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1.
There are competing ethical concerns when it comes to designing any clinical research study. Clinical trials of possible treatments for Ebola virus are no exception. If anything, the competing ethical concerns are exacerbated in trying to find answers to a deadly, rapidly spreading, infectious disease. The primary goal of current research is to identify experimental therapies that can cure Ebola or cure it with reasonable probability in infected individuals. Pursuit of that goal must be methodologically sound, practical and consistent with prevailing norms governing human subjects research. Some maintain that only randomized controlled trials (RCTs) with a placebo or standard-of-care arm can meet these conditions. We maintain that there are alternative trial designs that can do so as well and that sometimes these are preferable to RCTs.  相似文献   

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The paper aims at exploring if we have sound philosophical reason to embrace a human right to Internet access. While attempts to make Internet access a candidate for the standing of human right have become popular in both the political and legal arenas, we still lack serious philosophical reflection on this issue. The paper first evaluates the arguments made by various authors, and then moves to provide its own conclusions. Its logic is that if (i) Internet access is crucial for enabling democracy, and (ii) democracy is a basic human right, then we may have at least prima facie reason to see such a technology as a derived human right whose normativity supervenes on the right to democracy.  相似文献   

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A program is described that allows experimenters to generate American Sign Language forms by computer. The computer synthesis of such signs could allow major advances in the experimental investigation of the perception of sign language, much as computer-generated speech has done for the study of speech perception.  相似文献   

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This paper proposes a new argument in favour of the claim that phenomenal consciousness overflows – that is, has a far higher capacity than – cognitive access. It shows that opponents of overflow implicate a necessary role for visual imagery in the change detection paradigm. However, empirical evidence suggests that there is no correlation between visual imagery abilities and performance in this paradigm. Since the use of imagery is not implicated in the performance strategy of subjects, we find a new argument for consciousness without access.  相似文献   

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ABSTRACT— Developmental studies have identified a strong correlation in the timing of language development and false-belief understanding. However, the nature of this relationship remains unresolved. Does language promote false-belief understanding, or does it merely facilitate development that could occur independently, albeit on a delayed timescale? We examined language development and false-belief understanding in deaf learners of an emerging sign language in Nicaragua. The use of mental-state vocabulary and performance on a low-verbal false-belief task were assessed, over 2 years, in adult and adolescent users of Nicaraguan Sign Language. Results show that those adults who acquired a nascent form of the language during childhood produce few mental-state signs and fail to exhibit false-belief understanding. Furthermore, those whose language developed over the period of the study correspondingly developed in false-belief understanding. Thus, language learning, over and above social experience, drives the development of a mature theory of mind.  相似文献   

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Journal of Psycholinguistic Research - An amendment to this paper has been published and can be accessed via the original article.  相似文献   

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右半球语言功能研究概述   总被引:1,自引:0,他引:1  
对大脑右半球功能的研究如今趋于增多。该文介绍了右脑半球语言加工能力研究概况 ,这方面研究将对人脑语言功能的研究提供有益的启发。  相似文献   

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In order to understand the nature of human embryos I first distinguish between active and passive potentiality, and then argue that the former is found in human gametes and embryos (even in embryos in vitro that may fail to be implanted) because they all have an indwelling power or capacity to initiate certain changes. Implantation provides necessary conditions for the actualization of that prior, active potentiality. This does not imply that embryos are potential persons that do not deserve the same respect as actual persons. To claim that embryos become persons is to understand the predicate person as a phase sortal, roughly equivalent to adult person. This entails that we would not be essentially persons. In order to explain the traditional understanding of person as a proper sortal rather than a phase sortal, the author distinguishes between proximate and remote potentiality, and shows that, unlike feline embryos, human embryos, by their genetic constitution, possess the remote potentiality to later exercise the typically human activities. It follows that they are already persons essentially.  相似文献   

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The study of sign languages provides a promising vehicle for investigating language production because the movements of the articulators in sign are directly observable. Movement of the hands and arms is an essential element not only in the lexical structure of American Sign Language (ASL), but most strikingly, in the grammatical structure of ASL: It is in patterned changes of the movement of signs that many grammatical attributes are represented. The "phonological" (formational) structure of movement in ASL surely reflects in part constraints on the channel through which it is conveyed. We evaluate the relation between one neuromotor constraint on movement-regulation of final position rather than of movement amplitude-and the phonological structure of movement in ASL. We combine three-dimensional measurements of ASL movements with linguistic analyses of the distinctiveness and predictability of the final position (location) versus the amplitude (length). We show that final position, not movement amplitude, is distinctive in the language and that a phonological rule in ASL predicts variation in movement amplitude-a development which may reflect a neuromuscular constraint on the articulatory mechanism through which the language is conveyed.  相似文献   

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Classical cognitive science has been characterized by an association with the computational theory of mind. Although this association has produced highly significant results, it has also limited the scope of scientific psychology. In this paper, we analyse the limits of the specific kind of computational model represented by the Chomskian-Fodorian tradition in the study of mind and language. In our opinion, the adhesion to the principle of formality imposed by this specific computational model has motivated the exclusion of consciousness in the reflection on language and, consequently, has led to the inability to account for some aspects of language functioning at the processing level of discourse. The aim of this article is to restore the role of consciousness in discourse comprehension and production processes. Specifically, we argue that the ability to produce and understand discourses is based on individuals’ capacity for navigation in space and time. We will show that the space–time orientation is guaranteed by the projection of the self, which involves a special kind of consciousness.  相似文献   

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Neuropsychological studies suggest that good long-term language outcome is possible following extensive early left-hemisphere damage. We explored the brain organization for language in children with early unilateral lesion, using [15O]-water PET. In 12 patients with left lesion (LL) and 9 patients with right lesion (RL), cerebral blood flow changes during listening to sentences and repetition were studied. A rightward shift of language activations in the LL group was found in perisylvian areas and multiple other, mostly temporo-parietal, regions. The hypothesis of intrahemispheric reorganization in the LL group found only limited support. The number of activated regions was overall greater in the RL group. Unexpected findings included a stronger subcortical and cerebellar language involvement in the RL group. We suggest that (a) early left lesion is associated with enhanced language participation of the right hemisphere in and beyond the classical language areas, and (b) postlesional effects are in part additive (recruitment of noncanonical areas), in part subtractive (functional depression in areas normally involved in language).  相似文献   

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In this paper we present the syntax and semantics of a temporal action language named Alan, which was designed to model interactive multimedia presentations where the Markov property does not always hold. In general, Alan allows the specification of systems where the future state of the world depends not only on the current state, but also on the past states of the world. To the best of our knowledge, Alan is the first action language which incorporates causality with temporal formulas. In the process of defining the effect of actions we define the closure with respect to a path rather than to a state, and show that the non-Markovian model is an extension of the traditional Markovian model. Finally, we establish relationship between theories of Alan and logic programs.  相似文献   

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Consumer susceptibility to salesperson influence (CSSI) is developed as a multidimensional construct and segmentation base for adaptive retail selling strategies. Differences in informational, recommendational and relational CSSI by gender, age, and purchase pal utilization are investigated in a stratified national random sample of new vehicle purchasers. Specific retail and salesperson strategies are discussed.  相似文献   

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This article examines how vignette methodology can aid understanding of cultural identity. This is demonstrated through a study of child language brokers, wherein a child is engaged in the cultural contexts of both the host culture and the home culture and must therefore negotiate new cultural identities. Participants were young people aged 15 to 18 years; some of them were brokers, others were not. Drawing on notions of adequacy and inadequacy, visibility and invisibility, theoretical ideas around cultural identity theory and dialogical self-theory can provide an understanding of how the young people moved through different (often conflicting) identity positions.  相似文献   

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