Selective delayed alternation deficits in dominantly inherited olivopontocerebellar atrophy

In order to characterize more completely the nature of the frontal lobe-type cognitive changes in patients with dominantly inherited olivopontocerebellar atrophy (OPCA) we administered two tasks sensitive to frontal system dysfunction, delayed alternation (DA) and delayed response (DR), to 12 patients from one OPCA family. Affected members from this family have previously been shown to have a marked and widespread cerebral (including frontal) cortical cholinergic reduction as severe as that observed in Alzheimer's disease. Performance on DA, but not on DR, was significantly impaired in the OPCA patients compared to that in the controls. We suggest that the DA deficits in OPCA could be a consequence of a loss of cholinergic innervation to orbitofrontal or possibly temporal cortical areas and/or damage to the integrity of the cerebello-frontal neuronal connections.     

Adapting to the surface: A comparison of handwriting measures when writing on a tablet computer and on paper

Our study addresses the following research questions: Are there differences between handwriting movements on paper and on a tablet computer? Can experienced writers, such as most adults, adapt their graphomotor execution during writing to a rather unfamiliar surface for instance a tablet computer?We examined the handwriting performance of adults in three tasks with different complexity: (a) graphomotor abilities, (b) visuomotor abilities and (c) handwriting. Each participant performed each task twice, once on paper and once on a tablet computer with a pen.We tested 25 participants by measuring their writing duration, in air time, number of pen lifts, writing velocity and number of inversions in velocity. The data were analyzed using linear mixed-effects modeling with repeated measures.Our results reveal differences between writing on paper and on a tablet computer which were partly task-dependent. Our findings also show that participants were able to adapt their graphomotor execution to the smoother surface of the tablet computer during the tasks.     

空间书写障碍的个案研究

根据书写加工理论,从异形字水平、图解动作模式水平和神经动作执行水平三个方面,综合考察一例空间书写障碍儿童的认知加工特点。结果表明：（1）个案QY的异形字水平出现选择性损伤,在视觉整体特征的知觉加工上存在困难,导致自发书写的汉字难以辨识,存在严重的间架结构问题。（2）个案QY在图解动作模式水平以及神经动作执行水平上表现正常     

Eye movements during the handwriting of words: Individually and within sentences

Handwriting, a complex motor process involves the coordination of both the upper limb and visual system. The gaze behavior that occurs during the handwriting process is an area that has been little studied. This study investigated the eye-movements of adults during writing and reading tasks. Eye and handwriting movements were recorded for six different words over three different tasks. The results compared reading and handwriting the same words, a between condition comparison and a comparison between the two handwriting tasks. Compared to reading, participants produced more fixations during handwriting tasks and the average fixation durations were longer. When reading fixations were found to be mostly around the center of word, whereas fixations when writing appear to be made for each letter in a written word and were located around the base of letters and flowed in a left to right direction. Between the two writing tasks more fixations were made when words were written individually compared to within sentences, yet fixation durations were no different. Correlation of the number of fixations made to kinematic variables revealed that horizontal size and road length held a strong correlation with the number of fixations made by participants.     

Reading and Writing Motivation of Third to Sixth Graders

Motivational questionnaires (MRP-R and MWP) were used to investigate reading and writing motivation (self-concept and value) among 252 Hebrew-speaking students in third to sixth grade. CFA for reading and writing motivation revealed a close to reasonable fit, for the total sample and by gender. It yielded a low fit across the four grade levels. Four main results were obtained: (1) reading and writing motivation remained at the same level in all four grades; (2) reading motivation was higher than writing motivation; (3) students’ self-concept was higher than value in both reading and writing; (4) value of reading was higher than value of writing. It is suggested that educators take into account the importance of increasing reading and writing motivation in the early years of elementary school, before motivation stabilizes in third grade. Additionally, attention should be paid to the value that students attach to reading and especially writing, since it may be related to their involvement in reading and writing tasks. Further examination and development of the questionnaire assessing writing motivation is required. More implications of the results for developmental aspects of reading and writing motivation are discussed.     

Writing,Reading, and Listening Differentially Overload Working Memory Performance Across the Serial Position Curve

Previous research has assumed that writing is a cognitively complex task, but has not determined if writing overloads Working Memory more than reading and listening. To investigate this, participants completed three recall tasks. These were reading lists of words before recalling them, hearing lists of words before recalling them, and hearing lists of words and writing them as they heard them, then recalling them. The experiment involved serial recall of lists of 6 words. The hypothesis that fewer words would be recalled overall when writing was supported. Post-hoc analysis revealed the same pattern of results at individual serial positions (1 to 3). However, there was no difference between the three conditions at serial position 4, or between listening and writing at positions 5 and 6 which were both greater than recall in the reading condition. This suggests writing overloads working memory more than reading and listening, particularly in the early serial positions. The results show that writing interferes with working memory processes and so is not recommended when the goal is to immediately recall information.     

SPELLING AND THE GROWTH OF CONCEPT OF WORD AS FIRST GRADERS WRITE

Word is a critical concept in beginning literacy, a foundation for both reading and orthographic understanding. In this study, the development of concept of word in children's own writing during first grade was examined and its relationship with developing spelling ability was described.

Children in three intact first grade classes were assigned concept of word tasks "typical" of first grade instruction at the beginning and end of the year. The spaces left between words as the children copied from the board, wrote from dictation, and created their own stories in a free writing task were counted and compared across tasks and between Fall and Spring. In addition, the children were given an assessment of their developmental spelling level at both times. The spelling scores were compared with the concept of word measures.

Analyses of the Fall data revealed that the word concept tasks were significantly related to each other, suggesting that the tasks tap different aspects of the same construct, concept of word. Spelling development was also related to concept of word, and children who demonstrated use of a letter name strategy in spelling were more likely to perform well on the concept of word tasks.

A 3 (word concept tasks) x 2 (trials) MANOVA identified a significant interaction between tasks and trials. Post hoc analyses found significant differences among all of the concept of word tasks overall. In the Fall, all comparisons among the tasks were significant, and in the Spring, all except the difference between Copied and Dictated were significant.

There appears to be a developmental hierarchy in acquisition of concept of word which is related to the perceptual demands of writing tasks. Though important gains in conceptual understanding are made during the first grade year, there are still differences in performance on concept of word tasks at the end of first grade.     

An analysis of writing in a case of deep dyslexia

In tests of her ability to produce written and spoken language, this deep dyslexic patient produced semantic, visual, and derivational errors, including functor substitutions, and exhibited part-of-speech and abstractness effects in oral reading, oral and written naming, and writing to dictation, but not in repetition of single words and copying from memory. This patient therefore provides confirmation of the hypothesis presented in Nolan and Caramazza (1982) that the defining symptoms of deep dyslexia will be observed in responses to any task which requires lexical mediation. The patient's written responses in all tasks but direct copying were characterized by spelling errors which included transpositions, omissions, substitutions, and additions of letters. A model of writing is proposed which explains these errors in terms of a disruption of a phoneme-grapheme conversion process which normally functions to prevent decay of information from a Graphemic Buffer.     

Phonological deficits: Beneath the surface of reading-acquisition problems

Summary In Experiment 1, the performance of young retarded readers on speech-segmentation tasks was compared with the performance of normal subjects matched for chronological age (CA) and with subjects matched for reading age (RA). Retarded readers were poorer than both control groups in consonant deletion, while there was no difference between the groups on a rhyme-judgement task and a syllabic-vowel-reproduction task. In Experiment 2, another group of reading retarded children was compared with CA and RA controls on the classification of pseudowords, either by common phoneme or by overall phonetic similarity. The retarded readers made fewer classifications based on common phoneme than both control groups, while there was no difference between the groups in classifications based on overall phonetic similarity. In Experiment 3, adult developmental dyslexics were compared with normal adults in the tasks of Experiments 1 and 2. The dyslexics made fewer classifications based on a common phoneme than the normals, while no difference was found in classifications based on overall phonetic similarity.     

Mental representation of prepositional compounds: evidence from Italian agrammatic patients

The processing of Prepositional compounds (typical Neo-latin noun--noun modifications where a head noun is modified by a prepositional phrase, e.g., mulino a vento, windmill) was preliminarily studied with a group of six agrammatic aphasic patients, and, in more detail, with a further agrammatic patient (MB). Omission was the most frequent error type in naming, whereas in the other tasks (repetition, reading, writing, and completion) errors were mostly substitutions of the target preposition. This happened even with fully lexicalized compound forms, i.e., those forms where the linking preposition is syntactically and semantically opaque. These findings are interpreted in terms of a dual-route theory of lexical access to morphologically complex words.     

Brain dopamine and kinematics of graphomotor functions

Three experiments were performed in an attempt to achieve a better understanding of the effect of dopamine on handwriting. In the first experiment, kinematic aspects of handwriting movements were compared between healthy participants and patients with Parkinson's disease (PD) on their usual dopaminergic treatment and following withdrawal of dopaminergic medication. In the second experiment, the writing performance of healthy participants with a hyperechogenicity of the substantia nigra as detected by transcranial sonography (TCS) was compared with the performance of healthy participants with low echogenicity of the substantia nigra. The third experiment examined the effect of central dopamine reduction on kinematic aspects of handwriting movements in healthy adults using acute phenylalanine and tyrosine depletion (APTD). A digitising tablet was used for the assessment of handwriting movements. Participants were asked to perform a simple writing task. Movement time, distance, velocity, acceleration and measures of fluency of handwriting movements were measured. The kinematic analysis of handwriting movements revealed that alterations of central dopaminergic neurotransmission adversely affect movement execution during handwriting. In comparison to the automatic processing of handwriting movements displayed by control participants, participants with an altered dopaminergic neurotransmission shifted from an automatic to a controlled processing of movement execution. Central dopamine appears to be of particular importance with regard to the automatic execution of well-learned movements.     

Disruption of semantic influence on writing following a left prefrontal lesion

We report a patient with impaired spontaneous writing, written naming, and homophone spelling, consistent with a disruption of semantic influence on writing. However, writing to dictation by both the phonological and lexical spelling systems was intact. In addition, general semantic abilities were spared, as indicated by preserved auditory and reading comprehension. We propose that our patient could not incorporate meaning into writing because of a disruption of both direct and indirect connections between semantics and the orthographic output lexicon. The writing dysfunction was accompanied by a similar impairment of speech output, suggesting that it was part of a more general disturbance of semantic influence on language production following left prefrontal damage.     

Semantic abilities in dementia of the Alzheimer type. 1. Lexical semantics

The lexical semantic abilities of 18 Alzheimer patients were investigated using confrontation naming tasks (including both visual and tactile naming tests) and compared to those of a group of institutionalized, nonneurologically impaired control subjects matched for age, sex, and educational level. The Alzheimer patients produced a greater number of naming errors than the control subjects. The errors made by subjects during the naming tasks were analyzed according to a set of 16 error response types. The Alzheimer patients' response patterns suggest that they do recognize objects which they are unable to name and are able to identify the semantic class to which the target belongs, but cannot provide the lexeme corresponding to the correct individual class member. The results support a semantic network disruption rather than a visual perceptual deficit as the basis of the naming disturbance observed in Alzheimer patients.     

Execution and pauses in writing narratives: processing time, cognitive effort and typing skill

At the behavioural level, the activity of a writer can be described as periods of typing separated by pauses. Although some studies have been concerned with the functions of pauses, few have investigated motor execution periods. Precise estimates of the distribution of writing processes, and their cognitive demands, across periods of typing and pauses are lacking. Furthermore, it is uncertain how typing skill affects these aspects of writing. We addressed these issues, selecting writers of low and high typing skill who performed dictation and composition tasks. The occurrences of writing processes were assessed through directed verbalization, and their cognitive demands were measured through interference in reaction times (IRT). Before writing a narrative, 34 undergraduates learned to categorize examples of introspective thoughts as different types of activities related to writing (planning, translating, or revising). Then, while writing, they responded to random auditory probes, and reported their ongoing activity according to the learned categories. Convergent with previous findings, translating was most often reported, and revising and planning had fewer occurrences. Translating was mostly activated during motor execution, whereas revising and planning were mainly activated during pauses. However, none of the writing processes can be characterized as being typical of pauses, since translating was activated to a similar extent as the other two processes. Regarding cognitive demands, revising is likely to be the most demanding process in narrative writing. Typing skill had an impact on IRTs of motor execution. The demands of execution were greater in the low than in the high typing skill group, but these greater demands did not affect the strategy of writing processes activation. Nevertheless, low typing skill had a detrimental impact on text quality.     

Task set persistence modulates word reading following resolution of picture-word interference

We extend the finding that word reading slows following successful responses to a color-word Stroop interference task (Masson, Bub, Woodward, & Chan, 2003). Word reading was assessed in a picture-word interference task in which subjects alternated between naming a picture (with either a word or a row of Xs superimposed on it) and reading a word. For the word-reading task, words were presented either in isolation or superimposed on a picture. Word reading was slower after subjects responded to a bivalent stimulus that required resolution of conflict (naming a picture with a word superimposed on it) than after they responded to a stimulus that involved no conflict (naming a picture with Xs superimposed on it), indicating modulation of dominant task performance. This effect was found when word-reading targets were superimposed on pictures but not when those targets were presented in isolation. Modulation of word reading, therefore, appears to be the result of interference from a persistent picture-naming task set, cued by a stimulus configuration that invites execution of both competing tasks.     

听障者语音编码的研究范式述评

对于健听者而言,语音编码在阅读中具有重要作用。听障者在阅读中是否存在语音编码？对于拼音文字而言,这个问题目前国际上存在很大的争议。中国听障者在阅读中是否使用了语音编码也逐渐开始受到重视。为了给国内研究听障者语音编码的学者提供参考,本文介绍了考察听障者语音编码研究中常用的研究范式,包括实验程序、逻辑及相应的研究成果。最后,对今后我国听障者语音编码的研究进行了展望。     

Developmental trends in speed accuracy trade-off in 6-10-year-old children performing rapid reciprocal and discrete aiming movements

Cyclic tasks are performed better than discrete tasks in adults but it is unknown whether this advantage is present in children as well. Three age groups of participants (6, 8, and 10 years old) executed cyclic and discrete aiming movements to two differently sized target using a Fitts task to examine the developmental effects on speed/accuracy trade-off. Children showed the same advantage of cyclic over discrete movements as previously demonstrated for adults but at a slower speed. The slope of the speed accuracy trade-off was similar in the three age groups in the cyclic as compared to the discrete control mode, suggesting that children learn both tasks equally well in this age range. The index of performance (IP) increased with age but not differently for the two control modes. Children showed clear differences between the kinematics of discrete and cyclic movements and these differences were similar to those seen in adults. Cyclic movements were faster, had higher IP, showed fewer changes in velocity and were more ballistic. Thus movement execution was different between the two tasks, consistent with the hypothesis that cyclic tasks make use of neural oscillators. The slower movement speed in young children is consistent with their limited ability to use open loop control.     

Classifying by dimensions and reading: a comparison of the auditory and visual modalities

Children have difficulty learning to read alphabetic writing systems, in part, because they have difficulty segmenting spoken language into phonemes. Young children also have difficulty attending to the individual dimensions of visual objects. Thus, children's early difficulty in reading may be one sign of a general inability to selectively attend to the parts of any perceptual wholes. To explore this notion, children in kindergarten through fourth grade (Experiments 1, 3, and 4) and adults (Experiment 2) classified triads of spoken syllables and triads of visual objects. Classifying speech by common parts was positively related to reading and spelling ability (Experiments 1 and 4), but usually not to classifying visual stimuli by common parts under free classification instructions (Experiments 1 through 3). However, classification was more consistent across the visual and auditory modalities when the children were told to classify based on a shared constituent (Experiment 4). Regardless of instructions, performance on the visual tasks did not usually relate to reading and spelling skill. The ability to attend selectively to phonemes seems to be a "special" skill--one which may require specific experiences with language, such as those involved in learning to read an alphabetic writing system.     

The interruptive effect of pain on attention

Pain is known to disrupt attentional performance in both healthy adults and patients with chronic pain. Exactly which aspects of attentional function are affected are, however, still to be determined. The primary aim of this investigation was to systematically examine the effects of experimentally induced pain on a range of attentional performance tasks. Following a review of tests of attentional disruption, seven best candidate tasks were selected and examined across seven experiments. The tasks were: continuous performance, flanker, endogenous precueing, n-back, inhibition, attentional switching, and divided attention. Healthy adult participants performed each of these tasks under three different conditions: a painful heat sensation, a warm heat sensation, and a nonheat control. Pain differentially affected attentional performance across these tasks; pain-related attentional impairment was found on the n-back, attentional switching, and divided attention tasks, but not on the other tasks. This finding suggests that the aspects of attention most affected by pain are those essential for the completion of complex tasks that require the processing of multiple cues and control over attentional deployment. These results are discussed in the context of an emerging view of pain as a demand for executive control and the development of measures that could be used to examine attentional disruption in the context of pain.