BIOLOGICAL SIGNIFICANCE AS A DETERMINANT OF CUE COMPETITION

Abstract— Many researchers have noted the similarities between causal judgment in humans and Pavlovian conditioning in animals. One recently noted discrepancy between these two forms of learning is the absence of backward blocking in animals, in contrast with its occurrence in human causality judgment. Here we report two experiments that investigated the role of biological significance in backward blocking as a potential explanation of this discrepancy. With rats as subjects, we used sensory preconditioning and second-order conditioning procedures, which allowed the to-be-blocked cue to retain low biological significance during training for some animals, but not for others. Backward blocking was observed only when the target cue was of low biological significance during training. These results suggest that the apparent discrepancy between human causal judgment and animal Pavlovian conditioning arises not because of a species difference, but because human causality studies ordinarily use stimuli of low biological significance, whereas animal Pavlovian studies ordinarily use stimuli of high biological significance, which are apparently protected against cue competition.     

When All Is Still Concealed: Are We Closer to Understanding the Mechanisms Underlying Evaluative Conditioning?

Fulcher and Hammerl's (2001) important exploration of the role of contingency awareness in evaluative conditioning (EC) raises a lot of issues for discussion: (1) what boundaries, if any, exist between EC and affective learning paradigms?; (2) if EC does occur without awareness does this mean it is nonpropositional learning?; (3) is EC driven by stimulus-response (S-R), rather than stimulus-stimulus (S-S), associations and if so should it then surprise us that contingency awareness is not important?; and (4) if S-R associations are at the heart of EC, should we automatically assume EC is part of a different learning mechanism to autonomic Pavlovian conditioning (Field, 2000a, 2000b)? This article, after a critical review of Fulcher and Hammerl's work, discusses these issues with reference to what can be realistically inferred about the mechanisms underlying EC.     

Metacognitive errors in change detection: missing the gap between lab and life

Studies of change detection suggest that people tend to overestimate their ability to detect visual changes. In a recent laboratory study of change detection and human intention, Beck et al., found that individuals have an inadequate understanding that intention can improve change detection performance and that its importance increases with scene complexity. We note that these findings may be specific to unfamiliar situations such as those generated routinely in studies of change detection. In two questionnaire studies, we demonstrate that when participants consider real world scenarios such as driving, people are well aware that the intention to detect changes improves detection performance, especially in complex scenes. We suggest several reasons why change detection findings like Beck et al.'s do not generalize to real world situations. More broadly, we suggest a possible way to bridge the gap between lab and life.     

Some recalcitrant views on the role of noncognitive S-R factors in human pavlovian autonomic conditioning

Either implicitly or explicitly, most workers in the last two decades have adopted the (imperialistic) view that conditioning is simply the learning of (cognitive) S-S relationships, and that (noncognitive) S-R factors are irrelevant. I shall remind us of some contrary evidence from human Pavlovian autonomic conditioning (HPAC), consideration of which may spoil our neat cognitive picture (representation?) of the world, but may also lead both to a better understanding of the conditioning phenomenon and to more genuinely useful applications of conditioning principles to behavioral (including psychophysiological) problems.     

Some recalcitrant views on the role of noncognitive S-R factors in human Pavlovian autonomic conditioning. Some facts still haunt us

Either implicitly or explicity, most workers in the last two decades have adopted the (imperialistic) view that conditioning is simply the learning of (cognitive) S-S relationships, and that (noncognitive) S-R factors are irrelevant. I shall remind us of some contrary evidence from human Pavlovian autonomic conditioning (HPAC), consideration of which may spoil our neat cognitive picture (representation?) of the world, but may also lead both to a better understanding of the conditioning phenomenon and to more genuinely useful applications of conditioning principles to behavioral (including psychophysiological) problems.     

Pavlovian eyeblink conditioning in combat veterans with and without post-traumatic stress disorder

Several recent studies have investigated relationships between post-traumatic stress disorder (PTSD) and learning and memory problems. These reports have found in general that not only does PTSD affect trauma-related memories, but when patients with PTSD are compared with similar trauma patients without PTSD, general memory impairments have been found. The present paper reports a study in which associative learning, using Pavlovian eyeblink conditioning, was investigated in combat veterans with and without chronic PTSD, using interstimulus intervals of 500 and 1000 msec in two separate experiments. Although several recent reports suggest that larger-magnitude autonomic conditioned responses occur in patients with PTSD during Pavlovian conditoning, the present study found evidence of impaired Pavlovian eyeblink conditioning in combat veterans with and without PTSD, compared to non-combat veterans. Although these data suggest that combat leads to an impaired associative learning process regardless of whether PTSD is apparent, a group of community-dwelling combat veterans not under medical treatment showed normal conditioning, suggesting that variables other than prior combat must also be involved.     

Pavlovian Eyeblink Conditioning in Combat Veterans With and Without Post-Traumatic Stress Disorder

Several recent studies have investigated relationships between post-traumatic stress disorder (PTSD) and learning and memory problems. These reports have found in general that not only does PTSD affect trauma-related memories, but when patients with PTSD are compared with similar trauma patients without PTSD, general memory impairments have been found. The present paper reports a study in which associative learning, using Pavlovian eyeblink conditioning, was investigated in combat veterans with and without chronic PTSD, using interstimulus intervals of 500 and 1000 msec in two separate experiments. Although several recent reports suggest that larger-magnitude autonomic conditioned responses occur in patients with PTSD during Pavlovian conditioning, the present study found evidence of impaired Pavlovian eyeblink conditioning in combat veterans with and without PTSD, compared to non-combat veterans. Although these data suggest that combat leads to an impaired associative learning process regardless of whether PTSD is apparent, a group of community-dwelling combat veterans not under medical treatment showed normal conditioning, suggesting that variables other than prior combat must also be involved.     

Pavlovian conditioning of sexual arousal: parametric and background manipulations

Recent studies have shown that a Pavlovian conditioned stimulus (CS) for unconsummated sexual arousal can increase the rate of copulation in the rat. This report includes five experiments examining the effects of parametric manipulations on the conditioned arousal response. Results show that between six and nine trials are necessary for reliable conditioning, but extinction is somewhat slower than acquisition. The function for the CS-US (unconditioned stimulus) interval is quadratic, with a minimum of several minutes required for effective conditioning. In the first three experiments, it appeared that background cues were conditioned as well as the designated CSs, and this was tested explicitly in the last two studies. In one, the effect of background cues was shown by training and testing in different situations; in the second, background cues were shown to be subject to latent inhibition. These results demonstrate the influence of Pavlovian learning in sexual behavior and help to provide the basis for an animal model of the acquisition of deviant sexual arousal in humans.     

Pavlovian feed-forward mechanisms in the control of social behavior

The conceptual and investigative tools for the analysis of social behavior can be expanded by integrating biological theory, control systems theory, and Pavlovian conditioning. Biological theory has focused on the costs and benefits of social behavior from ecological and evolutionary perspectives. In contrast, control systems theory is concerned with how machines achieve a particular goal or purpose. The accurate operation of a system often requires feed-forward mechanisms that adjust system performance in anticipation of future inputs. Pavlovian conditioning is ideally suited to subserve this function in behavioral systems. Pavlovian mechanisms have been demonstrated in various aspects of sexual behavior, maternal lactation, and infant suckling. Pavlovian conditioning of agonistic behavior has been also reported, and Pavlovian processes may likewise be involved in social play and social grooming. Several further lines of evidence indicate that Pavlovian conditioning can increase the efficiency and effectiveness of social interactions, thereby improving their cost/benefit ratio. We extend Pavlovian concepts beyond the traditional domain of discrete secretory and other physiological reflexes to complex real-world behavioral interactions and apply abstract laboratory analyses of the mechanisms of associative learning to the daily challenges animals face as they interact with one another in their natural environments.     

Pavlovian conditioning in human skilled motor behavior

The role of Pavlovian contingencies in human skilled motor behavior was investigated in three experiments by means of a new conditioning preparation. In Experiment 1 the present method was shown to be appropriate for the study of associative learning. Subjects who experienced a standard delay configuration performed significantly more conditioned responses than subjects who received either backward conditioning or random pairings. Stimulus generalization was shown to be slight in two additional groups. Subsequent experiments examined conditioning with multiple conditioned stimuli (CSs). In particular, in Experiment 2 some reciprocal overshadowing was demonstrated when two conditional stimuli (tone and vibration) were compounded. Experiment 3 investigated blocking. Blocking was less than expected, however. Subjects’ perceptions of the stimuli and reaction time data suggest that a certain proportion had shifted their attention to the added element of the CS compound. Results are discussed in relation to other studies on Pavlovian learning in humans and animals, which are concerned with “stimulus selection.”     

The effect of comparative context on evaluative conditioning

Evaluative conditioning (EC) is a change in the evaluation of a stimulus after the stimulus co-occurred with affective stimuli. The present research examined whether EC of one stimulus depends also on the co-occurrence of another stimulus with positive or negative stimuli. We paired two target people with affective stimuli. We found that a person who appeared eight times with positive stimuli and eight times with negative stimuli was liked more when the other person appeared always (16 times) with negative stimuli than when the other person appeared always with positive stimuli. The manipulation did not change the US evaluation or the general standard on the value dimension of what a positive or negative stimulus is. We suggest that like other evaluative traits (e.g., evil, pretty) co-occurrence with affective stimuli is sensitive to temporary standards. The manipulation changed the standard of what co-occurrence with affective stimuli is considered positive versus negative.     

I like it, but I'm not sure why: can evaluative conditioning occur without conscious awareness?

There is good evidence that, in general, autonomic conditioning in humans occurs only when subjects can verbalize the contingencies of conditioning. However, one form of conditioning, evaluative conditioning (EC), seems exceptional in that a growing body of evidence suggests that it can occur without conscious contingency awareness. As such, EC offers a unique insight into what role contingency awareness might play in associative learning. Despite this evidence, there are reasons to doubt that evaluative conditioning can occur without conscious awareness. This paper aims to critically review the EC literature and to draw some parallels to what is known about autonomic conditioning. In doing so, some important general issues about measuring contingency awareness are raised. These issues are illustrated with a brief report of an experiment in which a sensitive measure of contingency awareness is compared against a commonly used measure.     

Both trace and delay conditioning of evaluative responses depend on contingency awareness

Whereas previous evaluative conditioning (EC) studies produced inconsistent results concerning the role of contingency knowledge, there are classical eye-blink conditioning studies suggesting that declarative processes are involved in trace conditioning but not in delay conditioning. In two EC experiments pairing neutral sounds (conditioned stimuli; CSs) with affective pictures (unconditioned stimuli; USs), we tested whether the type of conditioning procedure affects the relationship between awareness and EC. Auditory CSs and visual USs were either overlapping and co-terminating (Delay Conditioning Group), or they were separated by a short temporal gap (Trace Conditioning Group). In both groups, contingency awareness was manipulated by varying the duration at which the US was presented during conditioning. Furthermore, in addition to a post-conditioning measure of awareness, US detectability was measured concurrently during the learning phase in Experiment 2. US exposure duration affected both measures of awareness. The data of both experiments demonstrate that EC does not occur if the USs are presented at very brief durations, but reliable EC effects can be observed at longer US exposure durations. As there were no differences between trace and delay conditioning, the data suggest that contingency awareness plays a crucial role in trace and in delay conditioning of evaluative responses. These results challenge automatic association-formation accounts of EC, but they are in line with ‘single-process’ accounts assuming EC to be dependent on conscious declarative knowledge about CS–US contingencies.     

Asymmetrical effects of Pavlovian excitatory and inhibitory aversive transfer on Pavlovian appetitive responding and acquisition

Predictions of a theory of Pavlovian motivational transfer, which incorporates principles of both the theory of reciprocal inhibition and the Rescorla-Wagner model, were tested in several Pavlovian aversive to Pavlovian appetitive transfer tasks. As predicted, the presence of a signal for an aversive event, conditioned stimulus (AV CS+), reliably suppressed performance of appetitive conditioned responses (CRs) whether imposed during acquisition or on independently established responding. Acquisition of appetitive responding to a novel CS reinforced in compound with an AV CS+, however, was enhanced (“superconditioning”). This observation suggests that the effects of a discrepancy between expectation and actual outcome on a conditioning trial are influenced by the affective value of both the expectation and the reinforcer. These transfer effects were not symmetrical for an inhibitory aversive stimulus (AV CS?). An AV CS? did not enhance appetitive responding compared to a random control condition, nor did the AV CS? reduce (i.e., block) appetitive conditioning to a novel CS when appetitive reinforcement occurred in the presence of the AV CS?. Comparison of the two shock-exposed conditions with a naive control condition suggests that previous results that were apparently consistent with inhibitory aversive enhancement and blocking of appetitive conditioning may have been due to aversive context conditioning.     

Evaluative conditioning is pavlovian conditioning: issues of definition, measurement, and the theoretical importance of contingency awareness

In her commentary of Field (1999), Hammerl (1999) has drawn attention to several interesting points concerning the issue of contingency awareness in evaluative conditioning. First, she comments on several contentious issues arising from Field's review of the evaluative conditioning literature, second she critiques the data from his pilot study and finally she argues the case that EC is a distinct form of conditioning that can occur in the absence of contingency awareness. With reference to these criticisms, this reply attempts to address Hammerl's comments by exploring the issues of how awareness is defined, how it is best measured, and whether it is reasonable to believe that EC uniformly occurs in the absence of contingency awareness. The article concludes that the available evidence supports Field's proposition that EC is, in fact, Pavlovian learning. Copyright 2000 Academic Press.     

Event representation in Pavlovian conditioning: image and action

In a typical Pavlovian conditioning experiment, a relatively insignificant event, the conditioned stimulus (CS), is paired with a biologically more meaningful event, the unconditioned stimulus (US). As a consequence of those pairings, the CS is thought to acquire response characteristics of the US. In this article I describe experiments with rats that suggest that under some circumstances, the CS acquires control of perceptual processing of the US, in the absence of that US itself. I present three kinds of evidence for this surrogate processing, which I liken to imagery or hallucination: (1) CSs come to control specific, sensory-evaluative responses normally evoked only by the USs; (2) CSs can substitute for USs in the establishment of new learning about those USs themselves; (3) CSs can substitute for USs in the modulation of conditioning to other events, either overshadowing (interfering) or potentiating learning, in the same manner as the USs themselves. Finally, I compare these data with evidence for conditioned sensation and imagery in humans, and suggest that imagery may be a very basic process, evolutionarily derived from perceptual and conditioning processes adapted to deal with remote or absent objects.     

Reflections on human Pavlovian decelerative heart-rate conditioning with negative tilt as US: alternative approaches.

The negative-tilt preparation that has been reported since the late seventies is a specific form of Pavlovian conditioning that is of scientific interest and has potential applications. In this paper I reflect on the usefulness, to the development of this preparation, of two approaches to Pavlovian conditioning. One approach is the older S-R learning, stimulus-substitution paradigm exemplified by learning texts of the sixties. The other is the modern, Tolman-like view, according to which the phenomenon of Pavlovian conditioning is "now described as the learning of relations among events so as to allow the organism to represent its environment." The three assumptions encapsulated by this approach are: (a) that only CS-US contingency relations are learned; (b) that teleological modes of explanations are adequate; (c) that the representational theory of knowledge is sound. Concerning Pavlovian conditioning in general, questions been raised in the literature for all three assumptions; they have not been adequately answered. Regarding the specific problem of developing the human Pavlovian heart-rate decelerative conditioning with negative tilt as the US, I suggest that the cognitive approach has been much less helpful than the older, S-R, stimulus-substitution paradigm. Nevertheless, other literature clearly indicates that the cognitive, S-S approach has generated considerable interest and research, especially in preparations like the conditioned emotional response (CER), which are CS-IR ones in the sense that the effects on the CR are assessed indirectly through measuring an indicator or instrumental response (IR).(ABSTRACT TRUNCATED AT 250 WORDS)     

A randomized controlled trial of the effect of D-cycloserine on extinction and fear conditioning in humans

Previous research has shown that D-cycloserine (DCS) facilitates extinction of Pavlovian fear conditioning in rats and enhances exposure therapy in humans. The aim of this study was to test the effect of DCS on extinction of fear conditioning in humans. In three experiments, 238 participants were given either DCS (50 or 500 mg) or placebo 2-3 h before extinction training following a differential shock conditioning paradigm. Clear extinction and recovery (return of fear) effects were observed on both skin conductance and self-reported shock expectancy measures in three studies. DCS had no influence on these effects. The same pattern was observed when the analysis was restricted to aware participants or to good conditioners, when fear-relevant cues (pictures of snakes) were used as the conditioned stimuli, or when analysis was restricted to heightened snake-fearful participants. These results suggest that DCS may not enhance the extinction, or prevent the recovery, of learned fear in a differential Pavlovian conditioning paradigm in humans. Further experimental research is needed to better understand the mechanisms underlying the therapeutic effects of DCS.     

Evaluative conditioning can be modulated by memory of the CS–US pairings at the time of testing

Evaluative conditioning (EC) is the valence change of a (typically neutral) stimulus (CS) that is due to the previous pairing with another (typically valent) stimulus (US). It has been repeatedly shown that EC effects are stronger or existent only if participants know which US was paired with which CS. Knowledge of the CS–US pairings is usually measured temporally close to both the conditioning phase and the CS valence measurement phase. Hence, the relation between EC and knowledge about the pairings could indicate either that participants need to become aware of the pairings at some point or that they need to remember them during the CS valence test. We isolated the impact of memory during the CS valence test in a study that encompassed two sessions. During the first session, participants were presented with CS–US pairings. The valence of the CSs was measured in a second session several days later using both a rating scale and an affective priming procedure. Memory for the pairings was measured both during the first and the second session. Using item-based multilevel analysis, we found that EC in the second session was related to memory for the pairings during the second session, but not to the memory for the pairings measured immediately after the learning phase. For the pairs that were remembered during the first session, but not during the second session, no EC effect was found. These results suggest that memory for CS–US pairings during valence measurement can be relevant for EC effects to occur.     

Where is the chocolate? Rapid spatial orienting toward stimuli associated with primary rewards

Some stimuli can orient attentional resources and access awareness even if they appear outside the focus of voluntary attention. Stimuli with low-level perceptual salience and stimuli with an emotional content can modulate attention independently of voluntary processes. In Experiment 1, we used a spatial cuing task to investigate whether stimuli that are controlled for their perceptual salience can modulate the rapid orienting of attention based exclusively on their affective relevance. Affective relevance was manipulated through a Pavlovian conditioning paradigm in which an arbitrary and affectively neutral perceptual stimulus was associated with a primary reward (i.e., a chocolate odor). Results revealed that, after conditioning, attentional resources were rapidly oriented toward the stimulus that was previously associated with the reward. In Experiment 2, we used the very same conditioning procedure, but we devaluated the reward after conditioning for half of the participants through a sensory-specific satiation procedure. Strikingly, when the reward was devaluated, attention was no longer oriented toward reward-associated stimuli. Our findings therefore suggest that reward associations rapidly modulate visual processing independently of both voluntary processing and the perceptual salience of the stimulus. This supports the notion that stimuli associated with primary rewards modulate rapid attention orienting on the basis of the affective relevance of the stimulus.