Retrospective reports of parental physical affection and parenting style: a study of Finnish twins

Individual differences in parenting behaviors are due, in part, to genetic factors. In the present study, the authors sought to determine whether the degree of genetic influence varied according to the type of parental behavior under consideration. A population-based sample of 2,334 pairs of Finnish twins provided ratings on the physical affection, control, abusiveness, and indifference shown by their father and mother during childhood. Genetic influences, shared environmental influences, and nonshared environmental influences accounted for a small-to-medium proportion (17%-30%), a small-to-large proportion (22%-44%), and a medium-to-large proportion (37%-55%) of the variance in each parenting measure, respectively. There were no significant differences in effect sizes for mothers and fathers or across the 4 types of parental behavior. The genetic results may reflect characteristic styles with which parents respond to genetically influenced behaviors of individuals (gene-environment correlations) or individual perceptions of this relationship (gene-person correlation processes). The findings have implications for intervention and prevention work with families and for interpretation of evidence for interactions between genes and parenting behaviors.     

A genetically informed study of associations between family functioning and child psychosocial adjustment

Research has documented associations between family functioning and offspring psychosocial adjustment, but questions remain regarding whether these associations are partly due to confounding genetic factors and other environmental factors. The current study used a genetically informed approach, the Children of Twins design, to explore the associations between family functioning (family conflict, marital quality, and agreement about parenting) and offspring psychopathology. Participants were 867 twin pairs (388 monozygotic; 479 dizygotic) from the Twin and Offspring Study in Sweden, their spouses, and children (51.7% female; M = 15.75 years). The results suggested associations between exposure to family conflict (assessed by the mother, father, and child) and child adjustment were independent of genetic factors and other environmental factors. However, when family conflict was assessed using only children's reports, the results indicated that genetic factors also influenced these associations. In addition, the analyses indicated that exposure to low marital quality and agreement about parenting was associated with children's internalizing and externalizing problems and that genetic factors also contributed to the associations of marital quality and agreement about parenting with offspring externalizing problems.     

瑞典的双生子与子代研究： 通过双生子及其家庭来增加对遗传与环境互动的了解

双生子及子代研究（TOSS）收集了909对双生子及他（她）们的配偶和他（她）们的青少年子女的数据。设计该项目是为研究以下三个问题：1）遗传与环境是如何影响双生子父母的养育方式的？2）遗传与环境是如何影响成年人的家庭关系的？3）家庭关系是如何影响成年人的心理调适的？由于此研究包括了双生子及其子女,该设计可以与其他研究相比较来具体地分析遗传与环境的关联。此研究的结果有助于厘清遗传与环境在养育方式和家庭关系中的型态,同时也澄清了父母亲个人特征是如何影响他（她）们的养育方式,以及父母的个体特征是如何帮助解释了遗传对家庭关系的影响。此研究今后将进一步分析遗传与环境的关联与互动,以及候选基因与环境的关联与互动     

Difficult temperament and negative parenting in early childhood: a genetically informed cross‐lagged analysis

A genetically informed longitudinal cross‐lagged model was applied to twin data to explore etiological links between difficult temperament and negative parenting in early childhood. The sample comprised 313 monozygotic (MZ) and dizygotic (DZ) twin pairs. Difficult temperament and negative parenting were assessed at ages 2 and 3 using parent ratings. Both constructs were interrelated within and across age (rs .34–.47) and showed substantial stability (rs .65–.68). Difficult temperament and negative parenting were influenced by genetic and environmental factors at ages 2 and 3. The genetic and nonshared environmental correlations (rs .21–.76) at both ages suggest overlap at the level of etiology between the phenotypes. Significant bidirectional associations between difficult temperament and negative parenting were found. The cross‐lagged association from difficult temperament at age 2 to negative parenting at age 3 and from negative parenting at age 2 and difficult temperament at age 3 were due to genetic, shared environmental, and nonshared environmental factors. Substantial novel genetic and nonshared environmental influences emerged at age 3 and suggest change in the etiology of these constructs over time.     

The Role of Peers in the Linkages Between Harsh Parenting and Mental Health Outcomes Among Adolescents from Families At-Risk

Harsh parenting is associated with adolescent mental health concerns. Peer relationships also importantly influence adolescent mental health outcomes. Although the direct associations between harsh parenting, peer relationships, and adolescent outcomes have been empirically established, less is known about the extent to which peer relationships mediate the associations between harsh parenting and adolescent outcomes. This study tested the links between harsh parenting, peer relationships, and adolescent outcomes among families at-risk for child maltreatment. With a sample of caregivers and adolescents (n = 218), the results of mediation analyses indicated that peer aggression partially mediated the pathway between harsh parenting and externalizing symptoms of both females and males. Additionally, peer rejection partially mediated the links between harsh parenting and internalizing symptoms of both females and males and peer rejection also was a partial mediator of male externalizing symptoms.     

Parental monitoring moderates the importance of genetic and environmental influences on adolescent smoking

Although there is a substantial literature on the role of parenting in adolescent substance use, most parenting effects have been small in magnitude and studied outside the context of genetically informative designs, raising debate and controversy about the influence that parents have on their children (D. C. Rowe, 1994). Using a genetically informative twin-family design, the authors studied the role of parental monitoring on adolescent smoking at age 14. Although monitoring had only small main effects, consistent with the literature, there were dramatic moderation effects associated with parental monitoring: At high levels of parental monitoring, environmental influences were predominant in the etiology of adolescent smoking, but at low levels of parental monitoring, genetic influences assumed far greater importance. These analyses demonstrate that the etiology of adolescent smoking varies dramatically as a function of parenting.     

Genetics and intelligence: Recent data

During the last three years, cognitive data have been reported for 4,639 pairings using the family design, 2,540 pairings using the adoption design, and 2,164 pairs of twins. Together, these extensive data point to less heritable influence on IQ than is indicated by the widely cited older data. The difference between the newer and older data could be due to environmental or genetic secular changes in the population or to methodological differences. Contrary to usual assumptions, the newer data also suggest that more of the environmental influences for parents and offspring and for older siblings operate within families (making family members different from one another) than between families (making family members similar to one another).     

青少年抑郁情绪的行为遗传学研究

本研究意在探讨青少年抑郁情绪遗传率的性别和年龄差异及遗传和环境对抑郁情绪跨时间连续性的影响。508对同卵双生子, 176对同性别异卵双生子参加了两轮追踪研究, 时间间隔约为一年半(1.37±0.44)。第一轮测量双生子的年龄范围为10~18岁, 平均年龄为13.69±2.04岁, 男生比例为46.2%。采用儿童抑郁量表(CDI)对青少年的抑郁情绪进行多报告者评定。结果发现, 青少年抑郁情绪的遗传解释率不存在性别差异, 处于青春早期青少年的遗传解释率高于青春中期的青少年。遗传是影响青春早期青少年抑郁情绪持续发生的主导因素, 而环境是影响青春中期青少年抑郁情绪持续发生的主要因素。     

School Context and Genetic Influences on Aggression in Adolescence

Genetic and environmental contributions to variation in aggression were examined using adolescents' self-reports of aggressive behavior. The National Longitudinal Study of Adolescent Health provided a sample of 1,515 pairs of adolescents in five genetically informative groups (i.e., monozygotic twins, dizygotic twins, full siblings, half siblings, and unrelated siblings reared together). The analysis, a DeFries-Fulker regression within a hierarchical linear model, yielded findings on individual-level heritability (h2), shared environmental effects (c2), school-level effects, and school-level moderation of h2 and c2. The estimate of h2 for aggression in the full sample was .32, and c2 was .05. In the moderating effect, h2 increased and c2 decreased with greater school-level family warmth. Two effects on school means were found: Those schools with greater ethnic-racial heterogeneity had higher mean levels of aggression, and schools where students perceived greater family warmth had lower mean levels of aggression.     

父母教养方式与青少年网络成瘾:自我弹性的中介和调节作用检验

对2758名初中生的父母教养方式、网络成瘾和自我弹性进行问卷测查,考察父母教养方式与青少年网络成瘾的关系及自我弹性在其中的作用。结果表明:(1)控制无关变量后,专制和纵容教养显著正向预测网络成瘾。(2)自我弹性在权威和专制教养与网络成瘾之间有中介作用。(3)自我弹性在专制教养与网络成瘾之间有调节作用,专制教养与网络成瘾的正向联系在高自我弹性个体中要比在低自我弹性个体中更明显。     

A behavior-genetic study of parenting quality, infant attachment security, and their covariation in a nationally representative sample

A number of relatively small-sample, genetically sensitive studies of infant attachment security have been published in the past several years that challenge the view that all psychological phenotypes are heritable and that environmental influences on child development--to the extent that they can be detected--serve to make siblings dissimilar. Using the twin subsample (N = 485 same-sex pairs) of the nationally representative Early Childhood Longitudinal Study-Birth Cohort, the authors provide evidence that parenting quality and infant attachment security observed at 24 months, as well as their covariation, are a product of shared and nonshared environmental (but not genetic) variation among children. In contrast, genetic differences between infants played a prominent role in explaining observations of temperamental dependency.     

Adolescent sibling differences in suicidal symptoms: The role of parent-child relationships

This study examined concordance for symptoms of suicide among 178 pairs of adolescent siblings, and the association of youth and maternal reports of parenting with variation in suicide ideation both across families and between siblings. Crosstabulation analyses indicated a significant risk of suicide ideation among siblings of adolescents who had made suicide attempts, as well as a significant degree of concordance for suicide ideation among pairs of siblings. Regression analyses indicated that reported levels of maternal warmth and harsh discipline, especially youth reports, were associated with suicide ideation, and that sibling differences on these parenting indices were associated with differences in suicide ideation both across families as well as between siblings. However, sibling differences in reported parenting did not contribute to prediction of suicide ideation above the variance accounted for by the simple levels of parenting reported by adolescents.     

Suicidal Ideation, Depression, and Conduct Disorder in a Sample of Adolescent and Young Adult Twins

The co-occurrence of suicidal ideation, depression, and conduct disturbance is likely explained in part by correlated genetic and environmental risk factors. Little is known about the specific nature of these associations. Structured interviews on 2,814 twins from the Virginia Twin Study of Adolescent Behavioral Development (VTSABD) and Young Adult Follow-Up (YAFU) yielded data on symptoms of depression, conduct disorder, and adolescent and young adult suicidal ideation. Univariate analyses revealed that the familial aggregation for each trait was explained by a combination of additive genetic and shared environmental effects. Suicidal ideation in adolescence was explained in part by genetic influences, but predominantly accounted for by environmental factors. A mixture of genetic and shared environmental influences explained ideation occurring in young adulthood. Multivariate analyses revealed that there are genetic and shared environmental effects common to suicidal ideation, depression, and conduct disorder. The association between adolescent suicidal ideation and CD was attributable to the same genetic and environmental risk factors for depression. These findings underscore that prevention and intervention strategies should reflect the different underlying mechanisms involving depression and conduct disorder to assist in identifying adolescents at suicidal risk.     

二孩家庭父母偏爱的特点及其与青少年抑郁的关系

对1655名来自二孩家庭的青少年进行调查,以考察二孩家庭中父母偏爱的特点及其与青少年抑郁的关系。结果发现：（1）父母偏爱水平较低,且父亲偏爱和母亲偏爱不存在显著差异。（2）父母偏爱存在性别和出生次序差异,男孩报告父母更偏爱自己,女孩报告父母更偏爱同胞;头胎子女报告父亲更偏爱自己,母亲更偏爱同胞,二胎子女则相反。（3）父母偏爱对青少年抑郁有显著影响,且为U型曲线关系,即当父母偏爱同胞或中高程度偏爱自己时,青少年抑郁水平均较高;当父母较低程度偏爱自己时,青少年抑郁水平最低。说明二孩家庭中不存在严重的父母偏爱,但父母偏爱会对青少年发展产生消极影响。     

Age differences in genetic and environmental influences on eating attitudes and behaviors in preadolescent and adolescent female twins

A sample of 680 11- and 602 17-year-old female twins was used to examine (a) age differences in genetic and environmental influences on disordered eating attitudes and behaviors and (b) associations between body mass index (BMI) and eating attitudes and behaviors. Univariate, biometrical model-fitting analyses indicated that 11-year-old twins exhibited less genetic and greater shared environmental influence on eating attitudes and behaviors than 17-year-old twins. Bivariate model-fitting analyses indicated that the relationship between BMI and eating attitudes was mediated primarily by common shared environmental influences in 11-year-old twins and common genetic influences in 17-year-old twins. Nonetheless, the majority of genetic influences on eating attitudes and behaviors in older twins were due to genetic effects that are independent of those operating in BMI.     

Genetic and Environmental Contributions to Common Psychopathologies of Childhood and Adolescence: A Study of Twins and Their Siblings

We report findings based on analyses of self-reports of six common adolescent psychopathologies (attention deficit/hyperactivity disorder, ADHD; conduct disorder, CD; oppositional defiant disorder, ODD; generalized anxiety disorder, GAD; separation anxiety disorder, SAD; and major depressive disorder, MDD) in a sample of 1,162 male and female adolescent (12–19 years) twin pairs and 426 siblings. Prevalence statistics for past year and lifetime reports confirm differences between genders for CD, GAD, SAD, and MDD, and a lack of differences between twins and their non-twin siblings. Biometrical modeling was conducted to ascertain the relative influences of genes, and shared and non-shared environments contributing to these disorders. A more robust estimate of these parameters was obtained by including non-twin siblings. Age-specific thresholds were integrated into the analyses to appropriately model the developmental patterns of behavior. We found evidence for both genetic and non-shared environmental influences for all disorders. Shared environmental influences also seem to be important for MDD and lifetime GAD.     

Parental criticism and externalizing behavior problems in adolescents: the role of environment and genotype-environment correlation

Genetic factors are important for the association between parental negativity and child problem behavior, but it is not clear whether this is due to passive or evocative genotype-environment correlation (rGE). In this study, we applied the extended children-of-twins model to directly examine the presence of passive and evocative rGE as well as direct environmental effects in the association between parental criticism and adolescent externalizing problem behavior. The cross-sectional data come from the Twin and Offspring Study in Sweden (N = 909 pairs of adult twins) and from the Twin Study of Child and Adolescent Development (N = 915 pairs of twin children). The results revealed that maternal criticism was primarily due to evocative rGE emanating from their adolescent's externalizing behavior. On the other hand, fathers' critical remarks tended to affect adolescent problem behavior in a direct environmental way. This suggests that previously reported differences in caretaking between mothers and fathers also are reflected in differences in why parenting is associated with externalizing behavior in offspring.     

多巴胺系统多基因与青少年攻击行为的U型关系：母亲消极教养的调节作用

多巴胺活性与攻击相关的脑功能活动呈倒U型关系。本研究对1044名汉族青少年(初次测评时M age=13.32±0.49岁,50.2%女生)的攻击行为进行间隔一年的两次测评,采用多基因累积分范式考察多巴胺系统的多基因功能积分与青少年攻击行为间的关系以及母亲消极教养的调节作用。结果发现,多巴胺系统多基因累积分二次项与母亲消极教养交互影响两个时间点的青少年攻击行为：在较高母亲消极教养条件下,携带较多或较少低多巴胺活性相关等位基因的青少年表现出高水平的攻击行为,呈U型关系;在较低母亲消极教养条件下,多基因累积分二次项与青少年的攻击行为关系不显著。本研究为多巴胺系统基因的联合效应与母亲消极教养调节青少年攻击行为的基因作用机制提供证据。     

多巴胺、5-羟色胺通路相关基因及家庭环境对创造力的影响及其作用机制

创造力的遗传基础是近年来创造力研究领域的前沿和热点问题, 但仍尚处于起步阶段, 也未有研究系统探讨遗传与环境因素的交互作用对创造力的影响及其作用机制。本课题拟在中国汉族人群中考察多巴胺(DA)、5-羟色胺(5-HT)神经递质通路上的32个基因约700个多态性位点与创造力的关系, 并首次探讨家庭环境在遗传多态性与创造力关系中的调节作用。研究内容包括：(1)通过单基因、基于通路以及基因—基因交互作用的关联分析, 考察遗传多态性对创造力的影响, 揭示创造力的遗传基础; (2)通过基因—环境交互作用的关联分析, 考察家庭环境在遗传与创造力关系中的调节作用; (3)通过结构方程模型的比较分析, 揭示遗传与家庭环境在创造力两个方面(创造思维与创造人格)共享的与特异的作用机制。该项目成果能够从遗传与环境交互作用的角度阐明创造力个体差异的原因, 有助于构建基于创造力个体差异分析的理论模型, 对创造人才的鉴别和培养具有重要现实意义。     

Religiousness, antisocial behavior, and altruism: genetic and environmental mediation

Although religiousness is considered a protective factor against antisocial behaviors and a positive influence on prosocial behaviors, it remains unclear whether these associations are primarily genetically or environmentally mediated. In order to investigate this question, religiousness, antisocial behavior, and altruistic behavior were assessed by self-report in a sample of adult male twins (165 MZ and 100 DZ full pairs, mean age of 33 years). Religiousness, both retrospective and current, was shown to be modestly negatively correlated with antisocial behavior and modestly positively correlated with altruistic behavior. Joint biometric analyses of religiousness and antisocial behavior or altruistic behavior were completed. The relationship between religiousness and antisocial behavior was due to both genetic and shared environmental effects. Altruistic behavior also shared most all of its genetic influence, but only half of its shared environmental influence, with religiousness.