Social transmission of Pavlovian fear: fear-conditioning by-proxy in related female rats

Pairing a previously neutral conditioned stimulus (CS; e.g., a tone) to an aversive unconditioned stimulus (US; e.g., a foot-shock) leads to associative learning such that the tone alone will elicit a conditioned response (e.g., freezing). Individuals can also acquire fear from a social context, such as through observing the fear expression of a conspecific. In the current study, we examined the influence of kinship/familiarity on social transmission of fear in female rats. Rats were housed in triads with either sisters or non-related females. One rat from each cage was fear conditioned to a tone CS+ shock US. On day two, the conditioned rat was returned to the chamber accompanied by one of her cage mates. Both rats were allowed to behave freely, while the tone was played in the absence of the foot-shock. The previously untrained rat is referred to as the fear-conditioned by-proxy (FCbP) animal, as she would freeze based on observations of her cage-mate’s response rather than due to direct personal experience with the foot-shock. The third rat served as a cage-mate control. The third day, long-term memory tests to the CS were performed. Consistent with our previous application of this paradigm in male rats (Bruchey et al. in Behav Brain Res 214(1):80–84, 2010), our results revealed that social interactions between the fear conditioned and FCbP rats on day two contribute to freezing displayed by the FCbP rats on day three. In this experiment, prosocial behavior occurring at the termination of the cue on day two was significantly greater between sisters than their non-sister counterparts, and this behavior resulted in increased freezing on day three. Our results suggest that familiarity and/or kinship influences the social transmission of fear in female rats.     

Flushing propensity predicts fear of blushing

Motivation and Emotion - The aim of this study was to investigate the association between fear of blushing and self-rated propensity to flush to physical stimuli. Two hundred and five respondents...     

Dominance and social information use in a lizard

There is mounting evidence that social learning is not just restricted to group-living animals, but also occurs in species with a wide range of social systems. However, we still have a poor understanding of the factors driving individual differences in social information use. We investigated the effects of relative dominance on social information use in the eastern water skink (Eulamprus quoyii), a species with age-dependent social learning. We used staged contests to establish dominant–subordinate relationships in pairs of lizards and tested whether observers use social information to more quickly solve both an association and reversal learning task in situations where the demonstrator was either dominant or subordinate. Surprisingly, we found no evidence of social information use, irrespective of relative dominance between observer and demonstrator. However, dominant lizards learnt at a faster rate than subordinate lizards in the associative learning task, although there were no significant differences in the reversal task. In light of previous work in this species, we suggest that age may be a more important driver of social information use because demonstrators and observers in our study were closely size-matched and were likely to be of similar age.     

Infant social attention predicts preschool social cognition

Recent research examining infants' understanding of intentional action claims to be studying the early origins or precursors of children's later theories of mind If these infant understandings are continuous with later preschool achievements, there should be empirical connections between the two. We provide initial evidence that infants' social attention predicts later social cognition. Specifically, 14-month-olds' habituation to human intentional action significantly predicts later preschool mentalistic construal of persons, as measured on a Theory of Mind Scale.     

Non-specific effect of fear conditioning and specific effect of social defeat on social recognition memory performance in female rats

The so called "emotion learning" literature describes the ability of distressing and aversive unconditioned stimuli to classically condition a learned avoidance response. In order to investigate the impact of experience with noxious stimuli in one conditioning context on learning and memory performance in a separate, non-aversively motivated task, juvenile recognition ability was examined in adult female rats exposed previously to one of two environmental stressors. In particular, experimental adult rats were either socially defeated by exposure to an aggressive conspecific rat or fear conditioned using single or multiple pairings with footshock prior to performance of the social recognition task. Experiment 1 established that repeated exposure to a single juvenile resulted in social memory formation reflected in decreased social investigation from the first to the second exposure. Experiment 2 documented that both single and multiple pairings of an environment with footshock produced robust freezing behavior (90-95% suppression of activity). In addition, fear conditioning produced a non-specific 5-60% increase in social investigation time in both single and multiple-pairing fear conditioned groups which confounded the ability of the social recognition measure to assess effects of fear conditioning on learning and memory performance per se. In contrast, Experiment 3 documented that when social recognition memory performance was impaired to 85% of control levels by imposition of a 2 h delay, exposure to a social defeat stressor reinstated optimal social recognition memory performance. These findings suggest that the after effects of fear conditioning include non-specific alteration of social investigation whereas exposure to conspecific aggression enhances subsequent social recognition memory.     

Big-Five personality prospectively predicts Social Dominance Orientation and Right-Wing Authoritarianism

A full cross-lagged panel design examined the bidirectional effects of the Big-Five personality dimensions on Social Dominance Orientation (SDO) and Right-Wing Authoritarianism (RWA) over 9 months (N = 190 undergraduates). Consistent with the Dual Process Cognitive-Motivational Model, SDO and RWA exhibited markedly different personality bases. Low Agreeableness predicted change in the motivational goal for group-based dominance and superiority (SDO), whereas Openness to Experience predicted change in the motivational goal for social cohesion and collective security (RWA). Extending previous longitudinal research, this study indicates that the effect of personality on ideology is unidirectional, as RWA and SDO did not predict reciprocal prospective change in broad-bandwidth personality. These findings are consistent with a model in which relatively stable broad-bandwidth personality traits shape ideological attitudes over even relatively short time periods, and not the reverse.     

Reciprocal inhibition of a laboratory conditioned fear

Electric shock was used to establish a conditioned fear in 48 college Ss, who then received either deep muscle relaxation training, cognitive relaxation training or anxiety relief conditioning. Relaxation was conditioned to a slide of the word NOW and the aversive stimulus was a pure red slide. The compound stimulus NOW on a red background was presented to generate counterconditioning, followed by a re-presentation of pure red as a measure of transfer. GSR and Blood Volume Pulse were recorded for evaluation of the fear reduction generated by each training procedure. All group differences were non-significant. The two relaxation procedures were equally effective, while the Anxiety Relief group manifested consistently smaller response-reduction. Implications and the usefulness of the paradigm were discussed.     

Accurate identification of fear facial expressions predicts prosocial behavior

The fear facial expression is a distress cue that is associated with the provision of help and prosocial behavior. Prior psychiatric studies have found deficits in the recognition of this expression by individuals with antisocial tendencies. However, no prior study has shown accuracy for recognition of fear to predict actual prosocial or antisocial behavior in an experimental setting. In 3 studies, the authors tested the prediction that individuals who recognize fear more accurately will behave more prosocially. In Study 1, participants who identified fear more accurately also donated more money and time to a victim in a classic altruism paradigm. In Studies 2 and 3, participants' ability to identify the fear expression predicted prosocial behavior in a novel task designed to control for confounding variables. In Study 3, accuracy for recognizing fear proved a better predictor of prosocial behavior than gender, mood, or scores on an empathy scale.     

Conflict,fear and social identity in Nagaland

This survey study tested the effects of exposure to ethnopolitical conflict and violence and social group identification on psychosocial well‐being among a sample of Nagas (n = 280). Nagaland is located in Northeast India, and for decades has suffered from armed conflict and political instability. It was predicted that reported exposure to conflict would be positively associated with reported levels of fear, which in turn would decrease psychosocial well‐being (assessed with the indices life satisfaction, self‐esteem and general health). It was also expected that strongly identifying with being Naga would be positively related to perceived levels of social support, which in turn were predicted to be positively related to well‐being. Last but not least, it was hypothesized that conflict and fear would also directly and negatively impact on levels of identification with being Naga: increased conflict‐induced fear was expected to reduce the strength of the group identification. These predictions were confirmed by structural equation modelling.     

The intergenerational transmission of fear of failure

The intergenerational transmission of fear of failure was examined in two studies with undergraduates and their parents. Parent-undergraduate concordance in fear of failure was documented for mothers and fathers, controlling for parents' and undergraduate's impression management and self-deceptive enhancement response tendencies. Love withdrawal was validated as a mediator of parent-undergraduate concordance in fear of failure for mothers but not for fathers. Mothers' and fathers' fear of failure was also a positive predictor of undergraduate's adoption of performance-avoidance goals in the classroom, and undergraduate's fear of failure was shown to mediate this relationship. Fathers' fear of failure was also a negative predictor of undergraduate's mastery goal adoption, and this relationship was likewise mediated by undergraduate's fear of failure. The results are discussed in terms of the reorienting of positive, appetitive achievement motivation toward negative, aversive achievement motivation.     

Gender dimorphic effects of voluntary running in laboratory rats depends on maturational status

This study examined the effect of 24 hr per day wheel access on running, body weight, and food intake for 30- or 50-day-old male and female rats under ad lib feeding conditions. Food intake and body weight were also monitored in a control group housed without access to running wheels. A dimorphic effect was observed after wheel introduction in 50-day-old but not 30-day-old rats: A temporary decline in food intake and a lasting decrease in body weight occurred for active male rats in comparison to their sedentary controls, and wheel access facilitated food intake and preserved body weight gain in female rats in comparison to their sedentary counterparts. Hyperphagia in adult females is interpreted in terms of the evolutionary acquired advantage linked to their reproductive function.     

Gender dimorphic effects of voluntary running in laboratory rats depends on maturational status

This study examined the effect of 24?hr per day wheel access on running, body weight, and food intake for 30- or 50-day-old male and female rats under ad lib feeding conditions. Food intake and body weight were also monitored in a control group housed without access to running wheels. A dimorphic effect was observed after wheel introduction in 50-day-old but not 30-day-old rats: A temporary decline in food intake and a lasting decrease in body weight occurred for active male rats in comparison to their sedentary controls, and wheel access facilitated food intake and preserved body weight gain in female rats in comparison to their sedentary counterparts. Hyperphagia in adult females is interpreted in terms of the evolutionary acquired advantage linked to their reproductive function.     

Adrenergic transmission facilitates extinction of conditional fear in mice

Extinction of classically conditioned fear, like its acquisition, is active learning, but little is known about its molecular mechanisms. We recently reported that temporal massing of conditional stimulus (CS) presentations improves extinction memory acquisition, and suggested that temporal spacing was less effective because individual CS exposures trigger two opposing processes: (1) fear extinction, which is favored by CS massing, and (2) fear incubation (increase), which is favored by spacing. We here report the effects of manipulating the adrenergic system during massed or spaced CS presentations in fear-conditioned mice. We administered yohimbine (5 mg/kg), an alpha(2)-receptor antagonist, or propranolol (10 mg/kg), a beta-receptor antagonist, systemically prior to CS presentation sessions and recorded both short- and long-term changes in conditional freezing. Yohimbine treatment facilitated extinction of both cue and context fear with massed protocols. When given before spaced CS presentations, propranolol led to a persistent incubation of cue fear, whereas yohimbine led to persistent extinction, compared with vehicle-treated animals, which showed no change in fear. These results suggest that norepinephrine positively modulates the formation of fear extinction memories in mice. They also provide clear evidence that spaced CS presentations trigger both fear-reducing (extinction) and fear-increasing (incubation) mechanisms.     

Contextual fear conditioning predicts subsequent avoidance behaviour in a virtual reality environment

Avoidance behaviour is a crucial component of fear and is importantly involved in the maintenance of anxiety disorders. Presumably, fear conditioning leads to avoidance of the feared object or context. A virtual reality contextual fear conditioning paradigm was used to investigate the association between explicit conditioning effects and subsequent avoidance behaviour. Mild electric shocks were administered in one context (anxiety context), but never in a second context (safety context). Subsequent avoidance behaviour was assessed by asking participants to choose two out of three contexts (a neutral context was added) to visit again. Participants avoided the anxiety context, but did not prefer the safety over the neutral context. Participants with substantial conditioning effects, as reflected in differential valence, arousal and anxiety ratings, avoided the anxiety context but not the safety context. In sum, we demonstrated an association between context conditioning effects on an explicit level and later avoidance behaviour.     

Contextual fear conditioning predicts subsequent avoidance behaviour in a virtual reality environment

Avoidance behaviour is a crucial component of fear and is importantly involved in the maintenance of anxiety disorders. Presumably, fear conditioning leads to avoidance of the feared object or context. A virtual reality contextual fear conditioning paradigm was used to investigate the association between explicit conditioning effects and subsequent avoidance behaviour. Mild electric shocks were administered in one context (anxiety context), but never in a second context (safety context). Subsequent avoidance behaviour was assessed by asking participants to choose two out of three contexts (a neutral context was added) to visit again. Participants avoided the anxiety context, but did not prefer the safety over the neutral context. Participants with substantial conditioning effects, as reflected in differential valence, arousal and anxiety ratings, avoided the anxiety context but not the safety context. In sum, we demonstrated an association between context conditioning effects on an explicit level and later avoidance behaviour.     

Effects of reactivity to dorsal stimulation and social role on aggressive behavior in laboratory rats

Rats were selected on the basis of reactivity to dorsal tactile stimulation and then tested in a resident-intruder paradigm. While reactivity of residents did not influence the occurrence of agonistic behaviors or wounding of residents and intruders, reactivity of intruders did affect offensive and defensive patterns of interactions and the wounds sustained by residents and intruders. Subsequent to resident-intruder testing, rats were tested for shock-induced aggression. The pattern of the results and the results of additional experiments demonstrated that resident-intruder experience could affect subsequent shock-induced aggressive behavior.     

Learning to avoid spiders: fear predicts performance,not competence

We used an immersive virtual environment to examine avoidance learning in spider-fearful participants. In 3 experiments, participants were asked to repeatedly lift one of 3 virtual boxes, under which either a toy car or a spider appeared and then approached the participant. Participants were not told that the probability of encountering a spider differed across boxes. When the difference was large (Exps. 1 and 2), spider-fearfuls learned to avoid spiders by lifting the few-spiders-box more often and the many-spiders-box less often than non-fearful controls did. However, they hardly managed to do so when the probability differences were small (Exp. 3), and they did not escape from threat more quickly (Exp. 2). In contrast to the observed performance differences, spider-fearfuls and non-fearfuls showed equal competence, that is comparable post-experimental knowledge about the probability to encounter spiders under the 3 boxes. The limitations and implications of the present study are discussed.     

Social fear and expressive reactions to social stimuli

This study explored whether subjects high as compared to low in social fear react with a more negative emotional response, measured as facial electromyographic (EMG) activity, when exposed to social stimuli (pictures of angry and happy facial expressions). It was found that subjects who rated themselves as relatively high in public speaking fear gave larger negative facial EMG responses (Corrugator supercilii muscle activity) to angry faces than did the low fear subjects. Low fear subjects, on the other hand, gave larger positive facial EMG responses (Zygomatic major muscle activity) to happy faces than did the high fear subjects. It was further found that happy stimuli were rated as more hostile and less friendly and happy by the high fear group. Consistent with earlier findings, it was concluded that the facial EMG technique is sensitive to detecting different reactions among subjects relatively high and low in social fear.