Habituation or Normalization? Experiential and Respiratory Recovery From Voluntary Hyperventilation in Treated Versus Untreated Patients With Panic Disorder

Psychophysiological theories postulate respiratory dysregulation as a mechanism contributing to panic disorder (PD). Additionally, symptomatic and respiratory recovery from voluntary hyperventilation (HVT-recovery) have been shown to lag in PD and it is unclear if HVT-recovery normalizes with treatment. Thirty-seven panic disorder patients were randomized to hypoventilation therapy (TX, n = 20) or waitlist control (WL, n = 17) (Meuret et al., 2008). In a secondary analysis, their HVT-recovery was analyzed at pre- and post-TX/WL, compared to 29 healthy controls (HC). HVT included three phases: 5-min baseline, 3-min hyperventilation, and 8-min recovery. HVT-elicited symptom severity and anxiety were rated following each phase, and end-tidal PCO₂ and respiratory rate (RR) were recorded throughout. Treatment, compared to WL, was highly effective in reducing PD pathology (d = 2.21, Meuret et al., 2008). At pre-TX/WL, PD demonstrated delayed HVT-recovery PCO₂ and higher RR. Treated patients demonstrated normalization of HVT-recovery for PCO₂ and RR; however, improvements of HVT-recovery for symptom severity and anxiety did not differ between TX and WL. Results replicate pretreatment HVT respiratory recovery abnormalities in PD and further demonstrate normalization, comparable to HC, following successful treatment. The results provide support for respiratory dysregulation as a feature of PD and demonstrate the utility of HVT respiratory recovery as treatment outcome measure for respiration-based PD therapy.     

Robust inference with binary data

In this paper robustness properties of the maximum likelihood estimator (MLE) and several robust estimators for the logistic regression model when the responses are binary are analysed. It is found that the MLE and the classical Rao's score test can be misleading in the presence of model misspecification which in the context of logistic regression means either misclassification's errors in the responses, or extreme data points in the design space. A general framework for robust estimation and testing is presented and a robust estimator as well as a robust testing procedure are presented. It is shown that they are less influenced by model misspecifications than their classical counterparts. They are finally applied to the analysis of binary data from a study on breastfeeding.The author is partially supported by the Swiss National Science Foundation. She would like to thank Rand Wilcox, Eva Cantoni and Elvezio Ronchetti for their helpful comments on earlier versions of the paper, as well as Stephane Heritier for providing the routine to compute the OBRE.     

Evaluation of a group program designed to increase androgyny in feminine women

The effectiveness of a group treatment program designed to increase androgyny in feminine women was examined. The full treatment (FT) incorporated the principles of assertiveness training and consciousness raising, and was compared to a discussion-orientated alternate treatment (DO) and a wait-list control (WL). Fifty-one female subjects who scored feminine on the Bem Sex-Role Inventory participated in this study. Pre- and posttreatment measures of sex-role orientation, assertiveness, and the attainment of individual goals were obtained. Two-month and 1-year follow-up data were also collected. At the posttest, the FT group was more assertive than the DO and WL groups, and higher than the WL group in the attainment of individual goals. No posttest differences were found among the groups on sex-role orientation. These findings were reversed by the 2-month follow-up such that the FT was more androgynous and more masculine than the WL group, while the differences between groups in assertiveness and personal goal attainment had dissipated. The 1-year follow-up revealed the FT group to be superior to the WL group in androgyny, masculinity, and assertiveness.Appreciation is extended to N. J. Chehayeb, Brenda Barker, and Jimmie Eaker for their assistance in the data collection for this study. The study is based in part on the first author's doctoral dissertation submitted to Southern Illinois University under the supervision of the third author.     

Virtual reality exposure therapy and standard (in vivo) exposure therapy in the treatment of fear of flying

This controlled clinical trial tested virtual reality exposure (VRE) therapy for the fear of flying (FOF), a relatively new and innovative way to do exposure therapy, and compared it to standard (in vivo) exposure therapy (SE) and a wait list (WL) control with a 6- and 12-month follow-up. Eighty-three participants with FOF were randomly assigned to VRE, SE, or WL. Seventy-five participants, 25 per group, completed the study. Twenty-three WL participants completed randomly assigned treatment following the waiting period. Treatment consisted of 4 sessions of anxiety management training followed either by exposure to a virtual airplane (VRE) or an actual airplane at the airport (SE) conducted over 6 weeks. Results indicate that VRE was superior to WL on all measures, including willingness to fly on the posttreatment flight (76% for VRE and SE; 20% for WL). VRE and SE were essentially equivalent on standardized questionnaires, willingness to fly, anxiety ratings during the flight, self-ratings of improvement, and patient satisfaction with treatment. Follow-up assessments at 6 and 12 months indicated that treatment gains were maintained, with more than 70% of respondents from both groups reporting continued flying at follow-up. Based on these findings, the use of VRE in the treatment of FOF was supported in this controlled study, suggesting that experiences in the virtual world can change experiences in the real world.     

Bayesian Modal Estimation for the One-Parameter Logistic Ability-Based Guessing (1PL-AG) Model

The calibration of the one-parameter logistic ability-based guessing (1PL-AG) model in item response theory (IRT) with a modest sample size remains a challenge for its implausible estimates and difficulty in obtaining standard errors of estimates. This article proposes an alternative Bayesian modal estimation (BME) method, the Bayesian Expectation-Maximization-Maximization (BEMM) method, which is developed by combining an augmented variable formulation of the 1PL-AG model and a mixture model conceptualization of the three-parameter logistic model (3PLM). By comparing with marginal maximum likelihood estimation (MMLE) and Markov Chain Monte Carlo (MCMC) in JAGS, the simulation shows that BEMM can produce stable and accurate estimates in the modest sample size. A real data example and the MATLAB codes of BEMM are also provided.     

Effects of communication apprehension,familiarity of partner,and topic on selected “women's language” features

In keeping with Lakoff's (1975) notion that the use of women's language (WL) conveys uncertainty on the part of the speaker, the influence of communication apprehension, familiarity of partner, and topic on the use of selected WL forms was investigated. In dyadic conversation with a female friend or stranger, 71 female university students, who had completed the Personal Report of Communication Apprehension—Long, discussed a familiar or an unfamiliar topic. Multiple-regression analyses revealed that (1) communication apprehension was positively related to the use of question intonation, (2) familiarity of topic and partner were negatively related to the use of hedges, and (3) familiarity of topic was positively related to the use of intensifiers. There were no intercorrelations of the linguistic forms. These results challenge the notion that WL forms actually cohere to form a kind of language and suggest that the influence of social and psychological variables on the use of WL is much more complex and multifaceted than Lakoff believed.This article is based on portions of an Honour's thesis completed by the second author, and was presented at the Annual Convention of the Canadian Psychological Association held in Ottawa, Ontario, June 1990.     

Wrongful Life and Abortion

According to theories of wrongful life (WL), the imposition upon a child of an existence of poor quality can constitute an act of harming, and a violation of the child’s rights. The idea that there can be WLs may seem intuitively compelling. But, as this paper argues, liberals who commit themselves to WL theories may have to compromise some of their other beliefs. For they will thereby become committed to the claim that some women are under a stringent moral duty to have an abortion: a duty that could, without injustice, at least sometimes be enforced by the state. WL theories in other words imply that some women will lack a right to choose, under which both the decision to abort, and the decision to carry the fetus to term, are protected against interference. The paper exposes a dilemma, then, for liberals who are committed both to (a) the rights of future people not to be subjected to a harmful existence, and (b) the rights of women to refuse an abortion.     

Efficacy of Cognitive Therapy for Body Dysmorphic Disorder: A Randomized Controlled Pilot Trial

Dysfunctional cognitive processes and maladaptive interpersonal patterns have been postulated to maintain body dysmorphic disorder (BDD). The present trial evaluated CT for BDD (CT-BDD), which includes modules targeting maladaptive cognitive processing in BDD, as well as elements of schema therapy related to interpersonal problems. We investigated whether (a) CT-BDD is effective, as compared with a wait-list (WL) group at Week 12; (b) outcome of CT-BDD is maintained at posttreatment and 3- and 6-months follow-up; and (c) whether changes in shame and insight mediate changes in BDD symptom severity. Forty adults with BDD were randomized to 36 weeks immediate CT-BDD (n = 21), or to 12-week WL (n = 19). At Week 12, immediate CT-BDD was significantly superior to WL in clinician-rated BDD symptom severity, insight, self-reported BDD symptoms, shame, depression, general symptomatology, and life satisfaction. Changes in outcomes were associated with moderate to large effect sizes at Week 12. Reductions in shame and increase in insight separately mediated changes in BDD symptom severity during treatment at Week 12. From baseline to posttreatment, significant improvements occurred within CT-BDD in clinician-rated symptom severity, insight, depression, global functioning, self-reported BDD symptoms, shame, depression, general symptomatology, and life satisfaction. At posttreatment, improvements were associated with large effect sizes and were maintained at 3- and 6-month follow-up. Preliminary results support the efficacy of CT-BDD. Addressing interpersonal problems in addition to cognitive dysfunctions may increase the benefit of CBT for BDD patients.     

A Randomized Clinical Trial of Cognitive-Behavioral Therapy and Applied Relaxation for Adults With Generalized Anxiety Disorder

This randomized clinical trial compared cognitive-behavioral therapy (CBT), applied relaxation (AR), and wait-list control (WL) in a sample of 65 adults with a primary diagnosis of generalized anxiety disorder (GAD). The CBT condition was based on the intolerance of uncertainty model of GAD, whereas the AR condition was based on general theories of anxiety. Both manualized treatments were administered over 12 weekly 1-hour sessions. Standardized clinician ratings and self-report questionnaires were used to assess GAD and related symptoms at pretest, posttest, and at 6-, 12-, and 24-month follow-ups. At posttest, CBT was clearly superior to WL, AR was marginally superior to WL, and CBT was marginally superior to AR. Over follow-up, CBT and AR were equivalent, but only CBT led to continued improvement. Thus, direct comparisons of CBT and AR indicated that the treatments were comparable; however, comparisons of each treatment with another point of reference (either waiting list or no change over follow-up) provided greater support for the efficacy of CBT than AR.     

Written exposure as an intervention for PTSD: A randomized clinical trial with motor vehicle accident survivors

The present study examined the efficacy of a brief, written exposure therapy (WET) for posttraumatic stress disorder (PTSD). Participants were 46 adults with a current primary diagnosis of motor vehicle accident-related PTSD. Participants were randomly assigned to either WET or a waitlist (WL) condition. Independent assessments took place at baseline and 6-, 18-, and 30-weeks post baseline (WL condition not assessed at 30 weeks). Participants assigned to WET showed significant reductions in PTSD symptom severity at 6- and 18-week post-baseline, relative to WL participants, with large between-group effect sizes. In addition, significantly fewer WET participants met diagnostic criteria for PTSD at both the 6- and 18-week post-baseline assessments, relative to WL participants. Treatment gains were maintained for the WET participants at the 30-week post baseline assessment. Notably, only 9% of participants dropped out of WET and the WET participants reported a high degree of satisfaction with the treatment. These findings suggest that a brief, written exposure treatment may efficaciously treat PTSD. Future research should examine whether WET is efficacious with other PTSD samples, as well as compare the efficacy of WET with that of evidence-based treatments for PTSD.     

四参数Logistic加权模型下被试能力稳健估计

设计项目参数、被试得分已知的测验情境,在两、三、四参数Logistic加权模型下进行能力估计,发现被试得分等级之间的能力步长存在着均匀的步长间距,被试得分能较好的反映多级记分的分数加权作用。两参数Logistic加权模型下会出现被试参数估计扰动现象,猜测现象会导致能力高估现象,失误现象会导致能力低估现象;三参数Logistic加权模型c型下能力高估现象未出现或不明显;三参数Logistic加权模型γ型下能力低估现象未出现或不明显;四参数Logistic加权模型下被试能力高估现象和低估现象都未出现或不明显,四参数Logistic加权模型是被试能力稳健性估计较好的方法。     

Heart rate changes accompanying jaw movement Pavlovian conditioning in rabbits: Concomitant blood pressure adjustments and effects of peripheral autonomic blockade

Two experiments were conducted to ascertain the cardiovascular accompaniments of differential Pavlovian jaw movement (JM) conditioning. The first examined the blood pressure (BP) changes that accompany the tachycardiac conditioned responses (CRs) associated with JM conditioning. The BP response in all instances consisted of a depressor response that was greater to the reinforced CS+ than CS-, although the magnitude of the CR was quite small. The second experiment determined the effects of peripheral autonomic antagonists on the cardiac accelerations associated with JM conditioning. It was found that the peripheral vagal antagonist methyl scopolamine completely abolished responses to both CS+ and CS-, whereas atenolol, a beta adrenergic antagonist, augmented the response, compared to saline control injections. The JM responses were also affected by the autonomic blockades, with minimal responding occurring in the scopolamine group but slightly more JM CRs in the atenolol group, compared to saline control animals. These results suggest that the major cardiovascular response to an appetitive stimulus, which evokes JM conditioning, consists of cardiac accelerations with the BP depressor responses playing a minimal, if any, role. Moreover, these conditioned cardiac increases appear to be due solely to the release of vagal inhibition.     

Heart Rate Changes Accompanying Jaw Movement Pavlovian Conditioning in Rabbits: Concomitant Blood Pressure Adjustments and Effects of Peripheral Autonomic Blockade

Two experiments were conducted to ascertain the cardiovascular accompaniments of differential Pavlovian jaw movement (JM) conditioning. The first examined the blood pressure (BP) changes that accompany the tachycardiac conditioned responses (CRs) associated with JM conditioning. The BP response in all instances consisted of a depressor response that was greater to the reinforced CS+ than CS-, although the magnitude of the CR was quite small. The second experiment determined the effects of peripheral autonomic antagonists on the cardiac accelerations associated with JM conditioning. It was found that the peripheral vagal antagonist methyl scopolamine completely abolished responses to both CS+ and CS-, whereas atenolol, a beta adrenergic antagonist, augmented the response, compared to saline control injections. The JM responses were also affected by the autonomic blockades, with minimal responding occurring in the scopolamine group but slightly more JM CRs in the atenolol group, compared to saline control animals. These results suggest that the major cardiovascular response to an appetitive stimulus, which evokes JM conditioning, consists of cardiac accelerations with the BP depressor responses playing a minimal, if any, role. Moreover, these conditioned cardiac increases appear to be due solely to the release of vagal inhibition.     

Using a Kinect sensor to acquire biological motion: Toolbox and evaluation

Biological motion (BM) is the movement of animate entities, which conveys rich social information. To obtain pure BM, researchers nowadays predominantly use point-light displays (PLDs), which depict BM through a set of light points (e.g., 12 points) placed at distinct joints of a moving human body. Most prevalent BM stimuli are created by state-of-the-art motion capture systems. Although these stimuli are highly precise, the motion capture system is expensive and bulky, and its process of constructing a PLD-based BM is time-consuming and complex. These factors impede the investigation of BM mechanisms. In this study, we propose a free Kinect-based biological motion capture (KBC) toolbox based on the Kinect Sensor 2.0 in C++. The KBC toolbox aims to help researchers acquire PLD-based BM in an easy, low-cost, and user-friendly way. We conducted three experiments to examine whether KBC-generated BM can genuinely reflect the processing characteristics of BM: (1)?Is BM from this source processed globally in vision? (2)?Does its BM (e.g., from the feet) retain detailed local information? and (3)?Does the BM convey emotional information? We obtained positive results in response to all three questions. Therefore, we think that the KBC toolbox can be useful in generating BM for future research.     

Economic practices of Jesus movement groups

This paper examines in detail the multitude of ways used by Jesus Movement organizations to raise money to fund their many activities. The research was provoked by sharp differences between fund‐raising methods used by the two largest and well known JM organizations—the Children of God (now called The Family) and Christ Communal Organization (a pseudonym for a group called Shiloh). The COG mainly relied on various forms of public solicitation, while Shiloh depended on working for others and themselves in an effort to become self‐supporting. Seven other JM groups were examined to find out what patterns of support were most prevalent, and to examine possible relationships between sustenance activities and theological developments within the groups. A large number of experimental approaches were taken by JM groups trying to sustain themselves during their sometimes tumultuous histories, leading to a number of general conclusions.     

Enhanced encoding of the co-actor's target stimuli during a shared non-motor task

Task co-representation has been proposed to rely on the motor brain areas’ capacity to represent others’ action plans similarly to one's own. The joint memory (JM) effect suggests that working in parallel with others influences the depth of incidental encoding: Other-relevant items are better encoded than non-task-relevant items. Using this paradigm, we investigated whether task co-representation could also emerge for non-motor tasks. In Experiment 1, we found enhanced recall performance to stimuli relevant to the co-actor also when the participants’ task required non-motor responses (counting the target words) instead of key-presses. This suggests that the JM effect did not depend on simulating the co-actor's motor responses. In Experiment 2, direct visual access to the co-actor and his actions was found to be unnecessary to evoke the JM effect in case of the non-motor, but not in case of the motor task. Prior knowledge of the co-actor's target category is sufficient to evoke deeper incidental encoding. Overall, these findings indicate that the capacity of task co-representation extends beyond the realm of motor tasks: Simulating the other's motor actions is not necessary in this process.     

Does forgiving in a collectivistic culture affect only decisions to forgive and not emotions? REACH forgiveness collectivistic in Indonesia

According to some theorising, in collectivistic societies, forgiveness is mainly enacted to maintain relationships, not engender emotional transformation. This present study was designed to explore whether forgiveness affects decisional and emotional forgiveness in Indonesia, a country categorised as collectivistic. The evidence-based REACH Forgiveness psychoeducational group intervention was adapted to collectivistic culture (REACH forgiveness collectivistic; REACH-FC), and its efficacy was assessed in a randomised controlled trial. Undergraduates in Indonesia (N = 97; 24 male; 73 female; ages 16–21) were randomly assigned within a 2 × 3(S) quasi-experimental repeated-measures design comparing immediate treatment (IT) and waiting list (WL) conditions [Condition (IT, WL) × Time ([S] 3 time points). Harmonious value, a personality variable assessing the strength of participants' desire for group harmony, was the covariate. The condition × time (S) interactions for both decisional and emotional forgiveness were significant, challenging some previous literature. Clearly, not all forms of collectivism have similar effects when individuals and communities deal with transgressions.     

A randomized clinical trial comparing affect regulation and social problem-solving psychotherapies for mothers with victimization-related PTSD

Addressing affect dysregulation may provide a complementary alternative or adjunctive approach to the empirically supported trauma memory processing models of cognitive behavior therapy (CBT) for posttraumatic stress disorder (PTSD). A CBT designed to enhance affect regulation without trauma memory processing—trauma affect regulation: guide for education and therapy (TARGET)—was compared to present centered therapy (PCT) and wait-list (WL) conditions in a randomized clinical trial with 146 primarily low-income and ethnoracial minority mothers with PTSD. TARGET achieved statistically and clinically significant improvement on PTSD and affect regulation measures compared to WL, with more consistent and sustained (over a 6-month follow-up period) evidence of improvement than PCT. Drop-out rates (~ 25%) were comparable in TARGET and PCT, similar to those previously reported for trauma memory processing CBTs. Symptom worsening was rare (2–8%) and transient. Affect regulation-based CBT without trauma memory processing warrants further research as a potentially efficacious therapy for victimization-related PTSD.     

Bacterial Melanin Improves Cognitive Impairment Induced by Cerebral Hypoperfusion in Rats

The effect of bacterial melanin (BM) solution on learning and memory impairment induced by chronic cerebral hypoperfusion in rats was studied. Male rats were injected intramuscularly with BM solution on the second day after bilateral permanent occlusion of the common carotid artery. Rats received 6 mg/ml (170 mg/kg) BM and performed significantly better in cognition tests compared with controls. The present findings demonstrate that the beneficial effects of BM injection on cognitive functions may be due to preventing neuropathological alterations, suppressing the inflammation process, stimulating vascularization and inhibiting oxidative damage. Obtained data suggest that BM has therapeutic potential for the treatment of neurodegeneration caused by ischemia.     

The effects of the Triple P-Positive Parenting Program on preschool children with co-occurring disruptive behavior and attentional/hyperactive difficulties

Two variants of a behavioral family intervention (BFI) program known as Triple P were compared using 87 preschoolers with co-occurring disruptive behavior and attentional/hyperactive difficulties. Families were randomly allocated to enhanced BFI (EBFI), standard BFI (SBFI), or a waitlist (WL) control group. At postintervention both BFI programs were associated with significantly lower levels of parent-reported child behavior problems, lower levels of dysfunctional parenting, and greater parental competence than the WL condition. The EBFI condition was also associated with significantly less observed child negative behavior in comparison to the WL. The gains achieved at postintervention were maintained at 1-year follow-up. Contrary to predictions, the enhanced program was not shown to be superior to the standard program using any of the outcome measures at either postintervention or follow-up. Each of the programs produced significant reductions in children's co-occurring disruptive behavior and attentional/hyperactive difficulties with 80% of the children showing clinically reliable improvement in observed negative behavior from preintervention to follow-up.