Gene-Environment Interactions in ADHD: The Roles of SES and Chaos

Although attention-deficit/hyperactivity disorder (ADHD) is highly heritable, emerging evidence suggests symptoms are associated with interactions between genes and the environment (GxE) during development. This study tested whether heritability of ADHD symptoms is moderated by two environmental factors: socioeconomic status (SES) and chaos (household disorganisation). A population sample of 520 twin pairs (N = 1040, 52.3% female) from 6 to 15 years completed measures of behavior and home environment. Structural equation modelling was then used to test whether environmental factors were associated with a change in the extent to which genes explain variability in ADHD symptoms. Neither chaos nor SES moderated heritability, with consistent contributions from both genes and environment indicated across socioeconomic strata and levels of chaos. This finding contrasts with those of previous research, underlining the need to replicate results in the emerging field of GxE research across different populations and statistical methods. Robust findings may assist in developing targeted interventions for genetically vulnerable individuals.     

Childhood Maltreatment and its Effect on Parenting among High-Risk Parents

Research evidence indicates that a childhood history of maltreatment affects parental behaviors in adulthood. The aim of the study was to investigate the predictors for parental behaviors among individuals who reported a history of maltreatment. The current study investigated whether attachment styles, emotional regulation and cognitive appraisals of parenting predicted parental behaviors (positive vs. negative). The study also investigated the differential effects of abuse experiences in childhood (physical, sexual, emotional, and neglect) on parental behaviors. The participants were 213 high-risk Jewish and Arab parents of children aged six and under. Participants completed five self-report questionnaires assessing parental behaviors, childhood experiences of abuse and neglect, attachment styles, emotional regulation, and cognitive appraisal of parenthood. The regression analyses revealed that personal attributes such as ethnicity, childhood experience of emotional abuse/neglect, emotional regulation, and appraisal of parenting, predict negative parental behavior. Anxious attachment and childhood emotional abuse and neglect moderated the impact of parenthood appraisal on parenting behaviors. Although physical and sexual abuse had the highest impact on insecure attachment, emotional abuse/neglect had higher predictive power for non-positive parenting. Clinical interventions for improving the capacity for emotional regulation and parent-child relational skills are suggested.     

Trauma Models of the Effects of Childhood Maltreatment

Abstract

Trauma models of child maltreatment effects are addressed, with emphasis on the Diagnostic and Statistical Manual of Mental Disorders' diagnosis of posttraumatic stress disorder and the degree to which it fails to account for many salient symptoms and behaviors associated with maltreatment and victimization in children and adults. Research is presented to support the idea that posttraumatic stress disorder is best conceptualized as a dimensional outcome rather than a categorical all-or-none diagnosis. The PTSD model(s) needs to be either expanded to correct deficiencies or to be integrated into a larger model of the effects of trauma and victimization.     

The Effects of Childhood ADHD Symptoms on Early-onset Substance Use: A Swedish Twin Study

Research has documented that children and adolescents with attention-deficit/hyperactivity disorder (ADHD) are at increased risk of substance use problems. Few studies, however, have focused on early-onset substance use. This study therefore investigated how the two symptom dimensions of ADHD (hyperactivity/impulsivity and inattention) are associated with early-onset substance use, the role of persistent ADHD for the association, and to what extent the association is influenced by genetic and environmental factors. Twins (1,480 pairs) in the Swedish Twin Study of Child and Adolescent Development were followed from childhood to adolescence. ADHD symptoms were measured at age 8–9 and age 13–14 via parent-report, whereas substance use was assessed at age 13–14 via self-report. Results revealed that hyperactive/impulsive symptoms predicted early-onset “sometimes” tobacco use (adjusted odds ratios, 1.12, for one symptom count), controlling for inattentive symptoms and conduct problem behaviors. There is no independent effect of inattentive symptoms on early-onset substance use. Children with persistent hyperactivity/impulsivity (defined as scoring above the 75th percentile at both time points) had a pronounced risk of both early-onset tobacco and alcohol use (adjusted odds ratios from 1.86 to 3.35, compared to the reference group). The associations between hyperactivity/impulsivity and early-onset substance use were primarily influenced by genetic factors. Our results indicated that hyperactivity/impulsivity, but not inattention, is an important early predictor for early-onset substance use, and a shared genetic susceptibility is suggested to explain this association.     

Adverse Effects of Childhood Emotional Maltreatment on Child Behavioral Outcomes

This study used a diverse community sample to test a moderated mediation model, investigating maternal depressive symptoms as a mediator of the relations between maternal emotional maltreatment and child behavior problems; we further tested the moderating effects of observed maternal hostility on these relations. Participants included 64 mother–child dyads (8–11 years old; 59.4% female), in which mothers completed self- and child-report measures and dyads completed a conflict resolution task. Results of a moderated mediation analysis (PROCESS; Hayes, 2013) indicated that the maternal history of emotional maltreatment was associated with increased maternal depressive symptoms, and subsequently with higher child externalizing problems. In addition, these relations were strongest at high levels of observed maternal hostility in the conflict task.     

Childhood Maltreatment and Parental Attitudes Regarding the Use of Corporal Punishment

Journal of Child and Family Studies - Corporal punishment is associated with negative outcomes for children. Increased risk for such adverse parenting practices may be increased for individuals...     

Childhood Maltreatment and PTSD: Spiritual Well-Being and Intimate Partner Violence as Mediators

Childhood maltreatment places individuals, including African American women who are undereducated and economically disadvantaged, at risk for developing posttraumatic stress disorder (PTSD) symptoms. Participants were 192 African American women with a history in the prior year of both a suicide attempt and intimate partner violence (IPV) exposure. They were recruited from a public hospital that provides medical and mental health treatment to mostly low-income patients. A simple mediator model was used to examine if (a) existential well-being (sense of purpose) or religious well-being (relationship with God) mediated the link between childhood maltreatment and adult PTSD symptoms. Sequential multiple mediator models determined if physical and nonphysical IPV enhanced our understanding of the mediational association among the aforementioned variables. Findings suggest that existential well-being mediated the association between childhood maltreatment and adult PTSD symptoms in a simple mediator model, and existential well-being and recent nonphysical IPV served as sequential multiple mediators of this link. However, religious well-being and physical IPV were not significant mediators. Findings underscore the importance of enhancing existential well-being in the treatment of suicidal African American women with a history of childhood maltreatment and IPV.     

Self-Qualities and Self-Leadership as Pathways Linking Childhood Maltreatment to Depression and Relationship Quality

Among adults, childhood maltreatment is widely known to increase depressive symptoms and reduce quality of adult’s intimate relationships. Considering the association between childhood maltreatment and adult depression and relationship quality from systemic theories may help clinicians conceptualize and intervene with their clients. Internal Family Systems is an evidenced based psychotherapy and is a trauma-informed model. Self is one of the core concepts of the Internal Family Systems model and it is theorized to reduce mental health problems such as depression and strengthen adult romantic relationships. Despite this theoretical proposition there is no supporting empirical research. To address this gap, the current study examined Self, specifically the qualities of Self (e.g., compassion) and Self-Leadership (e.g., staying calm in face of distress) as pathways linking childhood maltreatment to depression and relationship quality. Using a sample of adults in a romantic relationship, the current study examined Self-Qualities and Self-Leadership as mediators linking retrospective reports of child maltreatment to current depressive symptoms and relationship quality. Results indicate that the indirect (mediating) effects from childhood maltreatment to depressive symptoms and relationship quality were significant through Self-Qualities, but not Self-Leadership. Findings suggest that childhood maltreatment is associated with less frequent access to the qualities of Self, such as compassion and confidence which, in turn, were associated with fewer depressive symptoms and higher levels of relationship quality. For clinicians, the use of IFS and specifically helping clients increase the Self-Qualities may reduce depressive symptoms and strengthen romantic relationships.

     

The Accuracy of Retrospective Recall of Childhood ADHD: Results from a Longitudinal Study

Attention-deficit/hyperactivity disorder (ADHD) is a childhood-onset condition that may continue into adulthood. When assessing adult patients, clinicians usually rely on retrospective reports of childhood symptoms to evaluate the age-of-onset criterion. Since inaccurate symptom recall may impede the diagnosis and treatment of ADHD, knowledge about the factors influencing retrospective reports is needed. This longitudinal study investigated (a) the accuracy of retrospective symptom ratings by adult participants with a childhood diagnosis of ADHD (self-ratings) and parents or significant others (proxy ratings), and (b) the influence of current ADHD symptom severity and ADHD-associated impairments on retrospective symptom ratings. Participants (N =?55) were members of the Cologne Adaptive Multimodal Treatment (CAMT) study who had been referred and treated for ADHD in childhood and were reassessed in adulthood (average age 27 years). Participants’ retrospective self-ratings were substantially lower than, and did not correlate with, parents’ ADHD symptom ratings provided at study entry, while retrospective symptom ratings provided by proxy respondents correlated moderately with parents’ childhood ratings. In addition, participants were more likely to underreport childhood symptoms (79%) and more frequently denied the presence of three or more childhood symptoms (17%) compared to proxy respondents (65% underreporting, 10% false-negative recall). Proxy respondents’ symptom recall was best predicted by childhood ADHD, while participants’ symptom recall was best predicted by current ADHD symptom severity. ADHD-associated impairments were not correlated with symptom recall after controlling for childhood ADHD. Together, these findings suggest a recall bias in adult patients and question the validity of retrospective reports, even in clinical samples.

     

The Roles of Childhood Maltreatment and Psychopathy in Sexual Recidivism of Treated Sex Offenders

Abstract

The Intensive Treatment Program for Sexual Offenders (ITPSO) at the Correctional Service of Canada (CSC) provides cognitive-behavioral group treatment to federally incarcerated sex offenders. Follow-up data for 81 of these men were examined, looking at psychopathy and childhood maltreatment history as potential predictors of recidivism using Survival Analysis. Offenders who had been placed in foster care as a child were more likely to recidivate; however when PCL-R Factor 2 scores (a history of antisocial behavior) were entered, they predicted over and above foster care history. Childhood physical abuse predicted sexual recidivism; however, childhood sexual abuse and PCL-R scores did not predict sexual recidivism. PCL-R Factor 2 scores predicted violent recidivism.     

The Impact of Protective Factors on Posttraumatic Growth for College Student Survivors of Childhood Maltreatment

Many college students experience traumatic life events in childhood, yet demonstrate personal growth following these experiences. Deriving benefit in the face of adversity has been termed “posttraumatic growth.” The relationship between posttraumatic growth and childhood experiences of abuse and neglect was investigated in a sample of 501 college students. The primary focus was on what protective factors moderated the relationship between childhood experiences of abuse and neglect and later posttraumatic growth. It was found that although the protective factors of acceptance, positive reframing, and emotional support all significantly predicted scores on the Posttraumatic Growth Inventory, only the factor of prosocial adults and the overall number of social and emotional resources experienced moderated the relationship between childhood maltreatment and posttraumatic growth. These findings have implications for designing effective interventions that foster growth in college students who report a history of childhood maltreatment.     

Chased by the Past: The Relation Between Childhood Maltreatment and Fear of Childbirth

Sex Roles - Although childbirth is a normative physiological experience, it may be challenging for some women and especially for those who were exposed to childhood maltreatment. The aim of the...     

Parent Emotion Expression and Autonomic-Linked Emotion Dysregulation in Childhood ADHD

Despite evidence that ADHD is associated with disruptions in emotion regulation, few studies have examined the biological correlates of emotion dysregulation among children with this disorder. Prior work has pointed to roles of the parasympathetic and sympathetic nervous system, as indexed via respiratory sinus arrhythmia (RSA) and cardiac pre-ejection period (PEP), respectively. Work in typically developing populations suggests that parenting behavior and parental emotion expression may shape the development of these systems. To date, a single study has examined the independent and interactive roles of autonomic nervous system functioning and parent emotion expression in youth with ADHD. This study seeks to extend that work. 86 children (42 with ADHD), aged 8–12 years, and a parent completed a parent-child interaction task, while electrocardiography and impedance cardiography data were recorded to derive RSA and PEP. Parent and child emotion word use (positive and negative valence) were coded from recordings of the task. Parents of youth with ADHD used fewer positive emotion words throughout the task. Additionally, throughout the task, children with ADHD engaged in excessive RSA withdrawal from baseline. Further, the association between RSA reactivity and ADHD diagnosis was moderated by parent positive emotion word use. Specifically, those with RSA augmentation and parents displaying high positive affect across the task conditions were least likely to have an ADHD diagnosis. If replicated and extended, these results support the use of interventions specifically designed to increase parental modeling of positive emotions, while simultaneously focusing on building emotion regulation skills in youth with ADHD.     

Parent-Child Interaction Therapy for Puerto Rican Preschool Children with ADHD and Behavior Problems: A Pilot Efficacy Study

This study evaluates the initial efficacy of the Parent-Child Interaction Therapy (PCIT) for Puerto Rican preschool children aged 4–6 years with a diagnosis of attention-deficit/hyperactivity disorder (ADHD), combined or predominantly hyperactive type, and significant behavior problems. Thirty-two families were randomly assigned to PCIT ( n =20) or a 3.5-month waiting-list condition (WL; n =12). Participants from both groups completed pretreatment and posttreatment assessments. Outcome measures included child's ADHD symptoms and behavior problems, parent or family functioning, and parents' satisfaction with treatment. ANCOVAs with pretreatment measures entered as covariates were significant for all posttreatment outcomes, except mother's depression, and in the expected direction ( p <.01). Mothers reported a highly significant reduction in pretreatment hyperactivity and inattention and less aggressive and oppositional-defiant behaviors, conduct problems assessed as problematic, parenting stress associated with their child's behavior, and an increase in the use of adequate parenting practices. For the WL group, there were no clinically significant changes in any measure. Treatment gains obtained after treatment were maintained at a 3.5-month follow-up assessment. PCIT seems to be an efficacious intervention for Puerto Rican families who have young children with significant behavior problems.     

童年中期儿童同伴交往与孤独感的交叉滞后分析

2003年6月和2004年6月追踪调查了430名3、4、5年级儿童,采用交叉滞后分析法探讨了同伴交往与孤独感的相互关系。结果表明:控制了社交自我知觉的影响后,友谊质量与孤独感存在显著的交叉滞后效应;而社会喜好和社会行为在控制了社交自我知觉的作用后,与孤独感不存在显著的相互作用;社交自我知觉与孤独感存在显著的相互预测关系。同伴交往各变量中,社交自我知觉对孤独感具有最大的预测力。     

Significance of Childhood Conduct Problems to Later Development of Conduct Disorder Among Children With ADHD: A Prospective Follow-Up Study

This study investigates whether low to moderate levels of childhood oppositional defiant disorder (ODD) and conduct disorder (CD) behaviors contribute to the development of clinically diagnosed CD in adolescence, in children with attention deficit hyperactivity disorder (ADHD). Participants were 207 White boys (ages 6-12) with ADHD free of conduct disorder diagnoses. Parent and teacher ratings were obtained. Participants were assessed at mean age 18 by clinicians blind to childhood status. A non-ADHD group (recruited in adolescence) was also studied. ODD behavior ratings did not predict CD in adolescence, whereas CD behavior ratings did. No single ODD or CD behavior predicted adolescent outcome. ADHD probands with very low ratings (Not at all, Just a little) by parents and teachers on all CD behaviors were still at significantly increased risk for CD in adolescence, compared to non-ADHD controls. The same relationships were found between childhood ODD and CD behaviors, and antisocial personality disorder in adulthood (mean age, 25). We conclude that childhood ADHD is a developmental precursor of later antisocial disorder, even in the absence of comorbid ODD or CD in childhood. However, low levels of CD-type problems are not innocuous, because they predict later CD among children with ADHD without comorbid CD.     

Women with Childhood ADHD: Comparisons by Diagnostic Group and Gender

This study compared adult women with childhood ADHD to adult women without childhood ADHD and to adult men with childhood ADHD. The participants, all from a larger longitudinal study, included 30 women and 30 men (approximately age 23 to 24) with childhood ADHD, and 27 women without ADHD. Women with childhood ADHD were matched to comparison women on age, ethnicity, and parental education, and to men with childhood ADHD on age, ethnicity, and IQ. Self- and parent-reports of internalizing, interpersonal, academic, and job impairment, as well as substance use and delinquency indicated group differences on measures of self-esteem, interpersonal and vocational functioning, as well as substance use. Follow-up planned comparison tests revealed that almost all of these differences emerged by diagnostic status, and not by gender. This study adds to research on the negative adult outcomes of ADHD and demonstrates that the outcomes of men and women with childhood ADHD are relatively similar.     

Childhood Emotional Maltreatment as a Robust Predictor of Suicidal Ideation: A 3-Year Multi-Wave,Prospective Investigation

Despite literature suggesting a relationship between child maltreatment and suicidal ideation, few studies have examined the prospective course of this relationship. The current study examined this relationship in a sample of 682 community youth who were followed over the course of 3 years. Repeated measures of suicidal ideation, emotional maltreatment, and depressive symptom severity were examined in multi-wave path analysis models. Overall, results suggest that emotional maltreatment over time contributes uniquely to the prospective prediction of suicidal ideation, even when controlling for age, previous suicidal ideation, biological sex, and depression symptom severity. Unlike previous studies that have only measured emotional maltreatment at one-time point, the current study demonstrates that emotional maltreatment contributes unique risk to suicidal ideation prospectively among youth. Results speak to the importance of examining emotional maltreatment and suicidal ideation within prospective models of risk and suggest that emotional maltreatment is a robust predictor of suicidal ideation, over and above history of suicidal ideation and depression.     

Childhood ADHD and Executive Functioning: Unique Predictions of Early Adolescent Depression

Research on Child and Adolescent Psychopathology - Given the increasing prevalence of adolescent depression, identification of its early predictors and elucidation of the mechanisms underlying its...