A microprocessor-based psychopathology laboratory: III. Hardware

The hardware configuration of a psychopathology research and clinical laboratory is described. Design prerequisites that guided hardware selection include: flexibility in experimental control, ease of data handling, system mobility, operational simplicity, and a method of providing clinical feedback. The microcomputer, mass storage, digital input/output, timers, and the auditory and visual modes of interacting with subjects/patients are described. Component costs are illustrated.     

A microprocessor-based psychopathology laboratory: II. Research goals and design prerequisites

The design of a microprocessor-based psychopathology laboratory is influenced by (1) special procedures in many experimental paradigms and (2) some theoretical considerations about psychopathological data. In terms of design prerequisites, these are summarized as flexibility and power to control a spectrum of experiments, large data-processing capacity, ability to provide clinically relevant data on short notice, mobility, and simplicity of operation and programming.     

A microprocessor-based real-time BASIC laboratory: A pulse motor-controlled visual stimulator

Using the Commodore PET as a random pulse generator, an inexpensive visual stimulator for psychophysical experiments can easily be made at low cost. The PIA interface that connects the external experimental devices is easily accessed by PEEKing and POKEing its registers with BASIC. Using pulse motors, two independent stimulator wheels, having 24 different color filters and a 2.4 log (.1 log unit steps) unit range light attenuator, are controlled by a randomized string of pulses via a PIA port, and the responses of the observer as well as the stimulus parameters are automatically written onto the cassette memory for further data analysis.     

A microcomputer-controlled laboratory: Software

The software used in a microcomputer-controlled laboratory is described. Primary emphasis is placed upon describing the capabilities of a powerful, easy-to-use programming language appropriate for controlling research in a wide variety of applications. It is particularly appropriate for physiological and operant laboratories. Design of the language and accompanying operating system follow a rigorous modular, structured approach, with most coding done in high-level languages. As a result, the code is easy to maintain and expand. In addition, it is not difficult to adapt the programs to other microprocessors to take advantage of a rapidly improving technology.     

A microcomputer-based laboratory for psychopathology research in rural settings

An Apple-based computer system for research use in rural mental health settings is described. Hardware and software modifications are detailed. Techniques to aid in the acceptance of psychopathology research programs in these rural settings are discussed.     

Neuropsychology and psychopathology: A progress report

This paper summarizes and discusses the contributions of neuropsychological assessment to various forms of psychopathology. Emphasis is placed upon studies done with the Halstead-Reitan battery and the Wechsler Adult Intelligence Scale, but studies done with other neuropsychological test procedures are also reviewed. The conclusions reached are that neuropsychological tests are sensitive to functional regional brain disorganization in psychopathology, and that they are useful in the diagnostic process for a number of disorders including schizophrenia, psychopathy, mood disorders, and other psychiatric conditions.     

The design,development, and implementation of a microprocessor-based ECG analysis system

This paper describes the research effort to design, develop, and implement a microprocessor-based ECG data acquisition, reduction, and analysis system for operation in real-time. This unit can be attached to three-channel ECG carts and provide an immediate on-site analysis. The basic design and development efforts include (1) the data acquisition, reduction, and matrix assembly, (2) ECG arrhythmia, P-wave, and axis analysis, (3) ECG contour analysis, and (4) a real-time three-channel data acquisition unit. Decision tables are used in the analysis. The implementation of these projects into a small microprocessor-based unit coupled to a three-channel recorder is now in progress. This system, coupled with a small printer, will provide immediate on-site ECG analysis for most cardiovascular dysfunctions.     

Extraversion and psychopathology: A multilevel hierarchical review

We examine relations between extraversion and psychopathology, using a four-level hierarchical structure in which the general domain is divided into two aspects (Communal Extraversion, Agentic Extraversion), four consensual facets (Sociability, Liveliness, Venturesomeness, Dominance), and six NEO facets (Gregariousness, Warmth, Positive Emotions, Activity, Excitement-Seeking, Assertiveness). Our review indicates that extraversion’s negative correlations with depression primarily reflect the aspect of Communal Extraversion, the consensual facet of Liveliness, and NEO Positive Emotions. Its negative associations with social dysfunction largely are due to the aspect of Communal Extraversion, the consensual facet of Sociability, and NEO Warmth, Gregariousness, and Positive Emotions. Finally, externalizing and mania are positively related to the aspect of Agentic Extraversion, the consensual facets of Venturesomeness and Dominance, and NEO Excitement-Seeking.     

Need associations and psychopathology.

The 1960 Picture Identification Test (PIT) provides association scores for 210 need dyads derived from 21 Murray needs. Association scores for 16 clinical-control group pairs were analyzed for differences by t test. The clinical groups represented schizophrenic, neurotic, sex disturbance, and behavior disorder categories. Assertive needs produced the largest number od dyads which discriminated (p less than .05) clinical and control groups. Schizophrenic groups had the largest number of differences from normal controls. Schizophrenics tended to under-associate pairs of Assertive needs, as compared to normals, whereas other groups tended to over-associate these needs. Clinical groups in general over-associated 379 need dyads and under-associated 99 dyads (p less than .05). These results suggest that the frustations of maladjusted people, with regard to need association, are most generally related to insuficient conceptual differentiation of needs.     

Modeling the symptoms of psychopathology: A pluralistic approach

Our understanding of mental disorders has traditionally focused on syndromes and symptom clusters rather than on the nature of the symptom and signs themselves. Using a core symptom of depression, anhedonia, as an extended example, this paper illustrates how the development of multiple models of symptoms, at various scales of analysis, may advance the explanation and classification of mental disorders. We begin by outlining the Phenomena Detection Method (PDM), which links different phases of the inquiry process to provide a methodology for conceptualizing the symptoms of psychopathology and for constructing multi-level models of the pathological processes that comprise them. Next, we apply the PDM to anhedonia, building a compositional explanation of this core symptom by way of multiple models across four scales (levels): molecular, neural, cognitive, and phenomenological. Finally, we evaluate our approach in comparison to existing strategies for understanding mental disorders.     

Thought suppression and psychopathology.

Wegner's seminal investigations of effects of thought suppression on later thought frequency have had a significant impact on recent approaches to understanding emotional disorders characterized by the occurrence of persistent, repetitive, unwanted thoughts. Thought suppression has now been implicated as a etiological and/or maintaining factor in depression, generalized anxiety disorder, specific phobia, posttraumatic stress disorder and obsessive-compulsive disorder. These developments are fairly new, and it has not been until recently that studies have investigated the effects of suppressing thoughts that are actually analogous to problematic thoughts characteristic of emotional disorder. This paper provides a review of this body of work, including the findings and their relevance for existing models of specific disorders. Directions for future research are suggested.