Effect of mindfulness meditation on brain–computer interface performance

Electroencephalogram based brain–computer interfaces (BCIs) enable stroke and motor neuron disease patients to communicate and control devices. Mindfulness meditation has been claimed to enhance metacognitive regulation. The current study explores whether mindfulness meditation training can thus improve the performance of BCI users. To eliminate the possibility of expectation of improvement influencing the results, we introduced a music training condition. A norming study found that both meditation and music interventions elicited clear expectations for improvement on the BCI task, with the strength of expectation being closely matched. In the main 12 week intervention study, seventy-six healthy volunteers were randomly assigned to three groups: a meditation training group; a music training group; and a no treatment control group. The mindfulness meditation training group obtained a significantly higher BCI accuracy compared to both the music training and no-treatment control groups after the intervention, indicating effects of meditation above and beyond expectancy effects.     

Ideomotor silence: the case of complete paralysis and brain–computer interfaces (BCI)

The paper presents some speculations on the loss of voluntary responses and operant learning in long-term paralysis in human patients and curarized rats. Based on a reformulation of the ideomotor thinking hypothesis already described in the 19th century, we present evidence that instrumentally learned responses and intentional cognitive processes extinguish as a consequence of long-term complete paralysis in patients with amyotrophic lateral sclerosis (ALS). Preliminary data collected with ALS patients during extended and complete paralysis suggest semantic classical conditioning of brain activity as the only remaining communication possibility in those states.     

Learning in the brain–computer interface: insights about degrees of freedom and degeneracy from a landscape model of motor learning

In this paper, we examine the role of degrees of freedom and their degeneracy in learning in the brain–computer interface paradigm. Though the traditional notion of degrees of freedom in motor learning gave emphasis to muscle and joint activity, the broader concept of dimensions of behavior is relevant to brain–computer interface learning where there is no muscle activity. The role of degeneracy in the dimensions of brain activity is proposed to enhance learning through robustness to stability loss and adaptability in the search for new stable states. Principles for the application of augmented information for learning to coordinate and control the degenerate degrees of freedom in the brain–computer interface are outlined.     

Mind control? Creating illusory intentions through a phony brain–computer interface

Can one be fooled into believing that one intended an action that one in fact did not intend? Past experimental paradigms have demonstrated that participants, when provided with false perceptual feedback about their actions, can be fooled into misperceiving the nature of their intended motor act. However, because veridical proprioceptive/perceptual feedback limits the extent to which participants can be fooled, few studies have been able to answer our question and induce the illusion to intend. In a novel paradigm addressing this question, participants were instructed to move a line on the computer screen by use of a phony brain–computer interface. Line movements were actually controlled by computer program. Demonstrating the illusion to intend, participants reported more intentions to move the line when it moved frequently than when it moved infrequently. Consistent with ideomotor theory, the finding illuminates the intimate liaisons among ideomotor processing, the sense of agency, and action production.     

Use of functional magnetic resonance imaging to assess cognition and consciousness in severe Guillain-Barré syndrome

ObjectiveFunctional neuroimaging may provide a viable means of assessment and communication in patients with Guillain-Barré Syndrome (GBS) mimicking the complete locked-in state. Functional neuroimaging has been used to assess residual cognitive function and has allowed for binary communication with other behaviourally non-responsive patients, such as those diagnosed with unresponsive wakefulness syndrome. We evaluated the potential application of functional neuroimaging using a clinical-grade scanner to determine if individuals with severe GBS retained auditory function, command following, and communication.MethodsFourteen healthy participants and two GBS patients were asked to perform motor imagery and spatial navigation imagery tasks while being scanned using functional magnetic resonance imaging. The GBS patients were also asked to perform additional functional neuroimaging scans to attempt communication.ResultsThe motor imagery and spatial navigation task elicited significant activation in appropriate regions of interest for both GBS patients, indicating intact command following. Both patients were able to use the imagery technique to communicate in some instances. Patient 1 was able to use one of four communication tasks to answer a question correctly. Patient 2 was able to use three of seven communication tasks. However, two questions were incorrectly answered while a third was non-verifiable.ConclusionsGBS patients can respond using mental imagery and these responses can be detected using functional neuroimaging. Furthermore, these patients may also be able to use mental imagery to provide answers to ‘yes’ or ‘no’ questions in some instances. We argue that the most appropriate use of neuroimaging-based communication in these patients is to allow them to communicate wishes or preferences and assent to previously expressed decisions, rather than to facilitate decision-making.     

Age-related changes in brain–behaviour relationships: Evidence from event-related functional MRI studies

A fundamental aim of studies in neurocognitive ageing is to understand age-related changes in brain–behaviour relationships. Neuroimaging techniques such as positron emission tomography (PET) and functional magnetic resonance imaging (fMRI) can be used for observation of these age-related changes only if the assumption of age-equivalent relations between neural activity and haemodynamic activity is valid. In one study, we characterised age-related differences in the coupling of the haemodynamic response to neural activity and found greater voxel-wise noise in older than in younger adults, but age-equivalent signal magnitude. These results suggested that alternative techniques may be necessary for analysing age-related differences in neuroimaging data. In a second study, we utilised one alternative method for comparing fMRI activation between younger and older adults performing a working memory (WM) task. Across three experiments, the results suggested that age-related functional changes in fMRI activation can be isolated to dorsolateral prefrontal cortex (PFC) during memory retrieval. These results suggest a plausible model for WM decline with normal ageing. In a third study we propose and test a model of age-related PFC dysfunction that may account for these and other age-related differences in cognitive performance.     

Précis of The brain and emotion

The topics treated in The brain and emotion include the definition, nature, and functions of emotion (Ch. 3); the neural bases of emotion (Ch. 4); reward, punishment, and emotion in brain design (Ch. 10); a theory of consciousness and its application to understanding emotion and pleasure (Ch. 9); and neural networks and emotion-related learning (Appendix). The approach is that emotions can be considered as states elicited by reinforcers (rewards and punishers). This approach helps with understanding the functions of emotion, with classifying different emotions, and in understanding what information-processing systems in the brain are involved in emotion, and how they are involved. The hypothesis is developed that brains are designed around reward- and punishment-evaluation systems, because this is the way that genes can build a complex system that will produce appropriate but flexible behavior to increase fitness (Ch. 10). By specifying goals rather than particular behavioral patterns of responses, genes leave much more open the possible behavioral strategies that might be required to increase fitness. The importance of reward and punishment systems in brain design also provides a basis for understanding the brain mechanisms of motivation, as described in Chapters 2 for appetite and feeding, 5 for brain-stimulation reward, 6 for addiction, 7 for thirst, and 8 for sexual behavior.     

Responsiveness and functional connectivity of the scene-sensitive retrosplenial complex in 7–11-year-old children

Brain imaging studies have identified two cortical areas, the parahippocampal place area (PPA) and the retrosplenial complex (RSC), that respond preferentially to the viewing of scenes. Contrary to the PPA, little is known about the functional maturation and cognitive control of the RSC. Here we used functional magnetic resonance imaging and tasks that required attention to scene (or face) images and suppression of face (or scene) images, respectively, to investigate task-dependent modulation of activity in the RSC and whole-brain functional connectivity (FC) of this area in 7–11-year-old children and young adults. We compared responsiveness of the RSC with that of the PPA. The RSC was selectively activated by scene images in both groups, albeit less than the PPA. Children modulated activity between the tasks similarly in the RSC and PPA, and to the same extent as adults in PPA, whereas adults modulated activity in the RSC less than in PPA. In children, the whole brain FC of the RSC was stronger in the Sf than Fs task between the left RSC and right fusiform gyrus. The between groups comparison suggested stronger FC in children than adults in the Sf task between the right RSC and the left inferior parietal lobule and intraparietal sulcus. Together the results suggest that the function of the RSC and the related networks undergo dynamic changes over the development from 7–11-year-old children to adulthood.     

Direct brain communication: neuroelectric and metabolic approaches at Tübingen

The brain–computer interface (BCI) provides users with the possibility of sending messages and commands to the external world without using their muscles, thus enabling communication to occur independent of movement. Such a possibility is of utmost importance for paralyzed patients who may otherwise lose their ability to communicate. Enhanced methodology and the development of faster computers have substantially improved applications and offer new possibilities in this field. To date, there have been over 20 BCI research groups working on different approaches. In this paper, we review our studies of BCI based on electric and metabolic activity of the brain.     

Collaborative mother–toddler communication and theory of mind development at age 4

Focusing on social pragmatics, this longitudinal study investigated the contribution of mother–toddler collaborative communication to theory of mind (ToM) development at age 4. At age 2½, 78 toddlers (42 boys) and their mothers were observed during pretend play. At age 4, children were tested using 4 false belief understanding tasks. Both mothers and toddlers engaged in more collaborative (inform, guide/request, and support/confirm) than non-collaborative communication acts. Other-focused collaborative acts of support/confirm by mothers and toddlers predicted children's false belief understanding, even after controlling for 5 covariates. In addition, as active agents in their own ToM development, the contribution of toddlers' collaborative acts to false belief understanding was independent of their mother's. Finally, the way toddlers and their mothers co-constructed their communication mattered. Only when toddlers engaged in high levels of collaborative acts, the mothers' high levels of collaborative acts demonstrated a positive effect on children's ToM development. The applied implications of these findings are discussed.     

Dog–human social relationship: representation of human face familiarity and emotions in the dog brain

Animal Cognition - This study investigated the behavioral and neural indices of detecting facial familiarity and facial emotions in human faces by dogs. Awake canine fMRI was used to evaluate...     

Dear Santa,do you have my brand? A study of the brand requests,awareness and request styles at Christmas time

This study examines brand awareness (preferences) and request styles (communication approaches) at Christmas of Australian children and adults. The study is founded in the growing Santa Claus literature that has examined various issues related to gift giving and request behaviour at Christmas time. The study is based on the content analysis of 422 letters written by children to Santa Claus. The results indicate that children are brand‐orientated in their request behaviour, adopt fairly meaningful request strategies and use visual imagery ie graphics in their communication strategies in their attempts to secure their requested gifts and specific brands. Copyright © 2002 Henry Stewart Publications Ltd.     

Composition of brain oscillations and their functions in the maintenance of auditory,visual and audio–visual speech percepts: an exploratory study

In the present exploratory study based on 7 subjects, we examined the composition of magnetoencephalographic (MEG) brain oscillations induced by the presentation of an auditory, visual, and audio-visual stimulus (a talking face) using an oddball paradigm. The composition of brain oscillations were assessed here by analyzing the probability-classification of short-term MEG spectral patterns. The probability index for particular brain oscillations being elicited was dependent on the type and the modality of the sensory percept. The maintenance of the integrated audio-visual percept was accompanied by the unique composition of distributed brain oscillations typical of auditory and visual modality, and the contribution of brain oscillations characteristic for visual modality was dominant. Oscillations around 20 Hz were characteristic for the maintenance of integrated audio-visual percept. Identifying the actual composition of brain oscillations allowed us (1) to distinguish two subjectively/consciously identical mental percepts, and (2) to characterize the types of brain functions involved in the maintenance of the multi-sensory percept.     

Risk‐taking and the adolescent brain: who is at risk?

Relative to other ages, adolescence is described as a period of increased impulsive and risk-taking behavior that can lead to fatal outcomes (suicide, substance abuse, HIV, accidents, etc.). This study was designed to examine neural correlates of risk-taking behavior in adolescents, relative to children and adults, in order to predict who may be at greatest risk. Activity in reward-related neural circuitry in anticipation of a large monetary reward was measured with functional magnetic resonance imaging, and anonymous self-report ratings of risky behavior, anticipation of risk and impulsivity were acquired in individuals between the ages of 7 and 29 years. There was a positive association between accumbens activity and the likelihood of engaging in risky behavior across development. This activity also varied as a function of individuals' ratings of anticipated positive or negative consequences of such behavior. Impulsivity ratings were not associated with accumbens activity, but rather with age. These findings suggest that during adolescence, some individuals may be especially prone to engage in risky behaviors due to developmental changes in concert with variability in a given individual's predisposition to engage in risky behavior, rather than to simple changes in impulsivity.