The stages-of-change approach for prosocial behavior: Message tailoring to encourage blood donation

This research applied the Trans-Theoretical Model and the Construal Level Theory to framing messages for blood donation. People can be at different degrees of readiness for blood donation and are, therefore, dispersed into discrete stages of change. These stages of change correspond to varying psychological distances that define the extent to which a person's thinking on the suggested behavior is abstract (high construal level) or concrete (low construal level). Differences in psychological distance thus affect whether individuals focus on how easy it is to donate blood (feasibility) or on why it is important to donate blood (desirability) in the ad message. This research conducted two studies using a 2 (types of message: feasibility vs. desirability—manipulated) × 3 (stages of change: pre-contemplation vs. contemplation/preparation vs. action/maintenance—measured) between-subject, randomly assigned factorial design experiment. The results of both studies showed that for individuals in the pre-contemplation stage, desirability, rather than feasibility, messages were more likely to produce favorable attitudes toward the ad, its sponsoring organization, and blood donation behavior itself, whereas the opposite was true for those in the action/maintenance stage. Those differences were weakened or not observed for those in the contemplation/preparation stage. These patterns of interaction were not replicated for behavioral intention. Collectively, these findings suggest that tailoring a message according to the intended audience's stage of change should promote positive attitudes for blood donation. Meanwhile, future research is needed to bridge the attitude-behavior gap when it comes to blood donation.     

Assessing the risk of ovarian hyperstimulation syndrome in egg donation: implications for human embryonic stem cell research

Stem cell research has important implications for medicine. The source of stem cells influences their therapeutic potential, with stem cells derived from early-stage embryos remaining the most versatile. Somatic cell nuclear transfer (SCNT), a source of embryonic stem cells, allows for understandings about disease development and, more importantly, the ability to yield embryonic stem cell lines that are genetically matched to the somatic cell donor. However, SCNT requires women to donate eggs, which involves injection of ovulation-inducing hormones and egg retrieval through laparoscopy or transvaginal needle aspiration. Risks from this procedure are fiercely debated, most notably risk of ovarian hyperstimulation syndrome (OHSS). This review examines risk of OHSS resulting from oocyte donation. We conclude that risk posed by OHSS in egg donation is not significant enough to warrant undue concern, and much of this can be eliminated when proper precautions are taken. This bears relevance to the future of stem cell research policymaking.     

Oversight framework over oocyte procurement for somatic cell nuclear transfer: comparative analysis of the Hwang Woo Suk case under South Korean bioethics law and U.S. guidelines for human embryonic stem cell research

We examine whether the current regulatory regime instituted in South Korea and the United States would have prevented Hwang’s potential transgressions in oocyte procurement for somatic cell nuclear transfer, we compare the general aspects and oversight framework of the Bioethics and Biosafety Act in South Korea and the US National Academies’ Guidelines for Human Embryonic Stem Cell Research, and apply the relevant provisions and recommendations to each transgression. We conclude that the Act would institute centralized oversight under governmental auspices while the Guidelines recommend politically-independent, decentralized oversight bodies including a special review body for human embryonic stem cell research at an institutional level and that the Guidelines would have provided more vigorous protection for the women who had undergone oocyte procurement for Hwang’s research than the Act. We also suggest additional regulations to protect those who provide oocytes for research in South Korea.     

Constructing isoluminant stimuli for word recognition research: A precautionary study

Isoluminant stimuli are used increasingly often to investigate processes underlying visual word recognition. However, construction of isoluminant stimuli is not straightforward, and inappropriate construction may have the result of misinforming theories that relate word recognition to neurological function. To inform the use of isoluminant stimuli in studies of word recognition, the present article details two experiments in which isoluminant stimuli were constructed using physical onscreen luminance matching and heterochromatic flicker photometry (HFP) with four different stimulus types: disks, squares, rectangles, and letter strings. The findings reveal (1) substantial differences between isoluminance determined by physical onscreen luminance matching and HFP, (2) substantial differences in HFP isoluminance across stimulus types, and (3) substantial differences in HFP isoluminance across participants. These findings indicate that, in contrast to common practice in word recognition research, HFP provides a better indication of isoluminance than physical onscreen matching; but HFP stimuli should match those used in the experiment proper and should be used to assess isoluminance individually for each participant.     

A trilevel approach to motivators for retraining

A three-level taxonomy of the reasons for vocational retraining is proposed. The compliance level is characterized by the necessity of immediate acquisition of a profession. At the identification level retraining is motivated by the need for a satisfying self-definition through the profession. With the internalization level the profession is chosen to suit one's capabilities and self-fulfillment. Participants in retraining programs filled out the following questionnaires: locus of control, vocational maturity attitudes, level of motivation for retraining, evaluation of the retraining program, and new job satisfaction. Internalization level motivators positively correlated with internal locus of control and vocational maturity attitudes. No such correlations were found for identification or compliance level. Subjects who retrained because of high compliance motivation were less satisfied by the programs, more inclined to drop out, and less apt to seek employment in jobs for which they had retrained than those high on the other levels of motivation. No difference in job satisfaction was determined for those who did work in the new profession.     

Salutary effect of daily coping self-efficacy: impact on day-by-day coping to mood effects within dyads following hematopoietic stem cell transplantation

ABSTRACT

Background and Objectives: Little is known how coping self-efficacy (CSE) interacts with coping in dyad everyday life. The present study examined the moderating role of daily CSE in the relationship between coping and the next-day positive (PA) or negative (NA) affect in patient-caregiver dyads, following hematopoietic stem cell transplantation.

Design: This intensive longitudinal study was conducted during the first 28 days after post-transplant discharge.

Methods: Patients and their caregivers (N?=?200) maintained daily diaries on CSE, coping strategies, and affect.

Results: Daily CSE moderated daily coping–affect relationship: Positive emotion-focused coping increased PA in patients with higher than usual emotion-related CSE, whereas a buffering effect was found at lower than usual emotion-related CSE. A positive association between negative emotion-focused coping and NA in both patients and caregivers was stronger among those with lower than usual levels of emotion-related CSE. Higher than usual instrumental coping reduced NA in patients whose caregivers had higher than usual problem-related CSE, but increased NA for those whose caregivers had lower than usual instrumental CSE.

Conclusion: The findings show that daily CSE contributes to the effectiveness of daily coping within dyad, confirming its significance in effective adaptation and the role in the dyadic coping process.     

Impact of outpatient non-myeloablative haematopoietic stem cell transplantation in quality of life vs. conventional therapy

The role of outpatient hematopoietic stem cell transplantation (HSCT) as a therapeutic tool has been strengthened significantly because of the increasing number of patients undergoing this treatment. Due the very nature of this procedure, one of the aspects that should not be overlooked is the quality of life (QOL) of patients undergoing HSCT. Thus, one must consider not only health status after treatment, but also, the psychosocial implications for the patient. This is an observational, longitudinal, and prospective study to assess QOL in patients undergoing outpatient HSCT vs. similar patients receiving medical treatment (MxTx). By applying the COOP/WONKA charts on five occasions (pre-HSCT/initial, post-HSCT/first month, and at 3, 6, and 9 months), thirty-eight patients were analysed, 19 with HSCT and 19 with MxTx with no differences in age, gender or diagnosis. The initial survey found significant differences only in pain perception, which was higher in the HSCT group (p = .08); at the first month, there was a greater tendency for feelings of depression or anxiety in the HSCT group (p = .016), with more limitations in social (p = .003) and daily (p = .044) activities. From 3 months post-HSCT, the results were very similar. The differences persisted only in the area of social activities. Four patients developed graft-versus-host disease with no significant difference in the scores obtained compared to other transplant patients at 3, 6, and 9 months (p = .26) of follow-up.     

Problematic donation procedures vs. futuristic research and treatment applications: A dichotomous social representation of stem cells in Italy

IntroductionCurrently, stem cells (SC) are one of the most studied issues of medical research as well as a widespread, complex, socially and ethically relevant issue.ObjectiveThe general aim of the present study is to explore how social representations (SR) of SC is different for people more or less willing to donate SC, also comparing bone marrow SC (BMSC) donation and umbilical cord blood SC (UCBSC) donation.MethodA paper-and-pencil survey was administrated to 78 Italian respondents. A structural analysis of SC-SRs (prototypical and co-occurrence analysis) was conducted comparing people with a high/low intention to donate UCBSC/BMSC.ResultsSimilarly to other bioethically relevant issues, SR of SC seems to be ambivalent and dichotomously organized, with the donation procedure been a barrier.ConclusionThese results are in line with studies finding two sets of dichotomies: on the one hand, a gift-of-life/replacement-of-body-parts dichotomy coexisting within people's SR of organ donation; on the other hand, a help/pain and needle dichotomy within blood donation's SR. Directions for future research are suggested.     

A phenomenological approach to the ethics of transplantation medicine: sociality and sharing when living-with and dying-with others

Recent years have seen a rise in the number of sociological, anthropological, and ethnological works on the gift metaphor in organ donation contexts, as well as in the number of philosophical and theological analyses of giving and generosity, which has been mirrored in the ethical debate on organ donation. In order to capture the breadth of this field, four frameworks for thinking about bodily exchanges in medicine have been distinguished: property rights, heroic gift-giving, sacrifice, and gift-giving as aporia. Unfortunately, they all run into difficulties in terms of both making sense of the relational dimensions of postmortem and live organ donations and being normatively adequate in the sense of shedding light and providing guidance on ethical concerns when body parts are donated. For this reason, this article presents a phenomenological framework of giving-through-sharing, based on Maurice Merleau-Ponty’s philosophy. This framework makes sense of relational dimensions of postmortem and live organ donation. It also sheds light on three highly debated concerns in organ donation ethics: indebtedness on the part of recipients, the fact that some live donors do not experience donation as a matter of choice, and the potentially painful experience of donors’ relatives, who need to make decisions about postmortem organ donation at a time of bereavement. It can indirectly support what may be called a normalization of bodily exchanges in medicine.     

A pavlovian approach to psychiatry

The basic scientific discovery made by Pavlov, namely the differentially associated paired system comprising related positive and negative conditioned signals based upon inborn reflex systems, has been applied to normal, neurotic and psychotic states. A hypothesis is suggested as to the causation of neurotic and psychotic disorder. The differentially associated paired systems based upon the reproductive reflexes have to be reversed at puberty in the course of maturation and this disrupts normal function. This is not incompatible with Freudian ideas where “unconscious incestuous wishes, drives and guilt” are believed to be potent factors in the production of functional disorders. Freudian “life instincts” are equated with normal differentially associated paired systems and “death instincts” are equated with those paired systems in a state of reversal (ultraparadoxical phase).     

A psychological approach to ethics

This article has the purpose of calling attention to C.G. Jung's archetypal concept of the Self as an approach to ethics. The distinction between simple morality and transcendent ethics is established. Comparison is made between the archetype of the Self and Kant's categorical imperative. Freud's superego, however, is assimilated to a natural outlook on morality, such as the notion of altruism in sociobiology. The superego is only the psychic effect of the current moral code—which could be explained either culturally or as a Lamarckian acquired characteristic of the unconscious. Jung's transcendent ethics is expressed in an ethical mandala.     

A syntactical approach to modality

Conclusion The systems T _N and T _M show that necessity can be consistently construed as a predicate of syntactical objects, if the expressive/deductive power of the system is deliberately engineered to reflect the power of the original object language operator. The system T _N relies on salient limitations on the expressive power of the language L _N through the construction of a quotational hierarchy, while the system T _Mrelies on limiting the scope of the modal axioms schemas to the sublanguage L _infM ⁺, which corresponds exactly with the restrictive hierarchy of L _N. The fact that L _infM ⁺ is identical to the image of the metalinguistic mapping C ⁺ from the normal operator system into L _M reveals that iterated operator modality is implicitly hierarchical, and that inconsistency is produced by applying the principles of the modal logic to formulas which have no natural analogues in the operator development. Thus the contradiction discovered by Montague can be diagnosed as the result of instantiating the axiom schemas with modally ungrounded formulas, and thereby adding radically new modal axioms to the predicate system.The predicate treatment of necessity differs significantly from that of the operator in that the cumulative models for the predicate system are strictly first-order. Possible worlds are not used as model-theoretic primitives, but rather alternate models are appealed to in order to specify the extension of N, which is semantically construed as a first-order predicate. In this manner, the intensional aspects of modality are built into the mode of specifying the particular set of objects which the denotation function assigns to N, rather than in the specification of the basic truth conditions for modal formulas. Intensional phenomena are thereby localised to the special requirements for determining the extension of a particular predicate, and this does not constitute a structural modification of the first-order models, but rather limits the relevant class of models to those which possess an appropriate denotation function.     

A community-reinforcement approach to alcoholism

Several theoretical approaches to alcoholism exist. An opérant reinforcement approach was used in the present study to develop a new procedure that rearranged community reinforcers such as the job, family and social relations of the alcoholic such that drinking produced a time-out from a high density of reinforcement. The results showed that the alcoholics who received this Community-Reinforcement counseling drank less, worked more, spent more time with their families and out of institutions than did a matched control group of alcoholics who did not receive these procedures. This new approach appears to be an effective method of reducing alcoholism. An analysis in reinforcement terms is presented of the etiology, epidemiology, and treatment of alcoholism.