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Myriad Genetics holds a patent on testing for the hereditary breast and ovarian cancer genes, BRCA1 and BRCA2, and therefore has a forced monopoly on this critical genetic test. Myriad launched a Direct-to-Consumer (DTC) marketing campaign in the Northeast United States in September 2007 and plans to expand that campaign to Florida and Texas in 2008. The ethics of Myriad's patent, forced monopoly and DTC campaign will be reviewed, as well as the impact of this situation on patient access and care, physician liability, and the future of DTC campaigns for genetic testing.  相似文献   

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Even though psychological treatments have been advocated as treatments for a range of mental disorders by the WHO for scaling up through primary care globally, the vast majority of potential beneficiaries are unable to access these treatments. Two major barriers impede the path between evidence based treatments and improved access: the lack of skilled human resources and the acceptability of treatments across cultures. This essay synthesizes the experiences of programs which developed and evaluated psychological treatments for depression in three resource poor developing countries. These programs addressed the human resource barrier by training lay or community health workers to deliver the treatments and addressed the acceptability barrier by systematically adapting the treatment to contextual factors. All programs demonstrated significant benefits in recovery rates when compared with usual care demonstrating the effectiveness of the approach. The implications for these experiences to improving access to psychological treatments in the global context are discussed.  相似文献   

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A brief review of the major psychological refractory period (PRP) theories reveals that they have lost their original objective, i.e., to explain human information processing under rapid sequential stimulation. Conventional data interpretation has restricted attention to delay of reaction times as a result of interstimulus interval (ISI) variation. This form of data interpretation fails to capture important performance aspects under double-stimulation, e.g., the phenomenon that stimulus complexity affects the processing rate. Effects of stimulus rate and complexity are better analyzed in terms of reaction times as well as interresponse intervals (IRI). If this is done, behavioral phenomena emerge that cannot be explained within the frame of any of the existing PRP theories. To account for these newly revealed phenomena a processing interrupt model is introduced which is based on three major hypotheses: single-channel processor, additive stages, and perceptual interrupt facility.  相似文献   

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An explication of common sense is an attempt to formulate a part of the ordinarily unformulated system of implications shared by all members of a given culture, familiar with a given context. Thirty-six alleged common sense formulations relating to Bandura's theory of self-efficacy were used. Students were asked 1) to give a prediction involving each theorem, 2) to judge whether or not an alternative prediction is conceivable, 3) to judge whether or not an explanation based on the theorem is acceptable, and 4) to judge whether or not an explanation based on the negation of the theorem is acceptable. The average consensus on these four types of judgments was respectively 93%, 80%, 92%, and 96%. A group of respondents were interviewed about the shortcomings of the formulations. The theorems were revised to incorporate these criticisms and, hence, are expected to yield higher consensus.  相似文献   

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In order to assess the utility of the Mini-Mult with a university counseling center clientele, MMPI answer sheets of 10 students at the University of Miami Counseling Center were scored for both the MMPI and the Mini-Mult. Four judges completed psychological reports (Q-item questionnaires) based on the profiles. Correlations between judges' responses to MMPI and Mini-Mult profiles were calculated as an indication of the correspondence between the two tests. In addition, correlations between judges' responses to repeated presentations of MMPI profiles were calculated as an indication of the judges' reliability over time. The results do not support the use of the Mini-Mult with a university counseling center clientele.  相似文献   

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The evidence-based practice (EBP) movement has the potential to significantly advance the quality of psychological and educational services provided by psychologists working in schools. Training psychologists in EBP has challenged the profession and caused faculty in graduate programs to reevaluate and retool professional training curricula and instructional practices. Four domains of challenges in graduate training are identified: (a) integrating the EBP knowledge base into the curriculum, (b) expanding models of research training, (c) expanding training in prevention science, and (d) expanding training in problem-solving consultation and school contextual issues. For each of these, the author discusses the range and scope of the challenge and possible solutions for advancing graduate training in psychology relevant to school practice.  相似文献   

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Multisystemic therapy (MST) is a family-based treatment model that has achieved high rates of treatment completion with youths who present serious clinical problems, and their families. The success of MST in engaging challenging families in treatment is due to programmatic commitments to family collaboration and partnership as well as to a conceptual process that delineates barriers to family engagement, develops and implements strategies to overcome these barriers, and evaluates the success of these strategies. This article provides an overview of the nonspecific/universal engagement strategies used by MST therapists, frequently observed barriers to achieving therapist-family engagement, and specific strategies to overcome a sampling of these barriers.  相似文献   

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Recent statistical analyses of the relation of the MMPI surface traits to the source traits in the 16 P.F. were extended to (a) the calculation of beta weights for estimating MMPI scale scores from the 16 P.F. and (b) deriving the MMPI item composition in terms of 16 P.F. scores from the MMPI, and vice versa. It has been argued from the specific nature of surface and source traits that additional diagnostic insight can be gained from their comparison, a principle which has been designated as depth psychometry.  相似文献   

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