神经肌肉下意识前馈与反馈控制的知觉线索效应

为研究视觉和时间知觉线索对突发外部姿势干扰下中枢神经系统对动作肌肉和姿势肌肉预期姿势调节(APAs)和补偿姿势调节(CPAs)的影响, 本研究被试分别在视觉和时间线索引导下完成经典落球试验, 同步采集右侧动作肌肉肱二头肌和姿势肌肉腰部竖脊肌和腰部多裂肌的sEMG信号, 计算被检肌肉APAs发生率、预激活时间和CPAs反应强度。结果发现, 视觉线索可以引发动作肌肉和姿势肌肉APAs发生率明显增加, 预激活时间明显提前, 以及动作肌肉CPAs反应强度明显减小; 而时间线索主要引发动作肌肉预激活提前, 对姿势肌肉APAs和CPAs无明显影响。该结果表明, 视觉和时间引导线索对突发外部姿势干扰条件下人体姿势肌肉和动作肌肉的中枢运动控制具有不同的作用。视觉引导线索能够明显增加姿势肌肉和动作肌肉预激活发生率和提早预激活时间, 表现出明显的“视觉线索预激活优势现象”; 而时间引导线索主要引发动作肌肉预激活提前, 对姿势肌肉APAs和CPAs无明显影响。     

姿势干扰强度的心理预期效应

本研究基于经典快速举臂试验与落球试验范式, 采用表面肌电信号分析技术, 研究内、外姿势干扰强度的心理预期对腰部姿势肌肉和上肢动作肌肉预期姿势调节(APAs)和补偿姿势调节(CPAs)的影响, 探讨中枢神经系统(CNS)对内、外姿势干扰的控制策略。20名健康受试者先后完成不同负荷强度的快速举臂试验和落球试验, 同步采集腰部竖脊肌、腰部多裂肌和上肢肱二头肌的表面肌电信号, 计算肌肉预激活时间和APAs与CPAs积分肌电值, 观察内、外姿势干扰强度的心理预期对中枢APAs和CPAs控制机制的影响。结果显示内部姿势干扰条件下, 干扰强度的心理预期对腰部多裂肌、腰部竖脊肌和上肢肱二头肌的APAs强度有显著影响, 而对预激活时间和CPAs强度无显著影响; 外部姿势干扰条件下, 干扰强度的心理预期对腰部多裂肌、腰部竖脊肌和肱二头肌的APAs强度有显著影响, 对肱二头肌和腰部多裂肌预激活时间有显著影响, 而对CPAs强度无显著影响。突发可预期姿势干扰条件下姿势的快速反应是一个由CNS主导的神经肌肉运动控制过程。受姿势干扰强度心理预期的影响, CNS对内、外突发姿势干扰条件下腰部姿势肌肉的活动采取了不同的控制策略。在内部姿势干扰条件下, 干扰刺激发生时间明确, CNS主要通过对APAs强度的调节来实现姿势肌肉的优化控制; 而在外部姿势干扰条件下, 干扰刺激时间不明确, CNS则通过对局部稳定肌APAs预激活时间以及局部稳定肌和整体稳定肌APAs强度的双重调节实现姿势肌肉的优化控制。干扰强度的心理预期对姿势肌肉APAs和CPAs的作用表明, 心理预期效应主要源自于CNS对局部和整体稳定肌APAs控制机制的调制。     

Anticipatory postural adjustments during a Fitts’ task: Comparing young versus older adults and the effects of different foci of attention

Anticipatory postural adjustments (APAs) are an integral part of standing balance. Previous research with balance control has shown that adopting an external focus of attention, compared to an internal focus of attention, yields better performance during motor skills. Despite the importance of APAs, especially among older adults, and the potential benefits of adopting an external focus of attention, studies investigating methods for improving APAs are limited. The aim of this study was to compare behavioral, kinematic and APAs measures while adopting different foci of attention among young and older adults when performing a lower extremity Fitts’ task. Ten young adults (mean age 24 years ± 4.37) and ten older adults (mean age 75 years ± 5.85) performed a lower-extremity reaching task (Fitts’ task) while adopting an external focus (focus on target) and an internal focus (focus on limb) in a within-subject design. A motion capture system was used to record participants’ movement data. Custom software derived movement time (MT), peak velocity (PV), time to peak velocity (ttPV) and variability at target (SD_T). Electromyography (EMG) was used to determine APAs onset and magnitude. The findings showed that an external focus of attention led to significantly shorter MT, higher PV, shorter ttPV and more accuracy when reaching the target (SD_T) for both age groups. Also, EMG results showed that, with an external focus, APAs onset occurred earlier and APAs magnitude was more efficient. As predicted by Fitts’ Law, participants spent more time executing movements to targets with higher indices of difficulty. Older adults compared to young adults were more adversely affected by the increase of difficulty of the Fitts’ task, specifically, on measures of APAs. In conclusion, adopting an external focus of attention led to better overall movement performance when performing a lower extremity Fitts’ task. The task used in the present study can distinguish between APAs for older and young adults. We recommend that future studies expand on our findings in order to establish a performance-based objective measure of APAs to assess clinical interventions for postural control impairment.     

Balancing cognitive control: How observed movements influence motor performance in a task with balance constraints

We investigated the influence of observed movements on executed movements in a task requiring lifting one foot from the floor while maintaining whole-body balance. Sixteen young participants (20–30 years) performed foot lift movements, which were either cued symbolically by a letter (L/R, indicating to lift the left/right foot) or by a short movie showing a foot lift movement. In the symbol cue condition, stimuli from the movie cue condition were used as distractors, and vice versa. Anticipatory postural adjustments (APAs) and actual foot lifts were recorded using force plates and optical motion capture. Foot lift responses were generally faster in response to the movie compared to the symbol cue condition. Moreover, incongruent movement distractors interfered with performance in the symbol cue condition, as shown by longer response times and increased number of APAs. Latencies of the first (potentially wrong) APA in a trial were shorter for movie compared to symbol cues but were not affected by cue-distractor congruency. Amplitude of the first APA was smaller when it was followed by additional APAs compared to trials with a single APA. Our results show that automatic imitation tendencies are integrated with postural control in a task with balance constraints. Analysis of the number, timing and amplitude of APAs indicates that conflicts between intended and observed movements are not resolved at a purely cognitive level but directly influence overt motor performance, emphasizing the intimate link between perception, cognition and action.     

Coordination of rapid stepping with arm pointing: anticipatory changes and step adaptation

The present study explored whether rapid stepping is influenced by the coordination of an arm pointing task. Nine participants were instructed to (a) point the index finger of the dominant arm towards a target from the standing posture, (b) initiate a rapid forward step with the contralateral leg, and (c) synchronize stepping and pointing (combined task). Force plate and ankle muscle electromyography (EMG) recordings were contrasted between (b) and (c). In the combined task, the arm acceleration trace most often peaked around foot-off, coinciding with a 15% increase in the forward acceleration of the center of gravity (CoG). Backward displacement of the center of foot pressure at foot-off, duration of anticipatory postural adjustments (APAs) and ankle muscle EMG activity remained unchanged. In contrast, durations of swing phase and whole step were reduced and step length was smaller in the combined task. A reduction in the swing phase was correlated with an increased CoG forward acceleration at foot-off. Changes in the biomechanics of step initiation during the combined task might be ascribed to the postural dynamics elicited by arm pointing, and not to a modulation of the step APAs programming.     

Hierarchical control in redundant and non-redundant postural tasks

Prior studies of postural coordination have shown inconsistencies between hip-ankle coordination in redundant and non-redundant coordination tasks as well as predictions of the HKB model. These inconsistencies were investigated by testing the hypothesis that there are different hierarchical control structures for redundant (multiple potential task solutions) and non-redundant (a single task solution) coordination tasks (Bernstein, 1996). The transfer between a non-redundant postural tracking task and a redundant scanning task consisting of 16 hip-ankle relative phase patterns from 0° to 337.5° was investigated. The results showed that the transfer between the tasks was transitory, negative and occurred only from the non-redundant to the redundant task. This finding supports the hypothesis that inconsistencies between redundant and non-redundant coordination dynamics may be due to a hierarchical relation between control structures for the performance of these types of tasks.     

Effects of varying load conditions on the organization of postural adjustments during voluntary arm flexion

One purpose of the experiments reported here was to further clarify the effect of varying loads on postural adjustments. Another was to reevaluate whether or not the timing of electromyographic (EMG) activity in the postural muscle is preprogrammed. To accomplish these goals, we compared the effect of the presence or absence of prior knowledge of a load on the timing of EMG activity in the postural muscle (biceps femoris [BF]) with that in the focal muscle (anterior deltoid [AD]). Although the sequence of EMG activation was similar under conditions with and without a load, the timing of postural EMG activities (BFi, ipsilateral BF; BFc, contralateral BF) in associated postural adjustments was dependent on the force of arm movement, and the latencies of postural EMG activities (BFi-BFc) were dependent on the speed of arm movement. This indicates that EMG changes in the upper (focal muscle) and lower limbs (postural muscle) were triggered by different motor programs. Moreover, similar EMG activities were observed in postural muscles when the subject had advance knowledge of the presence or the absence of a load. Thus, this suggests that BFi may be centrally preprogrammed (anticipatory regulation) and BFc may be feedback regulated. Furthermore, environmental information may be a critical source of influence on those postural responses.     

Effects of Varying Load Conditions on the Organization of Postural Adjustments during Voluntary Arm Flexion

One purpose of the experiments reported here was to further clarify the effect of varying loads on postural adjustments. Another was to reevaluate whether or not the timing of electromyographic (EMG) activity in the postural muscle is preprogrammed. To accomplish these goals, we compared the effect of the presence or absence of prior knowledge of a load on the timing of EMG activity in the postural muscle (biceps femoris [BF]) with that in the focal muscle (anterior deltoid [AD]). Although the sequence of EMG activation was similar under conditions with and without a load, the timing of postural EMG activities (BFi, ipsilateral BF; BFc, contralateral BF) in associated postural adjustments was dependent on the force of arm movement, and the latencies of postural EMG activities (BFi—BFc) were dependent on the speed of arm movement. This indicates that EMG changes in the upper (focal muscle) and lower limbs (postural muscle) were triggered by different motor programs. Moreover, similar EMG activities were observed in postural muscles when the subject had advance knowledge of the presence or the absence of a load. Thus, this suggests that BFi may be centrally preprogrammed (anticipatory regulation) and BFc may be feedback regulated. Furthermore, environmental information may be a critical source of influence on those postural responses.     

Development of temporal and spatial characteristics of anticipatory postural adjustments during gait initiation in children aged 3–10 years

This study aimed to analyze the development of direction specificities of temporal and spatial control and the coordination pattern of anticipatory postural adjustment (APA) along the anteroposterior (AP) and mediolateral (ML) directions during gait initiation (GI) in children aged 3–10 years. This study included 72 healthy children aged 3–10 years and 14 young adults. The child population was divided into four groups by age: 3–4, 5–6, 7–8, and 9–10 years. The GI task included GI using the dominant limb. The peak center of feet pressure (COP) shifts during APAs (APA_peak), initiation time of COP shifts (APA_onset), and the COP vectors in the horizontal plane were calculated to evaluate the direction specificity of spatial, temporal, and coordination control, respectively. A difference in direction specificity development was found for the APA_peak. The APA_peak in the mediolateral axis, but not in the anteroposterior axis, was significantly higher in the 7–8 years age group than in other groups. Although APA_onset was not found for direction specificity, a significant difference between the adult and children groups (5–6 years, 7–8 years, and 9–10 years) was observed in the direction of the COP vector. In conclusion, the developmental process of the spatial, temporal, and coordination control of APAs during GI varied with age. Furthermore, the spatial control and coordination pattern of APAs was found to be direction specific. All components of APAs, namely temporal and spatial control, coordination pattern, and direction specificities, should be analyzed to capture the developmental process of anticipatory postural control.     

Premovement posture and focal movement velocity affects on postural responses accompanying rapid arm movement

Coordination of intentional upper limb movement concurrent with supporting postural activity was investigated in adult males under varying task conditions. Seven subjects performed a 60 deg rapid elbow flexion (focal movement) to a target in movement times of 170, 195, or 220 ms while standing. Measurement of center of pressure via a force platform revealed that subjects adopted individual premovement postural preferences such that locus of center of pressure resided in one predominant quadrant of the foot. Each premovement postural preference was accompanied by one most common postural muscle onset sequence as indicated by bilateral EMG analysis of rectus femoris and biceps femoris. In addition, onset times for postural muscles exhibiting anticipatory postural activity occurred earlier relative to biceps branchii as focal movement velocity increased. The finding that each premovement postural condition was accompanied by one particular postural muscle onset sequence suggested that postural synergies were flexibly organized with respect to onset sequence.     

Older adults exhibit altered motor coordination during an upper limb object transport task requiring a lateral change in support

Investigating an ecologically relevant upper limb task, such as manually transporting an object with a concurrent lateral change in support (sidestepping alongside a kitchen counter), may provide greater insight into potential deficits in postural stability, variability and motor coordination in older adults. Nine healthy young and eleven older, community dwelling adults executed an upper limb object transport task requiring a lateral change in support in two directions at two self-selected speeds, self-paced and fast-paced. Dynamic postural stability and movement variability was quantified via whole-body center of mass motion. The onset of lead lower limb movement in relation to object movement onset was quantified as a measure of motor coordination. Older adults demonstrated similar levels of stability and variability as their younger counterparts, but at slower peak movement velocity and increased task duration. Furthermore, older adults demonstrated asymmetrical motor coordination between left and right task directions, while younger adults remained consistent regardless of task direction. Thus, older adults significantly modulated movement speed and motor coordination to maintain similar levels of stability and variability compared to their younger counterparts.     

Neurobiological degeneracy: Supporting stability,flexibility and pluripotentiality in complex motor skill

This paper investigated neurobiological degeneracy of the motor system that emerged as a function of levels of environmental constraint. Fourteen participants performed a breaststroke-swimming task that required them to develop a specific biomechanically expert pattern and in turn provide the basis for a suitable task vehicle to study the functional role of movement variability. Inter-limb coordination was defined based on the computation of continuous relative phase between elbow and knee oscillators. Unsupervised cluster analysis on arm–leg coordination revealed the existence of different patterns of coordination when participants achieved the same task goal under different levels of environmental constraints (i.e. different amounts of forward resistances). In addition, clusters differed in terms of higher order derivatives (e.g., joint angular velocity, joint amplitude), suggesting an effective role for degeneracy in learning by allowing the exploration of the key relationships between motor organization and interacting constraints. There is evidence to suggest that neurobiological degeneracy supports the potential for motor re-organization to enhance motor learning.     

Time-dependence between upper arm muscles activity during rapid movements: Observation of the proportional effects predicted by the kinematic theory

Rapid human movements can be assimilated to the output of a neuromuscular system with an impulse response modeled by a Delta-Lognormal equation. In such a model, the main assumption concerns the cumulative time delays of the response as it propagates toward the effector following a command. To verify the validity of this assumption, delays between bursts in electromyographic (EMG) signals of agonist and antagonist muscles activated during a rapid hand movement were investigated. Delays were measured between the surface EMG signals of six muscles of the upper limb during single rapid handwriting strokes. From EMG envelopes, regressions were obtained between the timing of the burst of activity produced by each monitored muscle. High correlation coefficients were obtained supporting the proportionality of the cumulative time delays, the basic hypothesis of the Delta-Lognormal model. A paradigm governing the sequence of muscle activities in a rapid movement could, in the long run, be useful for applications dealing with the analysis and synthesis of human movements.     

Age Group Differences in Postural Adjustments Associated With a Stepping Task

In this study, differences among age groups in the postural adjustments associated with a stepping task were identified. Twenty subjects from each of 3 age groups, children (8-12 years), young adults (25-35 years), and older adults (65ndash73 years), performed the task in 2 movement contexts: place and step. In place, the subject simply lifted the foot and placed it on the step. In step, the subject lifted the foot, placed it on the step, and stepped up onto the step. Latencies of postural and focal muscle activation were determined by using surface electromyography and pressure switches. Center of pressure (CP) data were obtained by using a force platform. Subjects in all 3 age groups consistently demonstrated postural adjustments before movement initiation. Children displayed longer postural latencies than young adults as well as disproportionately large values for CP path length. Older adults showed prolonged postural-focal latencies and decreased CP excursions compared with the 2 younger age groups. These results suggest that maturation of coordination between posture and movement may not be fully complete in 8- to l2-year-olds and that increased restraint characterizes the performance of postural adjustments in healthy persons over 65 years of age.     

Attention as a mediating variable in the dynamics of bimanual coordination

The influence of focal attention on the coordination dynamics in a bimanual circle drawing task was investigated. Six right-handed and seven left-handed subjects performed bimanual circling movements, in two modes of coordination, symmetrical or asymmetrical. The frequency of movement was scaled by an auditory metronome from 1.50 Hz to 3.00 Hz in 7 steps. On each trial, subjects were required to attend either to the dominant hand, to a neutral position, or to the nondominant hand.The uniformity of the relative tangential angle was lower in asymmetrical than in symmetrical conditions, but was not influenced by the direction of attention. In the asymmetrical mode, shifts in RTA relations, suggestive of loss of stability, were evident as the movement frequency was increased. Typically, these shifts were mediated by distortions of the trajectory of the nondominant limb. When the nondominant hand was the focus of attention, movements of this hand were more circular, and temporal variability was reduced, at the cost of a greater deviation from the target frequency. Movements of the dominant hand were not affected by the direction of attention. The findings show that although directed attention acts to modify the coordination dynamics, it does so primarily at the level of the individual hands, rather then in terms of the relation between them.     

视觉预期和注意指向对姿势和动作肌肉预期和补偿姿势调节的影响

采用经典落球试验研究范式,同步观察视觉预期和注意指向对腰部姿势肌肉和上肢运动肌肉预期和补偿姿势调节的影响,探索视觉预期和注意指向影响姿势控制的早期心理生理机制。24名青年志愿者(10名男性,14名女性)参与完成本实验,分别在有、无视觉预期以及注意指向"托盘稳定"或者"重心稳定"的实验条件下观察外部姿势干扰对腰部姿势肌肉(L5~S1腰部多裂肌)和上肢动作肌肉(肱二头肌)预期姿势调节(anticipatory postural adjustments,APAs)和补偿姿势调节(compensatory postural adjustments,CPAs)相关时间和强度参数的影响。APAs和CPAs的时间和强度参数通过获取被检肌肉s EMG信号并参照相关检测规范进行。结果显示:(1)视觉预期对多裂肌的APAs启动时间,对肱二头肌的APAs启动时间、APAs强度和CPAs强度有显著影响;(2)注意指向对多裂肌的CPAs启动时间和肱二头肌APAs启动时间有显著影响;(3)视觉预期和注意指向对肱二头肌的APAs启动时间和APAs强度有交互作用。研究认为,突发外部姿势干扰条件下姿势肌肉和动作肌肉的姿势调节策略具有一定的差异,视觉预期和注意指向仅对姿势肌肉的时间参数有影响,对动作肌肉APAs和CPAs时间和强度参数都产生调节作用,表明在中枢神经系统的姿势控制中,人体姿势策略的调节是通过对姿势肌肉和动作肌肉的双重控制来完成的,视觉预期效应和心理指向效应反映在对不同功能肌肉前馈控制和反馈控制相应参数的调节。     

Cancelling discrete and stopping ongoing rhythmic movements: Do they involve the same process of motor inhibition?

Motor inhibition is considered to be an important process of executive control and to be implicated in numerous activities in order to cancel prepared actions and, supposedly, to suppress ongoing ones. Usually, it is evaluated using a “stop-signal task” in which participants have to inhibit prepared discrete movements. However, it is unknown whether other movement types involve the same inhibition process. We therefore investigated whether the inhibition process for discrete movements is involved in stopping ongoing rhythmic movements as well.Twenty healthy adults performed two counterbalanced tasks. The first task was used to estimate the stop-signal reaction time (SSRTd) needed to inhibit prepared discrete key-pressing movements. In the second task, participants drew graphic patterns on a tablet and had to stop the movement when a stop-signal occurred. We calculated the rhythmic stop signal-reaction time as the time needed to initiate stopping such ongoing rhythmic movement (SSRTr) and the same latency relative to the period of the rhythmic movement (relSSRTr). We measured these delays under different movement frequencies and motor coordination conditions and further investigated whether they varied as a function of several parameters of the rhythmic movements (speed, mean and variance of the relative phase, and movement phase at several time events).We found no correlation between inhibition measures in the two tasks. In contrast, generalized linear models showed a moderate yet significant influence of the motion parameters on the inhibition of ongoing rhythmic movements. We therefore conclude that the motor inhibition processes involved in cancelling prepared discrete movements and stopping ongoing rhythmic movements are dissimilar.     

Effects of anticipation certainty on preparatory brain activity and anticipatory postural adjustments associated with voluntary unilateral arm movement while standing

We examined the effects of anticipation certainty concerning which voluntary movement is required in response to a stimulus while standing on preparatory brain activity and anticipatory postural adjustments (APAs). Ten right-handed adults abducted their left or right arm rapidly in response to a visual imperative stimulus, based on the type of stimulus. A warning cue, which did or did not contain information about the side of arm abduction, was presented 2000ms before the imperative stimulus. Preparatory brain activity before arm abduction was quantified by the mean amplitude of the contingent negative variation 100ms before the imperative stimulus (late CNV amplitude). Compared with the low anticipation condition, in the high anticipation condition the following results were obtained only in the case of right arm abduction: (1) larger late CNV amplitude, (2) earlier postural muscle activities with respect to the focal muscle of arm abduction, and (3) smaller peak displacement of center of pressure during the abduction. These findings suggest that high anticipation of voluntary movement of dominant arm to a stimulus while standing influences preparatory brain activity before the movement, resulting in earlier APAs and thus smaller disturbance of postural equilibrium during the movement.     

Reorganised anticipatory postural adjustments due to experimental lower extremity muscle pain

Automated movements adjusting postural control may be hampered during musculoskeletal pain leaving a risk of incomplete control of balance. This study investigated the effect of experimental muscle pain on anticipatory postural adjustments by reaction task movements. While standing, nine healthy males performed two reaction time tasks (shoulder flexion of dominant side and bilateral heel lift) before, during and after experimental muscle pain. On two different days experimental pain was induced in the m. vastus medialis (VM) or the m. tibialis anterior (TA) of the dominant side by injections of hypertonic saline (1 ml, 5.8%). Isotonic saline (1 ml, 0.9%) was used as control injection. Electromyography (EMG) was recorded from 13 muscles. EMG onset, EMG amplitude, and kinematic parameters (shoulder and ankle joint) were extracted. During shoulder flexion and VM pain the onset of the ipsilateral biceps femoris was significantly faster than baseline and post injection sessions. During heels lift in the VM and TA pain conditions the onset of the contralateral TA was significantly faster than baseline and post injection sessions in bilateral side. VM pain significantly reduced m. quadriceps femoris activity and TA pain significantly reduced ipsilateral VM activity and TA activity during bilateral heel lift. The EMG reaction time was delayed in bilateral soleus muscles during heels lift with VM and TA pain. The faster onset of postural muscle activity during anticipatory postural adjustments may suggest a compensatory function to maintain postural control whereas the reduced postural muscle activity during APAs may indicate a pain adaptation strategy to avoid secondary damage.     

Effects of vision and cognitive load on anticipatory and compensatory postural control

This study assessed the effects of vision and cognitive load on anticipatory postural adjustments (APAs) and compensatory postural adjustments (CPAs) in response to an externally triggered postural perturbation. A ball-hitting test was repeated under different visual conditions (eyes open, EO; eyes closed, EC) and cognitive loads (no load, 3-subtraction task, time-limited 3-subtraction task). Data were collected separately for I) surface electromyography from the right side of the biceps brachii (BIC) and erector spinae (ES) to detect the latency and response intensity (RI); and II) displacement of the centre of pressure (ΔCOP) to detect the standard deviation (ΔCOP_SD) and maximum value (ΔCOP_max) in the anterior-posterior direction. Compared with the results under the EC condition, the ES latency was shorter and the RI of the BIC was lower under the EO condition. Accordingly, the ΔCOP_SD and ΔCOP_max were increased in the APAs phase and decreased in the CPAs phase. Cognitive load had no effect on APAs and CPAs or on ΔCOP in the APAs phase. However, ΔCOP_max was decreased in the CPAs phase during the EC condition. In conclusion, vision played an important role in APAs and CPAs for muscle activation and ΔCOP. Cognitive load had no effect on neuromuscular APAs or CPAs except when the postural perturbation occurred when visually unexpected.