Psychosocial correlates of bulimic symptomatology among male athletes

ObjectivesTo examine the relationship of four psychosocial constructs – body dissatisfaction, restrained eating, drive for muscularity, and negative affect – that have been identified as potential risk factors for bulimic symptoms in male athletes.DesignWe used a cross-sectional design and self-report questionnaires.MethodsParticipants were 203 male, NCAA Division I athletes who were drawn from three different U.S. universities and who competed in 17 different varsity sports. Athletes completed self-report measures of body satisfaction, dietary restraint, drive for muscularity (i.e., muscularity behaviors, muscular body image), negative affect (i.e., fear, hostility, guilt, sadness), and bulimic symptomatology.ResultsAfter controlling for the effects of body mass and social desirability, hierarchical regression analysis showed that the psychosocial variables explained an additional 21% of the variance in bulimic symptoms. In the full model, engaging in muscle building behaviors (β = .16), such as lifting weights, as well as restricting caloric intake (β = .33) were associated with higher levels of bulimic symptomatology; negative affect and body dissatisfaction were not.ConclusionsMale athletes' bulimic symptomatology is best explained by the extent to which they report engaging in behaviors to become leaner (i.e., less body fat) and more muscular.     

Concurrent and predictive electrodermal correlates of symptomatology in recent-onset schizophrenic patients.

Electrodermal activity and symptomatology were interrelated in a group of 56 male and 13 female recent-onset schizophrenic patients. Electrodermal activity was indexed by the frequency of nonspecific skin conductances responses and the number of trials to habituation of the skin conductance orienting response. Symptomatology was assessed by the Brief Psychiatric Rating Scale (BPRS) on two separate test occasions. The first test occasion was during the inpatient period when psychotic symptoms were prevalent and medications were variable. The second test occasion was several months later during an outpatient period when symptoms were stabilized and medications held constant. Electrodermal activity was positively and significantly related to a number of symptoms in male patients, most reliably the BPRS factors Activation and Hostility/Suspiciousness. These relationships were most consistent during the outpatient period. Of particular theoretical interest, greater electrodermal activity during the inpatient period was associated with greater outpatient psychopathology. The results suggest that heightened inpatient electrodermal activity is predictive of poor short-term symptomatic recovery in recent-onset, acute, male schizophrenic patients.     

Occult white matter damage contributes to intellectual disability in tuberous sclerosis complex

Whether patients with tuberous sclerosis complex (TSC) have brain normal-appearing white matter (NAWM) damage and whether such damage contributes to their intellectual disability were examined in 15 TSC patients and 15 gender- and age-matched healthy controls using diffusion tensor imaging (DTI). Histogram and region of interest (ROI) analyses of the mean diffusivity (MD) and fractional anisotropy (FA) were performed in the NAWM. Correlations between diffusion indices and the full-scale intelligence quotient (FSIQ) and normalized lesion volume were also investigated. Compared with controls, both histogram and ROI analyses showed significant (P < .05) increased MD and decreased FA in the NAWM of TSC patients. In TSC patients, some of the histogram- and ROI-derived diffusion indices of the NAWM were correlated with FSIQ (P < .01), but none of them were correlated with the normalized lesion volume. These findings indicate that TSC patients have occult damage in the NAWM, which might be an important neural basis for intellectual disability in these patients.     

Neurofunctional correlates of personality traits in relapsing-remitting multiple sclerosis: An fMRI study

Extraversion and Neuroticism are two fundamental dimensions of human personality that influence cognitive functioning in healthy subjects. Little is known about personality changes that may occur in patients with multiple sclerosis (MS) nor about, in particular, their neurofunctional basis. The aim of this study is to determine the impact of personality characteristics on brain activity in patients with MS. Eighteen patients with clinically definite relapsing-remitting MS without any evidence of psychiatric or cognitive disorders and thirteen healthy controls matched for age, gender and education were investigated using functional magnetic resonance imaging (fMRI) during the execution of an “n-back” task. No differences were detected on the behavioral tests between the two groups, although the MS patients had lower total IQ and showed a trend towards higher Extraversion and Neuroticism scores than did the controls. fMRI analyses demonstrated that Extraversion scores were positively associated with brain activity in the fronto-parietal network including the superior parietal lobule and dorsolateral prefrontal cortex in both groups during the high load condition of the n-back task. Given the overlapping neural systems found in the two groups, we suggest that the neural activity associated with specific personality dimension is a neurophysiological characteristic preserved in patients with MS at an early stage in the course of their disease.     

Neurofunctional correlates of personality traits in relapsing-remitting multiple sclerosis: An fMRI study

Extraversion and Neuroticism are two fundamental dimensions of human personality that influence cognitive functioning in healthy subjects. Little is known about personality changes that may occur in patients with multiple sclerosis (MS) nor about, in particular, their neurofunctional basis. The aim of this study is to determine the impact of personality characteristics on brain activity in patients with MS. Eighteen patients with clinically definite relapsing-remitting MS without any evidence of psychiatric or cognitive disorders and thirteen healthy controls matched for age, gender and education were investigated using functional magnetic resonance imaging (fMRI) during the execution of an “n-back” task. No differences were detected on the behavioral tests between the two groups, although the MS patients had lower total IQ and showed a trend towards higher Extraversion and Neuroticism scores than did the controls. fMRI analyses demonstrated that Extraversion scores were positively associated with brain activity in the fronto-parietal network including the superior parietal lobule and dorsolateral prefrontal cortex in both groups during the high load condition of the n-back task. Given the overlapping neural systems found in the two groups, we suggest that the neural activity associated with specific personality dimension is a neurophysiological characteristic preserved in patients with MS at an early stage in the course of their disease.     

Auditory overselectivity in autistic children

Autistic and normal children were trained to respond to a complex stimulus containing two auditory components. After the discrimination was acquired, the individual components were presented separately, allowing assessment of the extent to which the child's responding was controlled by one or both of the cues. The autistic children, unlike the normal children, provided evidence for stimulus overselectivity in that 6 of 8 autistic subjects responded to only one of the components. These results are consistent with those of previous studies which showed that when autistic children are presented with a complex visual or multiple-modality stimulus, they selectively respond to only one component of the complex. The present results extend the stimulus overselectivity hypothesis to the situation where all of the stimuli occur within the auditory modality. It is suggested that auditory overselectivity may partially account for autistic deficits in speech comprehension.     

The autistic moment in psychotherapy

This is a report on the author's experience in treating four autistic children and their families. The importance of making available the therapist's own autism is stressed. The difficulty in doing this and reverting defensively to an administrative approach is described. A previous paper discussed the corrective autistic experience with a focus on the autistic person. This follow-up describes the autistic moment which is a relational experience between the therapist and both the autistic person and the autistic family. The family needs to have an experience of its own autism as a continuum of normal before it can relate to an autistic child. To the extent that the therapist can bring his own autism into the therapy can the family experience its own. The patients are the person, the relationships, the family, and the therapist.The author would like to thank Richard B. Anderson, MD, Lindy T. Barnett, MSW, David V. Keith, MD, JoEllen Barnett Smith, MA, and Orion Smith for their participation as cotherapists. The comments made on an earlier draft of this paper by the members of the Atlantic Psychiatric Clinic are warmly acknowledged. Valuable editorial assistance has been extended by Robert Garfield, MD, and Stuart Sugarman, MD. Lastly, the author would like to extend his appreciation to Robert R. Haubrich, PhD, for stimulating his interest in the field of comparative ethology.Presented at the Conference Honoring the Retirement of Carl A. Whitaker, MD, in Madison, Wisconsin, June 25, 1982.     

Memory in autistic spectrum disorder

Behavioral evidence concerning memory in forms of high-functioning autism (HFA) and in moderately low-functioning autism (M-LFA) is reviewed and compared. Findings on M-LFA are sparse. However, it is provisionally concluded that memory profiles in HFA and M-LFA (relative to ability-matched controls) are similar but that declarative memory impairments are more extensive in M-LFA than in HFA. Specifically, both groups have diminished memory for emotion- or person-related stimuli. Regarding memory for nonsocial stimuli, both groups probably have mental-age-appropriate nondeclarative memory, and within declarative memory, both groups have mental-age-appropriate immediate free recall of within-span or supraspan lists of unrelated items, as well as cued recall and paired associate learning. By contrast, recognition is largely unimpaired in HFA but moderately impaired in M-LFA, and free recall of meaningful or structured stimuli is moderately impaired in HFA but more severely impaired in M-LFA. Theoretical explanations of data on declarative memory in HFA identify problems in the integrative processing, or the consolidation and storage, of complex stimuli or a specific problem of recollection. Proposed neural substrates include the following: disconnectivity of primary sensory and association areas; dysfunctions of medial prefrontal cortex, hippocampus, or posterior parietal lobe; or combinations of these associated with neural disconnectivity. Hypothetically, perirhinal dysfunction might explain the more extensive declarative memory impairments in M-LFA. Foreseeable consequences of uneven memory abilities in HFA and M-LFA are outlined, including possible effects on language and learning in M-LFA. Finally, priorities for future research are identified, highlighting the urgent need for research on memory in lower functioning individuals.     

Stability of anxious symptomatology in children

The stability of anxiety states and symptoms was assessed in a sample of 150 anxious and nonanxious children. A number of assessment methods including a semistructured interview, self-report instruments, psychophysiological measures, and parental reports were used initially and at intervals up to 6 months later. The majority of children with a diagnosed anxiety disorder at the initial assessment still manifested significant symptomatology at the 6 month follow-up. However, stability of specific anxiety symptoms when assessed by self- and parental reports was mixed. With respect to psychophysiological assessment, stability of responses was evident at 2 weeks but not after 6 months. Results are discussed in terms of the stability of diagnoses and symptomatology, and the need for thematically relevant self-reports and behavioral assessment tasks. Recommendations are made for the development of a reliable, multimethod strategy to assess the multiple domains of childhood anxiety.This study was supported in part by NIMH Grant MH43252.     

Typical hierarchical processing in autistic adults

ABSTRACT

Previous research suggests that autistic individuals exhibit atypical hierarchical processing, however, most of these studies focused solely on children. Thus, the main aim of the current study was to investigate the presence of atypical local or global processing in autistic adults using a traditional divided attention task with Navon’s hierarchical figures. Reaction time data of 27 autistic and 25 neurotypical (NT) adults was analysed using multilevel modelling and Bayesian analysis. The results revealed that autistic, like NT, adults experienced a global precedence effect. Moreover, both autistic and NT participants experienced global and local interference effects. In contrast to previous findings with children, the current study suggests that autistic adults exhibit a typical, albeit unexpected, processing of hierarchical figures.     

Reducing stimulus overselectivity in autistic children

It has been repeatedly reported that when presented with a discrimination task involving multiple cues, autistic children, as compared to normal children, tend to respond on the basis of only a restricted portion of the component cues. This phenomenon has been called stimulus overselectivity and has been implicated as a possible basis for some of the pronounced behavioral deficits characteristic of autism. Examination of the results of several previous studies suggests that the overselectivity effect might be reduced with repeated exposure to testing. However, since the previous studies were not designed to test this hypothesis, no conclusions were drawn regarding variables influencing the reduction of the overselectivity phenomenon. The present investigation was therefore conducted to determine if stimulus overselectivity in autistic children is changed as a function of repeated exposure to testing. Nineteen autistic children were trained on a discrimination task with a cue complex composed of two visual cues. After the children reached criterion on the task, they were exposed to a testing phase with probe trials where the cue components were presented singly. The results indicated that 16 of the children initially showed overselectivity and 3 responded to both cues. Of the 16 children who showed overselectivity, 13 decreased their level of overselectivity with continued testing. These results are discussed in relation to variables in the testing procedure itself and to the literature on selective attention.This research was funded by USPHS Research Grants MH11440, MH28210, and MH28231 from the National Institute of Mental Health. The authors wish to acknowledge the assistance of Cathy Hook, Hannelore Wilhelm, and Jon Killion in conducting this research.     

Functional neuroimaging of autistic disorders

Functional neuroimaging methods hold promise for elucidating the neurobiology of autistic disorders, yet they present difficult practical and scientific challenges when applied to these complex and heterogeneous syndromes. Single-state studies of brain metabolism and blood flow thus far have failed to yield consistent findings, but suggest considerable variability in regional patterns of cerebral synaptic activity. Patients with idiopathic autism are less likely to show abnormalities than are patients with comorbid illness or epilepsy. Activation studies have begun to suggest alterations in brain organization for language and cognition. Neurotransmitter studies using positron emission tomography (PET) suggest abnormalities of serotonergic and dopaminergic function. Studies using magnetic resonance spectroscopy (MRS) have begun to document metabolic deficits in the frontal cortex and cerebellum. A single study using magnetoencephalography suggests a high incidence of epileptiform activity in children with autistic regression. Research needs include well-controlled developmental studies, particularly of young subjects and relatively homogeneous subgroups, which balance scientific rigor with ethical constraints. Investigations of the serotonergic and dopaminergic systems, limbic-based memory and emotional systems, and the role of epileptiform activity in autism represent priorities for future research.     

Favourite objects of autistic children

Favourite objects (FOs) of autistic children were compared with the FOs of healthy preschool and school children as well as mentally handicapped children. Three clusters of objects were obtained for normal children (comprising primary transitional objects and their forerunners, secondary transitional objects, and non-cuddly toys). When autistic children and mentally handicapped children were included, a fourth cluster of deviant objects was found. Frequency distributions of the two handicapped groups in the clusters were similar. Similarities between the two handicapped groups were also found within each cluster. The occurrence of secondary transitional objects was rare in the handicapped groups. The characteristics of "autistic" FOs reported in earlier case studies (e.g. being hard, often having an exciting effect, not being used in their adequate functions) were typical only of objects in the fourth cluster.     

Posttraumatic symptomatology in children exposed to war

This study examines affective and behavioral symptomatology in two groups of school-age children who were traumatized to different degrees during the war in Croatia (N = 1034). Six self-reported questionnaires were used to assess the following: number and type of war experiences, PTSD symptoms, anxiety, depression, psychosomatic symptoms, and psychosocial adaptation. Canonical discriminant analysis yielded a significant discriminant function that indicates moderate differentiation between the two groups of children according to the assessed symptoms. The results of a 2 x 2 x 2 ANOVAs (gender x age x level of traumatization) indicate that the children's reactions to war traumata varied in respect to all factors, as well as their interaction. The results indicate that gender differences are more prominent in older children. Older girls report more posttraumatic stress reactions, anxiety and depression, but at the same time seem better adapted than boys. Younger children, particularly those who survived more war even report more PTSD symptoms than older children.     

Unrepressed unconscious and unsaid in addictive symptomatology

The aim of this work is to understand, from a developmental-relational perspective, the emotional nature of addictive symptoms. Many studies have shown that addictions are linked to traumatic emotions that, once activated, could cause a feeling of emotional confusion that in the most severe cases could be connected to the fear that the Self might disintegrate. Before understanding the relationship between dissociation and addictions, it is essential to distinguish disintegration (désagrégation, in the language of Pierre Janet) and dissociation. Indeed, if the disintegration is a structural and pathological condition of the personality caused by early and chronic emotional traumatic memories, the dissociation is a defensive reaction to a stress: this reaction can be normal (flexible and adequate) or pathological (rigid and inadequate). Thus, addictive behaviours could be associated to a dissociative reaction in individuals with a structural dissociation of the personality (désagrégation). This disintegration would be linked to traumatic emotions: unconscious and unsymbolised emotions. On the unconscious nature of these emotions, the author of this paper underlines the role of the unrepressed unconscious, which in addicts would seem to be impaired.