Running is the neurogenic and neurotrophic stimulus in environmental enrichment

Environmental enrichment (EE) increases dentate gyrus (DG) neurogenesis and brain-derived neurotrophic factor (BDNF) levels. However, running is considered an element of EE. To dissociate effects of physical activity and enrichment on hippocampal neurogenesis and BDNF levels, young female C57Bl/6 mice were housed under control, running, enrichment, or enrichment plus running conditions, and injected with bromodeoxyuridine. Cell genesis was assessed after 12 d and differentiation was analyzed 1 mo later. In addition, locomotor activity in the open field and hippocampal mature BDNF peptide levels were measured. Open-field adaptation was improved in all groups, compared to controls, but more so with running. New cell proliferation, survival, neuron number, and neurotrophin levels were enhanced only when running was accessible. We conclude that exercise is the critical factor mediating increased BDNF levels and adult hippocampal neurogenesis.     

Sports participation outside school in total physical activity of children

This study of associations of sports participation with perceived and actual physical fitness, and total physical activity for 525 10- to 17-yr.-old boys and girls in groups of 10-11-yr. (56 boys and 64 girls), 12-13-yr. (68 boys and 68 girls), 14-15-yr. (70 boys and 71 girls), and 16-17-yr. (68 boys and 60 girls) was based on the Physical Activity Index derived from a questionnaire by Telama, Leskinen, and Young, and self-perceived endurance, strength, flexibility, and body composition. Questions about satisfaction with physical activity, participation in organized physical activity and competitions, or watching competitions were asked. Two EUROFIT tests were used, the 20-m endurance shuttle-run and sit-and-reach, plus the sum of 9 skinfold thicknesses. Children who participated in organized physical activity and in competitions had a higher Physical Activity Index. Passive watching of competitions was not related to children's physical activity or their perceived or measured motor abilities.     

Immediate post intervention effects of two brief youth suicide prevention interventions

This study evaluated the immediate postintervention effects of two brief suicide prevention protocols: a brief interview--Counselors CARE (C-CARE)--and C-CARE plus a 12-session Coping and Support Training (CAST) peer-group intervention. Subjects were students "at risk" of high school dropout and suicide potential in Grades 9-12 from seven high schools (N = 341). Students were assigned randomly to C-CARE plus CAST, C-CARE only, or "intervention as usual." The predicted patterns of change were assessed using trend analyses on data available from three repeated measures. C-CARE and CAST led to increases in personal control, problem-solving coping, and perceived family support. Both C-CARE plus CAST and C-CARE only led to decreases in depression, and to enhanced self-esteem and family goals met. All three groups showed equivalent decreases in suicide risk behaviors, anger control problems, and family distress.     

Asparagus recemosus enhances memory and protects against amnesia in rodent models

Asparagus Racemosus (AR) is an Ayurvedic rasayana possessing multiple neuropharmacological activities. The adpatogenic and antidepressant activity of AR is well documented. The present study was undertaken to assess nootropic and anti-amnesic activities of MAR in rats. The Morris water maze (MWM) and elevated plus maze (EPM) models were employed to evaluate learning and memory activity. Subsequently, the anti-amnestic activity was evaluated in scopolamine and sodium nitrite (NaNO₂)-induced amnestic models in rats. Rats pre-treated with MAR (50, 100 and 200 mg/kg, p.o) for 7 days showed significant decrease in escape latency in the MWM test indicating nootropic activity. MAR also significantly reversed scopolamine and sodium nitrite-induced increase in transfer latency on EPM indicating anti-amnesic activity. Further, MAR dose-dependently inhibited acetylcholinesterase enzyme in specific brain regions (prefrontal cortex, hippocampus and hypothalamus). Thus, MAR showed nootropic and anti-amnesic activities in the models tested and these effects may probably be mediated through augmentation of cholinergic system due to its anti-cholinesterase activity.     

Evaluating adult interaction during the Step It UP! game to increase physical activity in children

A recent intervention, the Step it UP! game (Galbraith & Normand, 2017), consists of an interdependent group contingency to increase student physical activity. In addition, previous research demonstrated that adult interaction may reinforce physical activity (Larson et al., 2014). We extended research on the Step it UP! game by comparing the effects of no game, Step it UP! game, and Step it UP! game plus adult interaction on the number of steps taken by participants in a third-grade classroom during recess. Overall, 19 of the 25 participants took more steps during the Step it UP! game plus adult interaction compared to the Step it UP! game and no-game recesses. Furthermore, 20 participants preferred the Step it UP! game plus adult interaction. Results suggest that adult interaction can enhance the effects of the Step it UP! game to increase physical activity.     

A primer for advancing psychology in the public-sector

Psychologists working in the public sector should, in addition to providing direct services, advocate for systems change. Although many consumers treated in the public sector face a constellation of severe life problems, working to improve the system of care is more difficult than providing treatment. Improving the quality of life of consumers of publicly funded mental health services requires that psychologists become advocates. Four prerequisites to systems change, plus coalition building, legislative advocacy, the work of state psychological associations, and forming alliances between psychologists and nonpsychological community organizations such as Rotary International, are described. In conclusion, 12 orienting ideas are listed for psychologists who want to advocate for social, institutional, and political change.     

Influence of immobilization stress on the phospholipid composition of alveolar surfactant and lungs in rats

The influence of immobilization stress on the lipid composition of alveolar surfactant and lungs in rats immobilized for 12 and 24 hours, the effects of phospholipase A2, and lipid transfer activity in alveolar surfactant were investigated. The results indicate that alveolar surfactant phospholipids underwent more significant alterations compared to lung phospholipids. Furthermore, phospholipase A2 and lipid transfer activity were reduced in alveolar surfactant of immobilized rats. The reported data suggest that the lower lipid transfer activity might be responsible for the reduced phospholipids in the surfactant system.     

EVALUATING STRATEGIES TO IMPROVE CAREPROVIDER PERFORMANCE ON HEALTH AND DEVELOPMENTAL TASKS IN AN INFANT CARE FACILITY

Responding to administrative staff and parental concerns, using modified reversal and withdrawal designs, two experiments evaluated a staff-managed feedback system to improve the hygiene and developmental skills of children in an infant/toddler center. Experiment 1 examined feedback designed to increase staff performance in checking and changing diapers, and recording those changes. A chart plus supervisory feedback produced increases in and maintenance of staff performance. Experiment 2 compared an existing staff management system with a “playchart” plus feedback in increasing careprovider-infant stimulation. The data (with follow-up on a new staff) supported the use of the new feedback system. Questionnaire data further supported the utility of the playchart system.     

Bulimia nervosa: group behavior therapy with exposure plus response prevention

Exposure plus response prevention has been demonstrated to be effective in the treatment of bulimia nervosa. However, when done individually, it is labor intensive and cost-ineffective. In the present study exposure plus response prevention was used in the context of a 6-wk., 12-session behavioral group. In addition to the exposure plus response-prevention component, other techniques included self-monitoring, cognitive restructuring, eating-habit stabilization and problem-solving. Eight bulimic women, vomiting a minimum of five times per week for at least a year, participated in the group. At the end of treatment significant reductions in bingeing and vomiting behaviors were reported by all but one subject, substantiated by significantly lower depression scores (Beck Depression Inventory) and binge-eating scores (Binge Eating Scale). At 6 mo. and 1 yr. posttreatment, 6 of 8 subjects reported averaging less than one binge-purge episode per week, one subject continued unchanged, and one subject had relapsed. A group of wait-list control subjects reported essentially no change in binge-purge frequency over the treatment period. Exposure plus response prevention conducted in a behavioral group context appears to be a cost-effective alternative to individual treatment.     

A psychophysical measure of visual and kinaesthetic spatial discriminative abilities of adults and children

Quantitative estimates of the spatial discriminative capacities of the visual and kinaesthetic systems in adults and children were obtained. Intersensory integration was investigated by including spatial discriminations based on congruent visual plus kinaesthetic reafference. The psychophysical method of adjustment was used with simultaneous comparisons of a fixed and a variable stimulus. The subject's task was to estimate when the variable stimulus (ellipse) was identical to the standard one (circle), under one of three modality conditions: vision, kinaesthesis, and vision plus kinaesthesis. After a pilot study with adults, children (aged 8, 10, and 12 years) and adults were both tested. Subjects from each age group were randomly allocated to each of the three experimental conditions. Results show that the visual and kinaesthetic estimates of the 8- and 10-year-old subjects did not differ significantly, but the visual responses of the adults and 12 year olds were significantly more accurate than corresponding kinaesthetic estimates. Bisensory estimates were significantly more accurate than visual responses only for the 8- and 10-year-old age groups. Intramodal comparisons showed the kinaesthetic estimates of the 8, 10, and 12 year olds to be significantly more accurate than the corresponding adult performance. Adult visual estimates were significantly more accurate than those made by 8 year olds, but were not significantly different from the visual responses of 10 and 12 year olds. Estimates based on bisensory reafference did not differ from each other across the four age groups. It is concluded that modality adeptness and dominance are task dependent and empirically determined rather than being innate properties of sensory systems. The data indicate that intersensory differentiation rather than integration occurs with maturity.     

Ubiquitous Personality-Trait Concepts in 13 Diverse and Isolated Languages: A Cluster–Classification Approach

There is longstanding interest in the generalizability of personality across diverse cultures. To investigate the generalizability of personality concepts, we examined the English translations of individual-difference entries from the dictionaries of 12 small-scale societies previously studied for ubiquity of individual differences plus the dictionary of an additional society not previously studied in this manner. These 13 societies are highly diverse in geographical location, culture, and language family; their languages developed in isolation from modern-world languages. The goal of our exploratory research was to discover ubiquitous personality concepts in these 13 independent societies and their languages, providing a window into personality concepts across a broad range of cultures and languages. This study used clusters of empirically related terms (e.g. brave, courageous, and daring), based on a taxonomy of English-language personality concepts that consisted of 100 personality-trait clusters. English-language definitions of dictionary entries from the 13 languages were matched to the meanings of the synonym clusters. The cluster–classification method uncovered nine ubiquitous personality concepts, plus six that were present in at least 12 of the 13 languages. The nine ubiquitous personality concepts include some not previously identified and suggest a core of possibly universal concepts. © 2020 European Association of Personality Psychology     

INDUSTRIAL SAFETY HAZARD REDUCTION THROUGH PERFORMANCE FEEDBACK

A “feedback package” system, designed to prevent occupational accidents and to fit directly into the normal operations of an industrial organization, was analyzed. Eighteen hazardous conditions in six production departments were assessed during seven observation sessions over a 12-week period, plus four follow-up observations over 4 months. The “feedback package” was presented in multiple baseline fashion, across subjects (department supervisors). It consisted of presenting the supervisor with copies of observational data, accompanied by a note which congratulated good practices and suggested ways for improving safety conditions, along with occasional comments from a senior executive. The results indicated that during the feedback phase, hazard rates were lower and less variable than during the baseline phase. Baseline data were highly variable with peaks ranging from 20 to 55 hazards per department. Following intervention, hazard frequencies dropped by 60%, averaged across departments, with decreases ranging from 29% to 88%. During treatment, data stabilized, with the highest frequency reaching 33. A modified feedback system was implemented by the organization following termination of the study, validating the assumption that such a system would tend to maintain.     

Ongoing physical activity advice by humans versus computers: the Community Health Advice by Telephone (CHAT) trial.

PURPOSE: Given the prevalence of physical inactivity among American adults, convenient, low-cost interventions are strongly indicated. This study determined the 6- and 12-month effectiveness of telephone interventions delivered by health educators or by an automated computer system in promoting physical activity. DESIGN: Initially inactive men and women age 55 years and older (N = 218) in stable health participated. Participants were randomly assigned to human advice, automated advice, or health education control. MEASURES: The validated 7-day physical activity recall interview was used to estimate minutes of moderate to vigorous physical activity. Physical activity differences by experimental arm were verified on a random subsample via accelerometry. RESULTS: Using intention-to-treat analysis, at 6 months, participants in both interventions, although not differing from one another, showed significant improvements in weekly physical activity compared with controls. These differences were generally maintained at 12 months, with both intervention arms remaining above the target of 150 min per week of moderate to vigorous physical activity on average. CONCLUSION: Automated telephone-linked delivery systems represent an effective alternative for delivering physical activity advice to inactive older adults.     

Intraseptal Flumazenil Enhances, while Diazepam Binding Inhibitor Impairs, Performance in a Working Memory Task

GABA_A/benzodiazepine receptors in the medial septum modulate the activity of cholinergic neurons that innervate the hippocampus. Injection of benzodiazepine (BDZ) agonists into the medial septum impairs working memory performance and decreases high-affinity choline transport (HAChT) in the hippocampus. In contrast, intraseptal injection of the BDZ antagonist flumazenil increases HAChT and prevents the memory deficits induced by systemic BDZs. The present studies attempted to further characterize the behavioral effects of medial septal injections of flumazenil to an endogenous negative modulator of the GABA_A/BDZ receptor complex, diazepam binding inhibitor (DBI). Male Sprague–Dawley rats were cannulated to study the effects of intraseptal injections of these BDZ ligands on spatial working memory, anxiety-related behaviors in the elevated plus maze, and on general locomotor activity. Intraseptal flumazenil (10 nmol/0.5 μl) produced a delay-dependent enhancement of DNMTS performance after an 8-h, but not a 4-h, delay interval. This promnestic dose of flumazenil had no effect on locomotor activity and did not produce changes in measures of anxiety on the plus maze. Intraseptal injection of DBI had no effect (8 nmol/0.5 μl) or slightly impaired (4 nmol/0.5 μl) DNMTS radial maze performance following an 8-h delay, without producing changes in locomotion or plus maze behavior. These data demonstrate that flumazenil has a unique profile of activity in enhancing working memory following intraseptal injection.     

Two-Mode Models of Self-Regulation as a Tool for Conceptualizing Effects of the Serotonin System in Normal Behavior and Diverse Disorders

ABSTRACT— The serotonin system is a collection of neural pathways whose overall level of functioning (from low to high) relates to diverse kinds of psychological and behavioral variability. Individual differences in serotonergic function are important both in personality and in vulnerability to psychological disorders. These disorders range widely—from impulsive aggression to depression. One way to understand such diverse reflections of differences in serotonergic function is by viewing serotonergic function through the lens of two-mode (or dual-process) models of self-regulation. Such theories posit a lower-order system that responds quickly to associative cues of the moment and a higher-order system that responds reflectively and planfully. Low serotonergic function appears to enhance influence of the lower-order system. This often yields impulsive reactivity. Why, then, does low serotonergic function also relate to depression, which is characterized by lethargy and unresponsiveness? The answer must be that ascendance of the lower system interacts with other factors. One hypothesis is that low serotonergic function plus high sensitivity to incentives yields vulnerability to impulsive approach, whereas low serotonergic function plus low incentive sensitivity yields vulnerability to depression. Conceptualizing serotonergic function this way helps integrate information pertaining to very different disorders into a coherent picture.     

TREATING OVERWEIGHT CHILDREN THROUGH PARENTAL TRAINING AND CONTINGENCY CONTRACTING1

Fifteen overweight girls aged 5 to 11 yr were randomly assigned to one of two weight-reduction treatments: response-cost plus reinforcement, response-cost only, or a no-treatment control group. In the response-cost plus reinforcement group, parents contracted to facilitate their child's weight loss by carrying out reinforcement and stimulus control techniques, completing weekly charts and graphs, and encouraging their child to exercise. The response-cost only group parents did not contract to reinforce their child's performance. The response-cost program applied to both experimental groups was conducted in weekly meetings in which parents lost previously deposited sums of money. Twenty-five per cent was deducted for missing the weekly meeting, 25% for failing to fill out charts and graphs, and 50% if their child failed to meet her specified weekly weight-loss goal. At the end of the 12-week treatment period, both experimental groups had lost significantly more weight than the control group. After an eight-week, no-contact follow-up, some of the lost weight was regained. The response-cost plus reinforcement group was still significantly below the controls. The response-cost group just missed significance. A 31-week, no-contact follow-up failed to show a treatment effect, but did show a trend towards slower weight gain by the response-cost plus reinforcement group.     

舒芬太尼复合曲马多用于幼儿开胸术后静脉自控镇痛的临床观察

在择期开胸术后4h、8h、12h、24h、48h,通过对年龄为1岁～3岁的幼儿术后应用舒芬太尼联合曲马多或单纯舒芬太尼行静脉持续镇痛、镇静效果及恶心、呕吐、呼吸抑制等不良反应发生率对比观察,结果发现舒芬太尼复合曲马多用于幼儿开胸术后静脉镇痛,效果满意,安全性高,不良反应发生率低。     

Moderators of the benefits of psychoeducational interventions for men with prostate cancer.

The authors examined whether 3 individual difference variables--self-esteem, self-efficacy, and depressive symptoms--interacted with psychoeducational group interventions for men with prostate cancer (n = 250) to predict general and prostate-specific quality of life. Men with nonmetastatic prostate cancer were randomly assigned to an education intervention, an education plus group discussion intervention, or usual care and followed for 12 months. Eight groups of 10 to 12 men were convened in each condition. Men who began the study with lower self-esteem, lower prostate-specific self-efficacy, and higher depressive symptoms benefited the most from the interventions. Of these 3 moderator variables, the most consistent results emerged for self-esteem. That is, the benefits of the intervention were strongest for men with low self-esteem.     

Unconditioned sexual incentive motivation in the male Norway rat (Rattus norvegicus)

Sexual incentive motivation was evaluated in a procedure consisting of a large open field where incentive animals were confined behind wire mesh openings. When sexually inexperienced male rats (Rattus norvegicus) were exposed to the receptive female-male incentives, they spent more time close to the female. If the incentives were receptive female-nonreceptive female, the receptive female was preferred. However, when the alternatives were nonreceptive female-male, no preference was obtained. Castration abolished preference for the receptive female, and treatment with testosterone propionate restored it. Estradiol plus oil is as efficient as estradiol plus progesterone for giving the ovariectomized female incentive properties. The living female can be replaced with female odor. Sexual experience did not have any long-term effects on the female's incentive value, but immediately preceding limited sexual activity enhanced it     

Rhythmical body movement in sleep: a brief review and treatment study

Vigorous and damaging head-banging and head and body-rocking can occur in normal subjects of average intelligence before and during sleep. Reports of behavioural treatments for this are reviewed. Data from the present case and others suggest that waking plus efficient response prevention is sufficient to substantially reduce or eliminate the activity even when the treatment has been withdrawn for up to one year. The aetiology of the activity is not understood. However, this case suggests that head- and body-rolling, when long-established, need not enhance the quality of sleep since this was unimpaired on completion of treatment and was possibly even improved by the elimination of the movements. The present case also demonstrates that the behaviour can be treated successfully even when considerable environmental stresses occur.