Cognitive Vulnerabilities as Predictors of Stress Generation in Early Adolescence: Pathway to Depressive Symptoms

Although individuals with depression have been found to experience a higher rate of stress in their lives, it remains unclear to what extent other personal characteristics may contribute to stress generation. The current study extended past research by examining the effects of two theoretically and empirically supported cognitive vulnerabilities to depression (negative cognitive style and rumination) as predictors of dependent interpersonal and achievement events, independent events, and relational peer victimization. In a diverse sample of 301 early adolescents (56 % female; M_age?=?12.82 years), we found that negative cognitive style prospectively predicted the experience of dependent interpersonal stress and relational victimization, and that rumination did not predict stress in any of the domains. Furthermore, the occurrence of intervening stress mediated the associations between negative cognitive style and subsequent depressive symptoms. Additionally, whereas negative cognitive style predicted relational victimization among both boys and girls, girls were particularly vulnerable to developing depressive symptoms following the occurrence of relational victimization. Thus, a negative cognitive style may contribute to the occurrence of stressful events, which in turn increases depressive symptoms. Girls may be particularly reactive to relational victimization, representing one pathway through which sex differences in depression may emerge.     

The mediation component of the hopelessness depression in relation to negative life events

A necessary test of the mediational processes component of the hopelessness theory of depression is to test whether the individuals who have negative attributional style and experience negative life events are likely to make negative attributions for the negative events they confront. The present study, using undergraduate students, find that the negative attributional style do not predict negative attributions subjects made for the negative life events they experience within a period of 3 months. However, subjects' negative attributions for the negative life events coupled with the experience of a high number of negative life events predicted their depressive symptomatology. The depressive symptomatology is found not to be mediated through hopelessness. The findings are discussed in relation to the hopelessness theory of depression.     

The Hopelessness Theory of Depression: A Test of the Diathesis–Stress and Causal Mediation Components in Third and Seventh Grade Children

The goal of the current study was to test the diathesis–stress and causal mediation components of the hopelessness theory of depression in third- and seventh-grade children. The procedure involved an initial assessment of depressive symptoms, hopelessness, and the 3 cognitive styles posited as vulnerability factors by hopelessness theory. The procedure also involved a series of 6 weekly follow-up assessments in which depressive symptoms, hopelessness, and the occurrence of negative events were assessed. A depressogenic attributional style interacted with negative events to predict increases in depressive symptoms in seventh-grade children but not in third-grade children. A depressogenic inferential style about consequences interacted with negative events to predict increases in depressive symptoms in both third- and seventh-grade children. Last, a depressogenic inferential style about the self interacted with negative events to predict increases in depressive symptoms in third- and seventh-grade girls but not boys. None of these interactions were mediated by hopelessness.     

无望与希望：从认知方式看无望抑郁的风险和恢复

由于视角和侧重点的差异, 无望抑郁认知研究基本上可以分为两大取向。一是以认知易感-压力模型为核心, 围绕“无望”展开的病因学研究, 关注认知危险因素、消极生活事件与无望以及抑郁风险之间的关系。二是以恢复模型为核心, 围绕重获“希望”展开的无望抑郁恢复研究, 关注认知保护因素、积极生活事件与重获希望以及抑郁缓解之间的关系。厘清一些相关问题、整合两个研究取向有利于准确评估个体无望抑郁的风险和弹性恢复。     

Emotion Beliefs,Emotion Regulation,and Emotional Experiences in Daily Life

One potential factor that could influence how individuals with at least moderate symptoms of depression cope with upsetting events in their daily lives is the beliefs that these individuals hold about whether emotions are malleable or fixed. The current study adopted an experience sampling approach to examine how the beliefs about emotion’s malleability related to daily positive and negative affect and daily emotion regulation efforts among individuals with at least moderate symptoms of depression (N = 84). Results demonstrated that individuals having at least moderate symptoms of depression who held more malleable beliefs about emotions reported decreased negative affect both overall during the day and specifically in response to daily upsetting events. Additionally, these individuals who held more malleable beliefs about their emotions also reported more daily use of cognitive reappraisal to regulate their emotions in response to upsetting daily events. Results from the current study extend previous work examining the relationship between emotion malleability beliefs, emotional experiences, and emotion regulation to examine these relationships in people who are moderately depressed as they navigate the emotional landscape of their daily lives.     

A test of the hopelessness theory of depression in youth psychiatric inpatients

Evaluated the hopelessness theory of depression among youth psychiatric inpatients. According to the hopelessness theory of depression, negative attributional style may cross-sectionally relate to an array of psychopathological symptoms. However, in the presence but not the absence of negative life events, negative attributional style relates to the onset and exacerbation of depressive (not other) symptoms. Moreover, negative attributional style relates to depression onset or exacerbation specifically via changes in hopelessness (not other mediators). This study of 60 youth psychiatric inpatients (22 boys and 38 girls; ages 9 to 17, M = 14.33, SD = 1.86), 34 of whom were assessed 2 months after leaving the hospital, tested hopelessness theory. At baseline, participants completed self-report questionnaires on attributional style, hopelessness, self-esteem, depression, and anxiety; at follow-up, questionnaires on negative life events and symptoms were completed. Chart diagnoses were available. Results were consistent with all hypotheses derived from hopelessness theory.     

Cognitive content-specificity in future expectancies: role of hopelessness and intolerance of uncertainty in depression and GAD symptoms

The present study examined cognitive content-specificity in future-event predictions associated with symptoms of depression and generalized anxiety disorder (GAD). College undergraduates (N=284) completed measures of depression, GAD, and rated their certainty that a given set of positive and negative outcomes were or were not likely to happen in their future. Participants also completed measures of hopelessness and intolerance of uncertainty (IU). Individuals (N=263) completed the same measures again 6 weeks later. Certainty in an absence of positive future outcomes was associated with symptoms of depression but not GAD, and hopelessness mediated this relationship - concurrently and when examining change scores over 6 weeks. Certainty in negative outcomes was concurrently associated with both symptoms of depression and GAD, and hopelessness partially mediated these relationships. IU predicted concurrent increases in depression and GAD symptoms, and negative-outcome certainty partially mediated the IU-depression but not the IU-GAD symptom relationship. Change in certainty did not mediate the relationship between changes in IU and GAD symptoms but partially mediated the relationship between change in IU and depression symptoms over time. Hopelessness appears to play a unique role in the relationship between reduced anticipation of positive future outcomes and depression. Although less clearly suggested by the data, IU may contribute to both depression and GAD symptoms but may do so through different pathways.     

Attributional style and depressive symptoms in adolescents: an examination of the role of various indicators of cognitive vulnerability

This study focuses on the hopelessness theory to explain depressive symptoms in adolescents. The aim is to assess which dimensions of the attributional style (causal attribution, attribution of consequences, implications for the self, total score, and weakest link score) better moderate the impact of negative events on the increase of depressive symptoms. For this purpose, 856 Spanish adolescents (449 girls and 407 boys, ages between 14 and 17 years) were assessed at the beginning of the school year and at follow-up 6 months later. They completed measures of depressogenic cognitive style [Hankin, B. L., & Abramson, L. Y. (2002). Measuring cognitive vulnerability to depression in adolescents: Reliability, validity, and gender differences. Journal of Clinical Child and Adolescent Psychology, 31, 491-504], negative life events, and depressive symptoms. The results show that only the dimension of attribution of stable and global causes moderated the impact of the negative events on the increase of depression at follow-up. The results are discussed in terms of the meaning of the weakest link score and the construct of attributional style from a developmental perspective.     

Adult attachment dimensions and specificity of emotional distress symptoms: prospective investigations of cognitive risk and interpersonal stress generation as mediating mechanisms

Three prospective studies examined the relation between adult attachment dimensions and symptoms of emotional distress (anxiety and depression). Across all three studies, avoidant and anxious attachment prospectively predicted depressive symptoms, and anxious attachment was associated concurrently with anxiety symptoms. Study 2 tested a cognitive risk factors mediational model, and Study 3 tested an interpersonal stress generation mediational model. Both cognitive and interpersonal mediating processes were supported. The cognitive risk factors pathway, including elevated dysfunctional attitudes and low self-esteem, specifically mediated the relation between insecure attachment and prospective elevations in depression but not anxiety. For the interpersonal stress generation model, experiencing additional interpersonal, but not achievement, stressors over time mediated the association between insecure attachment and prospective elevations in depressive and anxious symptoms. Results advance theory and empirical knowledge about why these interpersonal and cognitive mechanisms explain how insecurely attached people become depressed and anxious.     

Neuroticism,Life Events and Negative Thoughts in the Development of Depression in Adolescent Girls

Theories of depression suggest that cognitive and environmental factors may explain the relationship between personality and depression. This study tested such a model in early adolescence, incorporating neuroticism, stress-generation and negative automatic thoughts in the development of depressive symptoms. Participants (896 girls, mean age 12.3 years) completed measures of personality and depressive symptoms, and 12 months later completed measures of depressive symptoms, recent stressors and negative automatic thoughts. Path analysis supported a model in which neuroticism serves as a distal vulnerability for depression, conferring a risk of experiencing dependent negative events and negative automatic thoughts, which fully mediate the effect of neuroticism on later depression. A second path supported a maintenance model for depression in adolescence, with initial levels of depression predicting dependent negative events, negative automatic thoughts and subsequent depressive symptoms. Unexpectedly, initial depression was also associated with later independent life events. This study establishes potential mechanisms through which personality contributes to the development of depression in adolescent girls.     

Negative attributional style, hopelessness depression and endogenous depression

The hopelessness theory of depression [Abramson, L. Y., Metalsky, G. I. & Alloy, L. B. (1989). Hopelessness depression: a theory-based subtype of depression. Psychological Review, 96, 358-372.] postulates that a negative attributional style represents a risk factor for a particular constellation of depressive symptoms, termed 'hopelessness depression'. Four studies tested the relation of negative attributional style to hopelessness depression symptoms versus endogenous depression symptoms. Despite the considerable overlap of hopelessness and endogenous depression symptoms, negative attributional style was more related to the former than the latter, consistent with hopelessness theory.     

Cognitive vulnerability to depression, rumination, hopelessness, and suicidal ideation: multiple pathways to self-injurious thinking

In order to advance the detection and prevention of suicide, recent research has focused on predictors of suicidal ideation and behavior such as negative cognitive styles, dysfunctional attitudes, hopelessness, and rumination. In this study the relationships among these risk factors in the context of the Attention Mediated Hopelessness (AMH) theory of depression are examined. One hundred and twenty-seven undergraduates in the Cognitive Vulnerability to Depression (CVD) project were followed for 2.5 years. The CVD project followed initially nondepressed freshmen, at either high or low cognitive risk for depression, in order to predict onsets and recurrences of depressive disorders. The presence and duration of suicidal ideation were predicted prospectively by rumination and hopelessness, and hopelessness partially mediated the relationship between rumination and ideation and fully mediated the association between rumination and duration of suicidality. Further, rumination mediated the relationship between cognitive vulnerability and suicidal ideation.     

Perceived Everyday Discrimination and Depressive Symptoms: Does Cognitive Style Mediate?

In the hopelessness theory of depression, a causal chain from stressors (e.g., perceived everyday discrimination [PED]) to 5 negative cognitive styles (NCSs) and depressive symptoms is delineated. In a sample of 243 diverse community college students, PED was positively associated with 4 NCSs. Furthermore, 2 specific NCSs were associated with depressive symptoms and mediated the effect between PED and depressive symptoms. Implications for research and practice with individuals who experience PED are discussed.     

Cognitive vulnerability and frontal brain asymmetry: common predictors of first prospective depressive episode

The hopelessness theory of depression proposes that individuals with a depressogenic cognitive style are more likely to become hopeless and experience depression following negative life events. Although the neurophysiological underpinnings of cognitive style remain speculative, research indicates that decreased relative left frontal brain electrical activity holds promise as a traitlike marker of depression. This begs the question: Do measures of depressogenic cognitive style and resting frontal brain asymmetry index a common vulnerability? The present study provides preliminary support for this hypothesis. At baseline assessment, increased cognitive vulnerability to depression was associated with decreased relative left frontal brain activity at rest in individuals with no prior history of, or current, depression. Following baseline assessment, participants were followed prospectively an average of 3 years with structured diagnostic interviews at 4-month intervals. Both cognitive vulnerability and asymmetric frontal cortical activity prospectively predicted onset of first depressive episode in separate univariate analyses. Furthermore, multivariate analyses indicated that cognitive vulnerability and frontal asymmetry represented shared, rather than independent, predictors of first depression onset.     

The response styles theory of depression: A test of specificity and causal mediation

This prospective study tested the diathesis-stress and causal mediation components of the response styles theory of depression. In addition, it examined whether rumination predicts increases in anxious as well as depressive symptoms. At Time 1, 87 college students completed measures of rumination, hopelessness, depressive symptoms, and anxious symptoms. Participants also completed measures of hopelessness, depressive symptoms, and anxious symptoms at three time points later in the semester: immediately after receiving their most difficult midterm exam grade (Time 2), 4–8 hours later (Time 3), and 4 days later (Time 4). Regardless of exam outcome, the tendency to ruminate in response to depressed mood was associated with: (1) increases in anxious symptoms between Time 1 and Time 3; and (2) increases in both anxious and depressive symptoms between Time 1 and Time 4. In addition, the relationship between rumination and increases in both depressive and anxious symptoms was mediated by hopelessness. In other words, individuals with a ruminative response style exhibited increases in both depressive and anxious symptoms because they exhibited increases in hopelessness.     

Positive attributional style,life events and their effect on children's mood: Prospective study

The present study extended previous research into the role of cognitive style in predicting depressive symptoms in children by examining positive attributional style for positive events in a prospective manner, with a focus on the influence of prior life experience. A non‐clinical sample of 102 children (aged 10–12 years) was recruited. Participants completed self‐report measures of depression, attributional style, stressful life events, and positive life events on two occasions (approximately 6 months apart). Positive attributional style for positive events moderated the relationship between negative life events and follow‐up depressive symptoms. Number of positive events did not significantly moderate the negative life events–depression symptoms relationship although there was a trend in the expected direction. Positive attributional style for positive events appeared to act as both a mediator and moderator in the positive events–depression symptoms relationship. Theoretical and clinical implications of these findings are discussed.     

Cognitive reactivity mediates the relationship between neuroticism and depression

Although neuroticism has long been established as an important risk factor for depression, the mechanisms through which this temperamental predisposition translates into the occurrence of symptoms are still relatively unclear. This study investigated cognitive reactivity, i.e. the ease with which particular patterns of negative thinking are reactivated in response to mild low mood, as a potential mediator. Individuals with (N = 98) and without a previous history of depression (N = 83) who had provided neuroticism scores six years previously were assessed for cognitive reactivity and current symptoms of depression using self-report questionnaires. Tendencies to respond to mild low mood with ruminative thinking mediated the relation between neuroticism and current symptoms of depression in both groups. Reactivation of hopelessness and suicidal thinking occurred as an additional mediator only in those with a history of previous depression. The results suggest that neuroticism predisposes individuals to depression by generally increasing the likelihood of ruminative responses to low mood. In those with a history of depression in the past, neuroticism additionally increases risk of recurrence by facilitating reactivation of previously associated patterns such as suicidal thinking and hopelessness. These findings suggest potential targets for interventions to help preventing the occurrence, or recurrence of depression in those who due to their temperamental predisposition are at an increased risk.     

Reducing hopelessness: the interation of enhancing and depressogenic attributional styles for positive and negative life events among youth psychiatric inpatients

A recovery model of depression (Needles & Abramson, 1990 Journal of Abnormal Psychology, 99, 156-165) proposes that depressed individuals who exhibit an enhancing attributional style for positive events (i.e. make stable, global attributions) will be more likely to regain hopefulness and, thereby, recover from depression when positive events occur. While only a few studies have directly tested this model among clinical and nonclinical adult samples, none have tested a clinical sample of children and adolescents. Furthermore, prior studies testing this model have failed to examine the interactive role of an 'enhancing attributional style' for positive events with a 'depressogenic attributional style' for negative events, as prescribed by the hopelessness theory of depression (Abramson, Metalsky, & Alloy, 1989 Psychological Review, 96, 358-372). The current study presents data demonstrating that depressogenic and enhancing attributional styles interact to predict differential decreases in hopelessness. Implications of these findings and suggestions for future research also are presented.     

Positive life events, attributional style, and hopefulness: testing a model of recovery from depression

A model of a recovery process from depression that is compatible with the hopelessness theory of depressive onset is proposed. This model predicts that depressives who have an enhancing attributional style for positive events (i.e., make global, stable attributions for such events) will be more likely to regain hopefulness and, thereby, recover from depression, when positive events occur. This prediction was tested by following a group of depressed college students longitudinally for 6 weeks. Although neither positive events alone nor attributional style alone predicted reduction in hopelessness, depressives who both showed the enhancing attributional style for positive events and experienced more positive events showed dramatic reductions in hopelessness which were accompanied by remission of depressive symptoms. Thus, attributional style for positive events may be a factor that enables some depressives to recover when positive events occur in their lives.     

Negative cognitive styles, dysfunctional attitudes, and the remitted depression paradigm: a search for the elusive cognitive vulnerability to depression factor among remitted depressives

Results from studies using a behavioral high-risk design and approximations to it generally have corroborated the cognitive vulnerability hypothesis of depression, whereas results from remitted depression studies typically have not. Suspecting that design features of previously conducted remitted designs likely precluded them from detecting maladaptive cognitive patterns, the authors conducted a study featuring the remitted design that has been successful in studies of a biological vulnerability for depression. Participants' current depressive symptoms, negative cognitive styles (hopelessness theory), dysfunctional attitudes (Beck's theory), and lifetime prevalence of clinically significant depression were assessed. Participants who had remitted from an episode of clinically significant depression had more negative cognitive styles, but not greater levels of dysfunctional attitudes, than did never depressed individuals.