Event-related potentials indicate that reality monitoring differs from external source monitoring

This experiment investigated differences in event-related potentials (ERPs) observed in 2 types of source monitoring decisions. Participants discriminated between self-generated, heard, and new words (reality monitoring) in one condition; in another they discriminated between words heard in a male or female voice and new items (external source monitoring). The data support the source monitoring framework, which argues that reality monitoring discriminations differ from external source monitoring discriminations. Analysis revealed better overall source accuracy during reality monitoring than during external source monitoring. In the external source monitoring task, an early old-new ERP difference was observed at parietal electrodes followed by frontal old-new effect that persisted longer, replicating previous ERP results. However, early ERP amplitude differences between sources were observed at parietal electrode sites during reality monitoring, suggesting that self-generated items activate more differentiated information during remembering. Furthermore, there were no frontal old-new ERP differences during reality monitoring, suggesting that different decision processes are used in these types of source monitoring decisions.     

APT PC and APT II: Experiment development systems for the IBM PC and Apple II

Systems for creating and running psychology experiments on an Apple II or IBM PC are described. Without programming, psychologists using the APT systems can construct and conduct an experiment, summarize the data, and revise the experiment. The systems are easily used by students but powerful enough to be used by psychologists in their research.     

Neuroscientific Measures of Covert Behavior

In radical behaviorism, the difference between overt and covert responses does not depend on properties of the behavior but on the sensitivity of the measurement tools employed by the experimenter. Current neuroscientific research utilizes technologies that allow measurement of variables that are undetected by the tools typically used by behavior analysts. Data from a specific neuroscientific technique, event-related potential (ERP), suggest that emission of otherwise covert responses can be indexed and that such covert responses are sensitive to stimulus control and selection by consequences. The P3 ERP effect is proposed as indicative of emission. Moreover, ERP results in semantic priming experiments suggest that operants are sensitive to changes in stimulus control even when they are not emitted (latent responses). Changes in response strength of latent responses as a function of stimulus control can in fact be measured by reaction time data and an ERP dependent variable called the N400 effect. If the interpretations provided in this paper are accurate, an index of covertly emitted operants (P3 effect) constitutes experimental evidence suggesting the validity of a Skinnerian radical behaviorist perspective on behavior. Moreover, in a Skinnerian paradigm, measured fluctuations in the response strength of latent operants as a function of environmental changes (N400 effect) would validate Palmer's (2009) concept of the repertoire.     

Issues in the application of the average reference: Review, critiques, and recommendations

In standard event-related potential (ERP) recordings, activity at the reference site affects measurements at all the “active” electrode sites. Analyses of ERP data would be improved if reference site activity could be separated out. Apart from current source density methods, which can miss deep or distributed events, the major alternative to an “indifferent” electrode reference is one that combines all active electrodes, subtracting out the activity common to all of them. The average reference has merits (such as an insensitivity to scalp currents near any single electrode) and limitations (such as a dependence on the number and locations of all the electrodes in the average). This review compares the effects of different references on the scalp topography of the auditory N1 recorded with an array of 128 electrodes. Furthermore, it shows how assumptions associated with each reference affect inferential methods such as analysis of variance and correlation. Finally, it seeks to evaluate the efficacy of the average reference in estimating the true zero potential line.     

负性情绪调节中认知重评和分心策略的作用:ERPs研究

采用事件相关电位技术,考察了认知重评和分心两种情绪调节策略对负性情绪体验和脑电活动的影响。结果发现,认知重评后被试的负性情绪体验强度和LPP波幅(300~1300ms)比简单注视条件下低;分心后被试的负性情绪体验强度比简单注视条件下低,但LPP波幅显示比简单注视条件下高。这说明认知重评和分心对负性情绪体验和脑电活动的影响不同,负性刺激再次呈现时认知重评优于分心策略的调节。该研究为认知重评和分心的比较研究提供了神经电生理学方面的证据。     

Experimental control and data acquisition with BASIC in the Apple computer

Laboratory experiments can be precisely controlled and data can be collected using the BASIC language on an Apple II+ computer with 48-KB RAM, disk drive, and two timer-I/O cards. The Apple BASIC makes machine language output control routines necessary, but quite convenient. By compiling BASIC, 50–100 inputs/sec are handled. Applications range from operant research and analog data collection to use of the Apple color display capability for stimulus presentations and response recording.     

D-Cycloserine for Treatment Nonresponders With Obsessive-Compulsive Disorder: A Case Report

Despite being the most effective treatment available, as many as one third of patients who receive exposure and response prevention (ERP) for obsessive-compulsive disorder (OCD) do not initially respond to treatment. Recent research suggests that the n-methyl d-aspartate (NMDA) receptor partial agonist D-Cycloserine (DCS) may speed up the course of ERP for OCD rather than enhance it. Thus, it is unclear whether DCS would benefit patients who have proven nonresponsive to ERP and serotonin reuptake inhibitors. The present study evaluated the ability of DCS to enhance ERP for 2 patients with OCD who previously had failed to show adequate response to treatment using time-series analysis. Both patients experienced greater reductions with DCS augmented ERP than they did with prior treatment; however, 1 patient relapsed by the 1-month follow-up. DCS augmented ERP might be an effective method for boosting outcomes in individuals who do not readily respond to ERP.     

A microcomputer package for real-time skin conductance response analysis

A suite of programs has been developed to acquire data from a commercially available, highquality skin conductance meter, via a standard IEEE bus, on an Apple II or Apple lie microcomputer. These programs score and analyze stimulus-evoked skin conductance responses in a preset time window, and store the resultant data on disk, if required. Facilities for a manual override of the automatic scoring routine are available. The setup offers a method of scoring data as they are acquired; it uses currently recommended standards for skin conductance analysis and allows a high magnification of responses, without any need for continual monitoring, because of hardware facilities that automatically “back-off” a subject’s tonic skin conductance level.     

Prosodic boundaries, comma rules, and brain responses: the closure positive shift in ERPs as a universal marker for prosodic phrasing in listeners and readers

Just as the false comma in this sentence, shows punctuation can influence sentence processing considerably. Pauses and other prosodic cues in spoken language serve the same function of structuring the sentence in smaller phrases. However, surprisingly little effort has been spent on the question as to whether both phenomena rest on the same mechanism and whether they are equally efficient in guiding parsing decisions. In a recent study, we showed that auditory speech boundaries evoke a specific positive shift in the listeners' event-related brain potentials (ERPs) that indicates the sentence segmentation and resulting changes in the understanding of the utterance (Steinhauer et al., 1999a). Here, we present three ERP reading experiments demonstrating that the human brain processes commas in a similar manner and that comma perception depends crucially on the reader's individual punctuation habits. Main results of the study are: (1) Commas can determine initial parsing as efficiently as speech boundaries because they trigger the same prosodic phrasing covertly, although phonological representations seem to be activated to a lesser extent. (2) Independent of the input modality, this phrasing is reflected online by the same ERP component, namely the Closure Positive Shift (CPS). (3) Both behavioral and ERP data suggest that comma processing varies with the readers' idiosyncratic punctuation habits. (4) A combined auditory and visual ERP experiment shows that the CPS is also elicited both by delexicalized prosody and while subjects replicate prosodic boundaries during silent reading. (5) A comma-induced reversed garden path turned out to be much more difficult than the classical garden path. Implications for psycholinguistic models and future ERP research are discussed.     

“Phobie à deux” and other reasons why clinicians do not apply exposure with response prevention in patients with obsessive–compulsive disorder

Meta-analyses suggest that exposure with response prevention (ERP) is the most efficacious treatment for obsessive–compulsive disorder (OCD) and treatment guidelines for the disorder accordingly recommend ERP. Despite this, many therapists, including those with a cognitive-behavioral therapeutic background, do not perform ERP in patients with OCD. The present study aimed to elucidate the reasons why. German therapists (N = 216) completed an anonymous online survey, the newly developed Reasons for Not Performing Exposure in OCD Scale (REPEX), that inquired whether, to what extent, and how they perform ERP in the treatment of OCD. We also asked their reasons for not applying ERP in the past. Most therapists considered ERP an efficient treatment for OCD. Marked differences emerged between physicians and psychologists, however. The former used exposure less often and for a shorter period, preferred in sensu to in vivo exposure, and conducted exposure less often in the personal environment of the patient than did psychologists. Both groups were familiar with clinical guidelines to a similar extent. A factor analysis of the REPEX scale revealed five factors. Patient lack of motivation, preference for exposure to be self-help as well as alleged organizational difficulties were endorsed most often. The latter was correlated with the age of the therapist and was far more often affirmed by physicians. Fear of side effects was named by a subgroup of clinicians; in the context of patient ambivalence, this may foster “phobie à deux”. Unlike prior research, lack of expertise was rarely identified as a reason not to use ERP. Recommendations for improving adherence to guidelines are discussed.     

On the early left-anterior negativity (ELAN) in syntax studies

Within the framework of Friederici’s (2002) neurocognitive model of sentence processing, the early left anterior negativity (ELAN) in event-related potentials (ERPs) has been claimed to be a brain marker of syntactic first-pass parsing. As ELAN components seem to be exclusively elicited by word category violations (phrase structure violations), they have been taken as strong empirical support for syntax-first models of sentence processing and have gained considerable impact on psycholinguistic theory in a variety of domains. The present article reviews relevant ELAN studies and raises a number of serious issues concerning the reliability and validity of the findings. We also discuss how baseline problems and contextual factors can contribute to early ERP effects in studies examining word category violations. We conclude that - despite the apparent wealth of ELAN data - the functional significance of these findings remains largely unclear. The present paper does not claim to have falsified the existence of ELANs or syntax-related early frontal negativities. However, by separating facts from myths, the paper attempts to make a constructive contribution to how future ERP research in the area of syntax processing may better advance our understanding of online sentence comprehension.     

A brief introduction to the use of event-related potentials in studies of perception and attention

Because of the precise temporal resolution of electrophysiological recordings, the event-related potential (ERP) technique has proven particularly valuable for testing theories of perception and attention. Here, I provide a brief tutorial on the ERP technique for consumers of such research and those considering the use of human electrophysiology in their own work. My discussion begins with the basics regarding what brain activity ERPs measure and why they are well suited to reveal critical aspects of perceptual processing, attentional selection, and cognition, which are unobservable with behavioral methods alone. I then review a number of important methodological issues and often-forgotten facts that should be considered when evaluating or planning ERP experiments.     

A simple infrared photocell device and its interface to an Apple computer

This paper describes a simple infrared photocell circuit that is inexpensive and easy to construct. The light source and detector are housed inexpensively and are focused so the light and detector may be separated over significant distances. The circuit may be used in a variety of conditions, including total darkness and bright fluorescent lighting, without having to readjust or recalibrate the circuitry. Output from the circuit may be used to drive other transistors or electromechanical relays. With minimal additional circuitry and hardware the signal may be interfaced with an Apple computer.     

汉语母语者英语动词三种屈折变化形式加工机制的差异

采用ERP技术考察了汉语母语者,英语动词三种屈折变化形式加工机制的差异。结果发现,英语动词进行式的屈折变化形式- ing的错误使用诱发了P600成分;完成式的屈折变化形式- ed的错误使用诱发了N400成分;完成式中没有明显屈折变化标识的不规则词的错误使用没有诱发典型的ERP成分。研究结果表明：对于缺乏英语使用环境、母语为汉语的晚期英语学习者来说,屈折变化形式- ing,完成式规则动词的变化形式- ed和没有明显形态变化标识的不规则动词的变化形式具有不同的加工机制,前者可能处于由陈述性记忆系统向程序性记忆系统加工的转变过程中,而后两者更多地由陈述性系统进行加工。这种加工机制的差异可能与动词屈折变化规则的复杂程度有关。     

To watch, to see, and to differ: an event-related potential study of concreteness effects as a function of word class and lexical ambiguity

Electrophysiological techniques were used to assess the generalizability of concreteness effects on word processing across word class (nouns and verbs) and different types of lexical ambiguity (syntactic only and combined syntactic/semantic). The results replicated prior work in showing an enhanced N400 response and a sustained frontal negativity to concrete as compared with abstract nouns. The effect of concreteness on the N400 generalized to all word class and ambiguity conditions, whereas the frontal effect was present for all word types except for the syntactically and semantically ambiguous items when these were used as verbs. The seemingly dissociable ERP effects of concreteness at frontal and central/posterior electrode sites revealed by these data suggest that concreteness may impact multiple aspects of neurocognitive processing.     

Digital filtering in EEG/ERP analysis: Some technical and empirical comparisons

A general approach to time domain digital filtering is described, and examples of some filters used in EEG/ERP research are presented. Simulations are reported that evaluate the impact of the relative length of the filter weight series and the signal cycle to be filtered, the span and real-time density of the filter weights, and slow drift across the epoch being filtered. Results indicate that some filters commonly used in the EEG/ERP literature are inadequate. Frequency domain digital filtering is also briefly discussed. The fast Hartley transform, a fast but relatively unknown computational method for frequency domain filtering of ERP/EEG data, is introduced and compared with time domain filtering. Some practical recommendations are provided.     

An Apple microcomputer-based laboratory system for the study of visual-motor behavior

An apparatus for studying motor control and visual-motor coordination is described. The system consists of an Apple II+ with two expansions boards installed. One board provides advanced graphics capabilities; the other interfaces the Apple with a digitizing tablet and also provides a real-time clock. Target stimulus and visual feedback concerning self-produced movement (i.e., a cursor) are displayed on a standard video monitor, and movement data are sampled by the digitizing tablet. Software consists of about 3K bytes of assembled 6502 code and a 2K byte Applesoft BASIC program. The system is inexpensive, versatile, and particularly well suited for developmental research. It has been used with human subjects as young as 3 years of age.     

On-line Apple II for the recording and analysis of complex motor movements

The system described here was prompted by the need for a method of separately recording various components of a complex motor act. The task involved vertical, horizontal, and turn components. Our particular interest was the relation between integration of components and level of skill demonstrated. The peripheral equipment provides a separate analogue output for each component and plugs directly into the Apple’s game-paddle input. Trial data are stored directly on disk and can be retrieved for subsequent graphical plotting and analysis. The Apple II accommodates up to four inputs and returns results for movements as fast as .05 sec. The programming system can be used, without modification, for a wide variety of motor tasks. No additional interface or clock is required.     

Psychological Flexibility as Shared Process of Change in Acceptance and Commitment Therapy and Exposure and Response Prevention for Obsessive-Compulsive Disorder: A Single Case Design Study

Changes in psychological flexibility were tracked in a combined protocol of exposure and response prevention (ERP) and acceptance and commitment therapy (ACT) for adults with OCD to assess if changes in psychological flexibility processes were unique to ACT intervention (e.g., not impacted by ERP). Using a nonconcurrent multiple baseline design, four participants received sessions of ERP and ACT while data was collected on psychological flexibility processes of change and OCD symptom severity. Results indicate treatment response for three of four participants based on OCD scores. Contrary to predictions, data suggest both ERP and ACT have positive effects on psychological flexibility. Implications of these findings are discussed in relation to recent research on ACT and ERP for OCD. This study also illustrates a type of research design that can be accomplished in clinical practice.