Neuropsychiatric and neuropathologic findings in an adult case of cri-du-chat syndrome (Lejeune syndrome, crying cat syndrome)

It is reported on a mental retarded female, observed from 3-33 years of age, which demonstrated even in adulthood with long lasting shrill crying the clinical leading symptom of Lejeune syndrome and further typical symptoms with inhibition of physical maturation, important delayed motoric and mental development, microcephaly resp. characteristic craniofacial dysmorphia, anomalies of extremities, muscular hypotonia and susceptibility to infection. Psychically there were a striking affective instability and irritability, neuropathologically pachygyria and multiple cortical heterotopias.     

Influence of typical size of objects in a categorization task]

This study explores the influence of typical size during a categorization task. The specificity of this experimental work is based on the homogeneity of the graphic stimuli size. We have created a typical size standard of our stimuli, that concerns the real size of the objects represented by the drawings of homogeneous sizes. Then, a priming experiment was performed in which the prime and target drawings had two types of relations: a typical size, and a categorial. The participants are na?ve as to the typical size relation between prime and target. The results show a positive priming effect of the typical size but not of the category. The results are discussed in term of theoretical approach developed by Barsalou and his colleagues (1999, 2003). In this theoretical framework, the typical size can be considered as a perceptual knowledge. In that way, we propose that participants could automatically simulate the typical size as soon as they perceived the drawings of objects with homegenous sizes.     

What is Absolute Undecidability?†

It is often alleged that, unlike typical axioms of mathematics, the Continuum Hypothesis (CH) is indeterminate. This position is normally defended on the ground that the CH is undecidable in a way that typical axioms are not. Call this kind of undecidability “absolute undecidability”. In this paper, I seek to understand what absolute undecidability could be such that one might hope to establish that (a) CH is absolutely undecidable, (b) typical axioms are not absolutely undecidable, and (c) if a mathematical hypothesis is absolutely undecidable, then it is indeterminate. I shall argue that on no understanding of absolute undecidability could one hope to establish all of (a)–(c). However, I will identify one understanding of absolute undecidability on which one might hope to establish both (a) and (c) to the exclusion of (b). This suggests that a new style of mathematical antirealism deserves attention—one that does not depend on familiar epistemological or ontological concerns. The key idea behind this view is that typical mathematical hypotheses are indeterminate because they are relevantly similar to CH.     

“The other”: Persistent beliefs regarding HIV risk in South Africa

This study explored stereotype constructions people may impute on to others in the context of a contagious disease epidemic. Participants were 30 undergraduate students from a large university in Johannesburg, South Africa. They completed the open-ended Build-A-Character Questionnaire, which described the “typical” person in South Africa who they currently believed to be at particular risk of HIV infection. The data were thematically analysed and interpreted. Seven themes resulted, based on the stereotyping of marginalised groups in South Africa considered as being at higher risk for HIV due to historical disadvantage: blacks, women, and the poor. A social cognitive framework explains these stereotypes as they apply to perceived out-groups, and they carry risk to undermine public health interventions regarding the HIV pandemic in South Africa across population segments.     

Typicality effects on memory for voice: Implications for earwitness testimony

The effects of voice typicality on voice recognition were examined. In an incidental task, participants were presented with consonant‐vowel‐consonant stimuli (with varying vowels) spoken by voices rated as high‐typical or low‐typical. One week later, they were brought back for a surprise voice recognition test where the target voice was presented along with low‐typical and high‐typical voice distracters. The results indicated that voice misidentifications occur, with many errors due to confusions of high‐typical voice targets with high‐typical target voices. The results show that voice typicality affects voice recognition accuracy and is an important factor to be considered in real‐life earwitness testimony situations. Copyright © 2009 John Wiley & Sons, Ltd.     

Typicality effects in face and object perception: further evidence for the attractor field model

In a previous study, it was shown that a 50/50 morph of a typical and an atypical parent face was perceived to be more similar to the atypical parent face than to the typical parent face (Tanaka, Giles, Kremen, & Simon, 1998). Experiments 1 and 2 examine face typicality effects in a same/different discrimination task in which typical or atypical faces and their 80%, 70%, 60%, and 50% morphs were presented sequentially (Experiment 1) or simultaneously (Experiment 2). The main finding was that in both modes of presentation, atypical morphs were more poorly discriminated than their corresponding typical morphs. In Experiment 3, typicality effects were extended to the perception of nonface objects; in this instance, it was found that 50/50 morphs of birds and cars were judged to be more similar to their atypical parents than to their typical parents. These results are consistent with an attractor field model, in which it is proposed that the perception of a face or object stimulus depends not only on its fit to an underlying representation, but also on the representation's location in the similarity space.     

EXPLORING RELATIONS BETWEEN TYPICAL AND MAXIMUM PERFORMANCE RATINGS AND THE FIVE FACTOR MODEL OF PERSONALITY

The study tests the distinction between typical and maximum criteria with ratings of transformational leadership performance, and examines whether the criterion-related validities of the five factor model differ for the two types of criteria. Using an East Asian military sample ( n = 1,259) where multiple ratings of typical and maximum performance were obtained from different sources, we used structural equation modeling to test the typical/maximum performance distinction. Results found that typical and maximum performance are different latent constructs and that this distinction is present even after considering rating method factors (i.e., rater source, time). The importance of this distinction is shown by the fact that validities for the personality constructs were not equally predictive of both criteria: Openness was most predictive of maximum performance, Neuroticism was most predictive of typical performance, and Extroversion was predictive of both. By distinguishing typical from maximum performance constructs, relationships between personality and transformational leadership were found to be stronger than previous research suggested.     

Infection markers and early signs of neonatal encephalopathy in the term infant

Recent evidence points to an association between intrauterine infection and cerebral palsy (CP) in the preterm as well as the term infant. The mechanisms that link these two conditions are unclear. Chorioamnionitis is a common clinical problem complicating 5-10% of pregnancies, whereas the incidence of CP attributed to intrapartum asphyxia is rare. Chorioamnionitis may result in brain injury as a result of interruption of placental blood flow (asphyxia), or via fever and/ or the cytokine release associated with infection. This review will attempt to establish the link between perinatal infection and brain damage in term infants. The characteristics of the perinatal inflammatory response, the potential mechanisms of brain injury associated with infection, and the clinical characteristics of neonatal encephalopathy will be discussed.     

Differences in attentional involvement underlying the perception of distinctive and typical faces

Differences in human faces can be evaluated along a continuum that ranges from 'distinctive' to 'typical.' We examined processing differences between distinctive and typical faces by two attentional tasks that induce attentional blink (AB). Given that AB is believed to reflect temporal or capacity limits of attention, stimuli that survive AB are believed to be associated with greater processing efficiency. In a change-detection task, participants were required to detect changes in the two pairs of faces that were presented in rapid succession. Changes involving the distinctive face of a pair were more likely to be detected than those involving a typical face. In a face-identification task, distinctive faces embedded in a rapid serial visual presentation (RSVP) stream were identified with a greater accuracy than typical faces. Together, our results suggest that distinctive faces are associated with greater processing efficiency and may be explained in terms of perceptual salience, a stimulus dimension known to attract attention.     

Perceptual impulsions and unfamiliar solids: Evidence from a drawing task

Previous work (Dziurawiec & Derȩgowski, 1992) has shown that children's distorted drawings of animal models may be explained by the child's tendency to depict typical contours, the outlines of the surfaces which undergo pronounced change. The present paper investigates whether the typical contours notion can be extended to purely geometric solids. Results from a drawing task by children aged nine and eleven years, using unfamiliar models of varying complexity, indicate that the tendency to draw in perspective increases with the increase in figure complexity for both age groups, but younger children show a greater reliance on typical contours than older children. Recasting the data from previous drawing experiments (Bartel, 1928/1958; Cox, 1986) further confirms the utility of the typical contours approach. Finally, the advantages of such an approach over that of canonicity (cf. Palmer, Rosch & Chase, 1981) for the representation of solids are elaborated.     

Simplicity and Typical Rank Results for Three-Way Arrays

Matrices can be diagonalized by singular vectors or, when they are symmetric, by eigenvectors. Pairs of square matrices often admit simultaneous diagonalization, and always admit block wise simultaneous diagonalization. Generalizing these possibilities to more than two (non-square) matrices leads to methods of simplifying three-way arrays by nonsingular transformations. Such transformations have direct applications in Tucker PCA for three-way arrays, where transforming the core array to simplicity is allowed without loss of fit. Simplifying arrays also facilitates the study of array rank. The typical rank of a three-way array is the smallest number of rank-one arrays that have the array as their sum, when the array is generated by random sampling from a continuous distribution. In some applications, the core array of Tucker PCA is constrained to have a vast majority of zero elements. Both simplicity and typical rank results can be applied to distinguish constrained Tucker PCA models from tautologies. An update of typical rank results over the real number field is given in the form of two tables.     

Ethical Considerations in Psychotherapy Effectiveness Research: Choosing the Comparison Group

The primary purpose behind effectiveness research is to determine whether a treatment with demonstrated efficacy has utility when administered to the general population. The main questions these studies are meant to answer are these: Can the typical patient respond to treatment? Is the treatment acceptable to the typical patient? Can the treatment be administered safely and in its entirety in the typical treatment setting? Is the treatment under study significantly better than the community standard of care both from a cost and outcome perspective? Answering these questions is meant to provide sufficient information to providers and policymakers so that effective interventions can be adopted and become the new community standard.

For this research to make a meaningful impact on a provider and policymaker's decision to change the status quo, study interventions should be compared to the existing community standard of treatment, often referred to as treatment as usual (TAU). From an ethical perspective, this decision may not always be the safest choice. In some populations, TAU may mean no treatment at all, and in others TAU may be worse than withholding treatment. The effectiveness researcher is then caught between the pull to do no harm and the need for research to have an impact on change. The purpose of this article is to highlight certain conditions when TAU is ethically acceptable and to discuss alternatives when TAU may be an unethical treatment condition. For purposes of precision, we focus exclusively on psychotherapy effectiveness research rather than system-intervention research or medication-intervention research.     

Ethical considerations in psychotherapy effectiveness research: choosing the comparison group

The primary purpose behind effectiveness research is to determine whether a treatment with demonstrated efficacy has utility when administered to the general population. The main questions these studies are meant to answer are these: Can the typical patient respond to treatment? Is the treatment acceptable to the typical patient? Can the treatment be administered safely and in its entirety in the typical treatment setting? Is the treatment under study significantly better than the community standard of care both from and a cost and outcome perspective? Answering these questions is meant to provide sufficient information to providers and policymakers so that effective interventions can be adopted and become the new community standard. For this research to make a meaningful impact on a provider and policymaker's decision to change the status quo, study interventions should be compared to the existing community standard of treatment, often referred to as treatment as usual (TAU). From an ethical perspective, this decision may not always be the safest choice. In some populations, TAU may mean no treatment at all, and in others TAU may be worse than withholding treatment. The effectiveness researcher is then caught between the pull to do no harm and the need for research to have an impact on change. The purpose of this article is to highlight certain conditions when TAU is ethically acceptable and to discuss alternatives when TAU may be an unethical treatment condition. For purposes of precision, we focus exclusively on psychotherapy effectiveness research rather than system-intervention research or medication-intervention research.     

To transfer or not to transfer? Investigating the combined effects of trainee characteristics, team leader support, and team climate

Eighty pilots participated in a study of variables influencing the transfer process. Posttraining performance was assessed in a flight simulation under 1 of 2 conditions. Those in the maximum performance condition were made aware of the skill to be assessed and the fact that their teammates were confederates, whereas those in the typical performance condition were not. The results indicated that (a) simulator ratings correlated with a measure of transfer to the cockpit for those in the typical condition only; (b) team leader support, manipulated in a pretask brief, moderated the disparity between maximum and typical performance; (c) team climate mediated the impact of support on performance in the typical condition; (d) those with a stronger predisposition toward the trained skill viewed their climate as more supportive; and (e) perceptions of team climate were better predictors of performance for those with a more external locus of control.     

Developmental course of the temporal relationship between gaze direction and vocal production in typical and Down's syndrome infants

This study was aimed at examining the temporal relationship between gaze and vocal production behaviour among typically developing infants, infants with Down's syndrome, and their mothers. If gaze–voice timing behaviour is an organizing principle of communicative interaction in typical population, then studying it should provide insight into how children with Down's syndrome and their mothers use this temporal relationship to structure their exchanges. Forty-four mother–infant dyads (22 dyads with a Down's syndrome child and 22 with a typical child) were observed. The developmental course of timing pattern was not different between DS and typically developing infants from 4 to 19 months (DA). Insofar as the timing patterns differed between DS and typical infants at 20 months, this could be explained by their differing level of language acquisition. With the use of language, the timing patterns will reappear equal in the both populations. Results suggest that (i) the children's behaviours could be partially explained by the behaviours of their mothers. The mother–child dyad would be the mould that shapes the child's future sociolinguistic skills, and (ii) for the two populations, the timing-pattern changes could be explained by the emergence of language.     

性别刻板印象表征的形式及神经基础

本实验采用ERP技术,考察性别刻板印象的表征。结果发现,无论启动是上位范畴、子范畴、典型样例还是反例,被试对于刻板印象不一致的表征比一致的表征均诱发了波幅更大的N400,反应时更长。并且,被试对于性别刻板印象的表征存在层级差异。研究结果表明：（1）性别刻板印象的表征存在层级结构。（2）语义启动下,性别刻板印象违背诱发N400效应。（3）性别刻板印象表征存在自上而下的由大脑额叶进行的语义分类加工。     

Acquiring an understanding of design: evidence from children's insight problem solving

The human ability to make tools and use them to solve problems may not be zoologically unique, but it is certainly extraordinary. Yet little is known about the conceptual machinery that makes humans so competent at making and using tools. Do adults and children have concepts specialized for understanding human-made artifacts? If so, are these concepts deployed in attempts to solve novel problems? Here we present new data, derived from problem-solving experiments, which support the following. (i) The structure of the child's concept of artifact function changes profoundly between ages 5 and 7. At age 5, the child's conceptual machinery defines the function of an artifact as any goal a user might have; by age 7, its function is defined by the artifact's typical or intended use. (ii) This conceptual shift has a striking effect on problem-solving performance, i.e. the child's concept of artifact function appears to be deployed in problem solving. (iii) This effect on problem solving is not caused by differences in the amount of knowledge that children have about the typical use of a particular tool; it is mediated by the structure of the child's artifact concept (which organizes and deploys the child's knowledge). In two studies, children between 5 and 7 years of age were matched for their knowledge of what a particular artifact "is for", and then given a problem that can only be solved if that tool is used for an atypical purpose. All children performed well in a baseline condition. But when they were primed by a demonstration of the artifact's typical function, 5-year-old children solved the problem much faster than 6-7-year-old children. Because all children knew what the tools were for, differences in knowledge alone cannot explain the results. We argue that the older children were slower to solve the problem when the typical function was primed because (i) their artifact concept plays a role in problem solving, and (ii) intended purpose is central to their concept of artifact function, but not to that of the younger children.     

Le risque médico-judiciaire des infections nosocomiales

These last years in France, the term ‘nosocomial infection’ has been replaced by ‘health-care associated infection’, which has a much broader definition. In all cases, the plausibility of the association between infection and the care provided deserved to be rigorously analyzed. To qualify an infection as nosocomial, the expert witness must at the judge's request determine that infection actually occurred within the health facility and is linked to health care. French Public Health Code as well the most recent jurisprudence give currently a rather close definition of nosocomial infection. The principle of faultness liability in the field of nosocomial infection has been enshrined in the law of March 4^th 2002, the most severe situations (death; permanent functional deficit > 25 percent) being compensated by ONIAM, the French national office of compensation for nosocomial infection.     

Values Define Fields: The Intentional Dynamics of Driving,Carrying, Leading,Negotiating, and Conversing

Coss (1991a) found that squirrels from populations that differed in their historical exposure to snakes reacted in a manner similar to that of squirrels sympatric with snakes when exposed to one; lab-reared pups also showed some typical reactions to a snake. Coss concluded that the squirrels possessed a genetic relic of the pattern of behavior typical of the common progenitor at a time when snakes exerted selection pressure on squirrel evolution. It is argued here that this concept of behavioral relics is suspect and should be employed with caution. The concept is difficult to apply rigorously, and the philosophy of the concept is diametrically opposed to the animal-environment mutualism espoused by ecological psycholo- gists. Three more parsimonious explanations for the phenomena reported in Coss (199 1 a) are suggested.