Pilot study of light therapy and neurocognitive performance of attention and memory in healthy subjects

The aim of this pilot study was to investigate whether light therapy improves healthy subjects' neurocognitive performance of attention, memory, and language. Ten subjects were treated with white bright light for 5 days and a control group of 10 with no treatment were assessed with a battery of neurocognitive tests which included the Stroop Colour Word Interference Test, the Verbal Fluency Test, the Story Recall Test, and the Word Pairs Recall Test. Analysis showed improvements in cognitive scores in both groups, although on all the cognitive tests the mean difference scores between baseline and endpoint were significantly larger in the light-treated group. These preliminary results suggest that short-term bright light may exert beneficial effects on cognitive functions.     

Verbal and visuo-spatial memory Two clinical tests administered to a group of normal subjects

Abstract.— A group of 165 normal subjects were examined on two memory tests in clinical use, the Word Pairs Test and the Visual Gestalts Test. The purpose of the study was to establish norms with the variables of age, sex, and length of schooling being taken into consideration. During the learning phase a complex interaction between all three factors was found for the Word Pairs, whereas in the Visual Gestalts scores were only affected by age. In the delayed memory task used in both tests, age was again found to be the only significant factor. Using quartile scores, it was found that females performed better than males on the verbal test and vice versa on the visuo-spatial test. Normative data are presented for three age groups. A significant decline in performance appeared in the age group 40–49 years. The data became more heterogenous with an increase in the age of the subjects.     

Reading times and adaptive styles among patients diagnosed with psychosis as assessed by the Serial Color-Word Test

The present study focuses on how patients diagnosed with psychosis deal with a conflicting situation. In the study, two groups of patients were assessed. One group consisted of patients diagnosed with psychosis (n = 41), while the comparison group (n = 135) consisted of inpatients diagnosed either with anorexia nervosa or with bulimia nervosa. The groups were assessed using the Serial Color Word Test (S-CWT), designed for studying an individual's successive adaptation over time to a conflicting situation. The S-CWT differentiated the two groups regarding both reading time and adaptive styles. Patients diagnosed with psychosis had longer reading times and an adaptive style that was deviant throughout the test, indicating poorer cognitive functioning and more serious psychopathology. These problems may in turn influence functioning in work or study and daily living, all of which are important in treatment planning.     

Relations between self-serving cognitive distortions,psychopathic traits,and antisocial behavior in a non-clinical sample of adolescents

The aim of the present study was to assess the relative contributions self-serving cognitive distortions and psychopathic traits to adolescent antisocial behavior. Participants were 972 high-school students who completed self-report questionnaires. Hierarchical multiple regression analyses showed that self-serving cognitive distortions, psychopathic traits, as well as their interaction term were significant predictors of antisocial behavior in both genders after adjustment for the main other cognitive, psychopathological and sociofamilial variables. High levels of self-serving cognitive distortions were associated with more extensive antisocial behavior among participants with higher scores on psychopathic traits. This result may have implications for prevention and treatment.     

Relations between self-serving cognitive distortions, psychopathic traits, and antisocial behavior in a non-clinical sample of adolescents

The aim of the present study was to assess the relative contributions self-serving cognitive distortions and psychopathic traits to adolescent antisocial behavior. Participants were 972 high-school students who completed self-report questionnaires. Hierarchical multiple regression analyses showed that self-serving cognitive distortions, psychopathic traits, as well as their interaction term were significant predictors of antisocial behavior in both genders after adjustment for the main other cognitive, psychopathological and sociofamilial variables. High levels of self-serving cognitive distortions were associated with more extensive antisocial behavior among participants with higher scores on psychopathic traits. This result may have implications for prevention and treatment.     

RATINGS OF ANXIETY-PRONENESS AND RESPONSES TO ELECTRICAL PAIN STIMULATION: Preliminary experiments in a group of young delinquents

A group of young delinquents clinically rated as manifesting a tendency to react with anxiety and tension was compared with a group from the same prison with predominantly 'psychopathic' traits according to clinical ratings. The delinquents were subjected to electrical pain stimulation and tested with a battery of tests and personality inventories. In line with the hypotheses, the more anxiety-prone delinquents showed greater sensitivity to pain, had lower scores in the Leg Persistence Test, shorter reaction times and more errors in an auditive choice reaction test. There were no significant differences with regard to the inventory variables.     

A preliminary study of Hare's “Research Scale for the Assessment of Psychopathy” in mentally-abnormal offenders

The abbreviated (15-item) version of Hare's Research Scale for the Assessment of Psychopathy (RSAP) was investigated in a sample of male admissions to Broadmoor Special Hospital (N = 50), along with five MMPI measures relevant to psychopathy (Impulsivity, Sociability, Psychopathic Deviate, Anxiety and Sociopathy). Patients were assigned to one of four clinical diagnostic groups: Personality Disorder, Mixed (personality disorder with schizophrenia), Schizophrenia and Affective Disorder. Results indicated that while both psychopathic groups (Mixed and Personality Disorder) showed high scores on almost all RSAP items, the Affective Disorder group showed low scores on almost all items. Results of a discriminant function analysis indicated that Hare's RSAP was superior to the MMPI measures at discriminating between psychopaths and non-psychopaths. Use of the discriminant function to re-allocate patients to criterion groups showed a high hit rate (94%) for psychopathic patients but a hit rate of only 61% for non-psychopathic patients. Half of the schizophrenic patients were mis-allocated to the psychopathic group. The results support the idea of an affective deficit common to psychopaths and schizophrenics, but suggest that psychopaths additionally show a deficit which may be characterized by a lack of goal-directed behaviour.     

Impact of simulated visual impairment on the cognitive test performance of young adults

Aims. This study investigated the effect of simulated visual impairment on the speed and accuracy of performance on a series of commonly used cognitive tests. Methods. Cognitive performance was assessed for 30 young, visually normal subjects (M=22.0±3.1 years) using the Digit Symbol Substitution Test (DSST), Trail Making Test (TMT) A and B and the Stroop Colour Word Test under three visual conditions: normal vision and two levels of visually degrading filters (Vistech^TM) administered in a random order. Distance visual acuity and contrast sensitivity were also assessed for each filter condition. Results. The visual filters, which degraded contrast sensitivity to a greater extent than visual acuity, significantly increased the time to complete (p<.05), but not the number of errors made, on the DSST and the TMT A and B and affected only some components of the Stroop test. Conclusions. Reduced contrast sensitivity had a marked effect on the speed but not the accuracy of performance on commonly used cognitive tests, even in young individuals; the implications of these findings are discussed.     

Relationships between cognitive and behavioral measures of executive function in children with brain disease.

This study addressed the clinical and construct validity of the Behavior Rating Inventory of Executive Function. (BRIEF: Gioia, Isquith, Guy, & Kenworthy, 2000), a questionnaire designed to tap behavioral aspects of executive functions in children. BRIEF profiles in early treated phenylketonuria (PKU; n=44), early treated hydrocephalus (n=45), frontal focal lesions (n=20) and controls (n=80) were examined. Clinical validity was supported through significant between-group comparisons, especially between the frontal focal lesion group and other groups. To examine construct validity, raw scores on cognitive executive function measures including the Contingency Naming Test (CNT), Rey Complex Figure (RCF), Tower of London (TOL), and Controlled Oral Word Association Test (COWAT), were correlated with BRIEF scale scores. Few significant correlations were found, indicating cognitive and behavioral measures appear to tap different constructs within the executive function domain. A dissociation was found between behavioral and cognitive impairments in the frontal as opposed to PKU and hydrocephalus groups. This is discussed in relation to underlying pathology, the cognitive measures used, and possible limitations in the BRIEF's usefulness for measuring behavioral executive dysfunction in groups only mildly affected by neurological compromise.     

Relationships Between Cognitive and Behavioral Measures of Executive Function in Children With Brain Disease

This study addressed the clinical and construct validity of the Behavior Rating Inventory of Executive Function. (BRIEF: Gioia, Isquith, Guy, & Kenworthy, 2000), a questionnaire designed to tap behavioral aspects of executive functions in children. BRIEF profiles in early treated phenylketonuria (PKU; n = 44), early treated hydrocephalus (n = 45), frontal focal lesions (n = 20) and controls (n = 80) were examined. Clinical validity was supported through significant between-group comparisons, especially between the frontal focal lesion group and other groups. To examine construct validity, raw scores on cognitive executive function measures including the Contingency Naming Test (CNT), Rey Complex Figure (RCF), Tower of London (TOL), and Controlled Oral Word Association Test (COWAT), were correlated with BRIEF scale scores. Few significant correlations were found, indicating cognitive and behavioral measures appear to tap different constructs within the executive function domain. A dissociation was found between behavioral and cognitive impairments in the frontal as opposed to PKU and hydrocephalus groups. This is discussed in relation to underlying pathology, the cognitive measures used, and possible limitations in the BRIEF's usefulness for measuring behavioral executive dysfunction in groups only mildly affected by neurological compromise.     

Attention Network Performance and Psychopathic Symptoms in Early Adolescence: An ERP Study

Reaction time (RT) and event-related potential (ERP) measures were used to examine the relationships between psychopathic symptoms and three major attention networks (alerting, orienting, and executive attention) among a community sample of youth. Antisocial Process Screening Device (APSD; Frick and Hare 2001) total and subscale scores were negatively correlated with ERP measures of attentional alerting, indicating that youth with psychopathic symptoms had difficulty using warning cues to prepare for upcoming targets. APSD total scores were not related to performance on measures of orienting or executive attention, although weaker executive attention was found among youth with higher scores on the Impulsivity subscale. These findings support attention-based models of psychopathy and provide evidence of specific deficits in attentional alerting among youth with psychopathic traits. Deficiencies in attentional alerting may be related to noradrenergic functioning and may have cascading effects on higher order cognitive and affective processing.     

A Rorschach Investigation of Narcissism and Hysteria in Antisocial Personality

We investigated Rorschach responses associated with narcissism and hysteria in a group of antisocial personality disordered offenders. The Rorschach protocols of 42 subjects who met the criteria from the Diagnostic and Statistical Manual of Mental Disorders (3rd ed., rev. [DSM-III-R]; American Psychiatric Association, 1987) for antisocial personality disorder were analyzed using Exner's (1986) criteria for pairs, reflections, and personal responses, and Gacono's (1988) criteria for the impressionistic response. Severe, or primary psychopaths (n = 21), scoring ≥30 on the Hare (1980) Psychopathy Checklist (PCL), were compared to moderate, or secondary pscyhopaths (n = 21), scoring <30 on the PCL. The mean number of pair and impressionistic responses did not significantly differ for the two antisocial groups. The highly psychopathic group, however, did exhibit a significantly greater mean number of reflection and personal responses. We discuss pair and reflection responses and their relationship to narcissism in psychopathic disturbance. We recommend interpreting the personal response within the context of the psychopathic character and view personal responses as expressions of narcissism and omnipotence in highly psychopathic subjects. We also hypothesize that the impressionistic responses are indicative of primitive dissociative processes and hysteria in psychopathic subjects, and that their presence provides construct validity for the work of Guze (1976) and others who suggested an underlying histrionic dimension to psychopathy.     

Performance of chronotypes on memory tests during the morning and the evening shifts

Memory consists of several phases or processes that can be influenced by many factors, including the individual's circadian rhythm and the time of day at which tests are performed. The present objective was to evaluate the performance on memory tests of different chronotypes during the morning and the evening shifts. Subjects (21 men and 26 women, between the ages of 20 and 35 yr.) were evaluated for memory and metamemory differences in the morning and in the afternoon, using a battery of neuropsychological tests composed of the Word List with Emotional Content, Visual Memory, Scale-Semantic Memory, Digit Span, Word-Pairs Associated, Verbal Fluency Test, and Metamemory questionnaire. In the evening shift, there was a statistical difference among chronotypes on the Word List with Neutral Content and on the Verbal Fluency Test. In the morning, there were no statistically significant differences; however, the morning-type subjects had higher scores on the metamemory tests (p<.01), while the evening-type subjects had higher scores in the afternoon (p<.01). In spite of their perception, on Word-Pairs Associated and Word List with Emotional Content, the subjects, independently of their chronotype, showed better performance by the evening than by the morning shift. These results highlight the importance of controlling the shift of day and chronotype in studies with the objective of exploration of human performance.     

Adaptive regression and types of cognitive flexibility

The relationship between adaptive regression and cognitive flexibility was explored in a group of 42 college students. Adaptive regression was measured with the Holt scoring system for the Rorschach. One type of cognitive flexibility was measured by Guilford's tests of divergent production (Word Fluency, Associational Fluency, and Alternate Uses) and a second type by Mednick's Remote Associates Test. Adaptive regression was found to be significantly positively related to the Remote Associates Test in males but not in females. Adaptive regression was found to be unrelated to divergent production tests. These relationships were not found to be mediated by Rorschach productivity or verbal intelligence. A two-stage process was proposed to account for the cognitive operations underlying adaptive regression and the Remote Associates Test. The first stage is seen as a generative (primary process) stage, while the second stage is seen as an evaluative (secondary process) stage. Possible reasons for sex differences were also discussed.     

A Rorschach investigation of narcissism and hysteria in antisocial personality

We investigated Rorschach responses associated with narcissism and hysteria in a group of antisocial personality disordered offenders. The Rorschach protocols of 42 subjects who met the criteria from the Diagnostic and Statistical Manual of Mental Disorders (3rd ed., rev. [DSM-III-R]; American Psychiatric Association, 1987) for antisocial personality disorder were analyzed using Exner's (1986) criteria for pairs, reflections, and personal responses, and Gacono's (1988) criteria for the impressionistic response. Severe, or primary psychopaths (n = 21), scoring greater than or equal to 30 on the Hare (1980) Psychopathy Checklist (PCL), were compared to moderate, or secondary pscyhopaths (n = 21), scoring less than 30 on the PCL. The mean number of pair and impressionistic responses did not significantly differ for the two antisocial groups. The highly psychopathic group, however, did exhibit a significantly greater mean number of reflection and personal responses. We discuss pair and reflection responses and their relationship to narcissism in psychopathic disturbance. We recommend interpreting the personal response within the context of the psychopathic character and view personal responses as expressions of narcissism and omnipotence in highly psychopathic subjects. We also hypothesize that the impressionistic responses are indicative of primitive dissociative processes and hysteria in psychopathic subjects, and that their presence provides construct validity for the work of Guze (1976) and others who suggested an underlying histrionic dimension to psychopathy.     

Stability and predictors of psychopathic traits from mid‐adolescence through early adulthood

High levels of psychopathic traits in youth are associated with multiple negative outcomes including substance misuse, aggressive behavior, and criminality. Evidence regarding stability of psychopathic traits is contradictory. No previous study has examined long‐term stability of psychopathic traits assessed with validated clinical measures. The present study examined the stability of psychopathic traits from mid‐adolescence to early adulthood and explored adolescent factors that predicted psychopathic traits five years later. The sample included 99 women and 81 men who had consulted a clinic for substance misuse in adolescence. At an average age of 16.8 years, the adolescents were assessed using the Psychopathy Checklist: Youth Version (PCL: YV) and five years later using the PCL‐Revised (PCL‐R). Additionally, extensive clinical assessments of the adolescents and their parents were completed in mid‐adolescence. Among both females and males, moderate to high rank‐order stability was observed for total PCL and facet scores. Among both females and males, there was a decrease in the mean total PCL score, interpersonal facet score, affective facet score, and lifestyle facet score. However, the great majority of females and males showed no change in psychopathy scores over the five‐year period as indicated by the Reliable Change Index. Despite the measures of multiple family and individual factors in adolescence, only aggressive behavior and male sex predicted PCL‐R total scores in early adulthood after taking account of PCL:YV scores. Taken together, these results from a sample who engaged in antisocial behavior in adolescence suggest that factors promoting high psychopathy scores act early in life.     

Enduring cognitive dysfunction in unipolar major depression: A test–retest study using the Stroop paradigm

Hammar, Å., Sørensen, L., Årdal, G., Oedegaard, K.J., Kroken, R., Roness, A. & Lund, A. (2009). Enduring cognitive dysfunction in unipolar major depression: A test–retest study using the Stroop‐paradigm. Scandinavian Journal of Psychology. The aim of the study was to investigate automatic and effortful information processing with the Stroop paradigm in a long term perspective in patients with major depressive disorder (MDD). Patients were tested at two test occasions: at inclusion with a Hamilton Depression Rating Scale (HDRS) score >18, and after 6 months, when most patients had experienced symptom reduction. The Stroop paradigm is considered to measure aspects of attention and executive functioning and consists of three conditions/cards: naming the color of the patches (Color), reading of the color‐words (Word) and naming the ink color of color‐words (Color‐Word). The Color‐Word condition is proved to be the most cognitive demanding task and requires the proband to actively suppress interference and is therefore considered to require more effortful information processing, whereas naming the color of the patches and reading the color‐words are expected to be more automatic and less cognitive demanding. A homogenous group of 19 patients with unipolar recurrent MDD according to DSM‐IV and a HDRS score of >18 were included in the study. A control group was individually matched for age, gender and level of education. Depressed patients performed equal to the control group on the Color and Word cards at both test occasions. However, the patients were impaired compared with the control group on the Color‐Word card task at both test occasions. Thus, the depressed patients showed no improvement of effortful attention/executive performance as a function of symptom reduction. The results indicate that the depressed patients showed impaired cognitive performance on cognitive demanding tasks when symptomatic and that this impairment prevailed after 6 months, despite significant improvement in their depressive symptoms.     

The relationship between psychopathic traits and attachment behavior in a non-clinical population

Attachment processes have been proposed to play a key role in the development of the core features of psychopathy (Fowles & Dindo, 2006). The findings reported in the literature regarding the associations between attachment and psychopathic traits are far from conclusive, especially in non-clinical populations. The present study investigated the relationship between self-reported attachment behavior and psychopathic traits in a college sample. Two-hundred nine participants completed the Experiences in Close Relationships-Revised scale and the Levenson Self-Report Psychopathy scale. Controlling for gender and race, hierarchical multiple regression analyses indicated that individuals high in both attachment avoidance and attachment anxiety had higher primary psychopathy scores. Both individuals high in attachment avoidance and individuals high in attachment anxiety had higher secondary psychopathy scores. Implications of these findings for future research and clinical practice are discussed.     

Development of Prospective Memory: Tasks Based on the Prefrontal-Lobe Model

This study investigated the development of prospective memory using tasks based on the prefrontal-lobe model. Three groups each of 30 children, adolescents, and young adults were compared on prospective-memory performance using ongoing tasks with two levels of cognitive demand (low and high), and two levels of importance (unstressed and stressed) of remembering prospective cues. The Self-Ordered Pointing Task (SOPT), Stroop Color Word Interference Test, and Tower of London were also used to assess relationships between prospective memory and prefrontal-lobe functions. The children remembered fewer prospective cues than either the adolescents or adults, but the adolescents and adults remembered equally well. This trend increased significantly as the cognitive demand of the ongoing tasks increased. However, stressing or not stressing the importance of remembering made no difference to prospective-memory performance. Performance on the SOPT and Stroop Colour Word Interference predicted performance on the high- but not on the low-demand condition. These findings implicate the maturation of the brain's prefrontal region in the development of prospective memory.     

Neuropsychological correlates of psychopathic traits in a non-incarcerated sample

The present study examined the association between neuropsychological behavioral performance and psychopathic personality traits, measured via the Psychopathic Personality Inventory (PPI), in a non-incarcerated sample. Specifically, performance involving general executive cognitive functioning (ECF) and response inhibition was investigated in regards to the two main psychopathy factors (affective-interpersonal and social deviance) of the PPI. A group of 95 student volunteers were administered the PPI and a variety of neuropsychological measures. Analyses revealed that total PPI scores were related to deficits in response inhibition but not general ECF. However, this relationship was qualified by the differential associations observed for the two PPI factors. The social deviance factor was associated with deficits in general ECF and response inhibition, whereas the affective-interpersonal facet was associated with enhanced general ECF performance but not response inhibition. The results suggest that cognitive functioning shows predicted associations with a self-report measure of psychopathy among non-incarcerated young adults, providing further evidence for psychopathy conceptualizations from a normal-range personality perspective.