Smoking,Methylation at AHRR,and Recidivism Risk in a Community Correction Sample of Individuals at High Risk for Recidivism

Individuals supervised by community correction programs have a high rate of tobacco use and high frequency of tobacco dependence. As compared with supervisees without tobacco dependence, probationers and parolees with tobacco dependence were more likely to abuse other substances and report poorer health. In this sample of 374 predominantly felon and repeat offenders, at high risk for recidivism, over 95% of subjects smoked or used other tobacco products, 87% were actively smoking at the time of interview, and 70% met criteria for lifetime tobacco dependence. Seventy-four percent had DNA demethylation, defined as methylation less than 83%, at the aryl hydrocarbon receptor repressor (AHRR) residue interrogated by cg0557592 at the time of interview. Seventy-eight percent exhibited four-year recidivism. Demethylation was associated with four-year recidivism in women, but not men. These findings suggest that methylation at cg05575921 serves as a semi-quantitative measure of both recent use and lifetime burden, that community correction populations continue to smoke at high risk, that measurement of methylation may add to the identification of female offenders at risk for recidivism, and that treatments to assist in cessation efforts are desperately needed. Copyright © 2015 John Wiley & Sons, Ltd.     

A Direct Method of Assessing Underlying Cognitive Risk for Adolescent Depression

An enduring tendency towards negative thinking is thought to increase vulnerability for future depression. However, it has not been possible to assess this tendency in non-depressed mood states. We examined if response latency to endorse dysfunctional attitudes is associated with depressive outcomes in a longitudinal study. A sample of young people at familial risk of depression (N?=?252, aged 10–19, 56.3 % female) completed a computer-administered dysfunctional attitude scale. The main outcome measure was the difference in reaction time to agree versus disagree with dysfunctional attitudes. Cross-sectional differences between current and previous depression and no psychiatric disorder groups as well as longitudinal associations with depressive symptoms were examined. Young people with current and previous depression were quicker to agree with dysfunctional attitudes than those without disorder. In young people free from depressive disorder, faster agreements with dysfunctional attitudes were specifically associated with increased depressive symptoms over time. Self-reported dysfunctional attitudes did not differentiate the formerly depressed and no disorder groups and showed a longitudinal association with depressive symptoms for older adolescents only. Reaction time to endorse dysfunctional attitudes may indicate changes in affective processing that represent an early risk for future depression that is not indexed by self-report measures of negative thought.     

False Memories in Individuals at Risk for Developing an Eating Disorder

In the present study, the authors used the Roediger and McDermott paradigm (H. L. Roediger & K. B. McDermott, 1995) to examine the creation of false memories in individuals at risk for developing an eating disorder. Thirty-three controls and 34 individuals at risk for eating disorders studied 6 word lists taken from the paradigm. Three lists were food related (bread, fruit, sweet), and 3 were not food related (king, doctor, black). Both groups produced false memories (i.e., recalled or recollected words that were not presented in the lists), and controls actually produced more false memories than the at-risk individuals produced in the recall of the food-related items. Groups did not differ in their recall of items not related to food.     

高低自我监控者在不同互动情境中的被洞悉错觉

用Snyder的自我监控量表,从大学生中筛选出典型高低自我监控者。要求他们不动声色地喝下1杯醋和4杯水,而后,让观众根据他们的表现去辨别饮料的味道,并让被试预测可能猜中的人数。在实验1中,被试和观众以录像为媒介间接的互相推测;在实验2中,被试和观众现场直接的互相推测。两个实验都包括高低自我监控者各21名。实验结果表明,自我监控水平对被洞悉错觉有明显的影响,在直接和间接两种互动情境中,低自我监控者的被洞悉错觉都比高自我监控者强烈。互动情境对高自我监控者有明显的影响,在间接的互动中,高自我监控者出现了明显的被洞悉错觉;而在直接的互动情境中,低自我监控者的被洞悉错觉依然非常明显,高自我监控者则趋于消失     

Affective Functioning Among Early Adolescents at High and Low Familial Risk for Depression and Their Mothers: A Focus on Individual and Transactional Processes across Contexts

This study aimed to characterize affective functioning in families of youth at high familial risk for depression, with particular attention to features of affective functioning that appear to be critical to adaptive functioning but have been underrepresented in prior research including: positive and negative affect across multiple contexts, individual and transactional processes, and affective flexibility. Interactions among early adolescents (ages 9–14) and their mothers were coded for affective behaviors across both positive and negative contexts. Primary analyses compared never-depressed youth at high (n = 44) and low (n = 57) familial risk for depression. The high risk group showed a relatively consistent pattern for low positive affect across negative and positive contexts at both the individual and transactional level. In contrast to prior studies focusing on negative contexts that did not support disruptions in negative affect among high risk youth, the data from this study suggest variability by context (i.e. increased negativity in a positive, but not negative, context), and individual vs. transactional processes (e.g., negative escalation). Findings are discussed in concert with attention to affect flexibility, contextual and transactional factors.     

高、低强迫症状个体的词语再认差异

比较了高强迫症状（High obsessive compulsive symptom, HOC）和低强迫症状（Low obsessive compulsive symptom, LOC）被试对于不同类型词语（强迫症敏感词、情绪词和中性词）再认成绩和记忆信心的差异。结果发现,HOC组记忆保存量显著低于LOC组（p<0.05）,表明HOC组对强迫症敏感词存在一定的偏好;通过对被试反应信心的检测和信号侦察论的应用,发现HOC组对中性词再认正误的判断觉察能力（d’值）低于LOC组（边缘显著：p＝0.054）;在正确反应信心上,被试类型和词语类型间存在交互作用,F(1,22)=4.60,p<0.05。本研究认为HOC组辨别能力的缺损可能导致其记忆信心方面的降低,这种假设还需要进一步的认知和脑功能研究来证实。     

Processing Fat-Related Information in Individuals at Risk for Developing an Eating Disorder

The authors examined the effect that being at risk for developing an eating disorder has on the lexical processing of words related to fat and words not related to fat. Individuals (n = 17) at risk for developing an eating disorder were compared with controls (n = 31) using a lexical decision task in which fat-related words (e.g., large), unrelated words (e.g., fair), neutral words (e.g., post), and pseudowords (e.g., flirp) were given. The results revealed an expected Group x Stimuli interaction for reaction times indicating that at-risk individuals were significantly faster at processing fat-related words than words unrelated to fat. The authors discuss these results within the context of how fat-related stimuli are processed in at-risk individuals and how models of information processing can aid in the interpretation and understanding of eating disorders.     

高低强迫清洗倾向个体对负性情绪注意偏向的差异

摘 要 本研究采用返回抑制范式,以诱发厌恶、恐惧和中性情绪的图片为线索,考察高、低强迫清洗倾向个体对负性情绪刺激注意偏向的差异及其发生机制。结果表明：（1）被试对诱发厌恶和恐惧的图片均产生了注意偏向且注意偏向是由注意解除困难所引起;（2）被试对诱发厌恶图片的注意偏向程度显著大于对诱发恐惧图片的注意偏向程度;（3）高、低强迫清洗倾向个体对诱发厌恶和恐惧图片的注意偏向程度之间的组间差异均不显著。     

Interpretation of Ambiguous Information in Girls at Risk for Depression

Research has consistently documented that depressed individuals process information in a negatively biased manner. There is little evidence, however, concerning whether these biases represent risk factors for depression, as is hypothesized by cognitive models. In the present study we investigated whether a particular cognitive bias observed in currently depressed individuals, the tendency to interpret ambiguous information negatively, characterizes daughters of depressed mothers, a population known to be at increased risk for depression. Following a negative mood induction, young daughters of depressed and never-disordered mothers completed two information-processing tasks in which their interpretations of emotionally ambiguous stimuli were evaluated. Daughters of depressed mothers interpreted ambiguous words more negatively and less positively, and ambiguous stories more negatively, than did daughters of never-disordered mothers. These results provide support for cognitive vulnerability models of depression.     

Effect of Parenting and Peer Stressors on Cognitive Vulnerability and Risk for Depression among Youth

Parenting behaviors influence clinical depression among youth, but little is known about the developmental processes that may account for this association. This study investigated whether parenting is associated with the onset of clinical depression and depressive symptoms through negative cognitive style, particularly under conditions of high exposure to stressors, in a community sample of children and adolescents (N = 275; 59% girls). Observational methods were used to assess positive and negative parenting during a laboratory social-evaluative stressor task. Depressive symptoms and clinical depressive episodes were repeatedly assessed over an 18-month prospective follow-up period. Results supported a conditional indirect effect in which low levels of observed positive parenting during a youth stressor task were indirectly associated with an increased likelihood of experiencing an episode of depression and worsening depressive symptoms over the course of the study through youth negative cognitive style, but only for youth who also experienced a high number of peer stressors. These findings elucidate mechanisms through which problematic parenting may contribute to risk for the development of clinical depression during the transition into and across adolescence. Implications for depression interventions are discussed.     

抑郁症人群的心境一致性认知偏向

心境一致性认知偏向指的是抑郁病人的认知加工偏向负性情绪效价, 简称认知偏向。大量行为学、电生理学以及脑成像学的研究显示该认知偏向主要包括知觉偏向、注意偏向、记忆偏向以及解释偏向。该认知偏向以加工偏向负性、积极偏向缺失以及认知控制受损为特点, 且是杏仁核等边缘系统对负性信息过度激活、纹状体对正性信息激活不足以及额区激活模式异常三个相应脑机制协同作用的产物。目前此领域存在各认知偏向之间联系不清楚、认知偏向和抑郁症的因果关系难以确定以及各研究结果不一致等有待回答的问题, 这些重要问题值得引起该领域未来研究者的注意。     

高低创伤个体的Stroop干扰效应及性别差异研究

探讨高低创伤个体的认知干扰效应及性别差异。采用创伤事件终身经历问卷—学生版、PTSD检查表平时版来选取高低创伤被试,通过经典Stroop范式要求被试进行色—词辨别反应任务。结果显示：高低创伤被试间存在显著的差异,高创伤被试的反应时显著长于低创伤被试的反应时;高低创伤两组被试在任务类型上均存在显著差异,一致任务的反应时显著低于不一致任务的反应时;高创伤组被试在性别上存在显著差异,男性的反应时显著低于女性的反应时;创伤水平、性别与任务类型在Stroop效应干扰上存在交互作用。研究表明高创伤女性被试更容易受到认知干扰,Stroop任务的类型也对创伤被试产生一定作用。     

Creatine Supplementation and Cognitive Performance in Elderly Individuals

ABSTRACT

The purpose of this study was to examine the effect of creatine supplementation on the cognitive performance of elderly people. Participants were divided into two groups, which were tested on random number generation, forward and backward number and spatial recall, and long-term memory tasks to establish a baseline level. Group 1 (n?=?15) were given 5 g four times a day of placebo for 1 week, followed by the same dosage of creatine for the second week. Group 2 (n?=?17) were given placebo both weeks. Participants were retested at the end of each week. Results showed a significant effect of creatine supplementation on all tasks except backward number recall. It was concluded that creatine supplementation aids cognition in the elderly.     

抑郁症的计算机化认知行为治疗

计算机化认知行为治疗(computerized cognitive-behavioral therapy, CCBT), 即指通过电脑交互界面, 以清晰的操作步骤, 高度结构化的多种媒介互动方式(如网页、漫画、动画、视频、声音等)来表现认知行为治疗基本原则和方法的治疗方式。抑郁症的CCBT近年来在西方崭露头角, 目前Beating The Blues、MoodGYM、E-Couch和Good Days Ahead等抑郁症CCBT程序在西方使用较为广泛。从可行性分析上发现, 该疗法较受病人接纳、具有较高的成本效用和易用性; 现有实验研究证明了抑郁症采用CCBT是有效的, 但其有效性仍取决于诸多因素。以往研究存在着较少关注治疗有效性的内在机制、治疗效果差异较大、风险评估简化和被试选择偏向等问题, 建议未来研究应加强：(1)中介效应及机制研究; (2)以人为本的个性化服务研究; (3)风险评估与隐私保护研究; (4)在“弱势群体”中的研究与运用。最后, 对其在中国发展的必要性与可行性进行了展望。     

Opening the Creative Mind of High Need for Cognitive Closure Individuals through Activation of Uncreative Ideas

Drawing on the integrative system theory of creativity combining the person, process, and press perspectives, this research offers the first evidence of how high-need-for-cognitive-closure (NFC) individuals’ creative mind can be opened up, by making them become more cognizant of uncreative ideas as consensually invalid solutions to creative problems. A validation study was conducted to first establish the utility of a newly developed chocolate design task. In the second study, half of the participants were made aware of conventional chocolate designs by drawing these designs before generating a revolutionized design of chocolate; the other half did not have to draw out the conventional designs first. Results confirmed that, given the opportunity to cognize uncreative solutions, high-NFC participants who had a higher creative ideation potential became the most creative. Their low-NFC counterparts, however, did not seem to benefit from the trigger of uncreative solutions. The implication that holding onto a chronic motive to attain cognitive closure or epistemic certainty is not necessarily detrimental to creative performance was discussed.