Temporal summation of pain from radiant stimulation

Latency thresholds of pricking pain, using radiant thermal stimulation, were obtained. Ten Ss were tested for 10 sessions, and, in each session, single latency determinations were made at each of 10 stimulus intensities. Each intensity was administered to a different spot along the volar surface of S’s nonpreferred forearm. Thus, 10 latency thresholds were obtained from each S at. each intensity and each spot. Initial skin temperature was controlled so that a threshold determination was made when skin temperature measured 33.5° ± 0.5° C. Analysis of variance of the log₁₀ t (seconds) values revealed a highly significant linearity of regression of log t on log intensity, thus confirming the hypothesized inverse and exponential relationship between latency and intensity. The parameters (slope and x-intercept) of the curve were discussed. The x-intercept may be interpreted as an index of an aversive threshold and could be used as a possible measure of the physiological component of pain.     

Reaction time as a function of stimulus intensity for the monkey

Monkeys were trained to release a telegraph key in response to a visual or auditory stimulus. The latency of the key release response was measured for different stimulus intensities. In general, the relation between latency and intensity is inverse and exponential with greater variability of latency at the lower intensities. Some preliminary data involving differential reinforcement of short latencies are presented.     

The reliability of an extrapolated measure of an aversive threshold of pain from radiant stimulation

The relationship between the logarithm of pain threshold latency (sec) and the logarithm of the stimulus intensity (mcal/cm²/sec) has been shown to be linear, and the extrapolated x-intercept value of the linear equation could be a useful measure in pain research. In order to assess the reliability of the x-intercept, pain latency thresholds, were obtained from 23 Ss by utilizing the D’Amour-Smith modification of the dolorimetric technique and by testing under a variety of conditions at each of four stimulus intensities. The empirically determined log t (sec) values were shown to be slightly, but significantly, higher when stimulation was applied to either the dominant limb or to the legs rather than to the nondominant limb or to the arms. The computed slope and x-intercept values did not differ between limbs or between dominant and nondominant sides. None of the three measures changed significantly between the two sessions. The x-intercept value was interpreted as an index of a threshold of aversion and its meaning and applicability were discussed.     

Inhibition of acoustic startle using different mechanoreceptive channels

In this experiment, we investigated the impact of vibrotactile prepulse frequency and intensity on the acoustically elicited startle response in humans. Mechanoreceptive channels differing in their sensitivity to transient stimulation have been identified in the skin. The Pacinian channel is optimally sensitive to vibrations at approximately 300 Hz and is specialized for the detection of stimulus transients, whereas the non-Pacinian I and III channels are optimally sensitive to vibrations at approximately 30 Hz. Vibrotactile prepulses with frequencies of 30 and 300 Hz and intensities of 95 and 130 mV were presented for 50 msec to the dominant hand of college students (N = 31), followed on some trials by a 95-dB broadband acoustic startle stimulus. The 300-Hz prepulses resulted in significantly more pronounced inhibition of startle magnitude, amplitude, and probability, whereas only the 30-Hz prepulses significantly facilitated blink latency. These results support the idea that the inhibition of acoustic startle is determined more by transient than by sustained aspects of vibrotactile prepulse stimuli. This study also demonstrates that different aspects of the startle response differentially reflect stimulus characteristics of the prepulse.     

Long latency auditory evoked potentials

Experiment 1 elicited the P1, N1, P2, and N2 components of the long latency auditory evoked potential (AEP) using a 1000 Hz tone presented at 30, 50, or 70 dB SPL and 1-, 3-, or 5- second inter-stimulus intervals to assess the relative effects of the combination of these variables on component amplitude and latency. Four blocks of 16 tone presentations each were recorded from each subject to determine if changes in the AEP would occur because of short-term habituation. Both stimulus factors interacted significantly in a systematic fashion for the amplitude measures, with increases in latency also associated with increases in intensity and inter-stimulus interval. Only minor changes across the four trial blocks for either the amplitude or latency measures were observed over the various stimulus presentation conditions. Experiment 2 employed the same tone stimulus presented at 50 dB SPL and a 3-second inter-stimulus interval. Eight blocks of 64 trials were recorded from each subject on each day for four days to investigate long-term habituation effects. No substantial changes in any of the component amplitudes or latencies were obtained across the 32 trial blocks. It was concluded that intensity and inter-stimulus interval interact to determine AEP amplitude as well as latency values and that the constituent components do not change appreciably with repeated stimulus presentations, even after several days.     

The role of small changes in the acoustic environment in modifying the startle reflex.

When either the intensity or frequency spectrum of an approximately 70-db. SPL narrow-band noise was abruptly changed by a small amount, the rat's response to a startle stimulus presented 64 msec later was inhibited. When similar small frequency changes preceded the startle stimulus by ony 5 msec, the latency of the startle response was reduced, but even relatively large changes in intensity of the antecedent stimulus had no effect on response latency. These findings provide added support for the generalization that the neural processes associated with startle are engaged by small changes in the auditory environment. They also point to a measure of separation between the processes responsible for inhibition and those responsible for latency shift.     

On the discriminative control of concurrent responses: the relations among response frequency, latency, and topography in auditory generalization

Human subjects were used in a study of auditory generalization following multiple-response discrimination training. The relations observed among stimulus intensity, response probability, and response latency were invariant with respect to whether the two vocal responses conditioned were topographically discrete, as in one experiment, or topographically continuous, as in another. The major findings were:

1. The probabilities associated with a specific response were maximal over several stimulus values at the extreme ends of the continuum, then dropped sharply at stimuli intermediate to the initial S^D's as the probability of the alternative response increased.

2. Overall response latency was inversely related to the relative frequency of the two responses at each stimulus value. When the two responses were most nearly equal in probability, latencies were maximal; when one response had close to unit or zero probability, latencies were minimal.

3. Analysis of the latencies of the two responses, taken separately, revealed: (a) an increase in latency as the difference between the test stimulus and the initial S^D increased; (b) a sharp discontinuity in the latency gradient and reversal in trend at intermediate stimulus intensities; and (c) at a given stimulus value, latencies associated with the stochastically dominant response were consistently shorter than those of the nondominant response.

4. No changes in response topography (fundamental frequency) were correlated with the characteristic changes in probability and latency during stimulus generalization.

     

A double-response paradigm to study stimulus intensity effects upon the motor system in simple reaction time experiments

A double response paradigm is utilized to study stimulus intensity effects upon the motor system in simple visual and auditory reaction times (RT). Subjects had to respond with both hands simultaneously upon detection of a stimulus. The RT difference of both hands is thereby of special interest, because it is considered that this variable does not contain any sensory latency and therefore allows one to study those processes that follow stimulus detection. It was found that the RT-difference distribution varies with stimulus intensity, which questions the general view that stimulus intensity affects only very early sensory stages in the processing chain. In particular, it was found that the variance of RT difference diminished with increasing stimulus intensity. This finding supports the notion of speeding up the motor process by increasing stimulus intensity. A generalization of a stochastic model by Meijers and Eijkman (1974) and Meijers, Teulings, and Eijkman (1976) is advanced to account for the findings. The central assumption is that more units (e.g., motoneurons) are activated if stimulus intensity is increased. The model’s qualitative predictions are confirmed.     

Perceptual latency priming: A measure of attentional facilitation

The present paper reviews recent research on perceptual latency priming (PLP). PLP is the relative latency advantage-earlier perception-of a visual stimulus that is preceded by another, masked stimulus at its location. The first stimulus attracts attention which accelerates perception of the second stimulus. This facilitation arises even if the first stimulus is visually backward-masked by the second one. The paper summarises research on temporal and spatial properties of PLP and the question whether intentions mediate shifts of attention to external events. Possible sources of PLP besides visuo-spatial attention are discussed. Finally, I give a review of feedforward and reentrant models of PLP and compare them to the empirical evidence.     

Generalization and response latency

The present experiments investigated generalization in a reaction time situation where the generalization stimulus, a tone, preceded the reaction time signal, a light. The hypotheses under investigation were that the duration of the cue stimulus would determine the degree of generalization (Experiment I) and that the response latency independent of the stimulus duration would be related to the amount of generalization (Experiment II). A particular generalization test stimulus (a tone of 40, 45, 50, 60, 65, or 70 dB) was presented only once always following two bar-pressing responses to training stimulus (tone of 55 dB) under each of two conditions of stimulus duration in Experiment I and under each of two conditions of response latency in Experiment II. It was found that under the condition of short response latency generalization was broader.     

Generalization and response latency

The present experiments investigated generalization in a reactio? time situation where the generalization stimulus, a tone, preceded the reaction time signal, a light. The hypotheses under investigation were that the duration of the cue stimulus would determine the degree of generalization (Experiment I) and that the response latency independent of the stimulus duration would be related to the amount of generalization (Experiment II). A particular generalization test stimulus (a tone of 40, 45, 50, 60, 65, or 70 dB) was presented only once always following two bar-pressing responses to training stimulus (tone of 55 dB) under each of two conditions of stimulus duration in Experiment I and under each of two conditions of response latency in Experiment II. It was found that under the condition of short response latency generalization was broader.     

Saccade latency and warning signals: Stimulus onset,offset, and change as warning events

Two experiments investigated saccade latency to a peripheral target under various warning signal conditions. In Experiment I, the effects of warning stimulus onset, change, and two offset conditions were compared at warning intervals of 0, 100, 300, and 600 msec. Warning stimulus onset, change, and offset were all effective in reducing saccade latency as compared to a no-warning control condition, but warning stimulus offset resulted in shorter saccade latency than onset or change at all warning intervals. Experiment 2 compared onset and offset warning conditions at ?300-, ?250-, ?200-, ?150-, ?100-, ?50-, 0-, and 50-msec intervals. Responses following onset were slower than those following offset at the latter five intervals, while warning onset resulted in slower saccades than no-warning control conditions at ?150-, ?100-, and ?50-msec intervals. These results indicate that the onset of a visual warning signal can have an interfering effect on the programming or execution of a saccade.     

Discrimination by newborns of the intensity, frequency and temporal characteristics of auditory stimuli

The ability of 3- to 5-day-old neonates to discriminate between auditory stimuli, in terms of each of the dimensions of intensity, pitch and time, was studied using heart-rate responses in a habituation paradigm. For each of the dimensions a survey of the literature failed to provide results which could be used as the basis for later work involving auditory patterns. Further analysis of an earlier experiment (Stratton, 1970 a) involving stimuli at 80, 85 and 90 db showed that louder stimuli evoked larger initial responses and more rapid habituation. From the same experiment it was found that a change of pitch produced dishabituation as early as the 10th trial. There are reasonable grounds for attributing the increased response to the frequency characteristics rather than a change in the perceived intensity of the stimuli. Previous experiments suggested that fixed inter-stimulus intervals tended to produce anticipatory heart-rate changes and modify the magnitude and latency of the response. Two experiments designed specifically to examine temporal phenomena revealed time-linked behaviour. In both experiments acceleratory responses occurred at the first stimulus omission of a fixed-interval series. Not all of the subjects showed this effect, and in both experiments, only the subjects who failed to respond to the first stimulus presentation responded to stimulus omission. The findings are discussed in relation to general issues of neonatal psychophysiology, and it is concluded that neonates can discriminate in each of the auditory dimensions, but that preliminary work involving patterns should concentrate on varying pitch and intensity.     

Vibrotactile difference thresholds for intensity and the effect of a masking stimulus

Vibrotactile difference thresholds for intensity were measured at several intensity levels of a test stimulus in the absence of a masking vibration and in the presence of three different amplitudes of a masking vibration. The test stimulus was a 160-Hz vibration delivered to the right index finger. The masking stimulus was a 160-Hz vibration delivered to the right little finger. For the same amplitudes of the test stimulus, △I varied as a direct function of the amplitude of the masking vibration. The smallest △Is resulted from measurements made in the absence of the masking stimulus. The Weber fraction, △I/I, was constant only for the more intense test stimuli in the absence of any masking stimuli. Independent of the presence or level of the masker, the Weber fraction for all stimuli approached approximately the same value, .25, when the test stimuli were raised to 20-dB sensation level. A model is proposed to account for the increase in the Weber fraction as a function of masker intensity and to predict masked thresholds.     

A study of the near-miss involving Weber’s law and pure-tone intensity discrimination

A study of pure-tone intensity discrimination is presented in which amplitude changes are detected in 1000 Hz tone bursts 15–20 msec in duration. The masking function (log detectable increment vs log background intensity) is found to have a slope of 9/10 when calculations are carried out via energy measurements. This near-miss to Weber’s law is in agreement with other data reported in the literature. The masking slope proves to be essentially independent of stimulus duration between 15 msec and 1.5 sec. Our stable slope parameter is interpreted as a detectability restriction generated by “mass-flow” phenomena in the auditory channel. These phenomena are thought to be similar to the fluctuations accompanying a noisy or turbulent stream of events. Pure-tone intensity discrimination is then analyzed as a special case of energy detection.     

Choice as a dependent measure in autoshaping: sensitivity to frequency and duration of food presentation.

Previous investigations have shown that rate, latency, and percentage of trials with at least one response are somewhat insensitive measures of the strength of autoshaped responding. In the present studies, these measures were contrasted with the allocation of responding during simultaneous choice tests, a measure of response strength frequently used in operant paradigms. In two experiments, nine pigeons were exposed to a forward pairing autoshaping procedure. Training sessions consisted of the successive presentation of three stimuli, each followed by food on either 100%, 50%, or 0% of the trials. Choice testing involved the simultaneous presentation of the three stimuli. In Experiment I, all pigeons consistently directed their initial choice responses and the majority of subsequent responses to the stimulus always followed by food, despite the fact that during training sessions the response rates of most birds were highest in the presence of the stimulus followed by food on 50% of the trials. In Experiment II, rate, latency, and percentage of trials with at least one response did not change appreciably as a function of duration of feeder presentations. However, choice responding was lawfully affected by duration of feeder presentations. These data suggest that choice is perhaps a more sensitive measure of the strength of autoshaped responding than other, more commonly employed, indices.     

Escape behavior under different fixed ratios and shock intensities

The effects of ratio length and shock intensity on bar pressing were examined in three rats in two escape-from-shock experiments. In Experiment I, shock intensity was held constant while the schedule was varied from FR 1 to FR 20. The latency of the first escape response increased with FR length while the escape rate, computed as over-all rate in shock minus latency of the first response, decreased at FR 20. In Experiment II, the schedule was held constant at FR 5 while shock intensity was manipulated. Latency decreased as intensity increased, while escape rate increased with intensity, passing through a maximum for two subjects. Responses occurring during the last 100 sec of the 2-min escape period decreased as the FR increased for all subjects, and decreased as shock intensity increased for two subjects.     

Personality and the topography of the conditioned eyelid response

One-hundred and four women were tested on an eyelid conditioning paradigm in a 2 x 2 x 2 factorial design where two levels of US intensity (1 vs 3 p.s.i.) were balanced against two rest pause interpolations (after 25 and after 50 trials), and the presence or absence of a warning stimulus prior to CS-US presentation. Subjects were later classified as high, low or intermediate extraverts on the basis of a personality questionnaire. A very detailed analysis of conditioned responses was carried out, using both simple and composite measures including work-ratio, utility-ratio, CR frequency, peak latency, peak amplitude, response area and effective response area, degree of avoidance amplitude and latency, etc. Major findings related to similar effects of high intensity US vs low intensity US, and introversion vs extraversion; introverts react as if they were responding to more intense stimuli than extraverts. This finding cuts across other parameter variables, and supports Eysenck's formulation of personality-conditioning relationships in terms of higher cortical arousal in introverts as compared with extraverts.     

SENSORY AND PREPARATORY FACTORS IN RESPONSE LATENCY

T hrane , V. C. Sensory and preparatory factors in response latency. V. Stimulus blanks as regulator of preparatory set. Scand. J. Psychol ., 1962, 3 , 1–15.—When otherwise nearly replicating the preceding experiment, but excluding the final reaction signal in 14 per cent of the trials under all conditions, response latency was much less affected, if at all, by differential warning of stimulus strength. It is concluded that a constant proportion of stimulus blanks serves largely to equalize perceptual uncertainty on the part of the respondent as to presence of a stimulus, in spite of variations in the sensory adequacy of the expected stimulus, and hence may be used when necessary as an antecedent variable for generating more comparable preparatory sets in studies concerned with the sensory effects of stimulus variables.     

Variability and sequential effects in cross-modality matching of area and loudness

Individual subjects' performance was examined for cross-modality matching (CMM) of loudness to visual area, as well as for magnitude estimation (ME) of the component continua. Average exponents of power functions relating response magnitude to stimulus intensity were .73 for area, .20 for loudness, and 2.44 for CMM. Predictions of the CMM exponent based on ME were higher than the empirical values, whereas more accurate predictions were made from magnitude production exponents obtained in a previous study. Sequential dependencies were assessed by comparing the response on trial n to the response on trial n--1. The coefficient of variation of the response ratio Rn/Rn-1 was systematically related to the stimulus ratio Sn/Sn-1 for both area and loudness. The coefficient was lowest for ratios near 1 and increased for larger or smaller values. For CMM, the coefficient of variation appeared to be independent of stimulus ratios. The correlation between log Rn and log Rn-1 was also related to Sn/Sn-1 for both ME and CMM. The correlation was highest when Sn/Sn-1 was 1 and dropped to 0 with increasing stimulus separation, but CMM yielded a shallower function than ME.