Lateralized Increases in Cerebral Blood Flow during Performance of Verbal and Spatial Tasks: Relationship with Performance Level

Physiologic neuroimaging studies have shown lateralized regional increase in brain activity during cognitive tasks, but the hypothesis that such changes are correlated with task performance has not been tested directly. We examined cerebral blood flow (CBF) changes induced by cognitive tasks in relation to performance. CBF was measured with the ¹³³Xenon clearance method in 34 normal right-handed young (age < 30) volunteers during resting baseline and during the performance of a verbal analogies and a spatial line orientation test. Performance measures included "speed" and "power" estimates of both activation tasks. Resting CBF was moderately correlated with performance. The correlations were slightly higher with activated CBF for verbal but not spatial performance. The degree of increase (task-baseline) did not correlate with performance for either task. The highest and topographically specific correlations were obtained between laterality of CBF and verbal performance. Higher left hemispheric activation was correlated with verbal performance, and this correlation was significantly higher in the angular gyrus region. For the spatial task the correlations were with relatively higher right hemispheric activation but without regional specificity. The results underscore the importance of integrating behavioral performance data with physiologic measures in neuroimaging activation studies.     

Suppression of Regional Cerebral Blood during Emotional versus Higher Cognitive Implications for Interactions between Emotion and Cognition

Brain mapping studies using dynamic imaging methods demonstrate areas regional cerebral blood flow (rCBF) decreases, as well as areas where increases, during performance of various experimental tasks. Task holds for both sets of cerebral blood flow changes (CBF), providing the opportunity to investigate areas that become and “activated” in the experimental condition relative to control state. Such data yield the intriguing observation that in areas in emotional processing, such as the amygdala, the posteromedial cortex, and the ventral anterior cingulate cortex, although flow as expected during specific emotion-related tasks, flow decreases performance of some attentionally demanding, cognitive tasks. Conversely, in some of the areas that appear to subserve cognitive functions, as the dorsal anterior cingulate and the dorsolateral prefrontal cortices, increases while performing attentionally demanding cognitive tasks, but during some experimentally induced and pathological emotional Although the specific nature of such reciprocal patterns of regional remains unclear, they may reflect an important cross-modal interaction during mental operations. The possibility that neural activity is less in areas required in emotional processing during some higher cognitive processes holds implications for the mechanisms underlying interactions cognition and emotion. Furthermore, the possibility that neural in some cognitive-processing areas is suppressed during intense states suggests mechanisms by which extreme fear or severe may interfere with cognitive performance.     

Perseveration in Normal Aging: A Comparison of Perseveration Rates on Design Fluency and Verbal Generative Tasks

Three generative tasks (design generation, animal naming, words starting with m) from the Cognitive Linguistic Quick Test were administered to 73 healthy individuals in four age groups (18–39, 40–59, 60–74, 75–88) and scored for perseveration and productivity. Perseveration rates for design generation were significantly higher, and increased linearly as a function of age. The number of individuals who perseverated at least once on design generation also increased linearly, with highest prevalence in the oldest group. No age effects were found for perseveration on the verbal naming tasks. Perseverations across tasks were independent of one another. The design generation task may require multiple simultaneous processing skills, placing more demand on compromised executive processing in the elderly.     

Embodied Information in Cognitive Tasks: Haptic Weight Sensations Affect Task Performance and Processing Style

Research in the field of embodied cognition showed that incidental weight sensations influence peoples’ judgments about a variety of issues and objects. Most studies found that heaviness compared to lightness increases the perception of importance, seriousness, and potency. In two experiments, we broadened this scope by investigating the impact of weight sensations on cognitive performance. In Experiment 1, we found that the performance in an anagram task was reduced when participants held a heavy versus a light clipboard in their hands. Reduced performance was accompanied by an increase in the perceived effort. In Experiment 2, a heavy clipboard elicited a specific response heuristic in a two-alternative forced-choice task. Participants showed a significant right side bias when holding a heavy clipboard in their hands. After the task, participants in the heavy clipboard condition reported to be more frustrated than participants in the light clipboard condition. In both experiments, we did not find evidence for mediated effects that had been proposed by previous literature. Overall, the results indicate that weight effects go beyond judgment formation and highlight new avenues for future research.     

Real‐World Correlates of Performance on Heuristics and Biases Tasks in a Community Sample

In the current study, we sought to examine whether performance on several heuristics and biases tasks and thinking dispositions was associated with real‐life correlates in a community sample of adults. We examined performance on five heuristics and biases tasks (ratio bias, belief bias in syllogistic reasoning, cognitive reflection, probabilistic and statistical reasoning, and rational temporal discounting), three thinking dispositions (actively open‐minded thinking, future orientation, and avoidance of superstitious thinking), and a questionnaire assessing real‐world correlates in several domains (substance use, driving behavior, financial behavior, gambling behavior, electronic media use, and secure computing). Our heuristics and biases tasks and thinking disposition measures were modestly associated with several real‐world outcomes, including the domains of secure computing, financial behaviors, and the total scores. That is, better performance on the heuristics and biases measures was associated with fewer negative outcomes. We found that the associations were generally higher in males than in females. Heuristics and biases performance and thinking dispositions were unique predictors of real‐world outcomes after statistically controlling for educational attainment and sex differences. Copyright © 2016 John Wiley & Sons, Ltd.     

Facial Emotion Recognition in Autism Spectrum Disorders: A Review of Behavioral and Neuroimaging Studies

Behavioral studies of facial emotion recognition (FER) in autism spectrum disorders (ASD) have yielded mixed results. Here we address demographic and experiment-related factors that may account for these inconsistent findings. We also discuss the possibility that compensatory mechanisms might enable some individuals with ASD to perform well on certain types of FER tasks in spite of atypical processing of the stimuli, and difficulties with real-life emotion recognition. Evidence for such mechanisms comes in part from eye-tracking, electrophysiological, and brain imaging studies, which often show abnormal eye gaze patterns, delayed event-related-potential components in response to face stimuli, and anomalous activity in emotion-processing circuitry in ASD, in spite of intact behavioral performance during FER tasks. We suggest that future studies of FER in ASD: 1) incorporate longitudinal (or cross-sectional) designs to examine the developmental trajectory of (or age-related changes in) FER in ASD and 2) employ behavioral and brain imaging paradigms that can identify and characterize compensatory mechanisms or atypical processing styles in these individuals.     

Recognition of Affective Speech Prosody and Facial Affect in Deaf Children with Unilateral Right Cochlear Implants

Cochlear implant (CI) devices provide the opportunity for children who are deaf to perceive sound by electrical stimulation of the auditory nerve, with the goal of optimizing oral communication. One part of oral communication concerns meaning, while another part concerns emotion: affective speech prosody, in the auditory domain, and facial affect, in the visual domain. It is not known whether childhood CI users can identify emotion in speech and faces, so we investigated speech prosody and facial affect in children who had been deaf from infancy and experienced CI users. METHOD: Study participants were 18 CI users (ages 7–13 years) who received right unilateral CIs and 18 age- and gender-matched controls. Emotion recognition in speech prosody and faces was measured by the Diagnostic Analysis of Nonverbal Accuracy. RESULTS: Compared to controls, children with right CIs could identify facial affect but not affective speech prosody. Age at test and time since CI activation were uncorrelated with overall outcome measures. CONCLUSION: Children with right CIs recognize emotion in faces but have limited perception of affective speech prosody.     

Cerebral blood flow in 5‐ to 8‐month‐olds: Regional tissue maturity is associated with infant affect

Infancy is marked by rapid neural and emotional development. The relation between brain function and emotion in infancy, however, is not well understood. Methods for measuring brain function predominantly rely on the BOLD signal; however, interpretation of the BOLD signal in infancy is challenging because the neuronal‐hemodynamic relation is immature. Regional cerebral blood flow (rCBF) provides a context for the infant BOLD signal and can yield insight into the developmental maturity of brain regions that may support affective behaviors. This study aims to elucidate the relations among rCBF, age, and emotion in infancy. One hundred and seven mothers reported their infants' (infant age M ± SD = 6.14 ± 0.51 months) temperament. A subsample of infants completed MRI scans, 38 of whom produced usable perfusion MRI during natural sleep to quantify rCBF. Mother‐infant dyads completed the repeated Still‐Face Paradigm, from which infant affect reactivity and recovery to stress were quantified. We tested associations of infant age at scan, temperament factor scores, and observed affect reactivity and recovery with voxel‐wise rCBF. Infant age was positively associated with CBF in nearly all voxels, with peaks located in sensory cortices and the ventral prefrontal cortex, supporting the formulation that rCBF is an indicator of tissue maturity. Temperamental Negative Affect and recovery of positive affect following a stressor were positively associated with rCBF in several cortical and subcortical limbic regions, including the orbitofrontal cortex and inferior frontal gyrus. This finding yields insight into the nature of affective neurodevelopment during infancy. Specifically, infants with relatively increased prefrontal cortex maturity may evidence a disposition toward greater negative affect and negative reactivity in their daily lives yet show better recovery of positive affect following a social stressor.     

The “dual usage problem” in the explanations of “joint attention” and children’s socioemotional development: A reconceptualization

The term “joint attention”, which first gained currency in the early 1960s in studies of the development of language and symbolic thought, remains significant in the developmental literature. However, its meaning is unclear. A definitional problem exists similar to what Patterson [Patterson, M. L. (1982). A sequential functional model of nonverbal exchange. Psychological Review, 89, 231–249] described as the “dual usage” problem in the study of behaviour. The dual usage problem manifests when the behaviours of interest are used interchangeably with the function served by those behaviours. Similarly, the behaviours or skills that are taken to show joint attention are used interchangeably with the functions served by these behaviours. Scant attention is given to how the behaviours are generated and regulated and how they contribute to development. The purpose of the present position paper was: (1) to identify and illustrate the ways in which the behaviours and functions of joint attention have been confounded in the literature; (2) to provide a revised operationalization of joint attention incorporating the idea of Consummative Joint Attention, which is defined as a process variable that integrates these two theoretically different and complementary aspects of “joint attention;” and (3) to test this revised definition with evidence from a sample of hearing mothers and their 18- to 36-month-old hearing or deaf toddlers. We suggest that a reconceptualization and revised definition of joint attention as a process served by a particular sequence of complementary and well-timed events in the behaviour of mother–child interaction are particularly well-suited to testing joint attention as an early prelingual mechanism and to detecting early problems with psychosocial and adaptive development created by ineffective patterns of social interaction.     

Aging,Task Complexity,and Efficiency Modes: The Influence of Working Memory Involvement on Age Differences in Response Times for Verbal and Visuospatial Tasks

ABSTRACT

We examined the information-processing functions (response-time × load) of younger and older adults for two verbal and one visuo-spatial task; each task was implemented in a baseline and a high-complexity condition. Heightened complexity transformed the baseline functions in either an additive or a multiplicative fashion. The processing efficiency of older adults was defined as the old-young ratio of the slopes of the load functions. Three levels of efficiency could be distinguished. The first level, with an age-related slowing factor of about 1.2, consisted of low-complexity verbal processing and additive-complexity verbal processing. The second level, associated with a slowing factor of about 1.6, consisted of a mixture of verbal-high-multiplicative-complexity processing and visuo-spatial-low-complexity processing. The third level, with a slowing factor of about 4, consisted of visuo-spatial processing of high multiplicative complexity. The results go against any common factor theory of aging. Instead, they suggest that a shift from a higher to a lower mode of efficiency is triggered by a greater degree of working memory involvement.     

Self-Talk in the Swimming Pool: The Effects of Self-Talk on Thought Content and Performance on Water-Polo Tasks

The present study examined the effect of instructional and motivational self-talk on the occurrence of interfering thoughts and performance on two water-polo tasks with similar characteristics performed in the same environment. Two experiments were conducted in the swimming pool, one involving a precision task (throwing a ball at target) and one involving a power task (throwing a ball for distance). In the first experiment (precision task), both self-talk groups improved their performance in comparison to the baseline measure, with participants using instructional self-talk improving more. In the second experiment (power task), only the motivational self-talk group improved its performance significantly. In both experiments the occurrence of interfering thoughts declined for both groups. The results of the study provide further support for the effectiveness of self-talk and give preliminary evidence regarding likely mechanisms through which self-talk influence performance, that is through indications that self-talk reduces thoughts not related to task execution, thus enhancing concentration to the task.     

The Role of Dichotic Listening Performance and Tasks of Executive Functions in Reading Impairment: A Discriminant Function Analysis

This study focused on the role of dichotic listening performance for the identification of reading impaired subtypes. Dichotic listening (DL), using verbal stimuli, has shown to be a valid measure of language lateralization. Usually, lateralization is estimated from the proportion of right ear over left ear accuracy during a free recall test procedure. However, it has been suggested that a more accurate estimate of laterality can be obtained by using a directed attention procedure. A sample of 43 reading disabled children of whom 18 showed signs of impaired language comprehension skills and 25 without language comprehension impairments, were compared to 20 age, and gender, matched controls on dichotic listening performance in both an unbiased free recall task and in a directed attention task using consonant-vowel syllables as dichotic stimuli. A laterality index was calculated for left and right ear stimuli reported during both the free recall condition and the attended ear-scores for the two directed attention conditions. Although both DL procedures yielded significant group differences, with a lower laterality score for the reading disabled compared to the controls, there was no main effect of DL-procedure or group × procedure interaction. Taken alone, DL performance could correctly classify 42% of the reading impaired samples, but together with other measures of executive functions, discriminant function analyses yielded 90.74% accuracy in classifying reading impaired children. The result indicates that DL together with tests of executive functions are valuable tools for assessment of reading impaired subjects.     

Developmental Changes in Semantic Verbal Fluency: Analyses of Word Productivity as a Function of Time,Clustering, and Switching

We investigated age-related improvement in semantic category verbal fluency (VF) in 309 Dutch schoolchildren attending first to ninth grade. Quantitative analyses of number of correct responses as a function of time as well as qualitative analyses of clustering and switching were conducted. Overall, Dutch VF task performance, i.e., number of correct responses over 60 seconds, was not established before mid-adolescence. This is in line with previously published studies, using VF number of correct responses over 60 seconds as the main outcome measure and examining VF task performance across other cultures and languages (e.g., Italian, French, Hebrew). Next, mean cluster size, a measure of lexico-semantic knowledge, was not established until at least grade 3. In contrast, performance on the VF outcome measures “number of switches/clusters” was established at least 4 years later. Qualitative and quantitative Design Fluency (DF) outcome measures support the notion that the numbers of switches/clusters are valid measures of higher order cognitive functions, such as strategy use and cognitive flexibility. In line of this, VF number of correct responses during 16–60 seconds, a measure of controlled information processing, is established at least 2 years later (i.e., grades 7–8) than number of correct responses during the first 15 seconds time slide, a measure of automatic processing. Finally, environment, i.e., the level of parental education, primarily affected automatic and lexico-semantic knowledge. No effects of sex on VF performance were found. These data suggest that the alternative scoring methods of VF tasks can be used to acquire knowledge on development of lower and higher order cognitive functions in healthy children and the influence of the environment on it.     

Putting the “IRT” in “Dirty”: Item response theory analyses of the Dark Triad Dirty Dozen—An efficient measure of narcissism,psychopathy, and Machiavellianism

The Dark Triad Dirty Dozen is a new, concise personality inventory designed to measure individual differences in narcissism, psychopathy, and Machiavellianism in sub-clinical populations. To date, the psychometric work on this measure has used classical test theory to assess its validity, reliability, and structure. In two independent samples (N = 1014), we provide the first analyses of this measure using item response theory. In both samples, the Dark Triad Dirty Dozen efficiently recovered information and showed some evidence of differential scale functioning by sex, with a lower endorsement threshold for men compared to women. Results shed new light on the measurement of these “dark” personality traits.     

“What I did” versus “what I might have done”: Effect of factual versus counterfactual thinking on blame, guilt, and shame in prisoners

The present study tested the prediction that counterfactual thinking would have a stronger amplificatory effect on guilt than on shame and that the effect would be mediated by self-blame. Ninety sentenced prisoners were instructed to think either counterfactually or factually about the role they played in the events leading to their capture, conviction, and sentencing prior to reporting on their level of self-blame, guilt, and shame. Compared to factual-focused prisoners, counterfactual-focused prisoners reported feeling more blameworthy and guiltier but not more shameful. The effect of thought focus on guilt was fully mediated by blame. The findings support an emotion-specific account of the emotional consequences of counterfactual thinking that implicate attributional judgment as an important mediating process.     

慢性乙型肝炎患者外周血中睾酮的变化及其意义

测定65例慢性乙型肝炎患者和35例健康者血清睾酮水平,并分别检测血清丙氨酸氨基转移酶（alanine aminotransferase,ALT）、谷氨酸氨基转移酶（aspartate aminotransferase,AST）、γ-谷氨酰基转肽酶（gamma-glutamyl transpeptidase,GOT）、血清总胆红素（total bilirubin,TBIL）、碱性磷酸酶（alkaline phosphatase,ALP）、免疫球蛋白IgG、IgM、IgA,荧光定量PCR检测外周血HBV DNA水平。慢性乙型肝炎患者血清睾酮水平显著高于正常对照组,HBeAg阳性患者较HBeAg阴性患者升高明显,但差别无显著意义。慢性乙型肝炎患者肝功血清学指标ALT、AST、TBIL、GGT、ALP及IgG水平显著高于正常人,但乙肝患者睾酮水平与ALT等生化指标及HBV DNA水平无明显相关性,与免疫球蛋白IgG呈中等负相关。因而可以看出慢性乙型肝炎患者血清睾酮水平显著高于正常人,睾酮水平升高可作为慢性乙型肝炎的易感因素之一。     

The “Sprinter effect”: When self-control and involvement stand in the way of sequential performance

This research examines the joint effect of dispositional self-control and situational involvement on performance in two successive resource-demanding tasks. We demonstrate that being highly involved and having high self-control facilitates high performance in the first task but, contrary to intuition, may jeopardize performance in a second, unexpected task. We term this the “sprinter effect” and demonstrate it in both lab and field settings. We further explore how a “marathon” mindset can debias this effect.