24 hrs later), yet had no detectable effect before that (0-10 hrs later). The effect was strongest if the faces were life-sized and at a conversational distance. Travel across time zones reduced the effect for a few weeks. (2) Standing 8 hours per day reduced early awakening and made sleep more restorative, even though more standing was associated with less sleep. (3) Morning light (1 hr/day) reduced early awakening and made sleep more restorative. (4) Breakfast increased early awakening. (5) Standing and morning light together eliminated colds (upper respiratory tract infections) for more than 5 years. (6) Drinking lots of water, eating low-glycemic-index foods, and eating sushi each caused a modest weight loss. (7) Drinking unflavored fructose water caused a large weight loss that has lasted more than 1 year. While losing weight, hunger was much less than usual. Unflavored sucrose water had a similar effect. The new theory of weight control, which helped discover this effect, assumes that flavors associated with calories raise the body-fat set point: The stronger the association, the greater the increase. Between meals the set point declines. Self-experimentation lasting months or years seems to be a good way to generate plausible new ideas.