药物临床试验伦理审查的跟踪审查程序研究

为了保护受试者的合法权益,药物临床试验的伦理审查必须规范化进行.通过走访哈尔滨医科大学附属医院伦理委员会了解到,伦理审查程序缺乏相对完整性,特别是跟踪审查程序还在完善过程中,没有形成统一具体的操作规程.对此,结合我国实际情况,借鉴国外先进经验,提出构建药物临床试验跟踪审查程序的建议.     

A Paradigm Shift in the Implementation of Ethics Codes in Construction Organizations in Hong Kong: Towards an Ethical Behaviour

Science and Engineering Ethics - Due to the economic globalization which is characterized with business scandals, scholars and practitioners are increasingly engaged with the implementation of...     

支持死后医疗数据捐赠：呼吁对个人健康数据的伦理利用

死后医疗数据捐赠对于科学研究的意义重大。但目前不存在有针对性的准则用于指导捐赠过程。如果死后医疗数据的使用缺乏监管可能会引发多种风险,一是给他人利益造成损害;二是造成数据的不规范使用。因此,应当类比现有捐献制度,允许并鼓励捐献死后医疗数据用于科学研究,并起草专门的捐赠准则。该准则的制定应当建立在遵循五大基本原则的前提下,主张以自愿参与的方式使用个人医疗数据,反对未经书面同意将数据用于以病例档案为基础的医学研究。

     

CRM in Sales-Intensive Organizations: A Review and Future Directions

With the advent of technology enabling greater customer tracking, more robust knowledge management, and direct customer communication, the implementation of customer relationship management (CRM) strategies has grown in importance with many implications for sales-intensive organizations. Implications of CRM strategy, analytical CRM, and operational CRM are discussed, particularly in terms of research opportunities. Although there are, no doubt, many other interesting and worthwhile research opportunities available, the nexus of technology, CRM, and sales-intensive go-tomarket strategies provide myriad opportunities for exciting research.     

Gender Differences in Impression Management in Organizations: A Qualitative Review

In this article we review the literature on impression management to determine if there are substantial gender differences in the employment of impression management tactics in organizational contexts. Based on a social roles theory perspective (Eagly, 1987), we examined use of impression management tactics in organizational settings for gender differences in behavior. We expected that men and women would generally report using impression management tactics consistent with gender role expectations and that this might not be advantageous to women in the corporate world. Our review of the literature supported our expectations. We conclude with implications of these findings for an enriched understanding of organizational behavior.     

世界和谐:全球治理中国际组织的伦理诉求

世界和平与发展需要和谐的国际社会环境,世界和谐是构建性的。以世界和谐为伦理诉求的国际组织在全球治理中发挥着重要的作用,并遵循公正与共生的伦理原则。同时,在实践中正确处理有关主权、人权、国际责任、人道主义等方面的问题,才能真正实现世界和谐。     

生物医药研究伦理审查的体制机制建设

生物医药研究伦理审查在项目设计、论证和科学研究过程的审查,以及伦理委员会特别是伦理审查的评价方面较薄弱.要提高伦理审查的整体水平,需实现道德建设与法治建设、各级各类规定、科技监管与伦理监管的密切配合;伦理审查应始自科研设计、立项,强化跟踪审查,加强对伦理委员会工作的检查、评估,进而提高伦理审查能力培训的实际效果.     

A Systematic Review and Quality Assessment of Therapeutic Group Process Questionnaires

ABSTRACT

The aims of this study were to systematically review the literature on questionnaire-based group process measures and assess the psychometric scale development properties of these measures. A systematic search of questionnaire-based measures of group process was conducted from four databases: PsycINFO, Medline, EMBASE and AMED. A quality assessment was undertaken using established criteria. Only studies that described the development of questionnaire-based scales were included. Seventeen studies which described thirteen measures were included in the analysis. The developed list highlights a range of questionnaires that can be used by clinicians and researchers seeking to measure either “specific therapeutic group mechanisms” or “overall group experiences.” Further research should focus on developing the content validity of these scales by involving the target population during item selection and reduction.     

基于共济方法的研究型生物样本库伦理治理框架评析

基于共济的伦理治理框架符合研究型生物样本库的核心价值和目标、承认人们积极参与的意愿、减少研究成本和参与者伤害、加速推进研究型生物样本库的建设等,避免了基于自主权的风险治理框架的缺陷。但该框架不适用于商业型生物样本库、过分强调节约研究成本、减少伤害而忽视了研究过程中的风险预防以及缺少相应的伦理规范和外部监督。建议在选择共济框架时充分考虑大数据背景下研究中的不确定性和复杂性风险,重视对参与者个体自主权和风险的考量,探求与基于自主权的风险治理框架的互补与融合,并加强公众参与和外部监督。

     

Energy Management of People in Organizations: A Review and Research Agenda

Although energy is a concept that is implied in many motivational theories, is hardly ever explicitly mentioned or researched. The current article first relates theories and research findings that were thus far not explicitly related to energy. We describe theories such as flow, subjective well-being, engagement and burn-out, and make the link with energy more explicit. Also, we make a first link between personality characteristics and energy, and describe the role of leadership in unleashing followers’ energy. Following, we identify how the topic of energy management can be profitably incorporated in research from a scientific as well as a practitioner viewpoint. Finally, we describe several interventions to enhance energy in individuals and organizations.     

组织情境中的影响策略研究述评

影响策略是指个体采取的旨在使他人态度和行为产生预期改变的行为方式。组织情境下的影响策略受动机、场控制和自我监控等因素的影响,对工作绩效、薪酬、晋升和一些积极组织行为有显著的预测作用。本文侧重介绍了影响策略的结构、测量、前因后果变量以及跨文化研究等方面内容,总结了已有研究为管理实践提供的有价值参考,并指出研究方法的有效互补、对基层职员影响策略的关注和基于中国人行为观念的本土化研究是今后探讨的主要方向。     

Self-directedness: A Process Approach to Cognition

Standard approaches to cognition emphasise structures (representations and rules) much more than processes, in part because this appears to be necessary to capture the normative features of cognition. However the resultant models are inflexible and face the problem of computational intractability. I argue that the ability of real world cognition to cope with complexity results from deep and subtle coupling between cognitive and non-cognitive processes. In order to capture this, theories of cognition must shift from a structural rule-defined conception of cognition to a thoroughgoing embedded process approach.     

The Consulting Process: A Multidimensional Approach

The consulting process seems to work similarly regardless of whether the consultant is internal or external or is doing individual or group consultation. Some differences may occur depending on whether the consultant is a process helper or content helper, although good content-focused consultants often possess excellent process skills and use them as a regular part of the consulting process. Several consultation processes were reviewed, and from this a six-step approach is presented.     

Assessment of the Content and Process of Genetic Counseling: A Critical Review of Empirical Studies

This article reviews studies that assessed the process and content of genetic counseling communication. A systematic search of the literature was undertaken of studies that audio- or videotaped genetic counseling sessions conducted by genetics health care providers and subjected them to communication analyses. A total of 18 studies (published in 34 articles) were identified that met the eligibility criteria. Studies show that providers speak more than clients, that a large proportion of communication is biomedical rather than psychosocial and that the teaching model of genetic counseling is widely implemented. Higher levels of counselor facilitation of understanding and empathic responses, lower levels of verbal dominance (ratio of counselor to client talk) and the provision of a summary letter of the consultation are associated with more positive client outcomes. Findings from these studies should be used as an evidence base for teaching and continuing education of genetic counseling providers.     

Employing Ethical Codes and Decision-Making Models: A Developmental Process

Counselors often encounter seemingly intractable ethical dilemmas. To assist counselors who face difficult situations, the helping professions have generated both ethical codes and decision-making models. Because the process of decision making seems to be related to cognitive-moral development, this article details ethical codes and decision models and speculates on how counselor level of development may influence use of such codes and models.     

Ethical Codes in Sports Organizations: An Empirical Study on Determinants of Effectiveness

Confronted with numerous scandals, sports organizations are turning to the adoption of ethical codes to attain more ethical behavior. However, the effectiveness of an ethical code as a means to increase ethical behavior remains debated; furthermore, the particular characteristics of a sports context have not yet been taken into account, nor have the different stages of code establishment been considered in evaluation. This article studies the effectiveness, as measured by the Ethical Climate Index, of ethical codes in sports organizations. Moreover, it investigates the effects of the presence, creation, content, implementation, and enforcement of ethical codes on ethical behavior in sports organizations. Our results shed a light on the conditions that need to be in place to install an effective ethical code in sports organizations: a genuine motivation to improve ethical behavior, the involvement of coaches, and the explicit targeting of the management.     

Ethical Challenges with Welfare Technology: A Review of the Literature

Demographical changes in high income counties will increase the need of health care services but reduce the number of people to provide them. Welfare technology is launched as an important measure to meet this challenge. As with all types of technologies we must explore its ethical challenges. A literature review reveals that welfare technology is a generic term for a heterogeneous group of technologies and there are few studies documenting their efficacy, effectiveness and efficiency. Many kinds of welfare technology break with the traditional organization of health care. It introduces technology in new areas, such as in private homes, and it provides new functions, e.g. offering social stimuli and entertainment. At the same time welfare technology is developed for groups that traditionally have not been extensive technology users. This raises a series of ethical questions with regard to the development and use of welfare technologies, which are presented in this review. The main challenges identified are: (1) Alienation when advanced technology is used at home, (2) conflicting goals, as welfare technologies have many stakeholders with several ends, (3) respecting confidentiality and privacy when third-party actors are involved, (4) guaranteeing equal access and just distribution, and (5) handling conflicts between instrumental rationality and care in terms of respecting dignity and vulnerability. Addressing these issues is important for developing and implementing welfare technologies in a morally acceptable manner.     

Conceptualizing and Estimating Process Speed in Studies Employing Ecological Momentary Assessment Designs: A Multilevel Variance Decomposition Approach

Researchers have been making use of ecological momentary assessment (EMA) and other study designs that sample feelings and behaviors in real time and in naturalistic settings to study temporal dynamics and contextual factors of a wide variety of psychological, physiological, and behavioral processes. As EMA designs become more widespread, questions are arising about the frequency of data sampling, with direct implications for participants' burden and researchers' ability to capture and study dynamic processes. Traditionally, spectral analytic techniques are used for time series data to identify process speed. However, the nature of EMA data, often collected with fewer than 100 measurements per person, sampled at randomly spaced intervals, and replete with planned and unplanned missingness, precludes application of traditional spectral analytic techniques. Building on principles of variance partitioning used in the generalizability theory of measurement and spectral analysis, we illustrate the utility of multilevel variance decompositions for isolating process speed in EMA-type data. Simulation and empirical data from a smoking-cessation study are used to demonstrate the method and to evaluate the process speed of smoking urges and quitting self-efficacy. Results of the multilevel variance decomposition approach can inform process-oriented theory and future EMA study designs.     

Conceptualizing and Estimating Process Speed in Studies Employing Ecological Momentary Assessment Designs: A Multilevel Variance Decomposition Approach

Researchers have been making use of ecological momentary assessment (EMA) and other study designs that sample feelings and behaviors in real time and in naturalistic settings to study temporal dynamics and contextual factors of a wide variety of psychological, physiological, and behavioral processes. As EMA designs become more widespread, questions are arising about the frequency of data sampling, with direct implications for participants' burden and researchers' ability to capture and study dynamic processes. Traditionally, spectral analytic techniques are used for time series data to identify process speed. However, the nature of EMA data, often collected with fewer than 100 measurements per person, sampled at randomly spaced intervals, and replete with planned and unplanned missingness, precludes application of traditional spectral analytic techniques. Building on principles of variance partitioning used in the generalizability theory of measurement and spectral analysis, we illustrate the utility of multilevel variance decompositions for isolating process speed in EMA-type data. Simulation and empirical data from a smoking-cessation study are used to demonstrate the method and to evaluate the process speed of smoking urges and quitting self-efficacy. Results of the multilevel variance decomposition approach can inform process-oriented theory and future EMA study designs.