Face and gaze processing in Prader‐Willi syndrome

A number of developmental disorders of genetic origin show atypical aspects of face processing. However, little is known about face processing in Prader‐Willi syndrome (PWS). PWS is of specific interest because it has two modes of inheritance (paternally derived deletion, DEL; maternal uniparental disomy, UPD) only one of which (UPD) is associated with an increased risk of autistic symptomology. We conducted electrophysiological (ERP) and behavioural measurements of face and eye‐gaze processing in individuals with PWS derived from both modes of inheritance. Our hypothesis that UPD PWS would show a pattern of deficits resembling those seen in autism was only partially confirmed. Although some individuals from both groups showed deficits, as a whole the UPD group (N=8) and the DEL group (N=8) did not differ on behavioural measures of face processing or autistic symptoms. In contrast, the effect of face orientation and gaze direction on the amplitude of the N170 ERP component differed between the two PWS sub‐types. Thus, while the behavioural tests did not discriminate between the UPD and deletion forms of the syndrome, electrophysiological measures of face processing did differentiate the groups.     

Implicit familiarity processing in congenital prosopagnosia

A particularly interesting and somewhat puzzling finding in the face‐processing literature is that, despite the absence of overt recognition of most faces, many patients with acquired prosopagnosia (AP) exhibit evidence of intact covert face recognition of the very same faces. This phenomenon has important implications for the understanding of the mechanism underlying AP and, by extension, the mechanism underlying normal face processing. Here, we set out to examine whether individuals with congenital prosopagnosia (CP) exhibit a similar dissociation between overt and covert face recognition. We first confirmed that all six of our CP individuals were significantly impaired in face recognition in comparison with controls. Participants then completed a matching task with both famous and unknown faces in which they decided whether two consecutive images have the same identity or not. Critically, the level of face familiarity was orthogonal to the task at hand and this enabled us to examine whether the familiarity of a face enhanced identity matching, a finding which would implicate implicit face processing. As expected, the CP individuals were slower and less accurate than the control participants. More importantly, like the controls, the CP individuals were faster and more accurate at matching famous compared with unknown faces. Also, for both groups, matching performance on unrecognized famous faces fell at an intermediate level between performance on explicitly recognized famous faces and faces which are unknown. These results provide the first solid evidence for the existence of implicit familiarity processing in CP and suggest that, despite the marked impairment in explicit face recognition, these individuals still have some familiarity representation which manifests in the form of covert recognition. We discuss possible models to account for the apparent dissociation of overt and covert face processing in CP.     

Distinct conflict resolution deficits related to different facets of Schizophrenia

An important issue in understanding the nature of conflict processing is whether it is a unitary or multidimensional construct. One way to examine this is to study whether people with impaired conflict processing exhibit a general pattern of deficits or whether they exhibit impairments in distinct aspects of conflict processing. One group who might exhibit conflict deficits are people with schizophrenia. Schizophrenia is a heterogeneous disorder, with one way to break down the heterogeneity of schizophrenia is to examine specific symptoms. Previous research has found that specific symptoms of schizophrenia are associated with specific deficits in conflict processing. In particular, disorganization is associated with increased response conflict, alogia is associated with increased retrieval conflict, and anhedonia is associated with increased emotional conflict. Moreover, there is evidence that different types of conflict processing are unassociated with each other. This evidence suggests that conflict processing is a multidimensional construct and that different aspects of schizophrenia are associated with impairments in processing different types of conflict.     

Face processing in autistics: Evidence for a generalised deficit?

Several studies have recently highlighted specific impairments in face processing in autistic subjects (memory for faces, recognition of emotional expressions, identity recognition of familiar faces). The goal of the present study was to explore whether there was a generalised face processing deficit in this population. A variety of tasks examining different, and possibly dissociative, aspects of face processing was investigated. The results of autistic subjects were compared with data from (a) a group of children with Down syndrome and (b) two individually matched control groups. The study suggests that autistic subjects are impaired in the various face processing tasks, but not always to the same extent.     

Neural bases and development of face recognition in autism

This paper critically examines the literature on face recognition in autism, including a discussion of the neural correlates of this ability. The authors begin by selectively reviewing the behavioral and cognitive neuroscience research on whether faces are represented by a "special" behavioral and neural system-one distinct from object processing. The authors then offer a neuroconstructivist model that attempts to account for the robust finding that certain regions in the inferior temporal cortex are recruited in the service of face recognition. This is followed by a review of the evidence supporting the view that face recognition is atypical in individuals with autism. This face-recognition deficit may indicate a continued risk for the further development of social impairments. The authors conclude by speculating on the role of experience in contributing to this atypical developmental pattern and its implications for normal development of face processing.     

Attitude change in face‐to‐face and computer‐mediated communication: private self‐awareness as mediator and moderator

Two types of social influence can be distinguished: norm‐based influence occurs when social identity is salient and interpersonal influence occurs when personal identity is salient. In two experiments the impact of trait and state private self‐awareness on interpersonal influence during face‐to‐face and computer‐mediated communication (CMC) was investigated. It is argued that interpersonal influence resulting from face‐to‐face communication is stronger than interpersonal influence resulting from CMC because CMC heightens state private self‐awareness. As a result, it leads to a focus on personal perceptions and thoughts which in turn reduces attitude change. Experiment 1 suggests that communication media may influence attitude change via private self‐awareness. Experiment 2 showed that trait private self‐awareness moderates the effect of communication media on interpersonal influence. Interpersonal influence was stronger in face‐to‐face communication than in CMC only for individuals higher in private self‐awareness. This finding indicates that the impact of situational variations of a concept can be limited to individuals who have a more elevated sense of private self‐awareness. Copyright © 2005 John Wiley & Sons, Ltd.     

Normal perception of Mooney faces in developmental prosopagnosia: Evidence from the N170 component and rapid neural adaptation

Individuals with developmental prosopagnosia (DP) have a severe difficulty recognizing the faces of known individuals in the absence of any history of neurological damage. These recognition problems may be linked to selective deficits in the holistic/configural processing of faces. We used two‐tone Mooney images to study the processing of faces versus non‐face objects in DP when it is based on holistic information (or the facial gestalt) in the absence of obvious local cues about facial features. A rapid adaptation procedure was employed for a group of 16 DPs. Naturalistic photographs of upright faces were preceded by upright or inverted Mooney faces or by Mooney houses. DPs showed face‐sensitive N170 components in response to Mooney faces versus houses, and N170 amplitude reductions for inverted as compared to upright Mooney faces. They also showed the typical pattern of N170 adaptation effects, with reduced N170 components when upright naturalistic test faces were preceded by upright Mooney faces, demonstrating that the perception of Mooney and naturalistic faces recruits shared neural populations. Our findings demonstrate that individuals with DP can utilize global information about face configurations for categorical discriminations between faces and non‐face objects, and suggest that face processing deficits emerge primarily at more fine‐grained higher level stages of face perception.     

Emotion processing deficits in the different dimensions of psychometric schizotypy

Schizotypy refers to a personality structure indicating “proneness” to schizophrenia. Around 10% of the general population has increased schizotypal traits, they also share other core features with schizophrenia and are thus at heightened risk for developing schizophrenia and spectrum disorders. A key aspect in schizophrenia‐spectrum pathology is the impairment observed in emotion‐related processes. This review summarizes findings on impairments related to central aspects of emotional processes, such as emotional disposition, alexithymia, facial affect recognition and speech prosody, in high schizotypal individuals in the general population. Although the studies in the field are not numerous, the current findings indicate that all these aspects of emotional processing are deficient in psychometric schizotypy, in accordance to the schizophrenia‐spectrum literature. A disturbed frontotemporal neural network seems to be the critical link between these impairments, schizotypy and schizophrenia. The limitations of the current studies and suggestions for future research are discussed.     

Staying vigorous until work is over: The role of trait vigour,day‐specific work experiences and recovery

Staying vigorous throughout the day is important for work‐related behaviour, subjective well‐being, and for effective functioning in the family domain. This study examined trait vigour (i.e. a person's general level of vigour), day‐specific workload (time pressure, work hours), and recovery resulting from unwinding during leisure time as predictors of day‐specific vigour as experienced at the end of the working day. Seventy‐five individuals from service and public administration organizations completed one general survey and daily surveys two times per day for five working days. Trait vigour, demographic variables and control variables (e.g. job control, home workload) were assessed in the general survey. Day‐specific level of vigour, day‐specific workload, and day‐specific recovery were measured in the daily survey. Analyses following a hierarchical linear modelling approach showed that trait vigour, day‐specific workload and recovery accumulated during the preceding evenings predicted an individual's level of vigour at the end of the working day, after controlling for a range of other variables (gender, age, job control, and home workload). Trait vigour and accumulated recovery experiences interacted significantly to predict vigour at the end of the working day, indicating that individuals high on trait vigour benefit most from recovery experienced over the course of several days.     

Animal,but not human,faces engage the distributed face network in adolescents with autism

Multiple hypotheses have been offered to explain the impaired face‐processing behavior and the accompanying underlying disruptions in neural circuitry among individuals with autism. We explored the specificity of atypical face‐processing activation and potential alterations to fusiform gyrus (FG) morphology as potential underlying mechanisms. Adolescents with high functioning autism (HFA) and age‐matched typically developing (TD) adolescents were scanned with sMRI and fMRI as they observed human and animal faces. In spite of exhibiting comparable face recognition behavior, the HFA adolescents evinced hypo‐activation throughout the face‐processing system in response to unfamiliar human, but not animal, faces. They also exhibited greater activation in affective regions of the face‐processing network in response to animal, but not human, faces. Importantly, this atypical pattern of activation in response to human faces was not related to atypical structural properties of the FG. This atypical neural response to human faces in autism may stem from abnormalities in the ability to represent the reward value of social (i.e. conspecific) stimuli.     

Sources of Variance in Personality Facets: A Multiple‐Rater Twin Study of Self‐Peer,Peer‐Peer,and Self‐Self (Dis)Agreement

ABSTRACT This study considered the validity of the personality structure based on the Five‐Factor Model using both self‐ and peer reports on twins' NEO‐PI‐R facets. Separating common from specific genetic variance in self‐ and peer reports, this study examined genetic substance of different trait levels and rater‐specific perspectives relating to personality judgments. Data of 919 twin pairs were analyzed using a multiple‐rater twin model to disentangle genetic and environmental effects on domain‐level trait, facet‐specific trait, and rater‐specific variance. About two thirds of both the domain‐level trait variance and the facet‐specific trait variance was attributable to genetic factors. This suggests that the more personality is measured accurately, the better these measures reflect the genetic structure. Specific variance in self‐ and peer reports also showed modest to substantial genetic influence. This may indicate not only genetically influenced self‐rater biases but also substance components specific for self‐ and peer raters' perspectives on traits actually measured.     

孤独症谱系障碍患者对种族情境中本异族面孔的眼动模式

本研究采用眼动技术探讨孤独症谱系障碍(ASD)患者对背景中的本异族面孔的加工特点。研究采用2（组别）×2（面孔种族）×3（背景）的混合设计,让16名16-25岁的ASD患者和17名生理年龄匹配的正常人完成变化检测任务,并记录他们的眼动。结果显示：与正常人相比,ASD患者的面孔辨别力更低;他们的眼动呈现更多的面孔-背景眼跳和更多的上下半脸眼跳;两组被试的上下半脸眼跳的次数受到面孔种族以及面孔和背景是否一致的影响。结论：在行为指标上,正常人出现了本族效应,而ASD患者没有出现本族效应;在眼动上,ASD患者呈现与正常人相似的面孔注视时间,但比正常人呈现更多的眼跳。面孔的背景影响了面孔辨别力以及上下半脸眼跳轨迹。     

Simulating the pattern of right-hemisphere-damaged patients for the processing of the alternative metaphorical meanings of words: evidence in favor of a cognitive resources hypothesis

Lately, many studies have suggested that communication impairments in brain-damaged individuals might be explained--at least in part--in terms of cognitive resource allocation. Reproducing a clinical pattern in normal subjects by using a dual-task treatment might be a way of evaluating the role of cognitive resources in the right hemisphere's contribution to verbal communication. This study suggests that the RH's presumed specific contribution to the processing of the alternative metaphorical meanings of words is, at least to some extent, the expression of the RH's complementary, and necessary, contribution to the pool of attentional resources needed for the most effortful processing.     

Bilingual infants excel at foreign‐language talker recognition

Bilingual and monolingual infants differ in how they process linguistic aspects of the speech signal. But do they also differ in how they process non‐linguistic aspects of speech, such as who is talking? Here, we addressed this question by testing Canadian monolingual and bilingual 9‐month‐olds on their ability to learn to identify native Spanish‐speaking females in a face‐voice matching task. Importantly, neither group was familiar with Spanish prior to participating in the study. In line with our predictions, bilinguals succeeded in learning the face‐voice pairings, whereas monolinguals did not. We consider multiple explanations for this finding, including the possibility that simultaneous bilingualism enhances perceptual attentiveness to talker‐specific speech cues in infancy (even in unfamiliar languages), and that early bilingualism delays perceptual narrowing to language‐specific talker recognition cues. This work represents the first evidence that multilingualism in infancy affects the processing of non‐linguistic aspects of the speech signal, such as talker identity.     

What is Overt and what is Covert in Congenital Prosopagnosia?

The term covert recognition refers to recognition without awareness. In the context of face recognition, it refers to the fact that some individuals show behavioural, electrophysiological or autonomic indices of recognition in the absence of overt, conscious recognition. Originally described in cases of people that have lost their ability to overtly recognize faces (acquired prosopagnosia, AP), covert face recognition has more recently also been described in cases of congenital prosopagnosia (CP), who never develop typical overt face recognition skills. The presence of covert processing in a developmental disorder such as CP is a particularly intriguing phenomenon, and its investigation is relevant for a variety of reasons. From a theoretical point of view, it is useful to help shed light on the cognitive and neural underpinnings of face recognition deficits. From a clinical point of view, it has the potential to aid the design of rehabilitation protocols aimed at improving face recognition skills in this population. In the current review we selectively summarize the recent literature on covert face recognition in CP, highlight its main findings, and provide a theoretical interpretation for them.     

What aspects of face processing are impaired in developmental prosopagnosia?

Developmental prosopagnosia (DP) is a severe impairment in identifying faces that is present from early in life and that occurs despite no apparent brain damage and intact visual and intellectual function. Here, we investigated what aspects of face processing are impaired/spared in developmental prosopagnosia by examining a relatively large group of individuals with DP (n = 8) using an extensive battery of well-established tasks. The tasks included measures of sensitivity to global motion and to global form, detection that a stimulus is a face, determination of its sex, holistic face processing, processing of face identity based on features, contour, and the spacing of features, and judgments of attractiveness. The DP cases showed normal sensitivity to global motion and global form and performed normally on our tests of face detection and holistic processing. On the other tasks, many DP cases were impaired but there was no systematic pattern. At least half showed deficits in processing of facial identity based on either the outer contour or spacing of the internal features, and/or on judgments of attractiveness. Three of the eight were impaired in processing facial identify based on the shape of internal features. The results show that DP is a heterogeneous condition and that impairment in recognizing faces cannot be predicted by poor performance on any one measure of face processing.     

从面孔模块到马赛克──视觉特异性加工的脑机制

“脑功能的模块性”是视觉乃至整个认知神经科学的研究热点。特异性的面孔加工模块被当作是认知模块假说的最好证据。但综述跨学科的正反两方面实验证据表明,视觉加工存在特异性,并没有普遍的模块式的亚单元,而是“马赛克”镶嵌式的组构。     

Computer‐Aided Psychotherapy for Anxiety Disorders: A Meta‐Analytic Review

Computer‐aided psychotherapy (CP) is said to (1) be as effective as face‐to‐face psychotherapy, while requiring less therapist time, for anxiety disorder sufferers, (2) speed access to care, and (3) save traveling time. CP may be delivered on stand‐alone or Internet‐linked computers, palmtop computers, phone‐interactive voice response, DVDs, and cell phones. The authors performed a meta‐analysis of 23 randomised controlled studies (RCTs) that compared CP with non‐CP in anxiety disorders: phobias, n = 10; panic disorder/agoraphobia, n = 9; PTSD, n = 3; obsessive–compulsive disorder, n = 1. Overall mean effect size of CP compared with non‐CP was 1.08 (95% confidence interval: 0.84–1.32). CP and face‐to‐face psychotherapy did not differ significantly from each other (13 comparisons, d = ?0.06). Much caution is needed when interpreting the findings indicating that outcome was unrelated to type of disorder, type of comparison group, mode of CP delivery (Internet, stand‐alone PC, palmtop), and recency of the CP system and that effect size decreased when more therapist time was replaced by the computer. Because CP as a whole was as effective as face‐to‐face psychotherapy, certain forms of CP deserve to be integrated into routine practice.     

Audio‐visual speech in noise perception in dyslexia

Individuals with developmental dyslexia (DD) may experience, besides reading problems, other speech‐related processing deficits. Here, we examined the influence of visual articulatory information (lip‐read speech) at various levels of background noise on auditory word recognition in children and adults with DD. We found that children with a documented history of DD have deficits in their ability to gain benefit from lip‐read information that disambiguates noise‐masked speech. We show with another group of adult individuals with DD that these deficits persist into adulthood. These deficits could not be attributed to impairments in unisensory auditory word recognition. Rather, the results indicate a specific deficit in audio‐visual speech processing and suggest that impaired multisensory integration might be an important aspect of DD.     

Face inversion disrupts the perception of vertical relations between features in the right human occipito‐temporal cortex

The impact of inversion on the extraction of relational and featural face information was investigated in two fMRI experiments. Unlike previous studies, the contribution of horizontal and vertical spatial relations were considered separately since they have been shown to be differentially vulnerable to face inversion (Goffaux & Rossion, 2007). Hence, inversion largely affects the perception of vertical relations (e.g. eye or mouth height) while the processing of features (e.g. eye shape and surface) and of horizontal relations (e.g. inter‐ocular distance) is affected to a far lesser extent. Participants viewed pairs of faces that differed either at the level of one local feature (i.e. the eyes) or of the spatial relations of this feature with adjacent features. Changes of spatial relations were divided into two conditions, depending on the vertical or horizontal axis of the modifications. These stimulus conditions were presented in separate blocks in the first (block) experiment while they were presented in a random order in the second event‐related (ER) experiment. Face‐preferring voxels located in the right‐lateralized middle fusiform gyrus (rMFG) largely decreased their activity with inversion. Inversion‐related decreases were more moderate in left‐lateralized middle fusiform gyrus (lMFG). ER experiment revealed that inversion affected rMFG and lMFG activity in distinct stimulus conditions. Whereas inversion affected lMFG processing only in featural condition, inversion selectively affected the processing of vertical relations in rMFG. Correlation analyses further indicated that the inversion effect (IE) observed in rMFG and right inferior occipital gyrus (rIOG) reliably predicted the large behavioural IE observed for the processing of vertical relations. In contrast, lMFG IE correlated with the weak behavioural IE observed for the processing of horizontal relations. Our findings suggest that face configuration is mostly encoded in rMFG, whereas more local aspects of face information, such as features and horizontal spatial relations drive lMFG processing. These findings corroborate the view that the vulnerability of face perception to inversion stems mainly from the disrupted processing of vertical face relations in the right‐lateralized network of face‐preferring regions (rMFG, rIOG).