Executive Functioning in Children and Adolescents with Major Depressive Disorder

The present investigation examined neurocognitive functioning, focusing on executive functioning (EF), in 39 children and adolescents with Major Depressive Disorder (MDD) and 24 healthy control subjects all ages 8 to 17 years. The Wechsler Intelligence Scale for Children-Third Edition along with several measures of executive functioning including the Wisconsin Card Sorting Task, Trail Making Test, Controlled Oral Word Association Test, and the Stroop Color Word Test were administered. The neurocognitive profiles for the group of depressed children and adolescents were grossly intact as most scores on intellectual and EF measures fell within the average range and did not differ from the comparison group. Mental processing speed was decreased in the MDD versus normal control group and 27% of the depressed group performed below average on the Trail Making Test. This investigation provided a good base from which to compare future literature on EF in outpatients with early-onset MDD.     

Verbal Learning Strategies of Adolescents and Adults with the Syndrome of Nonverbal Learning Disabilities

Abstract

Although many psychometric studies of individuals with the syndrome of nonverbal learning disabilities (NLD) have been conducted, one relatively neglected area has been the study of their performance on explicit verbal memory measures. We examined the performance of adolescents and adults with NLD on the California Verbal Learning Test, a measure allowing analysis of self-initiated learning strategies, and compared their performance to age- and Full Scale IQ-matched verbal learning-disabled (VLD) controls. Mean performance of the NLD sample on the semantic clustering index fell one standard deviation below the normative mean, whereas their serial clustering score was within normal limits. Additionally, the serial clustering score for our NLD sample was significantly greater than their semantic clustering score, suggesting that these individuals are more likely to spontaneously employ serial verbal learning strategies as opposed to those that are semantically driven. This difference in serial versus semantic clustering scores was not seen in our VLD controls, who performed equally well, and within normal limits, on both indices.     

Virtual team leadership: The effects of leadership style and communication medium on team interaction styles and outcomes

This study investigated the effects of transformational and transactional leadership styles and communication media on team interaction styles and outcomes. Teams communicated through one of the following three ways: (a) face-to-face, (b) desktop videoconference, or (c) text-based chat. Results indicated that transformational and transactional leadership styles did not affect team interaction styles or outcomes; that the mean constructive interaction score was higher in FTF than videoconference and chat teams, but not significantly higher in videoconference than chat teams; and that teams working in richer communication media did not achieve higher task performance than those communicating through less rich media. Finally, mean team cohesion scores were higher in FTF and videoconference than chat teams, but not significantly higher in FTF than videoconference teams. These results provide further evidence that communication media do have important effects on team interaction styles and cohesion.     

Videoconference to supervise early intensive behavioral intervention: A preliminary evaluation of acceptability

At present, early intensive behavioral intervention (EIBI) for children with autism spectrum disorders is the intervention that has the strongest empirical support. EIBI requires frequent supervision by qualified professionals. Norway, like many other countries, has a shortage of qualified supervisors, particularly in rural regions. This study used a reversal design to investigate how supervisors and supervisees perceive the quality of EIBI supervision and the local team's preparedness when supervision was provided either on-site or via videoconference. Calculations were made on how much time could be saved on travel when part of the supervision was provided via videoconference. There were no significant differences in the supervisors' and supervisees' ratings of on-site and videoconference supervision. Moreover, the supervisors found the local EIBI teams to be better prepared when supervision was provided via videoconference, and the videoconference supervision meetings were shorter. The study discusses the implications of these findings for the accessibility of EIBI and case capacity and proposes some areas for further research.     

Pilot study of light therapy and neurocognitive performance of attention and memory in healthy subjects

The aim of this pilot study was to investigate whether light therapy improves healthy subjects' neurocognitive performance of attention, memory, and language. Ten subjects were treated with white bright light for 5 days and a control group of 10 with no treatment were assessed with a battery of neurocognitive tests which included the Stroop Colour Word Interference Test, the Verbal Fluency Test, the Story Recall Test, and the Word Pairs Recall Test. Analysis showed improvements in cognitive scores in both groups, although on all the cognitive tests the mean difference scores between baseline and endpoint were significantly larger in the light-treated group. These preliminary results suggest that short-term bright light may exert beneficial effects on cognitive functions.     

Beery-Buktenica Developmental Test of Visual-Motor Integration performance in children with traumatic brain injury and attention-deficit/hyperactivity disorder

Evaluation of visuoconstructional abilities is a common part of clinical neuropsychological assessment, and the Beery-Buktenica Developmental Test of Visual-Motor Integration (VMI; K. E. Beery & N. A. Beery, 2004) is often used for this purpose. However, few studies have examined its psychometric properties when used to assess children and adolescents with traumatic brain injury (TBI) or attention-deficit/hyperactivity disorder (ADHD), even though these are among the most common acquired and neurodevelopmental forms of brain dysfunction in children. This study examined the validity of VMI scores in 123 children with TBI and 65 with ADHD. The TBI and ADHD groups performed significantly worse than the standardization sample, obtaining VMI mean scores of 87.2 (SD = 13.7) and 93.5 (SD = 11.27). Previous research has noted decrements in visuoconstructional abilities in TBI but relative sparing in ADHD. To examine the criterion validity of VMI scores, the authors therefore compared these 2 groups. As anticipated, the TBI group performed significantly worse than the ADHD group, but receiver operator characteristic analysis indicated that VMI scores were poor at discriminating between groups. Nonetheless, convergent validity evidence supported interpretation of VMI scores as measuring perceptual organization in both groups. In particular, principal components analysis indicated that VMI total scores loaded with perceptual organization tests from the Wechsler Intelligence Scale for Children, 3rd ed. (WISC-III; D. Wechsler, 1997), and its highest correlation was with the WISC-III Perceptual Organization Index. Also, the VMI correlated significantly with the Grooved Pegboard test for the group with TBI. These findings suggest that VMI scores are sensitive to visuoconstructional and motor deficits in children with developmental and acquired brain dysfunction.     

Correlations for the Stroop Color and Word Test with measures of reading and language achievement

The present investigation examined the relationships for scores on the Stroop Color and Word Test with measures of reading and language achievement within an adult population. The Stroop Color and Word Test, Nelson-Denny Reading Test, Woodcock-Johnson Psycho-Educational Battery-Revised, and Wide Range Achievement Test-3 were administered to 99 men ranging in age from 18 to 27 years. Pearson product-moment correlations indicated that the Stroop Word task was positively associated with scores on the WRAT-3 Spelling task, the Woodcock-Johnson Basic and Broad Reading tasks, and the Nelson-Denny Rcading Rate and Comprehension tasks. These and other significant relationships were discussed in terms of possible implications regarding the assessment of reading achievement.     

Age-related differences in sequence learning: Findings from two visuo-motor sequence learning tasks

The Serial Reaction Time Task (SRTT) is thought to assess implicit learning, which seems to be preserved with age. However, the reaction time (RT) measures employed on implicit-like tasks might be too unreliable to detect individual differences. We investigated whether RT-based measures mask age effects by comparing the performance of 43 younger and 35 older adults on SRTT and an explicit-like Predictive Sequence Learning Task (PSLT). RT-based measures (difference scores and a ratio) were collected for both tasks, and accuracy was additionally measured for PSLT. We also measured fluid abilities. The RT-difference scores indicated preserved SRTT and PSLT performance with age and did not correlate with fluid abilities, while ratio RT and the accuracy-based measures indicated age-related decline and correlated with fluid abilities. Therefore, RT-difference scores might mask individual differences, which compromises the interpretation of previous studies using SRTT.     

Development of a Brief Cognitive Screen for Mild Cognitive Impairment and Neurocognitive Disorder

Abstract

The purpose of this study was to develop and evaluate a brief cognitive screen for possible Mild Cognitive Impairment (MCI) and other neurocognitive impairment in a sample of general medical patients. Two hundred community-dwelling general medical patients aged 65 or older participated in this study. Age and education corrected scores from the Rey Auditory Verbal Learning Test and Mattis Dementia Rating Scale were used to classify participants into three groups: MCI, neurocognitive disorder, cognitively intact. Groups were then compared on an independent set of measures: the Consortium to Establish a Registry for Alzheimer’s Disease (CERAD) neuropsychological battery, Mini-Mental State Examination, and Clock Drawing Test. The MCI group constituted 9% of the sample, while 10.5% of the sample was classified into the neurocognitive disorder group. The CERAD Verbal Category Fluency and CERAD Word List Memory Test Delayed Recall measures were individually and collectively the most effective in differentiating cognitively intact elders from persons in both the MCI and neurocognitive disorder groups. We conclude that these two brief measures appear to be effective for detecting possible MCI or neurocognitive disorder, thereby facilitating identification of candidates who would benefit from more detailed neuropsychological assessment.     

Impact of comorbid depressive symptoms on neuropsychological performance in obsessive-compulsive disorder.

There is indirect evidence from previous research that several executive disturbances in obsessive-compulsive disorder (OCD) are mediated by comorbid depressive symptoms. For the present study, the authors investigated whether OCD patients with elevated Hamilton Rating Scale for Depression (HRSD) scores would exhibit deficits in tasks sensitive to the medial and dorsolateral frontal cortex as well as other executive tasks. The 36 OCD patients were split along the median according to their HRSD scores and compared with matched control subjects. Patients with high HRSD scores performed significantly worse than control subjects and patients with low HRSD scores on the Wisconsin Card Sorting Test, the Trail-Making Test (TMT, Part B), and the TMT difference score. Moreover, patients with high HRSD scores exhibited deficits on a (creative) verbal fluency task. It is suggested that comorbid depressive symptoms may have artificially inflated some executive deficit scores in previous studies.     

IQ and Scores on the Mini-Mental State Examination (MMSE): Controlling for Effort and Education Among Geriatric Inpatients

ABSTRACT

The Mini-Mental State Examination (MMSE) and the Peabody Picture Vocabulary Test, Third Edition (PPVT-III) were administered to 76 Extended Care Center inpatients of a Veterans Affairs Medical Center, 56 of whom did not carry a diagnosis associated with brain impairment, and 20 of whom had a diagnosis associated with degenerative or cerebrovascular conditions. MMSE and PPVT-III scores, the latter of which estimates verbal IQ, were significantly correlated in both groups, even when controlling for the effects of education. This correlation was attenuated, but remained significant, in the face of varying levels of patient effort. The findings of this study support earlier findings, which also suggest that interpretation of “impaired” performance on the MMSE for those with IQ scores below 90 should be interpreted with caution. Average MMSE scores for Wechsler IQ classifications are provided.     

A PET meta‐analysis of object and spatial mental imagery

Neuroimaging studies have described the functional neuroanatomy of mental imagery. Taken separately, specific studies vary in the nature of the task used and are limited by statistical power and sensitivity. We took advantage of a multistudy PET database of 54 subjects acquired in our laboratory to reveal the neural bases of spatial versus object mental imagery tasks. Our first goal was to evaluate to what extent the activated foci elicited by both object and spatial studies overlap. A second aim was to compare activations elicited by spatial imagery tasks to those elicited by object imagery tasks. We also explored applying regression analyses to the relationships between the scores on the Mental Rotations Test (MRT) and changes in regional cerebral blood flow (rCBF) during spatial and object imagery tasks. This meta‐analysis yielded the following observations: (1) both spatial and object imagery tasks shared a common neural network composed of occipitotemporal (ventral pathway) and occipitoparietal (dorsal pathway) regions and also by a set of frontal regions (related to memory); (2) the superior parietal cortex was more strongly implicated during spatial imagery; (3) object imagery specifically engaged the anterior part of the ventral pathway, including the fusiform, parahippocampal, and hippocampal gyrus; (4) object imagery activated the early visual cortex, whereas spatial imagery induced a deactivation of the early visual cortex; (5) blood flow values in some of the regions noted above were positively correlated with scores on the MRT: the higher the subjects performed on the MRT, the more pronounced the rCBF was in these regions. These results may reconcile some of the apparent discrepancies among previous studies concerning the activation of early visual cortex in mental imagery. They also contribute to a better knowledge of the neural bases of object and spatial mental imagery.     

The 3RT Test: Three reaction time tasks for IBM PC computers

The 3RT Test consists of a simple, a choice, and a conditional reaction time (RT) task. The three tasks involve comparable visual stimuli and require identical manual responses, but they differ in the complexity of cognitive processing required. The nonverbal stimuli convey commonly known meanings. Responses can be made either on the keyboard or on response keys connected to the computer’s serial port. The computer’s internal timer/counter is used for millisecond timing. The test administration program allows flexible setting of the test conditions. The data analysis program provides summary data not only for each RT task as a whole, but also for separate trial types within each task. Summary statistics include measures of variation and central value that are not affected by extreme scores. In addition to laboratory studies with normal adults, the 3RT Test is suitable for life-span developmental studies, cross-cultural comparisons, and other uses in various clinical settings.     

Self,Identity, and the Natural Environment: Exploring Implicit Connections With Nature1

Using the Implicit Association Test (IAT), we examined the tendency for people to associate self with natural or built environments, the malleability of these scores across context, and the relationship between these implicit associations and explicit attitudes about environmental issues. Five studies are reported using a handheld IAT administration in a variety of field contexts. The psychometric properties of the handheld administration were comparable to those obtained with laboratory administration. The cumulative results across the 5 studies suggest that implicit self–nature associations are malleable, but that change requires long‐term or repeated experiences. Findings are interpreted within a model of environmental identity.     

The use of the peabody picture vocabulary test with emotionally disturbed adolescents

The validity and reliability for the Peabody Picture Vocabulary Test (PPVT) was estimated with 52 nonpsychotic emotionally disturbed adolescents. Approximately 6 months after an initial administration of the PPVT and the Peabody Individual Achievement Test (PIAT), all children were retested. Significant increases in PPVT IQ and PIAT reading comprehension scores were found upon readministration. The internal consistency estimate for the initial PPVT administration showed considerable consistency in responding. A modest temporal stability estimate indicated a fair amount of fluctuation in scores over time. Concurrent validity coefficients for the PPVT indicated moderate to dependable relationships with PIAT subtests. Predictive validity estimates for the PPVT suggested moderate relationships with future achievement, accounting for some 26% of the variability in total achievement.     

Neuropsychological problem-solving skills in the elderly

This article describes the performance of a representative sample of 110 participants aged from 65 to 75 years. Participants completed the Trail-Making Test, Tactual Performance Test, and Booklet Category Test. Results confirmed that previously established cutoff scores used to determine impairment are not appropriate for this age group. Significant sex differences were found for the Tactual Performance Test and Booklet Category Test. Mean scores presented in this article provide useful normative standards for the three aforementioned tasks when given to patients aged from 65 to 75 years.     

Copying strategies and memory on the Complex Figure Test in psychiatric patients

We assessed three copying strategies on the Rey-Osterrieth Complex Figure Test among 50 psychiatric patients. The strategies were featural (detail-focused), contextual (framework-focused), and mixed. Reliable classification of each patient's copying strategy showed 7 patients used a featural and 7 patients used a contextual strategy. The remaining 36 used a mixed strategy involving both elements. Analysis indicated that patients who met DSM-III-R criteria for schizophrenia tended to use a mixed strategy. Nonschizophrenic patients also favoured the mixed approach. Moreover, when subjects were divided into groups based on their strategies, there were no differences in copying accuracy. However, the groups differed on immediate and delayed recall of the Complex Figure Test. Patients who adopted a featural strategy on the copy trial had the lowest recall scores. "Process" variables may be important in understanding neurocognitive functioning in schizophrenia; however, there is little evidence that schizophrenic patients use copying strategies consistent with lateralized impairment of brain function.     

Revised norms for the Lollipop Test for children ages 42 to 65 months

Lollipop Test scores were acquired for 1,402 preschoolers in southwestern Indiana. Means and standard deviations for both boys and girls by 6-mo. intervals from the ages of 42 through 65 months showed scores increased significantly across ages, with girls scoring significantly higher than boys in all age groups. Current mean scores are similar to those published in 1988 for boys and slightly higher for girls.     

A Study of low scores in Canadian children and adolescents on the Wechsler Intelligence Scale for Children,Fourth Edition (WISC-IV)

Knowing the prevalence of low neurocognitive scores for the WISC-IV Canadian normative sample (WISC-IV^CDN) is an important supplement for clinical interpretation of test performance. On the WISC-IV^CDN, it is uncommon for children and adolescents to have 4 or more subtest scores or 2 or more Index scores ≤ 9th percentile when all scores on the battery are considered simultaneously. As the level of the child's intelligence increases or the number of years of parental education increases, the prevalence of low scores decreases. These results are consistent with existing studies of the base rates of low scores in children and adolescents on pediatric cognitive batteries, including the WISC-IV American normative sample. Tables provided are ready for clinical use.     

IQ and Scores on the Mini-Mental State Examination (MMSE)

The Mini-Mental State Examination (MMSE) and the Peabody Picture Vocabulary Test-Revised (PPVT-R) were administered to 217 Veterans Affairs (VA) Nursing Home patients, 104 of whom did not carry a diagnosis associated with brain impairment, and 113 who had a diagnosis associated with degenerative or cerebrovascular conditions. MMSE and IQ scores were significantly correlated in both groups, even controlling for the effects of education. It is suggested that although previous normative studies of the MMSE may provide good general clinical guidance, interpretation of “impaired” performance on the MMSE for those with IQ scores below 90 should be approached with caution. Average MMSE scores for Wechsler IQ classifications are provided.