儿童的最早记忆特征及其与早期记忆数量的关系

本研究采用记忆流畅性任务和回忆最早记忆的方式考察了9岁和13岁共60名中国城镇独生儿童的早期记忆特征及各特征之间的关系。结果发现:(1)和西方研究相比,中国儿童回忆最早记忆时更多自发提及他人,尤其是父母。(2)最早记忆年龄与早期记忆数量有显著负相关,最早记忆中关于重要他人的记忆容量、社会取向和道德情绪与早期记忆数量有显著正相关。这些结果说明文化渗透对自传体记忆发生的影响,以及提示无论是最早记忆的质量,还是早期记忆的数量,回忆童年记忆背后可能潜藏着共同机制。     

Assessing working memory and language comprehension in Alzheimer's disease.

Studies of language impairments in patients with Alzheimer's disease have often assumed that impairments in linguistic working memory underlie comprehension deficits. Assessment of this hypothesis has been hindered both by vagueness of key terms such as "working memory" and by limitations of available working memory tasks, in that many such tasks either seem to have little relationship to language comprehension or are too confusing or difficult for Alzheimer's patients. Four experiments investigated the usefulness of digit ordering, a new task assessing linguistic working memory and/or language processing skill, in normal adults and patients with probable Alzheimer's disease. The digit ordering task was shown to be strongly correlated with the degree of dementia in Alzheimer's patients. The task correlated with measures of language processing on which patients and normal controls performed differently. The results are interpreted as indicating that linguistic representations, linguistic processing, and linguistic working memory are intertwined, such that a deficit of one (e.g., working memory) cannot be said to "cause" a deficit in the other. The implications of this approach are explored in terms of task demands in comprehension and memory measures, and interpretation of previous results in the literature.     

Memories from the cradle

How far back can we, as adults, remember details of our life experiences? Current popular and scientific beliefs are contradictory, with the latter stipulating that personal memories do not begin until the late preschool years (age 4–5 years) and the former claiming that we not only remember being born, but can also remember in utero experiences. In this review, these beliefs are examined in a scientific context and evaluated in terms of empirical data about the development of early memory. The theory proposed here is that memories for personal experiences are not possible until the advent of the cognitive self, around the age of 18 to 24 months. This age is much earlier than that proposed as the age of the earliest memories in other scientific accounts and much later than that proposed in popular beliefs about early memory. New data from a cross-sectional and longitudinal study of early memory development and the emergence of the self clearly show the origins of personal memory coincide with the emergence of the early self.     

Parental influences on earliest memories

Recently, independent lines of research have indirectly supported the notion that social variables, especially parent-child relationships, have a significant impact on adults' memories of their early life. In order to directly assess this Italian students were asked to recall as many memories involving parents as they could from before the age of 6 in a 3-minute timed recall task (i.e., memory fluency). They also filled out assessments about parental involvement in their lives as well as the quality of their relationships with their mothers and fathers. We found that, for males, the more involved the parents and the warmer the relationships between sons and both their mothers and their fathers, the more early memories, the more positive early memories, and the more episodic memories men recalled. For women, the warmer the relationship with their mothers, the earlier their earliest memory. Results are discussed in terms of gendered parent-child interactions as well as McAdam's emergent life-story theory.     

Parental influences on earliest memories

Recently, independent lines of research have indirectly supported the notion that social variables, especially parent–child relationships, have a significant impact on adults’ memories of their early life. In order to directly assess this Italian students were asked to recall as many memories involving parents as they could from before the age of 6 in a 3-minute timed recall task (i.e., memory fluency). They also filled out assessments about parental involvement in their lives as well as the quality of their relationships with their mothers and fathers. We found that, for males, the more involved the parents and the warmer the relationships between sons and both their mothers and their fathers, the more early memories, the more positive early memories, and the more episodic memories men recalled. For women, the warmer the relationship with their mothers, the earlier their earliest memory. Results are discussed in terms of gendered parent–child interactions as well as McAdam's emergent life-story theory.     

Discrete changes in the frequency and functions of autobiographical reminiscence in Huntington's disease

ABSTRACT

Autobiographical memory is widely posited to serve self, social and directive functions. Recent evidence suggests marked autobiographical memory impairments in Huntington's disease (HD), however, no study to date has determined how the perceived functions of autobiographical reminiscence may be altered in HD. The current study aimed to assess the self-reported frequency and function of autobiographical reminiscence in HD. We assessed autobiographical reminiscence in late premanifest (n?=?16) and early stage HD (n?=?14), relative to healthy controls (n?=?30). Participants completed the Thinking About Life Experiences Scale Revised (TALE-R), which measures three putative functions of autobiographical memory (self, social, directive). People with manifest HD reported talking less frequently about the past compared to controls. In contrast, no group differences were found in terms of thinking about the past. Manifest HD participants further reported using their autobiographical memories for social functions less frequently compared to controls. No other group differences were evident in terms of self or directive functions of autobiographical memory. These self-report findings complement recent reports of autobiographical memory disruption on performance-based tasks in HD. Future studies exploring how changes in autobiographical reminiscence impact a sense of self continuity in HD will be important in this regard.     

The cholinergic lesion of Alzheimer's disease: pivotal factor or side show?

A profound loss of cortical cholinergic innervation is a nearly invariant feature of advanced Alzheimer's disease (AD). The temporal course of this lesion and its relationship to other aspects of the disease have not yet been fully clarified. Despite assertions to the contrary, a review of the evidence suggests that a perturbation of cholinergic innervation is likely to be present even in the very early stages of AD. This cholinergic lesion is unlikely to be a major determinant of the clinical symptoms or of the neuropathological lesions. Nonetheless, it almost certainly contributes to the severity of the cognitive and behavioral deficits, especially in the areas of memory and attention. The cholinergic lesion may also influence the progression of the neuropathological process through complex interactions with amyloidogenesis, tau phosphorylation and neuroplasticity.     

Evidence for a shrinking span of personal and present existence in dementia of the Alzheimer's type

Severely impaired episodic memory deprives patients with Alzheimer's disease (AD) of a sense of personal continuity in their daily lives, yet there are no tests that accurately measure this impairment. Recently, Zakzanis, Leach, and Moscovitch (1999) examined the integrity of memory function in terms of temporal continuity in a way that would engage the patient in everyday behavior, such as informal conversation, but still allow memory function to be quantified. The task allowed the measurement of the duration of continuous, conscious experience of the present and was therefore termed "span of temporal continuity (STC)." Given that we were able to document static and growing STCs, we wanted to know whether our measure could track progressive memory loss. Accordingly, we followed a patient we believed was in the very early stages of AD to measure the change of his STC longitudinally. Along with his STC, we present our neuropsychological and brain imaging findings over the course of the investigation.     

Lexical and semantic fluency discrepancy scores in aMCI and early Alzheimer's disease

Episodic memory is compromised in amnestic mild cognitive impairment (aMCI), but lesser deficits in other cognitive domains are also commonly observed and may be helpful in identifying this group. The relative difference in performance on lexical and semantic fluency tasks may be a sensitive and specific measure in aMCI and early Alzheimer's disease (AD). We compared four groups of participants, 35 early AD, 47 aMCI, 24 healthy controls, and 18 depressive out‐patient controls, on semantic and lexical fluency as well as other neuropsychological tests. Early AD and aMCI patients showed a distinct pattern of semantic impairment in the two fluency measures compared with the healthy and depressive controls. The findings implicate early failure of the semantic memory system in aMCI and AD and suggest that consideration of the discrepancy in performance on semantic and lexical fluency measures may help in the early identification of AD.     

Children’s autobiographical memories across the years: Forensic implications of childhood amnesia and eyewitness memory for stressful events

This is a review of two bodies of research conducted by myself and my colleagues that is relevant to child witness issues, namely childhood amnesia and children’s eyewitness memory for stressful events. Although considerable research over the years has investigated the phenomenon of childhood amnesia in adults, only recently has it begun to be investigated in children. For them, the age of earliest memory is a moving target over their early years. However, there is nonetheless both variation between children in how early their first memories are as well as variation between memories in terms of likelihood of being retained, and some factors influencing both are explored. In terms of eyewitness memory for stressful events, 2–13-year-old children who had been injured seriously enough to require emergency room medical treatment were interviewed. Long-term memory for these stressful events was traced, and factors influencing that retention were investigated. The findings from both areas of research have implications for developmental forensic psychology.     

The role of conscious memory in the category-production task

This study reported two experiments using the category-production task to examine the role of conscious memory in the conceptual indirect test of memory. Experiment 1 tested participants on both the category-production and recall tasks and found that, when participants were given ample time to do the production task, their production performance could be fully accounted for by their recall performance. On the other hand, priming was still found in the early production when intentional retrieval was unlikely to occur, indicating the influence of involuntary memory. Experiment 2 replicated the main finding of Experiment 1. More importantly, evidence from the exclusion instruction condition showed that there was no involuntary unconscious memory. These two experiments also demonstrated a dissociation of the delay effect between the category-production and recall tests, as well as a parallel levels-of-processing effect on these two tests. Results are discussed in terms of the nature of priming in the conceptual indirect test.     

Normal McCollough effect in Alzheimer’s disease and global amnesia

The McCollough effect (ME), a long-lasting, pattern-contingent aftereffect in normal human vision, was examined in persons with known deficits in memory. We induced MEs in 11 subjects, 5 patients with various severities of Alzheimer’s disease (AD), H.M. (a patient who has global amnesia due to bilateral medial temporal lobectomy and who has been studied for 35 years since his operation), and 5 control subjects. H.M. and the AD patients showed MEs of strength and duration comparable to those of the control subjects. These results demonstrate a dissociation between learning mechanisms that mediate recall and recognition versus mechanisms that mediate the ME. Furthermore, knowledge about the sites of neuropathology in H.M. and in AD are consistent with other sources of evidence implicating early visual areas, especially V1, as a critical locus of the ME.     

Normal McCollough effect in Alzheimer's disease and global amnesia

The McCollough effect (ME), a long-lasting, pattern-contingent aftereffect in normal human vision, was examined in persons with known deficits in memory. We induced MEs in 11 subjects, 5 patients with various severities of Alzheimer's disease (AD), H.M. (a patient who has global amnesia due to bilateral medial temporal lobectomy and who has been studied for 35 years since his operation), and 5 control subjects. H.M. and the AD patients showed MEs of strength and duration comparable to those of the control subjects. These results demonstrate a dissociation between learning mechanisms that mediate recall and recognition versus mechanisms that mediate the ME. Furthermore, knowledge about the sites of neuropathology in H.M. and in AD are consistent with other sources of evidence implicating early visual areas, especially V1, as a critical locus of the ME.     

Working Memory and Learning in Early Alzheimer’s Disease

Cognitive deficits associated with early Alzheimers disease (AD) have been recently operationalised in terms of an acquisition deficit and the research supporting this view is presented. However, there is still debate concerning the nature of this deficit and how underlying cognitive processes may be detrimentally affecting the ability to acquire new information in early AD. This review argues that the pattern of cognitive deficits contributing to the acquisition impairment in early AD patients may be readily interpreted within the context of a working memory model. Isolating the component processes of working memory that underlie the acquisition deficit in early AD patients will aid in the design of clinical applications that are focussed at enhancing the ability to acquire new information in everyday life.     

The effect of vertical and horizontal symmetry on memory for tactile patterns in late blind individuals

Visual stimuli that exhibit vertical symmetry are easier to remember than stimuli symmetric along other axes, an advantage that extends to the haptic modality as well. Critically, the vertical symmetry memory advantage has not been found in early blind individuals, despite their overall superior memory, as compared with sighted individuals, and the presence of an overall advantage for identifying symmetric over asymmetric patterns. The absence of the vertical axis memory advantage in the early blind may depend on their total lack of visual experience or on the effect of prolonged visual deprivation. To disentangle this issue, in this study, we measured the ability of late blind individuals to remember tactile spatial patterns that were either vertically or horizontally symmetric or asymmetric. Late blind participants showed better memory performance for symmetric patterns. An additional advantage for the vertical axis of symmetry over the horizontal one was reported, but only for patterns presented in the frontal plane. In the horizontal plane, no difference was observed between vertical and horizontal symmetric patterns, due to the latter being recalled particularly well. These results are discussed in terms of the influence of the spatial reference frame adopted during exploration. Overall, our data suggest that prior visual experience is sufficient to drive the vertical symmetry memory advantage, at least when an external reference frame based on geocentric cues (i.e., gravity) is adopted.     

Exemplar effects in categorization and multiple-cue judgment

Categorization and multiple-cue judgment are similar tasks, but the influential models in the two areas are different in terms of the computations, processes, and neural substrates that they imply. In categorization, exemplar memory is often emphasized, whereas multiple-cue judgment generally is interpreted in terms of integration of cues that have been abstracted in training. In 3 experiments the authors investigated whether these conclusions derive from genuine differences in the processes or are accidental to the different research methods. The results revealed large individual differences and a shift from exemplar memory to cue abstraction when the criterion is changed from a binary to a continuous variable, especially for a probabilistic criterion. People appear to switch between qualitatively distinct processes in the 2 tasks.     

A cognitive model in which representations are images

Interpretations of images of the brain are starting to reveal the conceptual tasks in which the person was engaged at the time of imaging. Existing mathematical models can explain the patterns of activity observed in such images in terms of the coherent activity of large populations of neurons, but not in terms of cognition. This paper is an early investigation into how such patterns might provide the internal representations for a cognitive system. Probes, working memories and memories are all represented as images. The accompanying process model describes how attention is set according to the contents of working memory, how attention determines what parts of the probe are memorised, how memories are activated according to similarity to the probe in areas in attention, and how working memory is managed. The model is demonstrated on re-creations of classic simulations of recognition memory and categorisation.     

Adaptive Memory: Fitness Relevance and the Hunter-Gatherer Mind

ABSTRACT— Recent studies suggest that human memory systems are "tuned" to remember information that is processed in terms of its fitness value. When people are asked to rate the relevance of words to a survival scenario, performance on subsequent surprise memory tests exceeds that obtained after most other known encoding techniques. The present experiments explored this effect using survival scenarios designed to mimic the division of labor thought to characterize early hunter-gatherer societies. It has been suggested that males and females have different cognitive specializations due to the unique survival tasks (hunting and gathering, respectively) they typically performed during periods of human evolution; the present experiments tested whether such specializations might be apparent in memory for words rated for relevance to these activities. Males and females were asked to rate the relevance of random words to prototypical hunting and gathering scenarios or to matched, non-fitness-relevant control scenarios (gathering food on a scavenger hunt or in a hunting contest). Surprise retention tests revealed superior memory for the words when they were rated for relevance to hunting and gathering scenarios, compared with when they were rated for relevance to the control scenarios, but no sex differences were found in memory performance.     

数字空间表征的在线建构：来自干扰情境中数字SNARC效应的证据

尽管已有研究发现数字以空间方式表征在人类记忆系统, 但是人脑如何完成数字的空间表征尚存争议。本研究两个实验在不同比例的数字字母(实验1)和不同比例的数字汉字(实验2)混合情境中考察了数字空间表征特点及其机制, 对上述争议进行了深入研究。结果发现：(1)当数字字母比例为“1 : 1”时, 数字加工中不出现SNARC效应。当数字字母比例为“1 : 6”和“6 : 1”时, 数字加工中均出现SNARC效应。即数字字母比例与数字SNARC效应之间呈倒“U”型关系。(2)数字汉字混合情境中数字汉字比例与数字SNARC效应之间同样呈倒“U”型关系。结果说明：(1)干扰刺激与数字混合呈现会影响数字SNARC效应。(2)干扰刺激加工对数字SNARC效应的影响受到数字与干扰刺激比例的调节, 且具有跨干扰材料的稳定性。研究结果意味着数字的空间表征是人类通过统计学习在线建构的, 支持了工作记忆理论。